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Lock-in detection beyond the quantum limit based on the delayed interference of squeezed light and optical pulses

Research Project

Project/Area Number 18K18847
Research Category

Grant-in-Aid for Challenging Research (Exploratory)

Allocation TypeMulti-year Fund
Review Section Medium-sized Section 21:Electrical and electronic engineering and related fields
Research InstitutionThe University of Tokyo

Principal Investigator

Ozeki Yasuyuki  東京大学, 大学院工学系研究科(工学部), 准教授 (60437374)

Project Period (FY) 2018-06-29 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2019: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2018: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Keywords光パルス / 生体イメージング / 誘導ラマン散乱 / 量子光学 / スクイージング / バランスド検出 / 顕微鏡
Outline of Final Research Achievements

To further improve the sensitivity of molecular imaging methods using nonlinear optical effects and the lock-in detection, we proposed a lock-in detection method with ultrahigh sensitivity beyond the standard quantum limit. We have obtained the following results. (1) The effect of optical loss on the squeezing level was clarified. (2) A beam shaping method using axicons was examined and demonstrated to realize an ultra-low-loss optical system for using squeezed light. (3) The effects of pulse chirp and group velocity dispersion in the nonlinear-optical crystal on the squeezing level were clarified. (4) We conducted imaging experiments of boron cluster compounds and plant samples using the existing lock-in based microscope.

Academic Significance and Societal Importance of the Research Achievements

本研究成果の学術的意義は、スクイージングという先端的な量子科学技術の応用を大きく広げ、様々な光学計測手法の性能の向上に貢献できる点である。特に、生体計測技術の高速化が急速に進展し、その計測感度限界が光の量子雑音にある現状を鑑みると、標準量子限界を超える計測技術の創出は急務である。実際、本研究課題の申請書に記載した振幅スクイージング法を誘導ラマン散乱顕微法に用いる報告が2020年にデンマーク・オーストラリアの量子光学グループが報告しており、また、同様に申請書記載の量子増強法の研究を研究代表者が継続している。残念ながら本研究提案の実証には至っていないが、今後の研究を通じて実証を図る予定である。

Report

(3 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • Research Products

    (18 results)

All 2020 2019 Other

All Journal Article (4 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 4 results) Presentation (13 results) (of which Int'l Joint Research: 3 results,  Invited: 4 results) Remarks (1 results)

  • [Journal Article] Time-domain analysis on the pulsed squeezed vacuum detected with picosecond pulses2020

    • Author(s)
      Taguchi Yoshitaka、Ozeki Yasuyuki
    • Journal Title

      Journal of the Optical Society of America B

      Volume: -

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Axicon-based beam shaping for low-loss nonlinear microscopic optics2019

    • Author(s)
      Ochiai Natsuha、Shou Jingwen、Ozeki Yasuyuki
    • Journal Title

      Journal of the Optical Society of America B

      Volume: 36 Issue: 5 Pages: 1342-1342

    • DOI

      10.1364/josab.36.001342

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Imaging of cellular uptake of boron cluster compound by stimulated Raman scattering microscopy2019

    • Author(s)
      Asai, Takuya Liu, Hanqin Ozeki, Yasuyuki Sato, Shinichi Hayashi, Tomohiro Nakamura, Hiroyuki
    • Journal Title

      Applied Physics Express

      Volume: 12 Issue: 11 Pages: 112004-112004

    • DOI

      10.7567/1882-0786/ab4a5d

    • NAID

      210000157252

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Axicon-based beam shaping for low loss nonlinear microscopic optics2019

    • Author(s)
      N. Ochiai, J. Shou, and Y. Ozeki
    • Journal Title

      J. Opt. Soc. Am. B

      Volume: 印刷中

    • Related Report
      2018 Research-status Report
    • Peer Reviewed
  • [Presentation] High-speed super-multiplex organelle imaging2020

    • Author(s)
      J. Shou, F. Hu, R. Oda, W. Min, and Y. Ozeki
    • Organizer
      Photonics West, BiOS, paper 11252-45, 2020.
    • Related Report
      2019 Annual Research Report
  • [Presentation] High speed imaging of B-cells by stimulated Raman scattering2020

    • Author(s)
      R. Oda, J. Shou, B. Shiramizu, and Y. Ozeki
    • Organizer
      Photonics West, BiOS, paper 11252-29, 2020.
    • Related Report
      2019 Annual Research Report
  • [Presentation] 生体分子イメージングにおける量子増強に向けて2019

    • Author(s)
      小関 泰之
    • Organizer
      第80回応用物理学会秋季学術講演会シンポジウム「光が拓く量子技術の新展開」、19p-E301-3、北海道大学、2019年9月19日。
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Multicolor stimulated Raman and fluorescence imaging with high-speed programmable tunability2019

    • Author(s)
      J. Shou, R. Oda, S. Tanaka, and Y. Ozeki
    • Organizer
      Conference on Lasers and Electro-Optics (CLEO2019), paper STu4H.6, May 7, 2019.
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Beam shaping with axicons for low loss microscopy optics2019

    • Author(s)
      N. Ochiai, J. Shou, and Y. Ozeki
    • Organizer
      Conference on Lasers and Electro-Optics (CLEO2019), paper JW2A.83, May 7, 2019.
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] パルススクイージングにおけるチャープ及びウォークオフの影響2019

    • Author(s)
      田口 富隆、小関 泰之
    • Organizer
      第80回応用物理学会秋季学術講演会、21a-E207-4、北海道大学、2019年9月21日。
    • Related Report
      2019 Annual Research Report
  • [Presentation] 量子増強イメージングのための顕微光学系の透過率評価2019

    • Author(s)
      落合 夏葉、寿 景文、飯野 敬矩、小関 泰之
    • Organizer
      第80回応用物理学会秋季学術講演会、21a-E207-3、北海道大学、2019年9月21日。
    • Related Report
      2019 Annual Research Report
  • [Presentation] 高機能パルスレーザーによる誘導ラマンイメージング2019

    • Author(s)
      小関泰之
    • Organizer
      超高速光エレクトロニクス研究会第1回研究会、電気通信大学、2019年9月27日。
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 誘導ラマン散乱による分子振動イメージングとその応用2019

    • Author(s)
      小関泰之
    • Organizer
      医用分光学研究会、資生堂グローバルリサーチセンター、2019年11月21日。
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] Multicolor stimulated Raman scattering microscopy with functional lasers2019

    • Author(s)
      Y. Ozeki
    • Organizer
      Biomedical Raman Imaging (BRI2019), Osaka Univ., Nov. 24, 2019.
    • Related Report
      2019 Annual Research Report
    • Invited
  • [Presentation] 誘導ラマン散乱顕微法による分子振動イメージングとその応用2019

    • Author(s)
      小関泰之、飯野敬矩
    • Organizer
      イメージングフロンティアセンターシンポジウム、2019年12月14日。
    • Related Report
      2019 Annual Research Report
  • [Presentation] 低損失顕微光学系のためのアキシコンを用いたビーム整形法2019

    • Author(s)
      落合夏葉、寿景文、小関泰之
    • Organizer
      第66回応用物理学会春季学術講演会、9a-W641-7、2019年3月9日
    • Related Report
      2018 Research-status Report
  • [Presentation] Beam Shaping with Axicons for Low Loss Microscopy Optics2019

    • Author(s)
      Natsuha Ochiai, Jingwen Shou, Yasuyuki Ozeki
    • Organizer
      Conference on Lasers and Electro-Optics,
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Remarks] Ozeki Group

    • URL

      https://sites.google.com/site/ozekibp/

    • Related Report
      2019 Annual Research Report

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Published: 2018-07-25   Modified: 2021-02-19  

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