| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2021: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2020: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2019: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2018: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Outline of Final Research Achievements |
A special anastomosis technique was developed and implemented for the very small diameter, because the diameter of Biotube is 0.3 mm and that of rat intra-abdominal lymphatic duct is 0.2 mm. We found that inserting nylon monofilaments from 7-0 to 9-0 into the lymphatic vessels as guide nylon threads makes it easier to insert nylon monofilaments with larger diameters such as 6-0 and 5-0. This larger-diameter nylon monofilament was stented, and lymphatics were anastomosed successfully with Bio tubes using 11-0 and 12-0 micro needles. By this method, vessels with a diameter of 0.1 mm or less can be anastomosed successfully. The fact was reported and published in a paper. The immediate patency rate of Biotube is almost 100%, but long-term patency cannot be confirmed. It is considered to be caused by postoperative contracture awing to collagen characteristics.
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