Investigation of the Mechanism of Intermittent Claudication in Peripheral Arterial Disease and Development of Orthotic Therapy
| Project/Area Number |
18K17746
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| Research Category |
Grant-in-Aid for Early-Career Scientists
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| Allocation Type | Multi-year Fund |
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| Review Section |
Basic Section 59010:Rehabilitation science-related
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| Research Institution | The University of Tokyo (2020-2022)
Tohoku University (2018-2019) |
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Principal Investigator |
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| Project Period (FY) |
2018-04-01 – 2023-03-31
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| Project Status |
Completed (Fiscal Year 2022)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2021: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2020: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2019: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2018: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 末梢動脈疾患 / 間歇性跛行 / 三次元動作解析 / 装具療法 / 運動療法 |
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| Outline of Final Research Achievements |
This study aimed to analyze intermittent claudication (IC) associated with peripheral arterial disease (PAD) from a kinematic perspective and to collect data for the development of orthotic therapy based on the results. Due to COVID-19, it was impossible to collect research data using orthotic therapy. Therefore, to analyze whether pain itself is related to gait, a before and after comparison using endovascular therapy (EVT) was conducted. The results indicated that pain was involved in the gait of PAD patients and that treatment strategies such as a combination of EVT and exercise therapy were necessary for improvement.
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| Academic Significance and Societal Importance of the Research Achievements |
PADに伴うICは血管疾患であるがゆえ、歩容にはこれまで着目されてこなかった。本研究により、痛みそのものが歩容に関係することが示唆された。また、痛みが取れた際に、股関節の関節モーメントやパワーが改善することが明らかになった。今後、股関節の働きを補助する装具の開発はICの改善に寄与できると考えられる。ICに伴う歩行速度や歩行距離の低下は患者の予後に直結するとされている。本研究の結果により、装具等の開発が進み、手術せずとも患者の歩行パフォーマンスを改善することで、PAD患者のQOLや生命予後の改善の一助になると考えている。
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Report
(6 results)
Research Products
(18 results)
