The impact of poor nutritional status on functional outcome in elderly heart failure: a multicenter observational study

• Project/Area Number: 18K17677
• Research Category: Grant-in-Aid for Early-Career Scientists
• Allocation Type: Multi-year Fund
• Review Section: Basic Section 59010:Rehabilitation science-related
• Research Institution: Sapporo Medical University
• Principal Investigator: Katano Satoshi 札幌医科大学, 医学部, 研究員 (50438040)
• Project Period (FY): 2018-04-01 – 2023-03-31
• Project Status: Completed (Fiscal Year 2022)
• Budget Amount: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2021: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2020: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2019: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2018: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
• Keywords: 栄養状態 / 摂取エネルギー量 / 高齢者 / 心不全 / 心臓リハビリテーション / サルコペニア / フレイル / 骨粗鬆症 / 体組成 / 骨格筋量 / 健康寿命 / 慢性心不全 / 生活機能 / 併存疾患

Outline of Final Research Achievements

This research investigated the relationship between the nutritional status and decline in daily living abilities of elderly heart failure patients, and the overall mortality risk through a multi-center, prospective observational study. Despite the inability to carry out the research plan due to the novel coronavirus pandemic, a retrospective review of our own facility's data revealed that the nutritional status and energy intake at the start of cardiac rehabilitation were strongly associated with self-reliance in daily life and overall mortality risk. Furthermore, in the case of elderly heart failure patients in the hospital, it was found that the level of daily living functions at discharge (as measured by the Barthel Index score) was strongly related to the onset of total mortality, and that an increase in the total mortality risk began with a slight decline in daily living functions (discharge Barthel Index <85 points).

Academic Significance and Societal Importance of the Research Achievements

多種多様な臨床像を呈する高齢心不全の心臓リハビリテーションの効果の予測に加え，高齢心不全の心臓リハビリテーションをより効果的に進めるための短期的・長期的な栄養介入の方法の確立に繋がりうる．

Research Products

• [Journal Article] 特集 医療現場におけるサルコペニア･フレイル 循環器疾患領域におけるサルコペニア･フレイル (2022)
  • Author(s): 片野 唆敏、長岡 凌平、沼澤 瞭
  • Journal Title: 理学療法ジャーナル Volume: 56 Issue: 6 Pages: 650-656
  • DOI: 10.11477/mf.1551202695
  • ISSN: 0915-0552, 1882-1359
  • Year and Date: 2022-06-15
• [Journal Article] Anthropometric parameters‐derived estimation of muscle mass predicts all‐cause mortality in heart failure patients (2022)
  • Author(s): Katano Satoshi、Honma Suguru、Nagaoka Ryohei、Numazawa Ryo、Yamano Kotaro、Fujisawa Yusuke、Ohori Katsuhiko、Kouzu Hidemichi、Hashimoto Akiyoshi、Katayose Masaki、Yano Toshiyuki
  • Journal Title: ESC Heart Failure Volume: 9 Issue: 6 Pages: 4358-4365
  • DOI: 10.1002/ehf2.14121
  • Peer Reviewed / Open Access
• [Journal Article] Loss of perceived social role, an index of social frailty, is an independent predictor of future adverse events in hospitalized patients with heart failure (2022)
  • Author(s): Watanabe Ayako、Katano Satoshi、Yano Toshiyuki、Nagaoka Ryohei、Numazawa Ryo、Honma Suguru、Yamano Kotaro、Fujisawa Yusuke、Ohori Katsuhiko、Kouzu Hidemichi、Ishigo Tomoyuki、Katayose Masaki、Hashimoto Akiyoshi、Furuhashi Masato
  • Journal Title: Frontiers in Cardiovascular Medicine Volume: 9 Pages: 1051570-1051570
  • DOI: 10.3389/fcvm.2022.1051570
  • Peer Reviewed / Open Access
• [Journal Article] Elevated circulating level of β-aminoisobutyric acid (BAIBA) in heart failure patients with type 2 diabetes receiving sodium-glucose cotransporter 2 inhibitors (2022)
  • Author(s): Katano Satoshi、Yano Toshiyuki、Kouzu Hidemichi、Nagaoka Ryohei、Numazawa Ryo、Yamano Kotaro、Fujisawa Yusuke、Ohori Katsuhiko、Nagano Nobutaka、Fujito Takefumi、Nishikawa Ryo、Ohwada Wataru、Katayose Masaki、Sato Tatsuya、Kuno Atsushi、Furuhashi Masato
  • Journal Title: Cardiovascular Diabetology Volume: 21 Issue: 1 Pages: 285-285
  • DOI: 10.1186/s12933-022-01727-x
  • Peer Reviewed / Open Access
• [Journal Article] Barthel Index Score Predicts Mortality in Elderly Heart Failure ― A Goal of Comprehensive Cardiac Rehabilitation ― (2021)
  • Author(s): Katano Satoshi、Yano Toshiyuki、Ohori Katsuhiko、Kouzu Hidemichi、Nagaoka Ryohei、Honma Suguru、Shimomura Kanako、Inoue Takuya、Takamura Yuhei、Ishigo Tomoyuki、Watanabe Ayako、Koyama Masayuki、Nagano Nobutaka、Fujito Takefumi、Nishikawa Ryo、Ohwada Wataru、Hashimoto Akiyoshi、et al.
  • Journal Title: Circulation Journal Volume: 86 Issue: 1 Pages: 70-78
  • DOI: 10.1253/circj.CJ-21-0584
  • NAID: 130008132631
  • ISSN: 1346-9843, 1347-4820
  • Year and Date: 2021-12-24
  • Peer Reviewed / Open Access
• [Journal Article] Does renin‐angiotensin system inhibition have impacts on muscle mass and bone mineral density in heart failure patients? (2021)
  • Author(s): Katano Satoshi、Yano Toshiyuki、Shimizu Masaki、Ohori Katsuhiko、Kouzu Hidemichi、Koyama Masayuki、Nagaoka Ryohei、Inoue Takuya、Takamura Yuhei、Ishigo Tomoyuki、Takashima Hiroyuki、Katayose Masaki、Ohnishi Hirofumi、Miura Tetsuji
  • Journal Title: ESC Heart Failure Volume: 8 Issue: 4 Pages: 2617-2624
  • DOI: 10.1002/ehf2.13430
  • Peer Reviewed / Open Access
• [Journal Article] Energy intake during hospital stay predicts all-cause mortality after discharge independently of nutritional status in elderly heart failure patients (2021)
  • Author(s): Katano Satoshi、Yano Toshiyuki、Kouzu Hidemichi、Ohori Katsuhiko、Shimomura Kanako、Honma Suguru、Nagaoka Ryohei、Inoue Takuya、Takamura Yuhei、Ishigo Tomoyuki、Watanabe Ayako、Koyama Masayuki、Nagano Nobutaka、Fujito Takefumi、Nishikawa Ryo、Ohwada Wataru、Hashimoto Akiyoshi、Katayose Masaki、Miura Tetsuji
  • Journal Title: Clinical Research in Cardiology Volume: - Issue: 8 Pages: 1202-1220
  • DOI: 10.1007/s00392-020-01774-y
  • Peer Reviewed / Open Access
• [Journal Article] High percent body fat mass predicts lower risk of cardiac events in patients with heart failure: an explanation of the obesity paradox (2021)
  • Author(s): Ohori Katsuhiko、Yano Toshiyuki、Katano Satoshi、Kouzu Hidemichi、Honma Suguru、Shimomura Kanako、Inoue Takuya、Takamura Yuhei、Nagaoka Ryohei、Koyama Masayuki、Nagano Nobutaka、Fujito Takefumi、Nishikawa Ryo、Ishigo Tomoyuki、Watanabe Ayako、Hashimoto Akiyoshi、Miura Tetsuji
  • Journal Title: BMC Geriatrics Volume: 21 Issue: 1
  • DOI: 10.1186/s12877-020-01950-9
  • Peer Reviewed
• [Journal Article] Clinical Risk Factors and Prognostic Impact of Osteoporosis in Patients With Chronic Heart Failure (2020)
  • Author(s): Katano S, Yano T, Tsukada T, Kouzu H, Honma S, Inoue T, Takamura Y, Nagaoka R, Ishigo T, Watanabe A, Ohori K, Koyama M, Nagano N, Fujito T, Nishikawa R, Takashima H, Hashimoto A, Katayose M, Miura T.
  • Journal Title: Circulation Journal Volume: 84 Issue: 12 Pages: 2224-2234
  • DOI: 10.1253/circj.CJ-20-0593
  • NAID: 130007942506
  • ISSN: 1346-9843, 1347-4820
  • Year and Date: 2020-11-25
  • Peer Reviewed / Open Access
• [Journal Article] Overestimation of glomerular filtration rate by creatinine-based equation in heart failure patients is predicted by a novel scoring system (2020)
  • Author(s): Ishigo T, Katano S, Yano T, Kouzu H, Ohori K, Nakata H, Nonoyama M, Inoue T, Takamura Y, Nagaoka R, Kondo F, Nakano K, Takada R, Kitagawa M, Kimyo T, Miura T.
  • Journal Title: Geriatr Gerontol Int Volume: 20 Issue: 8 Pages: 752-758
  • DOI: 10.1111/ggi.13959
  • Peer Reviewed
• [Journal Article] Reply to the comments on "Utility of the sarcopenia index for assessment of muscle mass and nutritional status in patients with chronic heart failure: Comparison with anthropometric parameters" (2020)
  • Author(s): Abe K, Yano T, Katano S, Ohori K, Ishigo T, Kouzu H, Moniwa N, Miura T.
  • Journal Title: Geriatr Gerontol Int Volume: 20 Issue: 10 Pages: 998-999
  • DOI: 10.1111/ggi.14001
  • Peer Reviewed
• [Journal Article] Distinct determinants of muscle wasting in nonobese heart failure patients with and without type 2 diabetes mellitus (2020)
  • Author(s): Yano Toshiyuki、Katano Satoshi、Kouzu Hidemichi、Nagaoka Ryohei、Inoue Takuya、Takamura Yuhei、Ishigo Tomoyuki、Watanabe Ayako、Ohori Katsuhiko、Koyama Masayuki、Nagano Nobutaka、Fujito Takefumi、Nishikawa Ryo、Hashimoto Akiyoshi、Miura Tetsuji
  • Journal Title: Journal of Diabetes Volume: 13 Issue: 1 Pages: 7-18
  • DOI: 10.1111/1753-0407.13090
  • Peer Reviewed
• [Journal Article] Independent link between peripheral artery disease and muscle wasting in patients with heart failure (2020)
  • Author(s): Ohori K, Yano T, Katano S, Kouzu H, Inoue T, Takamura Y, Nagaoka R, Ishigo T, Koyama M, Nagano N, Fujito T, Nishikawa R, Miura T.
  • Journal Title: ESC Heart Fail (supported by 19K08544) Volume: 7 Issue: 5 Pages: 3252-3256
  • DOI: 10.1002/ehf2.12951
  • Peer Reviewed / Open Access
• [Journal Article] Novel prediction equation for appendicular skeletal muscle mass estimation in patients with heart failure: Potential application in daily clinical practice (2020)
  • Author(s): Katano Satoshi、Yano Toshiyuki、Ohori Katsuhiko、Nagano Nobutaka、Honma Suguru、Shimomura Kanako、Ishigo Tomoyuki、Watanabe Ayako、Honma Remi、Fujito Takefumi、Koyama Masayuki、Kouzu Hidemichi、Hashimoto Akiyoshi、Katayose Masaki、Miura Tetsuji
  • Journal Title: European Journal of Preventive Cardiology Volume: - Issue: 9 Pages: e18-e21
  • DOI: 10.1177/2047487320904236
  • Peer Reviewed
• [Journal Article] Utility of the sarcopenia index for assessment of muscle mass and nutritional status in patients with chronic heart failure: Comparison with anthropometric parameters. (2020)
  • Author(s): Abe K, Yano T, Katano S, Ohori H, Ishigo T, Moniwa N, Miura T.
  • Journal Title: Geriatr Gerontol Int Volume: 20 Issue: 4 Pages: 388-389
  • DOI: 10.1111/ggi.13876
  • Peer Reviewed
• [Journal Article] Utility and safety of tocilizumab in Takayasu arteritis with severe heart failure and muscle wasting. (2019)
  • Author(s): Yano T, Osanami A, Shimizu M, Katano S, Nagano N, Kouzu H, Koyama M, Muranaka A, Harada R, Doi H, Kawaharada N, Miura T.
  • Journal Title: ESC Heart Fail Volume: 6 Issue: 4 Pages: 894-894
  • DOI: 10.1002/ehf2.12487
  • Peer Reviewed / Open Access
• [Journal Article] Nutritional Status and Energy Intake as Predictors of Functional Status After Cardiac Rehabilitation in Elderly Inpatients With Heart Failure ― A Retrospective Cohort Study ― (2018)
  • Author(s): Katano Satoshi、Hashimoto Akiyoshi、Ohori Katsuhiko、Watanabe Ayako、Honma Remi、Yanase Rimi、Ishigo Tomoyuki、Fujito Takefumi、Ohnishi Hirofumi、Tsuchihashi Kazufumi、Ishiai Sumio、Miura Tetsuji
  • Journal Title: Circulation Journal Volume: 82 Issue: 6 Pages: 1584-1591
  • DOI: 10.1253/circj.CJ-17-1202
  • NAID: 130006744250
  • ISSN: 1346-9843, 1347-4820
  • Year and Date: 2018-05-25
  • Peer Reviewed / Open Access
• [Presentation] Novel equation for skeletal muscle mass estimation is useful for predicting mortality in patients with heart failure (2022)
  • Author(s): Honma S., Katano S., Nagaoka R., Numazawa R., Kouzu H., Ohori K., Nishikawa R., Ohwada W., Nagano N., Koyama M., Katayose M., Kobayashi C., Yoshioka N., Hashimoto A., Yano T.
  • Organizer: ESC Preventive Cardiology 2022
  • Int'l Joint Research
• [Presentation] Decreased 25-hydroxyvitamin D levels are associated with sarcopenia in patients with chronic heart failure (2022)
  • Author(s): Nagaoka R., Katano S., Numazawa R., Kouzu H., Ohori K., Honma S., Kamoda T., Sato K., Nishikawa R., Ohwada W., Nagano N., Koyama M., Katayose M., Hashimoto A., Yano T.
  • Organizer: ESC Preventive Cardiology 2022
  • Int'l Joint Research
• [Presentation] Coexistence of sarcopenia and osteoporosis in patients with heart failure: prevalence and association with functional status (2022)
  • Author(s): Numazawa R., Katano S., Nagaoka R., Honma S., Ohori K., Kouzu H., Watanbe A., Fujito T., Nishikawa R., Ohwada W., Nagano N., Koyama M., Katayose M., Hashimoto A., Yano T.
  • Organizer: ESC congress 2022
  • Int'l Joint Research
• [Presentation] Loss of social role awareness, a subdomain of social frailty, is an independent predictor of future adverse events in hospitalized older patients with heart failure (2022)
  • Author(s): Katano S., Watanbe A., Nagaoka R., Numazawa R., Honma S., Ohori K., Kouzu H., Fujito T., Nishikawa R., Ohwada W., Nagano N., Koyama M., Katayose M., Hashimoto A., Yano T.
  • Organizer: ESC congress 2022
  • Int'l Joint Research
• [Presentation] Is activation of the renin-angiotensin system associated with lower skeletal muscle mass in heart failure patients? (2022)
  • Author(s): Numazawa R., Katano S., Yamashita T., Nagaoka R., Yamano K., Fujisawa Y., Ohori K., Kouzu H., Fujito T., Nishikawa R., Ohwada W., Nagano N., Koyama M., Hashimoto A., Yano T.
  • Organizer: Heart Failure Seoul 2022
  • Int'l Joint Research
• [Presentation] Implementation of a novel conference sheet into multidisciplinary team approach improves clinical outcomes in older heart failure patients (2022)
  • Author(s): Katano S., Watanabe A., Nagaoka R., Numazawa R., Fujisawa Y., Yamano K., Ishigo T., Ohori K., Nishikawa R., Ohwada W., Nagano N., Koyama M., Kouzu H., Hashimoto A., Yano T.
  • Organizer: Heart Failure Seoul 2022
  • Int'l Joint Research
• [Presentation] シンポジウム：サルコペニア合併心不全における骨粗鬆症の併存率ならびに生活機能への影響 (2022)
  • Author(s): 片野唆敏，長岡凌平，矢野俊之，沼澤 瞭，大堀克彦，神津英至，本間 傑，渡辺絢子，藤戸健史，西川 諒，大和田渉，永野伸卓，橋本暁佳，片寄正樹，三浦哲嗣
  • Organizer: 第 86 回日本循環器学会学術集会
  • Int'l Joint Research
• [Presentation] サルコペニアを合併する心不全患者の骨密度と性差の関連 (2022)
  • Author(s): 沼澤 瞭，片野唆敏，長岡凌平，神津英至，大堀克彦，渡辺絢子，藤戸健史，西川 諒，大和田渉，永野伸卓，小山雅之，橋本暁佳，片寄正樹，矢野俊之
  • Organizer: 第 86 回日本循環器学会学術集会
• [Presentation] 高齢心不全における社会的フレイルとその構成要素が予後に及ぼす影響 (2022)
  • Author(s): 渡辺絢子，片野唆敏，柳瀬理美，永井早紀，米川 葵，藤田梨恵，長岡凌平，沼澤 瞭，大堀克彦，神津英至，藤戸健史，西川 諒，大和田渉，永野伸卓，小山雅之，橋本暁佳，矢野俊之
  • Organizer: 第 86 回日本循環器学会学術集会
• [Presentation] Impacts of proton pump inhibitors on body composition and clinical outcome in patients with heart failure (2022)
  • Author(s): Ohori K., Katano S., Nagaoka R., Numazawa R., Kouzu H., Koyama M., Nagano N., Fujito T., Nishikawa R., Owada W., Yano T.
  • Organizer: 第 86 回日本循環器学会学術集会
• [Presentation] Plasma 3-methylhistidine predicts the impact of renin-angiotensin system inhibition on skeletal muscle preservation in heart failure patients (2022)
  • Author(s): Kouzu H., Katano S., Ohori K., Nagaoka R., Numazawa R., Koyama M., Nagano N., Fujito T., Ohwada W., Nishikawa R., Yano T.
  • Organizer: 第 86 回日本循環器学会学術集会
• [Presentation] 慢性心不全におけるレニンアンジオテンシン系活性化と骨格筋量の関連 (2022)
  • Author(s): 沼澤 瞭，片野唆敏，長岡凌平，山下智久，矢野俊之
  • Organizer: 第 10 回臨床高血圧フォーラム
• [Presentation] 心肺運動負荷試験指標を用いた肺高血圧症予測スコアの開発と有効性の検討 (2022)
  • Author(s): 沼澤 瞭，片野唆敏，長岡凌平，渡辺絢子，米川 葵，中島直美，石郷友之，小山雅之，矢野俊之，橋本暁佳
  • Organizer: 第 7 回日本肺高血圧・肺循環学会学術集会
• [Presentation] 心不全患者の骨密度は推定式から予測化能か？：骨密度の新規推定式の開発と推定精度の検証 (2022)
  • Author(s): 沼澤 瞭，片野唆敏，長岡凌平，本間 傑，藤澤佑輔，山埜光太郎，大堀克彦，片寄正樹，矢野俊之，橋本暁佳
  • Organizer: 第 6 回日本循環器理学療法学会学術大会
• [Presentation] 循環器理学療法プログラムの最適解を探る：栄養からみた筋消耗・サルコペニアの治療戦略 (2022)
  • Author(s): 片野唆敏，長岡凌平，沼澤 瞭，山埜光太郎，藤澤佑輔，本間 傑
  • Organizer: 第 6 回日本循環器理学療法学会学術大会
• [Presentation] 心不全患者における骨粗鬆症予測スコアの開発と精度の検証 (2022)
  • Author(s): 沼澤 瞭，片野唆敏，長岡凌平，藤澤佑輔，山埜光太郎，大堀克彦，渡辺絢子，石郷友之，西川 諒，大和田渉，永野伸卓，小山雅之，神津英至，橋本暁佳，矢野俊之
  • Organizer: 第 26 回日本心不全学会学術集会
• [Presentation] 高齢心不全診療における多職種連携ツール：患者特性を可視化した心不全カンファレンスシートの開発 (2022)
  • Author(s): 心不全患者における骨粗鬆症予測スコアの開発と精度の検証
  • Organizer: 第 26 回日本心不全学会学術集会
• [Presentation] 第 27 回日本心臓リハビリテーション学会学術集会 (2021)
  • Author(s): 片野唆敏，矢野俊之，長岡凌平，本間 傑，大堀克彦，神津英至，石郷友之，渡辺絢子，永野伸卓，藤戸健史，&#11972;川 諒，大和田渉，橋本暁佳，片寄正樹，石合純夫，三浦哲嗣
  • Organizer: 第 27 回日本心臓リハビリテーション学会学術集会
• [Presentation] Barthel Index score predicts mortality in elderly heart failure: a goal of comprehensive cardiac rehabilitation (2021)
  • Author(s): Katano S., Yano T., Ohori K., Kouzu H., Nagaoka R., Honma S., Shimomura K., Numazawa R., Koyama M., Nagano N., Fujito T., Nishikawa R., Hashimoto A., Katayose M., Miura T.
  • Organizer: ESC congress 2021
  • Int'l Joint Research
• [Presentation] 心不全患者におけるビタミン D の低下はサルコペニアのリスク因子である (2021)
  • Author(s): 長岡凌平，片野唆敏，矢野俊之，本間 傑，沼澤 瞭，神津英至，大堀克彦，片寄正樹，橋本暁佳
  • Organizer: 第 5 回日本循環器理学療法学会学術大会
• [Presentation] 形態指標に基づく新たな四肢骨格筋量推定式は心不全患者の予後を良好に予測する (2021)
  • Author(s): 本間 傑，片野唆敏，矢野俊之，長岡凌平，沼澤 瞭，神津英至，大堀克彦，片寄正樹， 善岡信博，橋本暁佳
  • Organizer: 第 5 回日本循環器理学療法学会学術大会
• [Presentation] プロトンポンプ阻害薬が心不全患者の骨格筋量に与える影響 (2021)
  • Author(s): 大堀克彦，矢野俊之，片野唆敏，長岡凌平，神津英至，永野伸卓，藤戸健史，&#11972;川 諒，大和田渉，土橋和文
  • Organizer: 第 69 回日本心臓病学会学術集会
• [Presentation] オステオサルコペニアの合併は心不全患者の予後不良と関連する (2021)
  • Author(s): 長岡凌平，片野唆敏，矢野俊之，沼澤 瞭，神津英至，本間 傑，渡辺絢子，石郷友之，大堀克彦，鴨田 樹，片寄正樹，橋本暁佳
  • Organizer: 第 6 回日本心臓リハビリテーション学会北海道支部地方会
• [Presentation] 社会的フレイルの合併は高齢心不全の予後予測因子か? (2021)
  • Author(s): 渡辺絢子，片野唆敏，柳瀬理美，藤田梨恵，長岡凌平，沼澤 瞭，大堀克彦，神津英至，藤戸健史，&#11972;川 諒，大和田渉，永野伸卓，小山雅之，矢野俊之，橋本暁佳
  • Organizer: 第 6 回日本心臓リハビリテーション学会北海道支部地方会
• [Presentation] 心不全患者におけるサルコペニアは骨粗鬆症のリスク因子である (2020)
  • Author(s): 長岡凌平，片野唆敏，矢野俊之，井上拓也，高村悠平，本間 傑，渡辺絢子，石郷友之，本間レミ，藤戸健史，西川 諒，永野伸卓，大堀克彦，神津英至，橋本暁佳，片寄正樹，三浦哲嗣
  • Organizer: 第 26 回日本心臓リハビリテーション学会学術集会
• [Presentation] 日本語版 SARC-F は心不全患者のサルコペニアの診断に有用か？ (2020)
  • Author(s): 高村悠平，片野唆敏，矢野俊之，本間 傑，井上拓也，長岡凌平，渡辺絢子，石郷友之，本間レミ，藤戸健史，西川 諒，永野伸卓，大堀克彦，神津英至，橋本暁佳，片寄正樹，三浦哲嗣
  • Organizer: 第 26 回日本心臓リハビリテーション学会学術集会
• [Presentation] 摂取蛋白質量は心疾患入院患者の四肢骨格筋量に影響するか (2020)
  • Author(s): 片野唆敏，矢野俊之，神津英至，高村悠平，井上拓也，長岡凌平，大堀克彦，渡辺絢子，石郷友之，本間レミ，藤戸健史，西川 諒，永野伸卓，橋本暁佳，片寄正樹，三浦哲嗣
  • Organizer: 第 26 回日本心臓リハビリテーション学会学術集会
• [Presentation] Clinical significance of fischer ratio in heart failure with reduced ejection fraction (2020)
  • Author(s): 高橋 遼，矢野俊之，神津至英，片野唆敏，井上拓也，高村悠平，西川 諒，永野伸卓，村中敦子，三浦哲嗣
  • Organizer: 第 84 回日本循環器学会学術集会
• [Presentation] Plasma valine-to-glycine ratio is a novel prognostic maker for adverse events in patients with heart failure (2020)
  • Author(s): 神津至英，片野唆敏，矢野俊之，大堀克彦，本間 傑，下村佳奈子，井上拓也，高村悠平，高橋 遼，西川 諒，永野伸卓，小山雅之，藤戸健史，橋本暁佳，三浦哲嗣
  • Organizer: 第 84 回日本循環器学会学術集会
• [Presentation] In addition to malnutrition, comorbidities and pharmacological agents are independent explanatory variables for skeletal muscle mass in chronic heart failure (2020)
  • Author(s): 矢野俊之，片野唆敏，三浦哲嗣
  • Organizer: 第 84 回日本循環器学会学術集会
• [Presentation] Clinical determinants and prognostic impact of osteoporosis in patients with chronic heart failure (2020)
  • Author(s): Katano S., Yano T., Tsukada T., Kouzu H., Honma S., Inoue T., Takamura Y., Nagaoka R., Ohori K., Koyama M., Nagano N., Nishikawa R., Hashimoto A., Katayose M., Miura T.
  • Organizer: ESC congress 2020
  • Int'l Joint Research
• [Presentation] 慢性心不全患者における骨粗鬆症のリスク因子と予後への影響についての検討 (2020)
  • Author(s): 長岡凌平，片野唆敏，矢野俊之，塚田貴紀，神津英至，大堀克彦，本間 傑，井上拓也，高村悠平，渡辺絢子，石郷友之，永野伸卓，橋本暁佳，三浦哲嗣
  • Organizer: 第 23 回日本心不全学会学術集会
• [Presentation] Independent link between peripheral artery disease and muscle wasting in patients with heart failure (2020)
  • Author(s): Ohori K., Yano T., Katano S., Kouzu H., Inoue T., Takamura Y., Ishigo T,. Koyama M., Nagano N., Fujito T., Nishikawa R., Miura T.
  • Organizer: 第 23 回日本心不全学会学術集会
• [Presentation] Prognostic role of plasma amino acid profile in patients with chronic heart failure (2020)
  • Author(s): Kouzu H., Katano S., Yano T., Ohori K., Honma S., Shimomura K., Inoue T., Takamura Y., Takahashi R., Nishikawa R., Nagano N., Koyama M., Fujito T., Hashimoto A., Miura T.
  • Organizer: 第 23 回日本心不全学会学術集会
• [Presentation] 血清クレアチニンによる推定糸球体濾過量過大評価予測スコアの有用性の検討 (2020)
  • Author(s): 石郷友之，片野唆敏，矢野俊之，神津英至，大堀克彦，小山雅之，永野伸卓，藤戸健史，渡辺絢子，中野敬太，近藤 蕗，高田 遼，相神智宏，野々山雅俊，北川 学，木明智子，中田浩雅，橋本暁佳，三浦哲嗣，福土将秀
  • Organizer: 第 14 回日本腎臓病薬物療法学会学術集会・総会
• [Presentation] 心不全患者における形態指標から推定した四肢骨格筋量の予後予測の検討 (2020)
  • Author(s): 本間 傑，片野唆敏，矢野俊之，長岡凌平，神津至英，大堀克彦，渡辺絢子，石郷友之，大和田渉，西川 諒，永野伸卓，小山雅之，片寄正樹，橋本暁佳，小林 史，善岡信博，三浦哲嗣
  • Organizer: 第 85 回日本循環器学会学術集会
• [Presentation] 心不全患者の心臓リハビリテーション施行中の摂取たんぱく質量増加は骨格筋量増加に寄与する (2020)
  • Author(s): 片野唆敏，矢野俊之，神津英至，長岡凌平，大堀克彦，渡辺絢子，石郷友之，仲 詩織，竹内祐子，藤戸健史，大和田渉，西川 諒，永野伸卓，小山雅之，橋本暁佳，三浦哲嗣
  • Organizer: 第 85 回日本循環器学会学術集会
• [Presentation] 高齢心不全患者の筋機能と筋量が ADL 能力に与える影響の検討 (2020)
  • Author(s): 本間 傑，片野唆敏，矢野俊之，大堀克彦，井上拓也，高村悠平，長岡凌平，下村佳奈子，渡辺絢子，善岡信博，橋本暁佳，三浦哲嗣
  • Organizer: 第 23 回日本心不全学会学術集会
• [Presentation] 低栄養状態にある後期高齢心不全患者に対する理学療法の工夫 (2019)
  • Author(s): 片野唆敏，矢野俊之，本間 傑，下村佳奈子，渡辺絢子，大堀克彦，橋本暁佳，三浦哲嗣
  • Organizer: 第 83 回日本循環器学会学術集会
• [Presentation] 慢性腎臓病合併心不全症例の筋消耗評価法：血清クレアチニン・シスタチン C 比と形態計測の比較 (2019)
  • Author(s): 安部功記，片野唆敏，矢野俊之，大堀克彦，神津英至，永野伸卓，藤戸健史，小山雅之，後町 結，茂庭仁人，三浦哲嗣
  • Organizer: 第 62 回日本腎臓学会学術集会
• [Presentation] Low energy intake predicts functional recovery independently of nutritional status in elderly heart failure patients (2019)
  • Author(s): Katano S., Yano T., Honma S., Shimomura K., Ohori K., Fujito T., Watanabe A., Honma R., Ishigo T., Hashimoto A., Miura T.
  • Organizer: Japanese Association of Cardiac Rehabilitation 2019 Annual Meeting in Osaka
  • Int'l Joint Research
• [Presentation] Low energy intake predicts readmission of elderly heart failure patients independently of nutritional status (2019)
  • Author(s): Shimomura K., Katano S., Yano T., Ohori K., Honma S., Watanabe A., Ishigo T., Fujito T., Nagano N., Koyama M., Kouzu H., Hashimoto A., Miura T.
  • Organizer: ESC congress 2019
  • Int'l Joint Research
• [Presentation] Impact of body composition analysis on prediction of short-term readmission events in heart failure: muscle wasting vs. obesity (2019)
  • Author(s): Ohori K., Yano T., Katano S., Honma S., Shimomura K., Watanabe A., Ishigo T., Fuito T., Nagano N., Koyama M., Kouzu H., Hashimoto A., Miura T.
  • Organizer: ESC congress 2019
  • Int'l Joint Research
• [Presentation] 慢性心不全における筋消耗規定因子の検討：サルコペニアを標的とした心不全治療の開発に向けて (2019)
  • Author(s): 矢野俊之，片野唆敏，神津英至，三浦哲嗣
  • Organizer: 第 67 回日本心臓病学会学術集会
• [Presentation] 低栄養状態にある高齢心不全患者の臨床転帰改善に向けた理学療法の可能性 (2019)
  • Author(s): 片野唆敏，本間 傑，下村佳奈子，長岡凌平，高村悠平，井上拓也
  • Organizer: 第 4 回日本心血管理学療法学会・第 6 回日本糖尿病理学療法学会 合同学術大会
• [Presentation] 運動療法と栄養療法の併用によって骨格筋量と身体機能が著明に改善したドキソルビシン心筋症の一症例 (2019)
  • Author(s): 本間 傑，片野唆敏，矢野俊之，下村佳奈子，大堀克彦，善岡信博，橋本暁佳，片寄正樹，三浦哲嗣
  • Organizer: 第 2 回日本腫瘍循環器学会学術集会
• [Presentation] 心不全患者の運動療法を効果的に進めるための積極的栄養管理 (2019)
  • Author(s): 片野唆敏，矢野俊之，大堀克彦，渡辺絢子，下村佳奈子，本間 傑，石郷友之，神津英至，橋本暁佳，三浦哲嗣
  • Organizer: 第 23 回日本心不全学会学術集会
  • Invited
• [Presentation] Predictive accuracy of muscle wasting is improved by combination of anthropometric indicators with nutritional status score in patients with heart failure (2019)
  • Author(s): Katano S., Yano T., Honma S., Ohori K., Inoue T., Takamura Y., Nagaoka R., Hashimoto A. Katayose M., Miura T.
  • Organizer: 12th International SCWD Conference on Cachexia, Sarcopenia & Muscle Wasting
  • Int'l Joint Research
• [Presentation] Determinant of functional status in elderly heart failure patients: muscle function vs. muscle mass (2019)
  • Author(s): Honma S., Katano S., Yano T., Ohori K., Inoue T., Takamura Y., Nagaoka R., Hashimoto A., Yoshioka N., Miura T.
  • Organizer: 12th International SCWD Conference on Cachexia, Sarcopenia & Muscle Wasting
  • Int'l Joint Research
• [Presentation] Clinical determinants of osteoporosis in patients with chronic heart failure (2019)
  • Author(s): 12th International SCWD Conference on Cachexia, Sarcopenia & Muscle Wasting
  • Organizer: Tsukada T., Katano S., Yano T., Honma S., Inoue T., Takamura Y., Ohori K., Hashimoto A., Katayose M., Miura T.
  • Int'l Joint Research
• [Presentation] 高齢心不全では栄養状態に加えて摂取エネルギー量の評価が再入院の予測に有用である (2018)
  • Author(s): 片野唆敏，橋本暁佳，大堀克彦，渡辺絢子，本間レミ，柳瀬理美，石郷友之，藤戸健史，矢野俊之，石合純夫，三浦哲嗣
  • Organizer: 第24回日本心臓リハビリテーション学会学術集会
• [Presentation] 心不全の四肢骨格筋量は形態指標から推定可能か？ (2018)
  • Author(s): 片野唆敏，橋本暁佳，大堀克彦，矢野俊之，藤戸健史，清藤恭貴，伊藤翔太，内澤あゆみ，石合純夫，三浦哲嗣
  • Organizer: 第3回日本心血管理学療法学会学術大会
• [Presentation] 形態計測に加えた栄養状態評価は心不全症例における筋消耗の診断精度を向上させる (2018)
  • Author(s): 片野唆敏，矢野俊之，大堀克彦，渡辺絢子，石郷友之，本間傑，下村佳奈子，本間レミ，津村早紀，永野伸卓，小山雅之，橋本暁佳，三浦哲嗣
  • Organizer: 第22回日本心不全学会学術集会