| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2020: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Outline of Final Research Achievements |
In this study, in order to elucidate the molecular biological mechanism of muscle memory, we focused on the relationship between muscle memory and ribosome genesis. First, we constructed a cell model suitable for investigating the molecular biological mechanism of muscle memory and established a method using decellularized skeletal muscle as a substrate for skeletal muscle cell culture system. This has enabled us to study the relationship between the extracellular matrix and skeletal muscle cells, which is important in the mechanoreceptor mechanism of skeletal muscle. We are currently using this model to analyze data applied to the elucidation of the molecular biological mechanism of muscle memory.
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