身体活動が認知機能を改善・発達させる神経ネットワークの同定
Project/Area Number |
18K17832
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Research Category |
Grant-in-Aid for Early-Career Scientists
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Allocation Type | Multi-year Fund |
Review Section |
Basic Section 59020:Sports sciences-related
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Research Institution | Kobe University (2020-2021) Hokkaido University (2019) Tamagawa University (2018) |
Principal Investigator |
石原 暢 神戸大学, 人間発達環境学研究科, 助教 (10801631)
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Project Period (FY) |
2018-04-01 – 2023-03-31
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Project Status |
Granted (Fiscal Year 2021)
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Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2020: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2019: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2018: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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Keywords | 身体活動 / 体力 / 認知機能 / 磁気共鳴画像法 / 反応抑制 / ワーキングメモリー / 生理学 / 運動生理学 / 認知科学 |
Outline of Annual Research Achievements |
近年の研究により、身体活動は加齢に伴う認知機能の衰退予防だけでなく、子どもから青年期においても認知機能を改善、発達させるための1つの手段となり得ることが報告されている。しかし、身体活動が脳構造や機能に与える効果に関する知見は乏しい状況にある。磁気共鳴画像 (MRI) を用いた研究により、身体活動は前頭前野背外側部や海馬の体積を増大させることが報告されているものの、脳の機能レベルで身体活動の効果を理解するためには、脳領域間の解剖学的ならびに神経活動レベルでの繋がりの変化を調べる必要がある。 そこで本研究では、近年公開されたMRIで脳の構造・機能をより正確かつ詳細に計測・解析できる Human Connectome Project (HCP) 準拠のプロトコールで撮像したMRIデータ、ならびに解析パイプラインを用いて、20歳から60歳の健常者を対象に身体活動量と認知機能の成績に関わる脳の構造・機能的領域間結合の関連を詳細に検討し、身体活動が認知機能を改善、発達させる背景にある神経ネットワークの変化を明らかにすることを目的としている。 令和3年度にはマルチモーダルMRIデータ(T1, T2, rs-fMRI, dMRI)の解析手法を確立し、データ分析および論文執筆を順調に進めた。
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Current Status of Research Progress |
Current Status of Research Progress
3: Progress in research has been slightly delayed.
Reason
新型コロナウイルス感染症の対応のため、データの収集に遅延が遅れたため、その分データ分析と論文執筆に遅れが出ているため。
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Strategy for Future Research Activity |
2022年度は引き続き得られたデータの分析、学会での成果報告、論文化を進める予定である。
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Report
(4 results)
Research Products
(62 results)
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[Journal Article] Modeling relationships of achievement motivation and physical fitness to academic performance in Japanese schoolchildren: Moderation by gender2018
Author(s)
Ishihara, T., Morita, N., Nakajima, T., Okita, K., Sagawa, M., & Yamatsu, K.
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Journal Title
Physiology & Behavior
Volume: 194
Pages: 66-72
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Presentation] Playing in online eSport tournament enhances psychological vigor with neurohumoral responses to winning or losing2021
Author(s)
Matsui, T., Monma, T., Sagayama, H., Hyodo, K., Shima, T., Ishihara, T., Fujii, N., & Takagi, H.
Organizer
44th Annual Meeting of the Japan Neuroscience Society
Related Report
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[Presentation] Development of inequity aversion: A cross sectional study from adolescence to adulthood2021
Author(s)
Shou, Q., Miyazaki, A., Yamada, J., Tanaka, H., Ishihara, T., Fujii, T., Takahashi, M., Okada, H., Matsuda, T., & Takagishi, H.
Organizer
The 32nd International Congress of Psychology
Related Report
Int'l Joint Research
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[Presentation] Developmental changes in trust and reciprocity: Cross sectional study from adolescence to adulthood2021
Author(s)
Yamada, J., Miyazaki, A., Shou, Q., Tanaka, H., Ishihara, T., Fujii, T., Takahashi, M., Okada, H., Matsuda, T., & Takagishi, H.
Organizer
The 32nd International Congress of Psychology
Related Report
Int'l Joint Research
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[Presentation] Association between children’s physical fitness and performance on academic subjects2020
Author(s)
Ishihara, T., Kamijo, K., Nakajima, T., Yamatsu, K., Okita, K., Sagawa, M., & Morita, N.
Organizer
The 2020 Yokohama Sport Conference
Related Report
Int'l Joint Research
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[Presentation] Relationship of multiple aspects of physical fitness to cognitive control: An fMRI investigation with over 1,000 young and middle-aged adults2019
Author(s)
Ishihara, T., Miyazaki, A., Tanaka, H., Fujii, T., Takahashi, M., & Matsuda, T.
Organizer
24th Annual Congress of the European College of Sport Science
Related Report
Int'l Joint Research
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[Presentation] Modeling the relationship of physical fitness to working memory via fMRI activation and performance2019
Author(s)
Ishihara, T., Miyazaki, A., Tanaka, H., Fujii, T., Takahashi, M., & Matsuda, T.
Organizer
25th Annual Meeting of the Organization for Human Brain Mapping
Related Report
Int'l Joint Research
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[Presentation] The relationship between obesity and age-related structural brain changes: A multimodal MRI study using the Human Connectome Project-style paradigm2019
Author(s)
Ishihara, T., Miyazaki, A., Tanaka, H., Fujii, T., Takahashi, M., Matsumoto, Y., Kiyonari, T., Takagishi, H., & Matsuda, T.
Organizer
42nd Annual Meeting of the Japan Neuroscience Society
Related Report
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[Presentation] Relationship of multiple aspects of physical fitness to cognitive control: An fMRI investigation with over 1,000 young and middle-aged adults.2019
Author(s)
Ishihara, T., Miyazaki, A., Tanaka, H., Fujii, T., Takahashi, M., & Matsuda, T.
Organizer
European Collage of Sport Science
Related Report
Int'l Joint Research
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[Presentation] Modeling the relationship of physical fitness to working memory via fMRI activation and performance.2019
Author(s)
Ishihara, T., Miyazaki, A., Tanaka, H., Fujii, T., Takahashi, M., & Matsuda, T.
Organizer
Organization for Human Brain Mapping Annual Meeting
Related Report
Int'l Joint Research
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[Presentation] Childhood sports and adulthood inhibition: A large-scale multimodal imaging study using HCP pipeline.2018
Author(s)
Ishihara, T., Miyazaki, A., Takagishi, H., Fujii, T., Kanari, K., Nishina, K., Takahashi, M., Tanaka, H., Yamagishi, T., & Matsuda, T.
Organizer
Organization for Human Brain Mapping Annual Meeting
Related Report
Int'l Joint Research
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[Presentation] Influence of childhood exercise on cognitive functions and related brain structure and neural network in adulthood: Evaluation using Human Connectome Project pipeline2018
Author(s)
Ishihara, T., Miyazaki, A., Takagishi, H., Fujii, T., Kanari, K., Nishina, K., Takahashi, M., Tanaka, H., Yamagishi, T., & Matsuda, T.
Organizer
Japan Neuroscience Society
Related Report
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[Book] 自己制御の発達と支援2018
Author(s)
森口佑介, 本郷一夫, 石原暢, 紙上敬太
Total Pages
120
Publisher
金子書房
ISBN
9784760895748
Related Report