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Longitudinal study of factors affecting salivary Substance P decline in independent elderly people

Research Project

Project/Area Number 18K17304
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 57080:Social dentistry-related
Research InstitutionMatsumoto Dental University (2019-2020)
Aichi Gakuin University (2018)

Principal Investigator

Dewake Nanae  松本歯科大学, 歯学部, 助教 (40747268)

Project Period (FY) 2018-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2020: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2019: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2018: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Keywords自立高齢者 / Substance P / 嚥下機能 / 骨格筋量 / 介護予防 / 口腔機能 / 臼歯部咬合 / 現在歯数 / 高齢者
Outline of Final Research Achievements

Recently, research has been conducted on how oral function and swallowing function of the elderly people affect general health. The purpose of this study was to clarify the relationship between swallowing function and number of present teeth, occlusal state, and skeletal muscle index in the elderly people living in the community. The number of elderly people who participated in the long-term care prevention project was 236 (88 men: average age 75.9 ± 7.4 years, 148 women: 77.6 ± 6.5 years).
This result suggests that loss of occlusal support in the molar may be associated with decreased swallowing function in community-dwelling elderly women. In addition, it may suggests that the independent elderly maintain a constant Substance P.

Academic Significance and Societal Importance of the Research Achievements

本研究では、口腔機能、Substance P(SP)を用いた嚥下機能の評価および全身およびとの関連について明らかにすることで、高齢者の唾液中SP濃度計測による簡便な嚥下機能評価について検討した。自立高齢者において、SP値と反復唾液嚥下テストの関連については有意な傾向を示した。また、自立高齢者は入院患者や要介護者と比較し、一定のSP値を維持している可能性があり、今後は対象に自立高齢者以外に要介護状態の高齢者を加え比較し検討を続けていく必要がある。

Report

(4 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (2 results)

All 2019

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 2 results)

  • [Journal Article] Posterior occluding pairs of teeth or dentures and 1‐year mortality in nursing home residents in Japan2019

    • Author(s)
      Dewake Nanae、Hashimoto Hiroko、Nonoyama Toshiya、Nonoyama Kaoru、Shimazaki Yoshihiro
    • Journal Title

      Journal of Oral Rehabilitation

      Volume: 47 Issue: 2 Pages: 204-211

    • DOI

      10.1111/joor.12883

    • Related Report
      2020 Annual Research Report 2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 地域在住高齢者における反復唾液嚥下テストと臼歯部の咬合状態および骨格筋指数との関連について2019

    • Author(s)
      出分菜々衣,武藤 昭紀,野々山順也,橋本 周子,齊藤 瑞季,嶋﨑 義浩
    • Journal Title

      日本口腔衛生学会会誌

      Volume: 69

    • NAID

      130007689485

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access

URL: 

Published: 2018-04-23   Modified: 2022-01-27  

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