| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2020: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2019: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
1) We generated mouse models of brain injury and confirmed that neuroblasts migrate to the periphery of the injury site. 2) We confirmed that Fyn and phosphorylated Fyn are expressed in neuroblasts heading for the injury site. 3) We confirmed that Reelin, an upstream signal of Fyn, is also expressed in the periphery of the injury site. 4) Experiments to suppress the expression of Fyn in neuroblasts suggested that Fyn is involved in the migration of newborn neurons to the site of brain injury.
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