The high-speed dose calculation technology for human geometry which allows performing the high precision Monte-Carlo treatment planning
| Project/Area Number |
18K19899
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| Research Category |
Grant-in-Aid for Challenging Research (Exploratory)
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| Allocation Type | Multi-year Fund |
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| Review Section |
Medium-sized Section 90:Biomedical engineering and related fields
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| Research Institution | University of Tsukuba |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
高田 健太 群馬県立県民健康科学大学, 診療放射線学部, 准教授 (10640782)
佐藤 達彦 国立研究開発法人日本原子力研究開発機構, 原子力科学研究部門 原子力科学研究所 原子力基礎工学研究センター, 研究主席 (30354707)
古田 琢哉 国立研究開発法人日本原子力研究開発機構, 原子力科学研究部門 原子力科学研究所 原子力基礎工学研究センター, 研究主幹 (40604575)
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| Project Period (FY) |
2018-06-29 – 2021-03-31
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| Project Status |
Completed (Fiscal Year 2020)
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| Budget Amount *help |
¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2020: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2019: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2018: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 治療計画 / モンテカルロ法 / BNCT / 線量計算 / 並列計算 / 四面体法 / ボクセル法 / 線量評価 / モンテカルロ計算 / 人体モデル / 放射線治療技術学 / ホウ素中性子捕捉療法 / 連続四面体法 / メニーコア / 連続四面体 |
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| Outline of Final Research Achievements |
A calculation model for a patient's head created by Tsukuba-Plan that is a treatment planning system was converted into a model constructed by the tetrahedron method and then calculation performance for the model has been evaluated. The results demonstrated that the calculation time can be shortened by about 50% compared to the conventional voxel method by adopting the tetrahedral method. In addition, PHITS as a Monte Carlo-based calculation code has been improved so that Monte Carlo calculations can be performed using the tetrahedral method.
As an issue that became clear in this research, when defining a complicated calculation model like a human head by the tetrahedron method, the material undefined area of the space definition or the material overlapping area in the complicated curved surface part with the current Tsukuba-plan technology Will occur. We wish to improve the system so that a tetrahedron model can be created automatically.
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| Academic Significance and Societal Importance of the Research Achievements |
難治がん、再発がんの治療法の確立は人類の大きな課題である。がん治療法の中で放射線治療分野において必須である治療計画/線量評価作業において、モンテカルロ法を用いることで線量評価精度が高くなり、より適切な治療が期待できるが、計算時間が長時間かかるため、実用的ではなかった。本研究により、モンテカルロ法による線量評価の高速化、短時間化の見通しを得ることができた。これにより、放射線治療によるがん治療の高精度化を図ることができ、ひいては治療成績の向上に寄与できることが期待できる。
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Report
(4 results)
Research Products
(28 results)
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[Journal Article] Evaluation of the characteristics of the neutron beam of a linac-based neutron source for boron neutron capture therapy2020
Author(s)
Kumada Hiroaki, Takada Kenta, Tanaka Susumu, Matsumoto Yoshitaka, Naito Fujio, Kurihara Toshikazu, Sugimura Takashi, Sato Masaharu, Matsumura Akira, Sakurai Hideyuki, Sakae Takeji
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Journal Title
Applied Radiation and Isotopes
Volume: 165
Pages: 109246-109246
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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