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The effect of microelectric stimulation of the skin aiming at painless injection for children with hemophilia

Research Project

Project/Area Number 18K17594
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 58070:Lifelong developmental nursing-related
Research InstitutionKyushu University (2021)
Mukogawa Women's University (2018-2020)

Principal Investigator

Ueki Shingo  九州大学, 医学研究院, 准教授 (10779218)

Project Period (FY) 2018-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2020: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2019: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2018: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords痛み / 注射 / 電気刺激 / 振動刺激 / 小児 / 子ども / 穿刺 / ゲートコントロール理論 / 疼痛緩和 / システマティックレビュー / 血友病
Outline of Final Research Achievements

A total of 4144 pain stimuli was evaluated under electrical stimulation. In any setting, the NRS score was 8 to 10 points, and no effective settings were found to reduce pain. Next, we conducted a systematic review of focusing on the effect of reducing pain by vibratory stimulation. Vibratory stimulation was a significant pain reduction effect, but the reliability of this result was doubtful because of poor in included researches' methodological quality. 3) Randomized controlled trial for children was conducted, but the effect of vibratory stimulation in reducing pain for vaccination was not significant. Therefore, it was considered that the effect of reducing pain was doubtful even with vibratory stimulation.

Academic Significance and Societal Importance of the Research Achievements

本研究は、痛み刺激後に触覚刺激を行うことによる痛み軽減というゲートコントロール理論を応用して、触覚刺激を行いながら痛み刺激を行うことで痛みが軽減するという仮説の下、研究を実施した。しかし、パイロット研究やシステマティックレビュー、臨床研究においてもその仮説を検証することができなかった。しかし、臨床研究時におけるアンケートによると、注射の対象である子どもの親は本研究課題に大変興味を持っていることがわかり、侵襲の少ない介入によって解決すべき痛みの軽減がわずかにでも測れるのであれば実施してほしいという声が聞かれた。このことからも、有効な痛み軽減の介入方法の模索を行っていく必要がある。

Report

(5 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (3 results)

All 2021 2019 2018

All Journal Article (2 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 2 results) Presentation (1 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] The effectiveness of vibratory stimulation in reducing pain in children receiving vaccine injection: A randomized controlled trial.2021

    • Author(s)
      Ueki S, Matsunaka E, Takao K, Kitao M, Fukui M, Fujita Y
    • Journal Title

      Vaccine

      Volume: 39 Issue: 15 Pages: 2080-2087

    • DOI

      10.1016/j.vaccine.2021.03.013

    • Related Report
      2021 Annual Research Report 2020 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Effectiveness of vibratory stimulation on needle-related procedural pain in children: a systematic review.2019

    • Author(s)
      Ueki S, Yamagami Y, Makimoto K.
    • Journal Title

      JBI Database System Rev Implement Rep.

      Volume: 印刷中 Issue: 7 Pages: 1428-1463

    • DOI

      10.11124/jbisrir-2017-003890

    • Related Report
      2019 Research-status Report 2018 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] Effectiveness of vibratory stimulation on needle-related procedural pain in children: a systematic review2018

    • Author(s)
      Ueki S, Yamagami Y, Makimoto K.
    • Organizer
      10th Biennial Joanna Briggs Institute Colloquium 2018
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research

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Published: 2018-04-23   Modified: 2023-01-30  

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