Pharmacokinetic analysis of tumors in the maxillofacial region using Dual Energy CT
Project/Area Number |
18K17170
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Research Category |
Grant-in-Aid for Early-Career Scientists
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Allocation Type | Multi-year Fund |
Review Section |
Basic Section 57060:Surgical dentistry-related
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Research Institution | Kyushu University |
Principal Investigator |
|
Project Period (FY) |
2018-04-01 – 2022-03-31
|
Project Status |
Completed (Fiscal Year 2021)
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Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2021: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2020: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2019: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2018: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
Keywords | dual energy CT / 顎顔面領域 / 扁平上皮癌 / 頸部リンパ節転移 / 頭頸部 / perfusion CT / Dual Energy CT / 顎顔面腫瘍 / Perfusion / Permeability |
Outline of Final Research Achievements |
We established a Dual Energy CT (DECT) protocol in the maxillofacial region and investigated whether parameters calculated from DECT images are effective in the diagnosis of metastatic lymph nodes of squamous cell carcinoma. Cervical lymph nodes larger than 5 mm were included in the study to determine the variation in CT values at 40, 70, and 100 keV and iodine content within the lymph nodes, and to correlate them with pathology. Metastatic lymph nodes tended to have significantly smaller contrast uptake than non-metastatic nodes, suggesting that DECT is likely to be associated with pathological changes within metastatic lymph nodes.
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Academic Significance and Societal Importance of the Research Achievements |
顎顔面領域において、DECT画像から算出したパラメータが扁平上皮癌の転移リンパ節の診断に有用である可能性が示唆された。
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Report
(4 results)
Research Products
(4 results)
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[Presentation] 動静脈奇形の一例2019
Author(s)
岡村和俊, 北本江梨奈, 日置一仁, 濱田栄樹, 北村亮二, 山内恵利香, 筑井徹, 加美由紀子, 吉浦 一紀
Organizer
日本歯科放射線学会 第38回関西・九州合同地方会
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