Relationship between the mixing state of atmospheric aerosol particles and their lung deposition: Analysis toward next-generation assessments of the health effects

• Project/Area Number: 18K19852
• Research Category: Grant-in-Aid for Challenging Research (Exploratory)
• Allocation Type: Multi-year Fund
• Review Section: Medium-sized Section 63:Environmental analyses and evaluation and related fields
• Research Institution: Nagoya University
• Principal Investigator: Mochida Michihiro 名古屋大学, 宇宙地球環境研究所, 教授 (10333642)
• Project Period (FY): 2018-06-29 – 2020-03-31
• Project Status: Completed (Fiscal Year 2019)
• Budget Amount: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000); Fiscal Year 2019: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000); Fiscal Year 2018: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
• Keywords: 大気エアロゾル / 肺沈着 / 混合状態 / 吸湿性 / 健康影響 / エアロゾル / 呼吸器 / 沈着

Outline of Final Research Achievements

By utilizing the measurement data of the hygroscopic growth of atmospheric aerosols in Nagoya in September 2009, the respiratory deposition of atmospheric aerosol particles that a person inhaled was analyzed. The characteristics of the deposition of aerosol particles in the respiratory tract during the period was obtained based on the distributions of aerosol particles as a function of the dry diameter and hygroscopicity. Further, the importance of the consideration of the external mixing state of aerosols during the period was assessed. The influence of the consideration of time evolution on the calculation of the deposition, and the representation of the results from the analysis were studied.

Academic Significance and Societal Importance of the Research Achievements

微小粒子状物質(PM2.5)の環境基準として用いられているように、大気微粒子の質量濃度はその健康影響の重要な尺度であるが、質量濃度のみで健康影響を十分に説明できるとは考えにくい。本研究では、大気微粒子の乾燥粒径と吸湿性の分布が人の呼吸器内における微粒子の挙動に関係することに着目し、これらの大気観測データに基づいて呼吸器内の沈着の特徴付けを行った。今後、大気微粒子の性状と呼吸器内沈着の関係について研究が発展することで、大気微粒子の健康影響のより正確な理解が得られることが期待される。

Research Products

• [Presentation] 大気エアロゾルの粒径分布と吸湿性の呼吸器沈着率への影響に関する事例分析 (2019)
  • Author(s): 王敏睿，三原利之， 梶野瑞王，川名華織，持田陸宏
  • Organizer: 日本地球惑星科学連合2019年大会
• [Presentation] Hygroscopic properties of water-soluble matter in atmospheric submicrometer aerosol collected in Okinawa (2019)
  • Author(s): Yange Deng, Hiroaki Fujinari, Hikari Yai, Kojiro Shimada, Shiori Tatsuta, Shiro Hatakeyama, Yutaka Kondo, Akinori Takami, Yuzo Miyazaki, Eri Tachibana, Mingfu Cai, Hanbing Xu, Fei Li, Haobo Tan, Tomoki Nakayama, Petr Vodicka, Dhananjay K. Deshmukh, Kimitaka Kawamura, and Michihiro Mochida
  • Organizer: 第24回大気化学討論会
• [Presentation] 都市大気エアロゾルの吸湿性分布とその呼吸器沈着の関係 (2018)
  • Author(s): 三原利之, 持田陸宏, 梶野瑞王, 川名華織
  • Organizer: 第35回エアロゾル科学・技術研究討論会