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Latent growth modelling of signs preceding dementia as certified in the Long-Term Care Insurance System

Research Project

Project/Area Number 18K19718
Research Category

Grant-in-Aid for Challenging Research (Exploratory)

Allocation TypeMulti-year Fund
Review Section Medium-sized Section 58:Society medicine, nursing, and related fields
Research InstitutionTokyo Metropolitan Geriatric Hospital and Institute of Gerontology

Principal Investigator

Amano Hidenori  地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究助手 (90260306)

Project Period (FY) 2018-06-29 – 2024-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2020: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2019: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2018: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Keywords介護保険 / 認知症 / 意欲低下 / 抑うつ / 要介護認定 / 類型化 / 危険因子 / 多様性 / 縦断研究
Outline of Final Research Achievements

Although apathy is known to indicate higher risk of dementia incidence in the setting of memory clinic, its predictive value in community dwellers remains to be elucidated. The present study suggests that apathy symptoms are informative to predict dementia in sub groups of community dwellers, including younger olds and those with mildly declined performance in cognitive tests.

Academic Significance and Societal Importance of the Research Achievements

物忘れ外来受診者の中では意欲低下者の予後が悪いことが知られているが、一般高齢者における意欲低下所見の意義は確立されていない。本研究は、一般高齢者の中の特定の集団において、意欲低下が認知症リスクを高めることを示した。

Report

(6 results)
  • 2023 Final Research Report ( PDF )
  • 2022 Research-status Report
  • 2021 Research-status Report
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (5 results)

All 2023 2020 2019 2018

All Presentation (5 results) (of which Int'l Joint Research: 2 results)

  • [Presentation] Apathetic symptoms and the risk of incident dementia certified in the Long-Term Care Insurance System: a 12-year cohort study of the community dwelling elderly in Japan2023

    • Author(s)
      Amano H, Nofuji Y, Seino S, Yokoyama Y, Abe T, Yamashita M, Hata T, Shinkai S, Kitamura A, and Fujiwara Y
    • Organizer
      IAGG Asia/Oceania Regional Congress 2023
    • Related Report
      2022 Research-status Report
    • Int'l Joint Research
  • [Presentation] 地域高齢者における意欲低下・抑うつ・認知機能低下と「認知症」発症リスクー会場健診と要介護認定審査に基づくコホート研究ー2020

    • Author(s)
      天野秀紀 北村明彦 西真理子 野藤悠 清野諭 横山友里 成田美紀 池内朋子 吉田裕人 藤原桂典
    • Organizer
      第35回日本老年精神医学会
    • Related Report
      2020 Research-status Report
  • [Presentation] 要介護認定で見られる「認知症」の多様性:発症時重症度と発症前認知機能・抑うつ関連症状の推移に基づく類型化2020

    • Author(s)
      天野 秀紀、北村 明彦、西 真理子、野藤 悠、清野 諭、横山 友里、藤原 佳典、新開 省二
    • Organizer
      第30回日本疫学会学術総会
    • Related Report
      2019 Research-status Report
  • [Presentation] 要介護認定で見られる「認知症」の発症様式・発症前認知機能変化に基づく類型化と類型別危険因子2019

    • Author(s)
      天野秀紀、北村明彦、横山友里、成田美紀、西真理子、谷口優、清野諭、吉田裕人、藤原佳典、新開省二
    • Organizer
      第61回日本老年医学会学術集会
    • Related Report
      2018 Research-status Report
  • [Presentation] Risk factors for types of dementia classified on multivariate trajectories of cognitive functions before incidence2018

    • Author(s)
      Amano H, Kitamura A, Yokoyama Y, Narita M, Nishi M, Yoshida H, Fujiwara Y, and Shinkai S
    • Organizer
      The Gerontological Society of America’s 2018 Annual Scientific Meeting
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research

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Published: 2018-07-25   Modified: 2025-01-30  

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