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A longitudinal study of stress tolerance related to regional brain volume change based on deep emotion

Research Project

Project/Area Number 18K17932
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 59040:Nutrition science and health science-related
Research InstitutionTohoku Medical and Pharmaceutical University

Principal Investigator

Nakagawa Seishu  東北医科薬科大学, 医学部, 准教授 (30450703)

Project Period (FY) 2018-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2020: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2019: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2018: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords職場適応 / 深層感情 / 表層状態 / 敵意 / 仕事中毒 / 自己効力感 / 慢性疲労 / 混乱・当惑 / ストレス耐性 / 可塑性 / 脳局所量 / うつ状態 / 適応障害 / ストレス反応 / 孤独感 / 完璧主義 / MRI画像 / ストレス / 脳の可塑性 / MRI
Outline of Final Research Achievements

A research has been conducted on 24 patients (14 males, 10 females, average age 38±10 years old) who had been diagnosed with stress-related disorders, adjustment disorders, and depressive disorders due to workplace stress. Two surveys (at entry and 6 months later) were conducted using a self-questionnaire about surface states and deep emotions. Chronic fatigue, confusion/bewilderment (surface state), and workaholism (deep emotion) improved significantly as work adaptation improved. Those strongly related to work adaptation were hostility (deep emotion) and tension/anxiety (surface state) at the time of entry, and self-efficacy (deep emotion) and confusion/bewilderment after 6 months. Analysis of MRI brain images is also currently underway.

Academic Significance and Societal Importance of the Research Achievements

精神的健康対策は、企業の健康管理室や臨床現場では必須である。職場の適応には、表層状態(うつ状態、慢性疲労、不安・困惑)のみならず、否定的な深層感情(孤独感、敵意、完璧主義、仕事中毒、低い自己効力感)が強く関わっているが、表出しにくい側面でもある。治療初期と治療後では、職場適応に影響を及ぼす表層状態や深層感情の要因が異なると、臨床経験から予測した。6か月の治療により、仕事適応の改善に伴い深層感情で改善したものは唯一「仕事中毒」のみであった。職場の健康管理において、本人のセルフケア対策のみでは限界があり、上司・同僚、医療従事者を含めて、深層感情に焦点を当てた治療介入が必要なことが示唆された。

Report

(6 results)
  • 2022 Annual Research Report   Final Research Report ( PDF )
  • 2021 Research-status Report
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (7 results)

All 2023 2021 2019

All Journal Article (1 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 1 results) Presentation (6 results) (of which Int'l Joint Research: 3 results)

  • [Journal Article] Cortico-striatal-thalamic loop as a neural correlate of neuroticism in the mind-body interface2021

    • Author(s)
      Seishu Nakagawa, Hikaru Takeuchi, Yasuyuki Taki, Rui Nouchi, Yuka Kotozaki, Takamitsu Shinada, Tsukasa Maruyama , Atsushi Sekiguchid, Kunio Iizuka , Ryoichi Yokoyama, Yuki Yamamoto, Sugiko Hanawa , Tsuyoshi Araki , Carlos Makoto Miyauchi , Daniele Magistro, Kohei Sakaki , Hyeonjeong Jeong, Ryuta Kawashima
    • Journal Title

      Journal of Psychosomatic Research

      Volume: 149 Pages: 110590-110590

    • DOI

      10.1016/j.jpsychores.2021.110590

    • Related Report
      2021 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] 職場適応における表層状態と深層感情の解離2023

    • Author(s)
      中川 誠秀、丹生谷 正史、櫻田 久美、吉村 淳、鈴木映二
    • Organizer
      第119回日本精神神経学会学術総会
    • Related Report
      2022 Annual Research Report
  • [Presentation] 第20回うつ病学会総会2023

    • Author(s)
      中川 誠秀、丹生谷 正史、櫻田 久美、吉村 淳、鈴木映二
    • Organizer
      適応と関連のある気分・感情要因と治療時期での相違
    • Related Report
      2022 Annual Research Report
  • [Presentation] 睡眠習慣の相違によるうつ状態と慢性疲労との弁別2021

    • Author(s)
      中川誠秀,竹内光,瀧靖之,野内類,関口敦,宮内誠カルロス,飯塚邦夫,横山諒一,塙杉子,榊浩平,Hyeonjeong Jeong,川島隆太
    • Organizer
      第17回第日本うつ病学会
    • Related Report
      2020 Research-status Report
  • [Presentation] The effects of deep emotions on chronic fatigue in young adults2019

    • Author(s)
      Seishu Nakagawa
    • Organizer
      19th World congress of Psychiatry, World Psychiatry Association
    • Related Report
      2019 Research-status Report
    • Int'l Joint Research
  • [Presentation] The effects of deep emotions on chronic fatigue in young adults2019

    • Author(s)
      Seishu Nakagawa, Hikaru Takeuchi, Yasuyuki Taki, Rui Nouchi, Yuka Kotozaki, Takamitsu Shinada, Tsukasa Maruyama, Atsushi Sekiguchi, Kunio Iizuka, Ryoichi Yokoyama, Yuki Yamamoto, Sugiko Hanawa, Tsuyoshi Araki, Carlos Makoto Miyauchi, Daniele Magistro, Kohei Sakaki, Hyeonjeong Jeong, Yukako Sasaki, Ryuta Kawashima
    • Organizer
      19th WPA World Congress of Psychiatry
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] Neural correlates of guilty feelings in young adults2019

    • Author(s)
      Seishu Nakagawa, Hikaru Takeuchi, Yasuyuki Taki, Rui Nouchi, Yuka Kotozaki, Takamitsu Shinada, Tsukasa Maruyama, Atsushi Sekiguchi, Kunio Iizuka, Ryoichi Yokoyama, Yuki Yamamoto, Sugiko Hanawa, Tsuyoshi Araki, Carlos Makoto Miyauchi, Daniele Magistro, Kohei Sakaki, Hyeonjeong Jeong, Yukako Sasaki, Ryuta Kawashima
    • Organizer
      2019 Cognitive Neuroscience (CNS) Annual Meeting
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research

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Published: 2018-04-23   Modified: 2024-01-30  

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