| Project/Area Number |
18K17677
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 59010:Rehabilitation science-related
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| Research Institution | Sapporo Medical University |
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Principal Investigator |
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| Project Period (FY) |
2018-04-01 – 2023-03-31
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| Project Status |
Completed (Fiscal Year 2022)
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| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2021: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2020: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2019: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2018: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 栄養状態 / 摂取エネルギー量 / 高齢者 / 心不全 / 心臓リハビリテーション / サルコペニア / フレイル / 骨粗鬆症 / 体組成 / 骨格筋量 / 健康寿命 / 慢性心不全 / 生活機能 / 併存疾患 |
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| Outline of Final Research Achievements |
This research investigated the relationship between the nutritional status and decline in daily living abilities of elderly heart failure patients, and the overall mortality risk through a multi-center, prospective observational study. Despite the inability to carry out the research plan due to the novel coronavirus pandemic, a retrospective review of our own facility's data revealed that the nutritional status and energy intake at the start of cardiac rehabilitation were strongly associated with self-reliance in daily life and overall mortality risk. Furthermore, in the case of elderly heart failure patients in the hospital, it was found that the level of daily living functions at discharge (as measured by the Barthel Index score) was strongly related to the onset of total mortality, and that an increase in the total mortality risk began with a slight decline in daily living functions (discharge Barthel Index <85 points).
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| Academic Significance and Societal Importance of the Research Achievements |
多種多様な臨床像を呈する高齢心不全の心臓リハビリテーションの効果の予測に加え，高齢心不全の心臓リハビリテーションをより効果的に進めるための短期的・長期的な栄養介入の方法の確立に繋がりうる．
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