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Early detection of dementia using evaluation tool for oral psychosomatic disorders

Research Project

Project/Area Number 18K17306
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 57080:Social dentistry-related
Research InstitutionFukuoka Dental College

Principal Investigator

Umezaki Yojiro  福岡歯科大学, 口腔歯学部, 准教授 (20778336)

Project Period (FY) 2018-04-01 – 2021-03-31
Project Status Completed (Fiscal Year 2020)
Budget Amount *help
¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2018: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords歯科心身症 / 認知症 / 早期発見 / 口腔異常感症 / 咬合異常感 / 口腔セネストパチー / Oral DRS / 舌痛症
Outline of Final Research Achievements

Some researchers reported that oral psychosomatic symptoms developed as a prodrome symptom of dementia. In this study, we used evaluation tool of oral psychosomatic disorders for early detection of dementia.
In detail, we conducted two studies, i.e. functional brain imaging study and clinical statistical study. In the functional brain imaging study, we found a unique pattern of cerebral blood flow in the patients with phantom bite syndrome, a kind of oral psychosomatic disorders. The pattern was different from that of dementia. In the clinical statistical study, 2% of outpatients with oral psychosomatic disorders had a history of dementia. We could detect dementia in the early stage using evaluation tool for oral psychosomatic disorders.
Using evaluation tool for oral psychosomatic disorders might contribute the early detection of dementia.

Academic Significance and Societal Importance of the Research Achievements

認知症と歯科心身症は全く異なる病態ではあるが、認知症の前駆症状として口腔の不定愁訴が出現し得ることを報告した。幻覚や嗅覚の異常などが認知症の早期発見につながることが以前から指摘されていたが、口腔内感覚の変化も早期発見に有用な情報であることが示唆された。
歯科心身症に用いられる問診ツールを一般歯科にも応用することで、より多くの場での認知症のスクリーニングが可能になると期待できる。超高齢社会を迎え、認知症が社会的課題となっている本邦において、歯科からも積極的に認知症を発見することは患者さんやその家族だけでなく、医療経済的にも有益であると思われる。

Report

(4 results)
  • 2020 Annual Research Report   Final Research Report ( PDF )
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (9 results)

All 2020 2019 2018

All Journal Article (4 results) (of which Peer Reviewed: 4 results,  Open Access: 3 results) Presentation (5 results) (of which Invited: 1 results)

  • [Journal Article] 高齢者歯科外来における2017、2018年度の歯科心身症患者153名の臨床統計的検討2020

    • Author(s)
      梅崎 陽二朗, 金光 芳郎, 澤本 良子, 豊福 明, 内藤 徹
    • Journal Title

      日本歯科心身医学会雑誌

      Volume: 35 Pages: 13-19

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Change of Cerebral Blood Flow After a Successful Pharmacological Treatment of Phantom Bite Syndrome: A Case Report.2019

    • Author(s)
      Umezaki Y, Tu TTH, Toriihara A, Sato Y, Naito T, Toyofuku A.
    • Journal Title

      Clin Neuropharmacol

      Volume: 42 Issue: 2 Pages: 49-51

    • DOI

      10.1097/wnf.0000000000000328

    • Related Report
      2019 Research-status Report 2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Comorbid depressive disorders and left‐side dominant occlusal discomfort in patients with phantom bite syndrome2019

    • Author(s)
      Shinohara Yukiko、Umezaki Yojiro、Minami Ichiro、Watanabe Motoko、Miura Anna、Mikutsuki Lou、Kawasaki Kaoru、Sugawara Shiori、Trang Tu Thi Hyen、Suga Takayuki、Watanabe Takeshi、Yoshikawa Tatsuya、Takenoshita Miho、Motomura Haruhiko、Toyofuku Akira
    • Journal Title

      Journal of Oral Rehabilitation

      Volume: 47 Issue: 1 Pages: 36-41

    • DOI

      10.1111/joor.12872

    • NAID

      120007147660

    • Related Report
      2019 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Clinical characteristics and course of oral somatic delusions: a retrospective chart review of 606 cases in 5 years2018

    • Author(s)
      Umezaki Yojiro、Miura Anna、Shinohara Yukiko、Mikuzuki Lou、Sugawara Shiori、Kawasaki Kaoru、Tu Trang、Watanabe Takeshi、Suga Takayuki、Watanabe Motoko、Takenoshita Miho、Yoshikawa Tatsuya、Uezato Akihito、Nishikawa Toru、Hoshiko Ken、Naito Toru、Motomura Haruhiko、Toyofuku Akira
    • Journal Title

      Neuropsychiatric Disease and Treatment

      Volume: Volume 14 Pages: 2057-2065

    • DOI

      10.2147/ndt.s167527

    • NAID

      120007147657

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 歯科心身症へのアプローチ ~はじめの一歩~ 地域医療における歯科心身症への対応2020

    • Author(s)
      梅崎陽二朗
    • Organizer
      総合歯科学会
    • Related Report
      2020 Annual Research Report
    • Invited
  • [Presentation] 内科通院中の高齢者における脳萎縮と口腔指標との関連2019

    • Author(s)
      梅崎陽二朗,江頭留依,水谷慎介,山口真広,藤田拓,玉井恵子,牧野路子,内藤 徹
    • Organizer
      第30回日本老年歯科医学会学術大会
    • Related Report
      2019 Research-status Report
  • [Presentation] 福岡歯科大学高齢者歯科学分野における歯科心身症患者の実態2019

    • Author(s)
      梅崎陽二朗、江頭留依、吉田瑞姫,山口真広、藤田拓、玉井恵子、牧野路子、内藤徹
    • Organizer
      第46回福岡歯科大学学会総会
    • Related Report
      2019 Research-status Report
  • [Presentation] Relationship between cerebral atrophy and present teeth in elderly individuals.2019

    • Author(s)
      Rui Egashira, Yojiro Umezaki, Shinsuke Mizutani, Toyoshi Obata, Toru Naito
    • Organizer
      第97回IADR
    • Related Report
      2019 Research-status Report
  • [Presentation] 福岡歯科大学高齢者歯科学分野における歯科心身症患者の実態2018

    • Author(s)
      梅﨑陽二朗、内藤徹
    • Organizer
      日本顎関節学会総会・学術大会 日本口腔顔面痛学会学術大会 日本歯科心身医学会総会・学術大会
    • Related Report
      2018 Research-status Report

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Published: 2018-04-23   Modified: 2022-01-27  

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