Molecular basis on cannibalism
Project/Area Number |
18K19266
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Research Category |
Grant-in-Aid for Challenging Research (Exploratory)
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Allocation Type | Multi-year Fund |
Review Section |
Medium-sized Section 42:Veterinary medical science, animal science, and related fields
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Research Institution | Tokyo University of Agriculture and Technology |
Principal Investigator |
Shimmura Tsuyoshi 東京農工大学, (連合)農学研究科(研究院), 准教授 (50707023)
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Project Period (FY) |
2018-06-29 – 2021-03-31
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Project Status |
Completed (Fiscal Year 2020)
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Budget Amount *help |
¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2020: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2019: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2018: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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Keywords | 共喰い / カニバリズム / 全ゲノムシークエンス / 集団ゲノム解析 / RNA-seq |
Outline of Final Research Achievements |
The purpose of this study was to clarify the molecular basis of cannibalism that is widely reported in the animal kingdom. We conducted a large-scale phenotypic analysis of Japanese chicken bioresources, discovered populations showing different frequency of cannibalism in the same breed, and used these populations to integrate the whole genome and RNA-seq by next-generation sequencing. Finally, we clarified the candidate genes and their molecular mechanism that regulate cannibalism.
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Academic Significance and Societal Importance of the Research Achievements |
21世紀以降、家畜福祉(アニマルウェルフェア)はグローバルスタンダードとなり、ニワトリ用のケージ飼育が世界的に禁止となり、広い空間に数千羽以上を放し飼いにする管理方法への移行が始まっている。しかしながら、そこではニワトリ同士の共喰いが多発するため、この問題行動の遺伝的制御が世界的な課題となっている。本研究は、この課題を遺伝的に解決するための基盤を明らかにした。
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Report
(4 results)
Research Products
(15 results)
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[Journal Article] The quail genome: insights into social behaviour, seasonal biology and infectious disease response2020
Author(s)
Morris KM, Hindle MM, Boitard S, Burt DW, Danner AF, Eory L, Forrest HL, Gourichon D, Gros J, Hillier L, Jaffredo T, Khoury H, Leterrier C, Loudon A, Mason AS, Meddle SL, Minvielle1 F, Minx P, Pitel F, Seiler JP, Shimmura T, Tomlinson C, Vignal A, Webster RG, Yoshimura T, Warren WC, Smith J
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Journal Title
BMC Biology
Volume: 18
Issue: 1
Pages: 1-14
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Seasonal changes in NRF2 antioxidant pathway regulates winter depression-like behavior2020
Author(s)
Nakayama T, Okimura K, Shen J, Guh Y-J, Tamai K, Shimada A, Minou S, Okushi Y, Shimmura T, Furukawa Y, Kadofusa N, Sato A, Nishimura T, Tanaka M, Nakayama K, Shiina N, Yamamoto N, Loudon A.S, Nishiwaki-Ohkawa T, Shinomiya A, Nabeshima T, Nakane Y, and Yoshimura T
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Journal Title
PNAS
Volume: -
Issue: 17
Pages: 1-10
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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[Journal Article] Seasonally regulation of the lncRNA LDAIR modulates self-protective behaviors during the breeding season.2019
Author(s)
Nakayama T., Shimmura, T., Shinomiya, A., Okimura, K., Takehana,Y., Furukawa, Y., Shimo, T., Senga, T., Nakatsukasa, M., Nishimura, T., Tanaka, M., Okubo, K., Kamei, Y., Naruse, K. and Yoshimura, T.
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Journal Title
Nature Eco. Evol.
Volume: 3
Issue: 5
Pages: 845-852
DOI
Related Report
Peer Reviewed / Open Access
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