| Budget Amount *help |
¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2020: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2019: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2018: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Outline of Final Research Achievements |
A treatment method for regenerating and repairing degenerative cartilage in osteoarthritis has not been established, and there is no technique for identifying pathological changes of degenerative cartilage at an extremely early phase. In this study, we succeeded in identifying changes in the molecular composition of the extra-cellular matrix of cartilage by performing Raman spectroscopic analysis on the specimens removed in total knee replacement.
We also create a prototype of the device to be mounted on an arthroscope for surgery, based on that system. We plan to apply these devices clinically in the future.
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