| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2020: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2019: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2018: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
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| Outline of Final Research Achievements |
In order to investigate the relationship between sarcopenia risk and salt intake, a human study compared the salt intake calculated from the occasional urine of 114 healthy male and female volunteers, and as a result, the high salt intake group was compared with the low salt intake group. In comparison, body weight, body weight index, body fat percentage, and blood IL-6, triglyceride, insulin, and ALT levels increased significantly, grip / body weight, long-seat anteflexion (flexibility), 30-second chair. The rise test was significantly reduced.
In a mouse study, 10-month-old mice were fed a diet containing 8% NaCl for 4 weeks to examine changes in gene expression in skeletal muscle. As a result, it was found that various gene expressions were changed by gene expression analysis using next-generation sequencing.
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