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The basic and clinical research for spread and improvement of treatment results of sialendoscopic surgery

Research Project

Project/Area Number 18K16861
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 56050:Otorhinolaryngology-related
Research InstitutionTokyo Metropolitan Komagome Hospital (Clinical research laboratory) (2019-2021)
Tokyo Women's Medical University (2018)

Principal Investigator

Kondo Norio  東京都立駒込病院(臨床研究室), 耳鼻咽喉科・頭頸部腫瘍外科, 医長 (30773759)

Project Period (FY) 2018-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2021: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2020: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2019: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2018: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords唾液腺管内視鏡 / 唾石症 / 唾液腺管狭窄症 / 耳下腺 / 顎下腺 / シェーグレン症候群 / 反復性耳下腺炎 / ステノン管狭窄症 / ステノン管吻合 / 歯科用ワイヤー / YAGレーザー / 唾石 / 唾液腺内視鏡 / Ho-YAGレーザー / 治療成績
Outline of Final Research Achievements

In May 2018, we gave a presentation at the 119th annual meeting of the ORL Society of Janan as the title of "The landmark for removal of sialoliths using sialendoscopy alone in parotid gland sialolithiasis". In June 2018, we gave a presentation at the 80th annual meeting of the Society of Practical Otolaryngoloy as the title of "Diagnostic and treatment effects of sialendoscopy for patients with swelling of the parotid gland when sialoliths are undetected with computed tomography".We published a review article that is titled "Diagnosis of sialoliths and sialendoscopic surgery"(ENTONI,222: 18-24, 2018, in Japanese). In March 2022, we gave a presentation at the 31st annual meeting of the Japan Society of Head and Neck Surgery as the title of "Idiopathic Stensen’s duct stenosis: The stenotic site was resected and anastomosed after trying sialendoscopic surgery".

Academic Significance and Societal Importance of the Research Achievements

耳下腺唾石症について唾液腺内視鏡のみで摘出できる指標は唾石の大きさではなく唾石の存在部位でることが示された。具体的にはステノン管の咬筋中央より前方で摘出率が高く後方では摘出率が低くなることを学会で発表し啓蒙することができた。またこの内容は英文論文として既出の内容をSecondary Publicationとして掲載された(日耳鼻,122 (2):122-29. 2019)。CTで唾石が描出されず耳下腺腫脹を呈する場合の診断、治療方法、予後などを学会発表で示すことができた。ステノン管狭窄症の完全閉塞例では唾液腺管内視鏡のみでの治療は困難で外切開による手術が必要となる可能とを学会発表で示した。

Report

(5 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (7 results)

All 2022 2018

All Journal Article (4 results) (of which Peer Reviewed: 3 results) Presentation (3 results)

  • [Journal Article] The landmark for removal of sialoliths using sialendoscopy alone in parotid gland sialolithiasis2018

    • Author(s)
      Kondo N, Yoshihara T, Yamamura Y, Kusama K, Sakitani E, Seo Y, Tachikawa M, Kujirai K, Ono E, Maeda Y, Nojima T, Tamiya A, Sato E, Nonaka M
    • Journal Title

      Auris Nasusu Larynx

      Volume: 45 Issue: 2 Pages: 306-10

    • DOI

      10.1016/j.anl.2017.05.016

    • NAID

      130007606368

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Treatment outcomes of sialendoscopy for submandibular gland sialolithiasis: the minor axis of the sialolith is a regulative factor for the removal of sialoliths in the hilum of the submandibular gland using sialendoscopy alone2018

    • Author(s)
      Kondo N, Yoshihara T, Yamamura Y, Kusama K, Sakitani E, Seo Y, Tachikawa M, Kujirai K, Ono E, Maeda Y, Nojima T, Tamiya A, Sato E, Nonaka M
    • Journal Title

      Auris Nasusu Larynx

      Volume: 45 Issue: 4 Pages: 772-6

    • DOI

      10.1016/j.anl.2017.09.003

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] Diagnostic and treatment effects of sialendoscopy for patients with swelling of the parotid gland when sialoliths are undetected with computed tomography2018

    • Author(s)
      Kondo N, Yoshihara T, Yamamura Y, Kusama K, Sakitani S, Seo Y, Tachikawa M, Kujirai K, Ono E, Maeda Y, Nojima T, Tamiya A, Sato E, Nonaka M
    • Journal Title

      Auris Nasusu Larynx

      Volume: 45 Issue: 4 Pages: 880-4

    • DOI

      10.1016/j.anl.2017.11.004

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Journal Article] 唾石の診断と内視鏡下摘出術2018

    • Author(s)
      近藤律男、吉原俊雄
    • Journal Title

      ENTONI

      Volume: 222 Pages: 18-24

    • Related Report
      2018 Research-status Report
  • [Presentation] ステノン管切除吻合を行った特発性ステノン管狭窄症の1例2022

    • Author(s)
      近藤律男、福田 藍、野中 学
    • Organizer
      第31回頭頸部外科学会学術講演会
    • Related Report
      2021 Annual Research Report
  • [Presentation] 唾液腺内視鏡のみで摘出可能な耳下腺唾石に関する術前評価項目の検討2018

    • Author(s)
      近藤律男,吉原俊雄,山村幸江,草間 薫,崎谷恵理,瀬尾友佳子,立川麻也子,鯨井桂子,小野英莉香,戸塚大輔,野島知人,服部 藍,五島可奈子,野中 学
    • Organizer
      第119回日本耳鼻咽喉科学会学術講演会
    • Related Report
      2018 Research-status Report
  • [Presentation] CTで唾石が検出されない耳下腺腫脹に対する唾液腺内視鏡の有用性について2018

    • Author(s)
      近藤律男,吉原俊雄,山村幸江,立川麻也子,鯨井桂子,小野英莉香,戸塚大輔,野島知人,長島弘明,野中 学
    • Organizer
      第80回耳鼻咽喉科臨床学会学術講演会
    • Related Report
      2018 Research-status Report

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Published: 2018-04-23   Modified: 2023-01-30  

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