Improving the histological weakness of transcutaneous implants in maxillofacial prosthetic treatment
| Project/Area Number |
18K17124
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 57050:Prosthodontics-related
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Project Period (FY) |
2018-04-01 – 2023-03-31
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| Project Status |
Completed (Fiscal Year 2022)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2019: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2018: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | インプラント / 軟組織 / 顎顔面補綴 |
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| Outline of Final Research Achievements |
Defects in the maxillofacial region are severe and complex. Implants are applied as a structural base for maxillofacial prostheses; however, the success rate of maxillofacial implants is currently low.
This study focused on the soft tissue around implants that penetrate the oral mucosa and skin. Epithelial and fibroblast cells from rat oral mucosa and back skin were collected and cultured on titanium plates. The maxillary first molars of rats were extracted, and experimental implants were placed.
Evaluation of peri-implant soft tissue sealing revealed that the predominant surface properties differed between the epithelium and connective tissue. Additionally, the soft tissue sealing ability around implants was found to be inferior to that of natural teeth. These findings suggest that improvement in the surface properties of the implant and the soft tissue sealing ability may affect the success of implant treatment.
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| Academic Significance and Societal Importance of the Research Achievements |
本研究結果は顎顔面インプラント治療の安定した提供、つまり、成功率の向上に寄与すると考える。さらに、今後の顎顔面補綴臨床を歯科発信の技術で大きく変革し、歯科医学・医療の目標である健康・福祉の向上に大きく貢献すると思われる。
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Report
(6 results)
Research Products
(24 results)
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[Journal Article] The need for polishing and occlusal adjustment of zirconia prostheses for wear on antagonist teeth2021
Author(s)
Tachibana Keishu, Atsuta Ikiru, Tsukiyama Yoshihiro, Kuwatsuru Rika, Morita Takehiro, Yoshimatsu Hiroya, Matsushita Yasuyuki, Narimatsu Ikue, Ayukawa Yasunori, Sawae Yoshinori, Koyano Kiyoshi
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Journal Title
Dental Materials Journal
Volume: advpub
Issue: 0
Pages: 650-656
DOI
NAID
ISSN
0287-4547, 1881-1361
Related Report
Peer Reviewed / Open Access
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[Journal Article] Novel Application Method for Mesenchymal Stem Cell Therapy Utilizing Its Attractant-Responsive Accumulation Property2019
Author(s)
Ueda Nobuyuki, Atsuta Ikiru, Ayukawa Yasunori, Yamaza Takayoshi, Furuhashi Akihiro, Narimatsu Ikue, Matsuura Yuri, Kondo Ryosuke, Watanabe Yu, Zhang Xiaoxu, Koyano Kiyoshi
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Journal Title
Applied Sciences
Volume: 9
Issue: 22
Pages: 4908-4908
DOI
Related Report
Peer Reviewed / Open Access
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