| Project/Area Number |
18K17484
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 58060:Clinical nursing-related
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| Research Institution | Kyoto University |
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Principal Investigator |
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| Project Period (FY) |
2018-04-01 – 2023-03-31
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| Project Status |
Completed (Fiscal Year 2022)
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| Budget Amount *help |
¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2019: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2018: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
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| Keywords | 食行動 / 肥満 / 内臓脂肪 / 遅延報酬割引 / 報酬系 / 衝動性 / 遅延割引報酬 / 潜在連合テスト |
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| Outline of Final Research Achievements |
Many patients with obesity and type 2 diabetes are considered to have a dependence on high-calorie and high-fat diets, which is thought to be caused by heightened reactivity of the brain's reward system. However, there is no established system to evaluate the reaction of the brain's reward system as behavior in humans. Therefore, this study aimed to evaluate impulsivity in eating behavior using delay discounting and examine the relationship between visceral fat accumulation and impulsivity in eating behavior in obese individuals.
As a result, there was no significant correlation between the newly developed delay discounting measurement method and visceral fat accumulation. However, a tendency for correlation was observed in subjects with visceral fat accumulation despite having a normal BMI.
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| Academic Significance and Societal Importance of the Research Achievements |
今回作成した遅延報酬割引の測定法と内臓脂肪量に有意な関連は見られなかった。しかし、正常BMIであるにも関わらず、内臓脂肪が蓄積している対象者では関連がある傾向が見られた。このことから、今回作成した遅延報酬割引の測定法は、いわゆるサルコペニア肥満のような病態における食行動の評価に活かせる可能性が示唆された。
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