International collaborative studies to establish tailormade therapy based on the virulence and antibiotics resistance of H. pylori

• Project/Area Number: 18KK0266
• Research Category: Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
• Allocation Type: Multi-year Fund
• Review Section: Medium-sized Section 58:Society medicine, nursing, and related fields
• Research Institution: Oita University
• Principal Investigator: 山岡 吉生 大分大学, 医学部, 教授 (00544248)
• Co-Investigator(Kenkyū-buntansha): 松本 昂 大分大学, 医学部, 助教 (50609667) ; 矢原 耕史 国立感染症研究所, 薬剤耐性研究センター, 室長 (70542356)
• Project Period (FY): 2018-10-09 – 2024-03-31
• Project Status: Completed (Fiscal Year 2023)
• Budget Amount: ¥17,940,000 (Direct Cost: ¥13,800,000、Indirect Cost: ¥4,140,000); Fiscal Year 2021: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000); Fiscal Year 2020: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2019: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000); Fiscal Year 2018: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
• Keywords: ヘリコバクター・ピロリ / 胃癌 / 東アジア / アフリカ / 国際共同研究 / 遺伝子解析 / ベトナム / ブータン / モンゴル / 薬剤耐性 / 病原性 / テーラーメイド / テーラーメード

Outline of Annual Research Achievements

発展途上国では、ピロリ菌感染者すべてに除菌療法を行う経済力もなければ十分な内視鏡設備や内視鏡医も存在しない。ピロリ菌培養ができる施設も稀で、効果的な除菌療法も存在しない。そこで本研究では、アジアの発展途上国で胃癌多発国であるモンゴル、ブータン、ベトナムに焦点を当て、現地共同研究者と共同で、除菌を行うべき人および除菌法の選択に有用な未知の病原因子および薬剤耐性関連遺伝子の変異・多型の検索を、次世代シーケンサーを用いた菌側のゲノムワイド関連解析によって行う計画を立てた。最終的には、新規遺伝子解読技術（ナノポア）による、従来の内視鏡検査および細菌培養を必要としない迅速かつ非侵襲な病原因子および薬剤耐性関連遺伝子検出方法の開発に取り組むこととした。ブータンに関しては、地球規模課題対応国際科学技術協力プログラム（医療分野国際科学技術共同研究開発推進事業）(SATREPS) および 地球規模保健課題解決推進のための研究事業 (GACD)に採択され、これらの資金の活用も可能であったため、本研究では、東南アジア各国、さらにはアフリカ（コンゴ民主共和国）のピロリ菌解析に手を広げることも可能となり、各国での薬剤耐性関連遺伝子変異を検討することができ、またコンゴ民主共和国のピロリ菌には従来では稀なアモキシシリン耐性が多くみられること、さらにその原因となる遺伝子変異に関しても4か所の変異が関与していることを見出し、現在論文投稿中である。新型コロナウイルス感染禍も落ち着き、本年度は成果を海外で発表する機会も得た。米国消化器病週間（DDW）では、モンゴルからの留学生が口演発表、またアジア太平洋消化器病週間（APDW）では、代表者の山岡がマーシャル・ワレン賞を受賞（国内4名目）、インドネシアからの留学生が若手研究者賞（YIA）で1等賞、モンゴルからの留学生もYIA最終選考6名に選ばれた。

Research Products

• [Int'l Joint Research] ケサル・ギャルポ医科大学/ジグメ・ドルジ・ワンチュク 国立総合病院/保健省 王立疾病 管理センター(ブータン)
• [Int'l Joint Research] 108病院/チョーライ病院/ハノイ医科大学(ベトナム)
• [Int'l Joint Research] モンゴル国立医科学大学/モンゴル国立がん研究所(モンゴル)
• [Int'l Joint Research] ベイラー医科大学(米国)
• [Int'l Joint Research] キンシャサ大学(コンゴ民主共和国)
• [Int'l Joint Research] ケサル・ギャルポ医科大学/ジグメ・ドルジ・ワンチュク 国立総合病院/保健省 王立疾病 管理センター(ブータン)
• [Int'l Joint Research] 108病院/チョーライ病院/ハノイ医科大学(ベトナム)
• [Int'l Joint Research] モンゴル国立医科学大学/ウランバートル第3病院/モンゴル国立がん研究所(モンゴル)
• [Int'l Joint Research] ベイラー医科大学/ヒューストン大学ガルベストン 校(米国)
• [Int'l Joint Research] ブータン ケサール・ギャルポ 医科学大学/ジグメ・ドルジ・ワンチュク 国立総合病院/保健省 王立疾病 管理センター(ブータン)
• [Int'l Joint Research] 108病院/チョーライ病院/ハノイ医科大学(ベトナム)
• [Int'l Joint Research] モンゴル国立医科学大学/ウランバートル第3病院/モンゴル国立がん研究所(モンゴル)
• [Int'l Joint Research] ベイラー医科大学/ヒューストン大学ガルベストン校(米国)
• [Int'l Joint Research] ブータン王立医科大学(ブータン)
• [Int'l Joint Research] 108病院/チョーライ病院/ハノイ医科大学(ベトナム)
• [Int'l Joint Research] モンゴル国立医科学大学/ウランバートル第3病院/モンゴル国立がん研究所(モンゴル)
• [Int'l Joint Research] ベイラー医科大学/ヒューストン大学ガルベストン校(米国)
• [Int'l Joint Research] ワルダ大学(インド)
• [Int'l Joint Research] ブータン王立医科大学(ブータン)
• [Int'l Joint Research] 108病院/チョーライ病院/ハノイ医科大学(ベトナム)
• [Int'l Joint Research] モンゴル国立医科学大学/ウランバートル第3病院/モンゴル国立がん研究所(モンゴル)
• [Int'l Joint Research] ベイラー医科大学/テキサス大学ガルベストン 校(米国)
• [Int'l Joint Research] ワルダ大学(インド)
• [Int'l Joint Research]
• [Int'l Joint Research] ブータン王立医科大学(ブータン)
• [Int'l Joint Research] 108病院/チョーライ病院/ハノイ医科大学(ベトナム)
• [Int'l Joint Research] モンゴル国立医科学大学/ウランバートル第3病院/モンゴル国立がん研究所(モンゴル)
• [Int'l Joint Research] ベイラー医科大学/ヒューストン大学ガルベストン 校(米国)
• [Int'l Joint Research] ベンダ大学(南アフリカ)
• [Int'l Joint Research]
• [Journal Article] Primary antibiotic resistance of Helicobacter pylori in the Asia-Pacific region between 1990 and 2022: an updated systematic review and meta-analysis (2024)
  • Author(s): Hong Tzu-Chan、El-Omar Emad M、Kuo Yu-Ting、Wu Jeng-Yih、Chen Mei-Jyh、Chen Chieh-Chang、Fang Yu-Jen、Leow Alex Hwong Ruey、Lu Hong、Lin Jaw-Town、Tu Yu-Kang、Yamaoka Yoshio、Wu Ming-Shiang、Liou Jyh-Ming、Chen Yi-Chu、Chang Yung-Yueh
  • Journal Title: The Lancet Gastroenterology and Hepatology Volume: 9 Issue: 1 Pages: 56-67
  • DOI: 10.1016/s2468-1253(23)00281-9
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Simultaneous detection of Helicobacter pylori infection comparing between white light and image-enhanced endoscopy (2024)
  • Author(s): Chatrangsun Boonyaorn、Aumpan Natsuda、Pornthisarn Bubpha、Chonprasertsuk Soonthorn、Siramolpiwat Sith、Bhanthumkomol Patommatat、Nunanan Pongjarat、Issariyakulkarn Navapan、Mahachai Varocha、Yamaoka Yoshio、Vilaichone Ratha-korn
  • Journal Title: BMC Gastroenterology Volume: 24 Issue: 1 Pages: 46-46
  • DOI: 10.1186/s12876-024-03132-y
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Characterization of residual cancer by comparison of a pair of organoids established from a patient with esophageal squamous cell carcinoma before and after neoadjuvant chemotherapy (2024)
  • Author(s): Fuchino Takafumi、Kurogi Shusaku、Tsukamoto Yoshiyuki、Shibata Tomotaka、Fumoto Shoichi、Fujishima Hajime、Kinoshita Keisuke、Mizukami Kazuhiro、Kodama Masaaki、Inomata Masafumi、Murakami Kazunari、Moriyama Masatsugu、Hijiya Naoki
  • Journal Title: Human Cell Volume: 37 Issue: 2 Pages: 491-501
  • DOI: 10.1007/s13577-023-01020-3
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Study of Helicobacter pylori Isolated from a High-Gastric-Cancer-Risk Population: Unveiling the Comprehensive Analysis of Virulence-Associated Genes including Secretion Systems, and Genome-Wide Association Study (2023)
  • Author(s): Saruuljavkhlan B, Alfaray RI, Oyuntsetseg K, Gantuya B, Khangai A, Renchinsengee N, Matsumoto T, Akada J, Azzaya D, Davaadorj D, Yamaoka Y.
  • Journal Title: Cancers (Basel) Volume: 15 Issue: 18 Pages: 4528-4528
  • DOI: 10.3390/cancers15184528
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Predictive factors and prognosis of upper gastrointestinal bleeding in gastric cancer: A large population-based study (UGIB-GC trial) (2023)
  • Author(s): Kiattiweerasak Anya、Bongkotvirawan Phubordee、Aumpan Natsuda、Yamaoka Yoshio、Miftahussurur Muhammad、Vilaichone Ratha-korn
  • Journal Title: PLOS ONE Volume: 18 Issue: 9 Pages: e0291926-e0291926
  • DOI: 10.1371/journal.pone.0291926
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Utilization of an Automated Latex Agglutination Turbidity Assay for Assessing Gastric Mucosal Alteration during Helicobacter pylori Infection (2023)
  • Author(s): Khangai Ayush、Akada Junko、Saruuljavkhlan Batsaikhan、Gantuya Boldbaatar、Azzaya Dashdorj、Oyuntsetseg Khasag、Davaadorj Duger、Uchida Tomohisa、Matsumoto Takashi、Yamaoka Yoshio
  • Journal Title: Gut and Liver Volume: 18 Issue: 1 Pages: 60-69
  • DOI: 10.5009/gnl220464
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Global Antimicrobial Resistance Gene Study of Helicobacter pylori: Comparison of Detection Tools, ARG and Efflux Pump Gene Analysis, Worldwide Epidemiological Distribution, and Information Related to the Antimicrobial-Resistant Phenotype (2023)
  • Author(s): Alfaray Ricky Indra、Saruuljavkhlan Batsaikhan、Fauzia Kartika Afrida、Torres Roberto C.、Thorell Kaisa、Dewi Selva Rosyta、Kryukov Kirill A.、Matsumoto Takashi、Akada Junko、Vilaichone Ratha-korn、Miftahussurur Muhammad、Yamaoka Yoshio
  • Journal Title: Antibiotics Volume: 12 Issue: 7 Pages: 1118-1118
  • DOI: 10.3390/antibiotics12071118
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] A single-nucleotide polymorphism in Helicobacter pylori promotes gastric cancer development (2023)
  • Author(s): Sharafutdinov Irshad、Tegtmeyer Nicole、Linz Bodo、Rohde Manfred、Vieth Michael、Tay Alfred Chin-Yen、Lamichhane Binit、Tuan Vo Phuoc、Fauzia Kartika Afrida、Sticht Heinrich、Yamaoka Yoshio、Marshall Barry J.、Backert Steffen
  • Journal Title: Cell Host Microbe Volume: 31 Issue: 8 Pages: 1345-1358.e6
  • DOI: 10.1016/j.chom.2023.06.016
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Advantages of Whole Genome Sequencing in Mitigating the Helicobacter pylori Antimicrobial Resistance Problem (2023)
  • Author(s): Fauzia Kartika Afrida、Alfaray Ricky Indra、Yamaoka Yoshio
  • Journal Title: Microorganisms Volume: 11 Issue: 5 Pages: 1239-1239
  • DOI: 10.3390/microorganisms11051239
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Massive and Lengthy Clonal Nosocomial Expansion of Mycobacterium abscessus subsp. <i>massiliense</i> among Patients Who Are Ventilator Dependent without Cystic Fibrosis (2023)
  • Author(s): Komiya Kosaku、Yoshida Mitsunori、Uchida Sonoe、Takikawa Shuichi、Yamasue Mari、Matsumoto Takashi、Morishige Yuta、Aono Akio、Hiramatsu Kazufumi、Yamaoka Yoshio、Nishizono Akira、Ato Manabu、Kadota Jun-ichi、Mitarai Satoshi
  • Journal Title: Microbiology Spectrum Volume: 11 Issue: 4
  • DOI: 10.1128/spectrum.04908-22
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Genetic determinants of Biofilm formation of Helicobacter pylori using whole-genome sequencing (2023)
  • Author(s): Fauzia Kartika Afrida、Aftab Hafeza、Miftahussurur Muhammad、Waskito Langgeng Agung、Tuan Vo Phuoc、Alfaray Ricky Indra、Matsumoto Takashi、Yurugi Michiyuki、Subsomwong Phawinee、Kabamba Evariste Tshibangu、Akada Junko、Yamaoka Yoshio
  • Journal Title: BMC Microbiology Volume: 23 Issue: 1 Pages: 159-159
  • DOI: 10.1186/s12866-023-02889-8
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Comparative genomics of two Vietnamese Helicobacter pylori strains, CHC155 from a non-cardia gastric cancer patient and VN1291 from a duodenal ulcer patient. (2023)
  • Author(s): Phuc BH, Tuan VP, Binh TT, Tung PH, Tri TD, Dung HDQ, Thuan NPM, Fauzia KA, Tshibangu-Kabamba E, Alfaray RI, Saruuljavkhlan B, Matsumoto T, Akada J, Yamaoka Y.
  • Journal Title: Sci Rep Volume: 13 Issue: 1 Pages: 8869-8869
  • DOI: 10.1038/s41598-023-35527-4
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Management of dyspepsia and Helicobacter pylori infection: the 2022 Indonesian Consensus Report (2023)
  • Author(s): Syam Ari Fahrial、Miftahussurur Muhammad、Makmun Dadang、etc. Lucida Maria Inge、Rezkhita Yudith Annisa Ayu、Alfaray Ricky Indra、Yamaoka Yoshio
  • Journal Title: Gut Pathogens Volume: 15 Issue: 1 Pages: 25-25
  • DOI: 10.1186/s13099-023-00551-2
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Current management of corrosive, alcohol, and organophosphate poisoning: Pearls and pitfalls (2023)
  • Author(s): Miftahussurur Muhammad、Nabilah Nabilah、Rezkitha YudithAnnisa Ayu、Yamaoka Yoshio
  • Journal Title: Journal of Research in Medical Sciences Volume: 28 Issue: 1 Pages: 20-20
  • DOI: 10.4103/jrms.jrms_635_21
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Gastric microbiome changes in relation with Helicobacter pylori resistance (2023)
  • Author(s): Dewayani Astri、Afrida Fauzia Kartika、Alfaray Ricky Indra、Waskito Langgeng Agung、Doohan Dalla、Rejeki Purwo Sri、Alshawsh Mohammed Abdullah、Rezkitha Yudith Annisa Ayu、Yamaoka Yoshio、Miftahussurur Muhammad
  • Journal Title: PLOS ONE Volume: 18 Issue: 5 Pages: e0284958-e0284958
  • DOI: 10.1371/journal.pone.0284958
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Clinical significance of genetic polymorphisms of interleukin-1β and cytochrome P450 2C19 on the eradication of Helicobacter pylori (2023)
  • Author(s): Karbalaei Mohsen、Yamaoka Yoshio、Keikha Masoud
  • Journal Title: New Microbes and New Infections Volume: 53 Pages: 101131-101131
  • DOI: 10.1016/j.nmni.2023.101131
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] The interaction between autophagy, Helicobacter pylori, and gut microbiota in gastric carcinogenesis (2023)
  • Author(s): Nabavi-Rad Ali、Yadegar Abbas、Sadeghi Amir、Aghdaei Hamid Asadzadeh、Zali Mohammad Reza、Klionsky Daniel J.、Yamaoka Yoshio
  • Journal Title: Trends in Microbiology Volume: 31 Issue: 10 Pages: 1024-1043
  • DOI: 10.1016/j.tim.2023.04.001
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Hybrid, High-Dose Dual and Bismuth Quadruple Therapies for First-Line Treatment of Helicobacter pylori Infection in Taiwan: A Multicenter, Open-Label, Randomized Trial (2023)
  • Author(s): Hsu Ping-I、Chen Kuan-Yang、Tai Wei-Chen、Yang Jyh-Chin、Tsay Feng-Woei、Liu Yu-Hwa、Chen Chien-Lin、Lee Chia-Long、Yeh Hong-Zen、Kuo Chao-Hung、Chuah Seng-Kee、Lee Hsi-Chang、Shie Chang-Bih、Shiu Sz-Iuan、Kao John Y.、Yamaoka Yoshio、Graham David Y.、Wu Deng-Chyang
  • Journal Title: American Journal of Gastroenterology Volume: 118 Issue: 7 Pages: 1184-1195
  • DOI: 10.14309/ajg.0000000000002255
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Long-Term Resistance-Endurance Combined Training Reduces Pro-Inflammatory Cytokines in Young Adult Females with Obesity. (2023)
  • Author(s): Pranoto A, Cahyono MBA, Yakobus R, Izzatunnisa N, Ramadhan RN, Rejeki PS, Miftahussurur M, Effendi WI, Wungu CDK, Yamaoka Y.
  • Journal Title: Sports (Basel) Volume: 27 Issue: 3 Pages: 54-54
  • DOI: 10.3390/sports11030054
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Author Correction: Repeated out-of-Africa expansions of Helicobacter pylori driven by replacement of deleterious mutations (2023)
  • Author(s): Thorpe Harry A.、Tourrette Elise、Yahara Koji、Vale Filipa F.、Liu Siqi、Oleastro Monica、Alarcon Teresa、Perets Tsachi-Tsadok、Latifi-Navid Saeid、Yamaoka Yoshio、etc、Engstrand Lars、Agreus Lars、Suerbaum Sebastian、Thorell Kaisa、Falush Daniel
  • Journal Title: Nature Communications Volume: 14 Issue: 1 Pages: 1539-1539
  • DOI: 10.1038/s41467-023-37302-5
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Pattern and trends of Helicobacter pylori genotypes in gastric cancer: A Kenyan 8-year study. (2023)
  • Author(s): Njenga P, Njau A, Moloo Z, Revathi G, Tshibangu E, Yamaoka Y.
  • Journal Title: Front Med (Lausanne) Volume: 10 Pages: 1119513-1119513
  • DOI: 10.3389/fmed.2023.1119513
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] High levels of fecal calprotectin and C-reactive protein in patients with colitis. (2023)
  • Author(s): Anindita B, Sugihartono T, Miftahussurur M, Maimunah U, Nusi IA, Setiawan PB, Purbayu H, Kholili U, Widodo B, Thamrin H, Vidyani A, Rezkitha YAA, Yamaoka Y.
  • Journal Title: J Med Life. Volume: 16 Issue: 1 Pages: 48-51
  • DOI: 10.25122/jml-2021-0311
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Mutations Related to Antibiotics Resistance in Helicobacter pylori Clinical Isolates from Bangladesh. (2023)
  • Author(s): Fauzia, Kartika Afrida, Hafeza Aftab, Evariste Tshibangu-Kabamba, Ricky Indra Alfaray, Batsaikhan Saruuljavkhlan, Alain Cimuanga-Mukanya, Takashi Matsumoto, Phawinee Subsomwong, Junko Akada, Muhammad Miftahussurur, and Yoshio Yamaoka.
  • Journal Title: Antibiotics Volume: 12 Issue: 2 Pages: 279-279
  • DOI: 10.3390/antibiotics12020279
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Single 30 min treadmill exercise session suppresses the production of pro-inflammatory cytokines and oxidative stress in obese female adolescents. (2023)
  • Author(s): Pranoto Adi、Rejeki Purwo Sri、Miftahussurur Muhammad、Setiawan Hayuris Kinandita、Yosika Ghana Firsta、Munir Misbakhul、Maesaroh Siti、Purwoto Septyaningrum Putri、Waritsu Cakra、Yamaoka Yoshio.
  • Journal Title: Journal of Basic and Clinical Physiology and Pharmacology Volume: 34 Issue: 2 Pages: 235-242
  • DOI: 10.1515/jbcpp-2022-0196
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Low-grade intestinal metaplasia in Indonesia: Insights into the expression of proinflammatory cytokines during Helicobacter pylori infection and unique East-Asian CagA characteristics (2023)
  • Author(s): Miftahussurur Muhammad、Alfaray Ricky Indra、Fauzia Kartika Afrida、Dewayani Astri、Doohan Dalla、Waskito Langgeng Agung、Rezkitha Yudith Annisa Ayu、Utomo Didik Huswo、Somayana Gde、Fahrial Syam Ari、Lubis Masrul、Akada Junko、Matsumoto Takashi、Yamaoka Yoshio
  • Journal Title: Cytokine Volume: 163 Pages: 156122-156122
  • DOI: 10.1016/j.cyto.2022.156122
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] A comprehensive evaluation of an animal model for Helicobacter pylori‐associated stomach cancer: Fact and controversy. (2023)
  • Author(s): Amalia Rizki、Panenggak Nur Syahadati Retno、Doohan Dalla、Rezkitha Yudith Annisa Ayu、Waskito Langgeng Agung、Syam Ari Fahrial、Lubis Masrul、Yamaoka Yoshio、Miftahussurur Muhammad.
  • Journal Title: Helicobacter Volume: 28 Issue: 1
  • DOI: 10.1111/hel.12943
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Corrigendum: ‘Genome-wide association study of gastric cancer- and duodenal ulcer-derived Helicobacter pylori strains reveals discriminatory genetic variations and novel oncoprotein candidates’ (2023)
  • Author(s): Tuan Vo Phuoc、Yahara Koji、Dung Ho Dang Quy、Binh Tran Thanh、Tung Pham Huu、Tri Tran Dinh、Thuan Ngo Phuong Minh、Khien Vu Van、Trang Tran Thi Huyen、Phuc Bui Hoang、Tshibangu-Kabamba Evariste、Matsumoto Takashi、Akada Junko、Suzuki Rumiko、Okimoto Tadayoshi、etc. Kobayashi Ichizo、Yamaoka Yoshio
  • Journal Title: Microbial Genomics Volume: 9 Issue: 7
  • DOI: 10.1099/mgen.0.001062
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Exploring Alternative Treatment Choices for Multidrug-Resistant Clinical Strains of Helicobacter pylori in Mongolia (2023)
  • Author(s): Khangai Ayush、Saruuljavkhlan Batsaikhan、Azzaya Dashdorj、Gantuya Boldbaatar、Oyuntsetseg Khasag、Akada Junko、Matsumoto Takashi、Yamaoka Yoshio
  • Journal Title: Microorganisms Volume: 11 Issue: 12 Pages: 2852-2852
  • DOI: 10.3390/microorganisms11122852
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Antibiotic Resistance and Therapy for Helicobacter pylori Infection (2023)
  • Author(s): Smith Stella I.、Yamaoka Yoshio
  • Journal Title: Antibiotics Volume: 12 Issue: 12 Pages: 1669-1669
  • DOI: 10.3390/antibiotics12121669
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Management of Helicobacter pylori treatment failures: A large population-based study (HP treatment failures trial) (2023)
  • Author(s): Aumpan Natsuda、Issariyakulkarn Navapan、Mahachai Varocha、Graham David、Yamaoka Yoshio、Vilaichone Ratha-korn
  • Journal Title: PLOS ONE Volume: 18 Issue: 11 Pages: e0294403-e0294403
  • DOI: 10.1371/journal.pone.0294403
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Functional genome analysis and anti-Helicobacter pylori activity of a novel bacteriocinogenic Lactococcus sp. NH2-7C from Thai fermented pork (Nham) (2023)
  • Author(s): Kingkaew Engkarat、Woraprayote Weerapong、Booncharoen Auttaporn、Niwasabutra Kanidta、Janyaphisan Thitiphorn、Vilaichone Ratha-Korn、Yamaoka Yoshio、Visessanguan Wonnop、Tanasupawat Somboon
  • Journal Title: Scientific Reports Volume: 13 Issue: 1 Pages: 20362-20362
  • DOI: 10.1038/s41598-023-47687-4
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Pathogenomics of Helicobacter pylori (2023)
  • Author(s): Yamaoka Yoshio、Saruuljavkhlan Batsaikhan、Alfaray Ricky Indra、Linz Bodo
  • Journal Title: Curr Top Microbiol Immunol Volume: 444 Pages: 117-155
  • DOI: 10.1007/978-3-031-47331-9_5
  • ISBN: 9783031473302, 9783031473319
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] 日本国内より分離されたHelicobacter pylori の集団構造解析 (2023)
  • Author(s): 友成航平, Batsaikhan S, Alfaray RI, Fauzia KA, 松成修, 赤田純子, 松本昂, 珍田大輔, 下山克, 金城渚, 金城徹, 金城福則, 山岡吉生
  • Journal Title: 大分県医学会雑誌 Volume: 24 Pages: 100-108
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] インドネシアでの疫学調査その4 (2023)
  • Author(s): 山岡 吉生
  • Journal Title: Helicobacter Reserch Volume: 27-2 Pages: 81-92
  • Peer Reviewed
• [Journal Article] ドミニカ共和国での疫学調査その２ (2023)
  • Author(s): 山岡 吉生
  • Journal Title: Helicobacter Reserch Volume: 27-1 Pages: 111-125
  • Peer Reviewed
• [Journal Article] Novel Helicobacter pylori-associated hemolysis Hp0499 and Hp1490 and its association with severity of gastritis. (2023)
  • Author(s): Sang Ketut Widiana, Titong Sugihartono, Dalla Doohan, Langgeng Agung Waskito, Kartika Afrida Fauzia, Yudith Annisa Ayu Rezkitha, Adi Wasis Prakosa, Ricky Indra Alfaray, Camilia Metadea Aji Safitri, Rizki Amalia, Yoshio Yamaoka, Muhammad Miftahussurur.
  • Journal Title: F1000Research Volume: 12 Pages: 22-22
  • DOI: 10.12688/f1000research.122306.1
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] 日本国内より分離された?Helicobacter pylori の集団構造解析 (2023)
  • Author(s): 友成航平, Saruuljavkhlan Batsaikhan, Ricky Indra Alfaray, Kartika Afrida Fauzia1, 松成修, 赤田純子, 松本昂, 珍田大輔, 下山克, 金城渚, 金城徹, 金城福則, 山岡吉生
  • Journal Title: 大分県医学会雑誌 Volume: 29 Pages: 100-108
  • Peer Reviewed / Open Access
• [Journal Article] Cut-off value of clarithromycin resistance in the treatment of Helicobacter pylori infection: how low is low? (2022)
  • Author(s): Hsu Ping-I、Chuah Seng-Kee、Yamaoka Yoshio、Wu Deng-Chyang.
  • Journal Title: Gut Volume: online Issue: 2 Pages: 374-375
  • DOI: 10.1136/gutjnl-2022-329253
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Urease Levels and Gastritis Stage in Dyspeptic Patients. (2022)
  • Author(s): Miftahussurur M, Putri CDM, Sugihartono T, Syam AF, Purbayu H, Priyantini D, Kahar H, Rezkitha YAA, Nusi IA, Setiawan PB, Maimunah U, Waskito LA, Kholili U, Widodo B, Vidyani A, Thamrin H, Siregar GA, I'tishom R, Uchida T, Yamaoka Y.
  • Journal Title: Acta Med Indones Volume: 54 Pages: 42-51
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Seroepidemiological survey of the prevalence of Helicobacter pylori infection in Sabah, Malaysia (2022)
  • Author(s): Mori Daisuke、John Jecelyn Leaslie、Sabri Shahnaz Irwani Binti、Shaharom Saliz Mazrina Binti、Iha Hidekatsu、Yamaoka Yoshio、Matsumoto Takashi、Ahmed Kamruddin
  • Journal Title: IJID Regions Volume: 2 Pages: 126-129
  • DOI: 10.1016/j.ijregi.2021.12.012
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Helicobacter pylori cagA status and gastric mucosa-associated lymphoid tissue lymphoma: a systematic review and meta-analysis (2022)
  • Author(s): Keikha Masoud、Sahebkar Amirhossein、Yamaoka Yoshio、Karbalaei Mohsen
  • Journal Title: Journal of Health, Population and Nutrition Volume: 41 Issue: 1 Pages: 2-2
  • DOI: 10.1186/s41043-021-00280-9
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Next-Generation Sequencing-Based Study of Helicobacter pylori Isolates from Myanmar and Their Susceptibility to Antibiotics (2022)
  • Author(s): Subsomwong Phawinee、Doohan Dalla、Fauzia Kartika Afrida、Akada Junko、Matsumoto Takashi、Yee Than Than、Htet Kyaw、Waskito Langgeng Agung、Tuan Vo Phuoc、Uchida Tomohisa、Matsuhisa Takeshi、Yamaoka Yoshio
  • Journal Title: Microorganisms Volume: 10 Issue: 1 Pages: 196-196
  • DOI: 10.3390/microorganisms10010196
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Extragastric infection of Helicobacter pylori and alopecia areata: a systematic review and meta-analysis. (2022)
  • Author(s): Ghazvini Kiarash、Yamaoka Yoshio、Karbalaei Mohsen、Keikha Masoud.
  • Journal Title: Reviews in Medical Microbiology Volume: 33 Issue: 1 Pages: 114-118
  • DOI: 10.1097/mrm.0000000000000276
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Editorial: The Role of Mobile Genetic Elements in Bacterial Evolution and Their Adaptability (2022)
  • Author(s): Vale Filipa F.、Lehours Philippe、Yamaoka Yoshio
  • Journal Title: Frontiers in Microbiology Volume: 13 Pages: 1-2
  • DOI: 10.3389/fmicb.2022.849667
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Genomic differentiation within East Asian Helicobacter pylori (2022)
  • Author(s): You Yuanhai、Thorell Kaisa、He Lihua、Yahara Koji、Yamaoka Yoshio、Cha Jeong-Heon、Murakami Kazunari、Katsura Yukako、Kobayashi Ichizo、Falush Daniel、Zhang Jianzhong、TEAMHp
  • Journal Title: Microbial Genomics Volume: 8 Issue: 2 Pages: 1-14
  • DOI: 10.1099/mgen.0.000676
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Potassium intake is associated with nutritional quality and actual diet cost: a study at formulating a low sodium high potassium (LSHP) healthy diet (2022)
  • Author(s): Farapti Farapti、Buanasita Annas、Atmaka Dominikus R.、Setyaningtyas Stefania W.、Adriani Merryana、Rejeki Purwo S.、Yamaoka Yoshio、Miftahussurur Muhammad
  • Journal Title: Journal of Nutritional Science Volume: 11
  • DOI: 10.1017/jns.2021.104
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Unique TLR9 Activation by Helicobacter pylori Depends on the cag T4SS, But Not on VirD2 Relaxases or VirD4 Coupling Proteins (2022)
  • Author(s): Tegtmeyer Nicole、Linz Bodo、Yamaoka Yoshio、Backert Steffen
  • Journal Title: Current Microbiology Volume: 79 Issue: 4 Pages: 121-121
  • DOI: 10.1007/s00284-022-02813-9
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Effect of Nocturnal and Diurnal Moderate-intensity Swimming Exercise on Increasing Irisin Level of Female Mice (Mus musculus). (2022)
  • Author(s): Muhamad FA, Purwo SR, Sulistiawati, Adi P, Kristanti WW, Gadis MS, Ronny L, Yamaoka Y.
  • Journal Title: CMU J Nat Sci Volume: 21
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Review: Epidemiology of Helicobacter pylori Infection. (2022)
  • Author(s): Alfaray RI , Saruuljavkhlan B. Ansari S, Fauzia KA, Yamaoka Y.
  • Journal Title: Microb Health Dis (European Helicobacter & Microbiota Study Group) Volume: 4
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Helicobacter pylori genomes reveal Paleolithic human migration to the east end of Asia (2022)
  • Author(s): Suzuki Rumiko、Saitou Naruya、Matsuari Osamu、Shiota Seiji、Matsumoto Takashi、Akada Junko、Kinjo Nagisa、Kinjo Fukunori、Teruya Kuniko、Shimoji Makiko、Shiroma Akino、Kato Mototsugu、Satou Kazuhito、Hirano Takashi、Asaka Masahiro、Kryukov Kirill、Moodley Yoshan、Yamaoka Yoshio
  • Journal Title: iScience Volume: 25 Issue: 7 Pages: 104477-104477
  • DOI: 10.1016/j.isci.2022.104477
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] The role of non-Helicobacter pylori bacteria in the pathogenesis of gastroduodenal diseases. (2022)
  • Author(s): Waskito LA, Rezkitha YAA, Vilaichone RK, Sugihartono T, Mustika S, Dewa Nyoman Wibawa I, Yamaoka Y, Miftahussurur M.
  • Journal Title: Gut Pathog Volume: 14 Issue: 1 Pages: 19-19
  • DOI: 10.1186/s13099-022-00494-0
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Animal Models and Helicobacter pylori Infection. (2022)
  • Author(s): Ansari S, Yamaoka Y.
  • Journal Title: J Clin Med Volume: 11 Issue: 11 Pages: 3141-3141
  • DOI: 10.3390/jcm11113141
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Macronutrient and micronutrient intake in dietary habits contributed to dyspeptic symptoms in Indonesia. (2022)
  • Author(s): Miftahussurur M., Alfaray R.I., Rezkitha Y.A.A., Fauzia K.A., Maulahela H., Muzellina V.N., Rotty L.S.M., Namara Y.S., Abubakar A., Mustika S., Ratnasari N., Santosa A.Y., Richardo M., Wibawa I.D.N., Adnyana I.K., Rachman P.H., Rachman B.E., Doohan D., Waskito L.A., Yamaoka Y., Khomsan A.
  • Journal Title: Gaceta Medica de Caracas Volume: 130 Issue: 2 Pages: 266-275
  • DOI: 10.47307/gmc.2022.130.2.6
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Role of fecal calprotectin as a hypoxic intestinal damage biomarker in COVID-19 patients. (2022)
  • Author(s): Adriana DN, Sugihartono T, Nusi IA, Setiawan PB, Purbayu H, Maimunah U, Kholili U, Widodo B, Thamrin H, Vidyani A, Maulahela H, Yamaoka Y, Miftahussurur M.
  • Journal Title: Gut Pathog Volume: 14 Issue: 1 Pages: 34-34
  • DOI: 10.1186/s13099-022-00507-y
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Analysis of gastric microbiota and Helicobacter pylori infection in gastroesophageal reflux disease (2022)
  • Author(s): Sugihartono Titong、Fauzia Kartika Afrida、Miftahussurur Muhammad、Waskito Langgeng Agung、Rejeki Purwo Sri、I’tishom Reny、Alfaray Ricky Indra、Doohan Dalla、Amalia Rizki、Savitri Camilia Metadea Aji、Rezkitha Yudith Annisa Ayu、Akada Junko、Matsumoto Takashi、Yamaoka Yoshio
  • Journal Title: Gut Pathogens Volume: 14 Issue: 1 Pages: 38-38
  • DOI: 10.1186/s13099-022-00510-3
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Helicobacter pylori Infection, Its Laboratory Diagnosis, and Antimicrobial Resistance: a Perspective of Clinical Relevance. (2022)
  • Author(s): Ansari S, Yamaoka Y.
  • Journal Title: Clin Microbiol Rev Volume: 35 Issue: 3
  • DOI: 10.1128/cmr.00258-21
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Helicobacter pylori infection: is there circulating vacuolating cytotoxin A or cytotoxin-associated gene A protein? (2022)
  • Author(s): Imoto I, Oka S, Katsurahara M, Nakamura M, Yasuma T, Akada J, D'Alessandro-Gabazza CN, Toda M, Horiki N, Gabazza EC, Yamaoka Y.
  • Journal Title: Gut Pathog Volume: 14 Issue: 1 Pages: 43-43
  • DOI: 10.1186/s13099-022-00519-8
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Helicobacter pylori prevalence in Indonesia: Higher infection risk in Eastern region population. (2022)
  • Author(s): Maulahela H, Doohan D, Annisa Ayu Rezkhita Y, Syam AF, Waskito LA, Metadea Aji Savitri C, Richardo M, Rahman A, Namara YS, Shatri H, Sanityoso A, Alamsyah. Siregar G, Sudarmo E, Uchida T, Vilaichone RK, Yamaoka Y, Muhammad Miftahussurur.
  • Journal Title: F1000Research Volume: 11
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] 第25回 マレーシアでの疫学調査 (2022)
  • Author(s): 山岡吉生
  • Journal Title: Helicobacter Research Volume: 26 Pages: 95-106
• [Journal Article] 35th Workshop of the European Helicobacter and Microbiota Study Group (EHMSG) 2022 (2022年9月8～10日, グラスゴー) (2022)
  • Author(s): 山岡吉生
  • Journal Title: Helicobacter Research Volume: 26 Pages: 226-229
• [Journal Article] 第26回 ドミニカ共和国での疫学調査 その1 (2022)
  • Author(s): 山岡吉生
  • Journal Title: Helicobacter Research Volume: 26 Pages: 233-242
• [Journal Article] Repeated out-of-Africa expansions of Helicobacter pylori driven by replacement of deleterious mutations. (2022)
  • Author(s): Thorpe HA, Tourrette E, Yahara K, Vale FF, Liu S, Oleastro M, Alarcon T. Perets TT, Latifi-Navid S, Yamaoka Y, Martinez-Gonzalez B, Karayiannis I, Karamitros T, Sgouras DN, Elamin W, Pascoe B, Sheppard SK, Ronkainen J, Aro P, Engstrand L, Agreus L, Suerbaum S, Thorell K, Falush D.
  • Journal Title: Nature Communications Volume: 13 Issue: 1 Pages: 6842-6842
  • DOI: 10.1038/s41467-022-34475-3
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Clinical manifestations of COVID-19 in patients with asthma, hypertension, and diabetes mellitus. (2022)
  • Author(s): Budiarti R, Ediono E, Kalaznykov M, Yamaoka Y, Miftahussurur M.
  • Journal Title: Journal of Medicine and Life Volume: 15 Issue: 12 Pages: 1502-1506
  • DOI: 10.25122/jml-2021-0364
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Serum pepsinogen level as a biomarker for atrophy, reflux esophagitis, and gastric cancer screening in Indonesia. (2022)
  • Author(s): Miftahussurur M, Waskito LA, Syam AF, Nusi IA, Wibawa IDN, Rezkitha YAA, Fauzia KA, Siregar GA, Akil F, Waleleng BJ, Saudale AMJ, Abubakar A, Maulahela H, Richardo M, Rahman A, Namara YS, Sudarmo E, Adi P, Maimunah U, Setiawan, Yamaoka Y.
  • Journal Title: Journal of Research in Medical Sciences Volume: 27 Issue: 1 Pages: 90-90
  • DOI: 10.4103/jrms.jrms_983_21
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Urease Levels and Gastritis Stage in Dyspeptic Patients (2022)
  • Author(s): Miftahussurur M, Putri CDM, Sugihartono T, Syam AF, Purbayu H, Priyantini D, Kahar H, Rezkitha YAA, Nusi IA, Setiawan PB, Maimunah U, Waskito LA, Kholili U, Widodo B, Vidyani A, Thamrin H, Siregar GA, I'tishom R, Uchida T, Yamaoka Y.
  • Journal Title: Acta Med Indones Volume: 54 Pages: 42-51
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Characterization of Helicobacter pylori tlyA and Its Association with Bacterial Density (2021)
  • Author(s): Prakosa Adi Wasis、Miftahussurur Muhammad、Juniastuti Juniastuti、Waskito Langgeng Agung、Doohan Dalla、Fauzia Kartika Afrida、Rezkitha Yudith Annisa Ayu、Sugihartono Titong、Syam Ari Fahrial、Uchida Tomohisa、Yamaoka Yoshio
  • Journal Title: Digestive Diseases Volume: Online ahead of print Issue: 4 Pages: 417-426
  • DOI: 10.1159/000518538
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] The effect of long-term ketogenic diet on serum adiponectin and insulin-like growth factor-1 levels in mice (2021)
  • Author(s): Widiatmaja Deandra M.、Lutvyani Alif、Sari Desi R.、Kurniasari Hamidah、Meiliana Ismi D.、Fasitasari Minidian、Yamaoka Yoshio、Rejeki Purwo S.
  • Journal Title: Journal of Basic and Clinical Physiology and Pharmacology Volume: 1 Issue: 5 Pages: 1-10
  • DOI: 10.1515/jbcpp-2021-0287
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Genome-wide association study of gastric cancer- and duodenal ulcer-derived Helicobacter pylori strains reveals discriminatory genetic variations and novel oncoprotein candidates (2021)
  • Author(s): Tuan V P、Yahara K、Dung H D Q、Binh T T、Huu T P、Tri T D、Thuan N P M、Khien V V、Trang T T H、Phuc B H、Tshibangu-Kabamba E、Matsumoto T、Akada J、Suzuki R、Okimoto T、Kodama M、Murakami K、Yano H、Fukuyo M、Takahashi N、Kato M、Nishiumi S、Azuma T、Ogura Y、Hayashi T、Toyoda A、Kobayashi I、Yamaoka Y
  • Journal Title: Microbial Genomics Volume: 7 Issue: 11 Pages: 1-17
  • DOI: 10.1099/mgen.0.000680
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Gastric epithelial attachment of Helicobacter pylori induces EphA2 and NMHC‐IIA receptors for Epstein‐Barr virus (2021)
  • Author(s): Fekadu Sintayehu、Kanehiro Yuichi、Kartika Andy Visi、Hamada Kazuki、Sakurai Nozomi、Mizote Tomoko、Akada Junko、Yamaoka Yoshio、Iizasa Hisashi、Yoshiyama Hironori
  • Journal Title: Cancer Science Volume: 112 Issue: 11 Pages: 4799-4811
  • DOI: 10.1111/cas.15121
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Assessment of the diagnostic accuracy and relevance of a novel ELISA system developed for seroepidemiologic surveys of Helicobacter pylori infection in African settings (2021)
  • Author(s): Tshibangu-Kabamba Evariste、Phuc Bui Hoang、Tuan Vo Phuoc、Kayiba Nadine Kalenda、Rosas-Aguirre Angel、Devleesschauwer Brecht、Cimuanga-Mukanya Alain、Ngoma Kisoko Patrick de Jsus、Disashi Ghislain Tumba、Mumba Ngoyi Dieudonn、Kido Yasutoshi、Speybroeck Niko、Yamaoka Yoshio
  • Journal Title: PLOS Neglected Tropical Diseases Volume: 15 Issue: 9 Pages: e0009763-e0009763
  • DOI: 10.1371/journal.pntd.0009763
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Helicobacter pylori infection and antibiotic resistance ? from biology to clinical implications (2021)
  • Author(s): Tshibangu-Kabamba Evariste、Yamaoka Yoshio
  • Journal Title: Nature Reviews Gastroenterology &amp; Hepatology Volume: 18 Issue: 9 Pages: 613-629
  • DOI: 10.1038/s41575-021-00449-x
  • Peer Reviewed
• [Journal Article] Predictors for regression and progression of intestinal metaplasia (IM): A large population-based study from low prevalence area of gastric cancer (IM-predictor trial) (2021)
  • Author(s): Aumpan Natsuda、Vilaichone Ratha-korn、Pornthisarn Bubpha、Chonprasertsuk Soonthorn、Siramolpiwat Sith、Bhanthumkomol Patommatat、Nunanan Pongjarat、Issariyakulkarn Navapan、Ratana-Amornpin Sarita、Miftahussurur Muhammad、Mahachai Varocha、Yamaoka Yoshio
  • Journal Title: PLOS ONE Volume: 16 Issue: 8 Pages: e0255601-e0255601
  • DOI: 10.1371/journal.pone.0255601
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Serum Helicobacter pylori antibody reactivity in seven Asian countries using an automated latex aggregation turbidity assay (2021)
  • Author(s): Akada J,Tshibangu‐K,Tuan V,Kurogi S,Matsuo Y,Ansari S,Doohan D,Phuc B,Subsomwong P,Waskito L,Binh T,Nguyen L,Khien V,Dung H,Miftahussurur M,Syam A,Tshering L,Vilaichone R,Mahachai V,Ratanachu‐ek T,Shrestha P,Yee T,Htet K,Aftab H,Matsuhisa T,Uchida T,Okimoto T,Mizukami K,Kodama M,Murakami K,Takahashi N,Yamaoka Yoshio
  • Journal Title: Journal of Gastroenterology and Hepatology Volume: - Issue: 8 Pages: 1-10
  • DOI: 10.1111/jgh.15467
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Pepsinogen and Serum IgG Detection Is a Valuable Diagnostic Method for Helicobacter pylori Infection in a Low-Prevalence Country: A Report from Sri Lanka (2021)
  • Author(s): Doohan Dalla、Fauzia Kartika Afrida、Rathnayake Jeewantha、Lamawansa Meegahalande Durage、Waskito Langgeng Agung、Tuan Vo Phuoc、Dashdorj Azzaya、Kabamba Evariste Tshibangu、Phuc Bui Hoang、Ansari Shamshul、Akada Junko、Matsumoto Takashi、Uchida Tomohisa、Matsuhisa Takeshi、Yamaoka Yoshio
  • Journal Title: Diagnostics Volume: 11 Issue: 8 Pages: 1364-1364
  • DOI: 10.3390/diagnostics11081364
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Benefits of a Molecular-Based Method for the Detection of Clarithromycin-Resistant <i>Helicobacter pylori</i> (2021)
  • Author(s): Saruuljavkhlan Batsaikhan、Yamaoka Yoshio
  • Journal Title: Gut and Liver Volume: 15 Issue: 4 Pages: 487-489
  • DOI: 10.5009/gnl210278
  • Peer Reviewed / Open Access
• [Journal Article] Helicobacter pylori BabA?SabA Key Roles in the Adherence Phase: The Synergic Mechanism for Successful Colonization and Disease Development (2021)
  • Author(s): Doohan Dalla、Rezkitha Yudith Annisa Ayu、Waskito Langgeng Agung、Yamaoka Yoshio、Miftahussurur Muhammad
  • Journal Title: Toxins Volume: 13 Issue: 7 Pages: 485-485
  • DOI: 10.3390/toxins13070485
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Diagnostic Value of 14C Urea Breath Test for Helicobacter pylori Detection Compared by Histopathology in Indonesian Dyspeptic Patients (2021)
  • Author(s): Miftahussurur M、Windia A、Syam AF、Nusi IA、Alfaray RI、Fauzia KA、Kahar H、Purbayu H、 Sugihartono T、Setiawan PB、Maimunah U、Kholili U、Thamrin H、Vidyani A、Doohan D、Waskito LA、Rezkitha YAA、Siregar GA、Yamaoka Yoshio
  • Journal Title: Clinical and Experimental Gastroenterology Volume: Volume 14 Pages: 291-296
  • DOI: 10.2147/ceg.s306626
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Helicobacter pylori in the Indonesian Malay’s descendants might be imported from other ethnicities (2021)
  • Author(s): Syam Ari Fahrial、Waskito Langgeng Agung、Rezkitha Yudith Annisa Ayu、Simamora Rentha Monica、Yusuf Fauzi、Danchi Kanserina Esthera、Bakry Ahmad Fuad、Arnelis、Mulya Erwin、Siregar Gontar Alamsyah、Sugihartono Titong、Maulahela Hasan、Doohan Dalla、Miftahussurur Muhammad、Yamaoka Yoshio
  • Journal Title: Gut Pathogens Volume: 13 Issue: 1 Pages: 36-36
  • DOI: 10.1186/s13099-021-00432-6
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Inhibition of low-density lipoprotein uptake by Helicobacter pylori virulence factor CagA. (2021)
  • Author(s): Ninomiya R, Kubo S, Baba T, Kajiwara T, Tokunaga A, Nabeka H, Doihara T, Shimokawa T, Matsuda S, Murakami K, Aigaki T, Yamaoka Y, Hamada F.
  • Journal Title: Biochem Biophys Res Commun. Volume: 556 Pages: 192-198
  • DOI: 10.1016/j.bbrc.2021.03.170
  • Peer Reviewed
• [Journal Article] Advantage of 16S rRNA amplicon sequencing in Helicobacter pylori diagnosis (2021)
  • Author(s): Gantuya Boldbaatar、El Serag Hashem B.、Saruuljavkhlan Batsaikhan、Azzaya Dashdorj、Matsumoto Takashi、Uchida Tomohisa、Oyuntsetseg Khasag、Oyunbileg Nyamdorj、Davaadorj Duger、Yamaoka Yoshio
  • Journal Title: Helicobacter Volume: - Issue: 3
  • DOI: 10.1111/hel.12790
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] The Roles of IL-17, IL-21, and IL-23 in the Helicobacter pylori Infection and Gastrointestinal Inflammation: A Review (2021)
  • Author(s): Dewayani Astri、Fauzia Kartika Afrida、Alfaray Ricky Indra、Waskito Langgeng Agung、Doohan Dalla、Rezkitha Yudith Annisa Ayu、Abdurachman Abdurachman、Kobayashi Takashi、I’tishom Reny、Yamaoka Yoshio、Miftahussurur Muhammad
  • Journal Title: Toxins Volume: 13 Issue: 5 Pages: 315-315
  • DOI: 10.3390/toxins13050315
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] A bacterial small RNA regulates the adaptation of Helicobacter pylori to the host environment (2021)
  • Author(s): Kinoshita-Daitoku, R., Kiga, K., Miyakoshi, M. et al.
  • Journal Title: Nature Communications Volume: 12 Issue: 1 Pages: 2085-2085
  • DOI: 10.1038/s41467-021-22317-7
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] CYP2C19 Polymorphisms in Indonesia: Comparison among Ethnicities and the Association with Clinical Outcomes (2021)
  • Author(s): Miftahussurur M、Doohan D、Syam AF、Nusi IA、Subsomwong P、Waskito LA、Maulahela H、Akil F、 Uwan WB、Siregar G、Fauzia KA、Rezkitha YAA、Rahman A、Wibawa IDN、Saudale AMJ、Richardo M、 Sugihartono T、Chomariyati A、Bramantoro T、Uchida T、Yamaoka Yoshio
  • Journal Title: Biology Volume: 10 Issue: 4 Pages: 300-300
  • DOI: 10.3390/biology10040300
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Spatial and molecular mapping of Pfkelch13 gene polymorphism in Africa in the era of emerging Plasmodium falciparum resistance to artemisinin: a systematic review (2021)
  • Author(s): Kayiba Nadine K、Yobi Doudou M、Tshibangu-Kabamba Evariste、Tuan Vo P、Yamaoka Yoshio、 Devleesschauwer Brecht、Mvumbi Dieudonn? M、Okitolonda Wemakoy Emile、De Mol Patrick、Mvumbi Georges L、Hayette Marie-Pierre、Rosas-Aguirre Angel、Speybroeck Niko
  • Journal Title: The Lancet Infectious Diseases Volume: 21 Issue: 4 Pages: e82-e92
  • DOI: 10.1016/s1473-3099(20)30493-x
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Integrating microbiome, transcriptome and metabolome data to investigate gastric disease pathogenesis: a concise review (2021)
  • Author(s): Doohan Dalla、Rezkitha Yudith Annisa Ayu、Waskito Langgeng Agung、Vilaichone Ratha-korn、Yamaoka Yoshio、Miftahussurur Muhammad
  • Journal Title: Expert Reviews in Molecular Medicine Volume: 23 Pages: 1-10
  • DOI: 10.1017/erm.2021.8
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Gastroesophageal Reflux Disease: Facts and Myths (2021)
  • Author(s): Sugihartono, T., Miftahussurur, M., Simamora, R.M., Kuntaman, K., Rezkitha, Y.A.A., Yamaoka, Y
  • Journal Title: Journal of International Dental and Medical Research Volume: 14 Pages: 865-874
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] 海外Helicobacter pylori疫学調査-立案,調査からデータ解析に至るまで-第24回 ネパール連邦民主共和国 (2021)
  • Author(s): 山岡吉生
  • Journal Title: Helicobacter Research Volume: 25 Pages: 231-241
  • NAID: 40022765344
• [Journal Article] 海外Helicobacter pylori疫学調査-立案,調査からデータ解析に至るまで-第23回 カンボジア王国での疫学調査 (2021)
  • Author(s): 山岡吉生
  • Journal Title: Helicobacter Research Volume: 25 Pages: 97-105
  • NAID: 40022632223
• [Journal Article] 【消化管がん検診・スクリーニングの手引き】(第II章)消化管がんの疫学 日本・世界におけるHelicobacter pylori感染の動向 (2021)
  • Author(s): 山岡 吉生
  • Journal Title: 臨床消化器内科 Volume: 36 Pages: 853-858
• [Journal Article] Helicobacter pylori type 4 secretion systems as gastroduodenal disease markers (2021)
  • Author(s): Phuc Bui Hoang、Tuan Vo Phuoc、Dung Ho Dang Quy、Binh Tran Thanh、Tung Pham Huu、Tri Tran Dinh、Thuan Ngo Phuong Minh、Van Khien Vu、Trang Tran Thi Huyen、Akada Junko、Matsumoto Takeshi、Yamaoka Yoshio
  • Journal Title: Scientific Reports Volume: 11 Issue: 1 Pages: 4584-4584
  • DOI: 10.1038/s41598-021-83862-1
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Discovery of unique African Helicobacter pylori CagA-multimerization motif in the Dominican Republic (2020)
  • Author(s): Ono Takaaki、Cruz Modesto、Nagashima Hiroyuki、Subsomwong Phawinee、Akada Junko、Matsumoto Takashi、Uchida Tomohisa、Suzuki Rumiko、Hosking Celso、Abreu Jos? A Jim?nez、Yamaoka Yoshio
  • Journal Title: World Journal of Gastroenterology Volume: 26 Issue: 45 Pages: 7118-7130
  • DOI: 10.3748/wjg.v26.i45.7118
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Helicobacter pylori Virulence Factor Cytotoxin-Associated Gene A (CagA)-Mediated Gastric Pathogenicity (2020)
  • Author(s): Ansari Shamshul、Yamaoka Yoshio
  • Journal Title: International Journal of Molecular Sciences Volume: 21 Issue: 19 Pages: 7430-7430
  • DOI: 10.3390/ijms21197430
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Screening and eradication of Helicobacter pylori for gastric cancer prevention: the Taipei global consensus (2020)
  • Author(s): Liou JM、Malfertheiner P、Lee YC、Sheu BS、Sugano K、Cheng HC、Yeoh KG、Hsu PI、Goh KL、Mahachai V、Gotoda T、Chang WL、Chen MJ、Chiang TH、Chen CC、Wu CY、Leow AHR、Wu JY、Wu DC、Hong TC、Lu H、Yamaoka Yoshio、Megraud F、Chan FKL、Sung JJY、Lin JT、Graham DY、Wu MS、El-Omar EM
  • Journal Title: Gut Volume: 69 Issue: 12 Pages: 2093-2112
  • DOI: 10.1136/gutjnl-2020-322368
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Predictors for development of complete and incomplete intestinal metaplasia (IM) associated with H. pylori infection: A large-scale study from low prevalence area of gastric cancer (IM-HP trial) (2020)
  • Author(s): Aumpan Natsuda、Vilaichone Ratha-Korn、Nunanan Pongjarat、Chonprasertsuk Soonthorn、Siramolpiwat Sith、Bhanthumkomol Patommatat、Pornthisarn Bubpha、Uchida Tomohisa、Vilaichone Virunpat、Wongcha-Um Arti、Yamaoka Yoshio、Mahachai Varocha
  • Journal Title: PLOS ONE Volume: 15 Issue: 10 Pages: e0239434-e0239434
  • DOI: 10.1371/journal.pone.0239434
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] The Potential Benefits of Vonoprazan as Helicobacter pylori Infection Therapy (2020)
  • Author(s): Miftahussurur Muhammad、Pratama Putra Boby、Yamaoka Yoshio
  • Journal Title: Pharmaceuticals Volume: 13 Issue: 10 Pages: 276-276
  • DOI: 10.3390/ph13100276
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Whole Genome Sequencing Reveals Virulence Potentials of Helicobacter pylori Strain KE21 Isolated from a Kenyan Patient with Gastric Signet Ring Cell Carcinoma (2020)
  • Author(s): Mwangi Catherine、Njoroge Stephen、Tshibangu-Kabamba Evariste、Moloo Zahir、Rajula Allan、Devani Smita、Matsumoto Takashi、Nyerere Kimang’a、Kariuki Samuel、Revathi Gunturu、Yamaoka Yoshio
  • Journal Title: Toxins Volume: 12 Issue: 9 Pages: 556-556
  • DOI: 10.3390/toxins12090556
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Gut-Homing CD4+ T Cells Are Associated with the Activity of Gastritis in HIV-Infected Adults (2020)
  • Author(s): Sato Hidenori、Ota Yasunori、Kido Yasutoshi、Matsumoto Takashi、Matsubara Yasuo、Matano Tetsuro、Hirata Yoshihiro、Kawana-Tachikawa Ai、Yamaoka Yoshio、Yotsuyanagi Hiroshi、Adachi Eisuke
  • Journal Title: AIDS Research and Human Retroviruses Volume: 36 Issue: 11 Pages: 910-917
  • DOI: 10.1089/aid.2020.0086
  • Peer Reviewed
• [Journal Article] The validation of the Helicobacter pylori CagA typing by immunohistochemistry: nationwide application in Indonesia (2020)
  • Author(s): Miftahussurur Muhammad、Doohan Dalla、Syam Ari Fahrial、Nusi Iswan Abbas、Waskito Langgeng Agung、Fauzia Kartika Afrida、Rezkitha Yudith Annisa Ayu、Dewayani Astri、I'tishom Reny、Maulahela Hasan、Uchida Tomohisa、Yamaoka Yoshio
  • Journal Title: Acta Histochemica Volume: 122 Issue: 6 Pages: 151594-151594
  • DOI: 10.1016/j.acthis.2020.151594
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] High Antibiotic Resistance of Helicobacter pylori and Its Associated Novel Gene Mutations among the Mongolian Population (2020)
  • Author(s): Azzaya Dashdorj、Gantuya Boldbaatar、Oyuntsetseg Khasag、Davaadorj Duger、Matsumoto Takashi、Akada Junko、Yamaoka Yoshio
  • Journal Title: Microorganisms Volume: 8 Issue: 7 Pages: 1062-1062
  • DOI: 10.3390/microorganisms8071062
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Role of vacuolating cytotoxin A in Helicobacter pylori infection and its impact on gastric pathogenesis (2020)
  • Author(s): Ansari Shamshul、Yamaoka Yoshio
  • Journal Title: Expert Review of Anti-infective Therapy Volume: 18 Issue: 10 Pages: 987-996
  • DOI: 10.1080/14787210.2020.1782739
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Next-Generation Sequencing of the Whole Bacterial Genome for Tracking Molecular Insight into the Broad-Spectrum Antimicrobial Resistance of Helicobacter pylori Clinical Isolates from the Democratic Republic of Congo (2020)
  • Author(s): Tshibangu-Kabamba Evariste、Ngoma-Kisoko Patrick de Jesus、Tuan Vo Phuoc、Matsumoto Takashi、Akada Junko、Kido Yasutoshi、Tshimpi-Wola Antoine、Tshiamala-Kashala Pascal、Ahuka-Mundeke Steve、Mumba Ngoy Dieudonn?、Disashi-Tumba Ghislain、Yamaoka Yoshio
  • Journal Title: Microorganisms Volume: 8 Issue: 6 Pages: 887-887
  • DOI: 10.3390/microorganisms8060887
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Letter: are microbes other than Helicobacter pylori associated with gastric cancer? Authors' reply (2020)
  • Author(s): Gantuya Boldbaatar、El-Serag Hashem B.、Yamaoka Yoshio
  • Journal Title: Alimentary Pharmacology & Therapeutics Volume: 51 Issue: 12 Pages: 1447-1449
  • DOI: 10.1111/apt.15757
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Population-based study of Helicobacter pylori infection and antibiotic resistance in Bhutan (2020)
  • Author(s): Vilaichone Ratha-korn、Aumpan Natsuda、Ratanachu-ek Thawee、Uchida Tomohisa、Tshering Lotay、Mahachai Varocha、Yamaoka Yoshio
  • Journal Title: International Journal of Infectious Diseases Volume: 97 Pages: 102-107
  • DOI: 10.1016/j.ijid.2020.05.077
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Gastric microbiota and Helicobacter pylori in Indonesian population (2020)
  • Author(s): Miftahussurur Muhammad、Waskito Langgeng Agung、El‐Serag Hashem B、Ajami Nadim J.、Nusi Iswan Abbas、Syam Ari Fahrial、Matsumoto Takashi、Rezkitha Yudith Annisa Ayu、Doohan Dalla、Fauzia Kartika Afrida、Maimunah Ummi、Sugihartono Titong、Uchida Tomohisa、Yamaoka Yoshio
  • Journal Title: Helicobacter Volume: 25 Issue: 4
  • DOI: 10.1111/hel.12695
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Prevalence and Antibiotic Resistance Patterns of Helicobacter pylori Infection in Koh Kong, Cambodia (2020)
  • Author(s): Aumpan Natsuda、Vilaichone Ratha-Korn、Gamnarai Pornpen、Sanglutong Likhasit、Ratanachu-ek Thawee、Mahachai Varocha、Yamaoka Yoshio
  • Journal Title: Asian Pacific Journal of Cancer Prevention Volume: 21 Issue: 5 Pages: 1409-1413
  • DOI: 10.31557/apjcp.2020.21.5.1409
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Differences in efficacy and safety of lubiprostone used for idiopathic vs. opioid-induced constipation: Meta-analysis of East Asian and Western Populations (2020)
  • Author(s): Sugimoto M, Murata T, Mizuno H
  • Journal Title: J Clin Biochem Nutr Volume: 66 Issue: 15 Pages: 184-192
  • DOI: 10.3748/wjg.v26.i15.1820
  • NAID: 130007839284
  • Peer Reviewed / Open Access
• [Journal Article] Serum pepsinogens as a gastric cancer and gastritis biomarker in South and Southeast Asian populations (2020)
  • Author(s): Miftahussurur Muhammad、Waskito Langgeng Agung、Aftab Hafeza、Vilaichone Ratha-korn、Subsomwong Phawinee、Nusi Iswan Abbas、Syam Ari Fahrial、Ratanachu-ek Thawee、Doohan Dalla、Siregar Gontar、Rezkitha Yudith Annisa Ayu、Fauzia Kartika Afrida、Mahachai Varocha、Yamaoka Yoshio
  • Journal Title: PLOS ONE Volume: 15 Issue: 4 Pages: e0230064-e0230064
  • DOI: 10.1371/journal.pone.0230064
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Efficacy of Omeprazole, Tetracycline, and 4 Times Daily Dosing of Amoxicillin in Helicobacter pylori Eradication in Limited Resource Area in Bhutan: A Prospective Randomized Trial (BHUTAN Study) (2020)
  • Author(s): Vilaichone Ratha-Korn、Aumpan Natsuda、Ratanachu-ek Thawee、Gamnarai Pornpen、Uchida Tomahisa、Tshering Lotay、Mahachai Varocha、Yamaoka Yoshio
  • Journal Title: Asian Pacific Journal of Cancer Prevention Volume: 21 Issue: 4 Pages: 1109-1114
  • DOI: 10.31557/apjcp.2020.21.4.1109
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Gastric mucosal microbiota in a Mongolian population with gastric cancer and precursor conditions (2020)
  • Author(s): Gantuya Boldbaatar、El Serag Hashem B.、Matsumoto Takashi、Ajami Nadim J.、Uchida Tomohisa、Oyuntsetseg Khasag、Bolor Dashdorj、Yamaoka Yoshio
  • Journal Title: Alimentary Pharmacology & Therapeutics Volume: 51 Issue: 8 Pages: 770-780
  • DOI: 10.1111/apt.15675
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] 海外Helicobacter pylori疫学調査 : 立案,調査からデータ解析に至るまで(第21回)アフリカでの疫学調査(その3)ルワンダ共和国およびケニア共和国 (2020)
  • Author(s): 山岡 吉生
  • Journal Title: Helicobacter research Volume: 24 Pages: 211-219
  • NAID: 40022256131
• [Journal Article] H.pylori遺伝子解析による人類の起源について (2020)
  • Author(s): 山岡 吉生
  • Journal Title: The GI Forefront Volume: 15 Pages: 102-104
• [Journal Article] E-test versus agar dilution for antibiotic susceptibility testing of Helicobacter pylori: a comparison study (2020)
  • Author(s): Miftahussurur Muhammad、Fauzia Kartika Afrida、Nusi Iswan Abbas、Setiawan Poernomo Boedi、Syam Ari Fahrial、Waskito Langgeng Agung、Doohan Dalla、Ratnasari Neneng、Khomsan Ali、Adnyana I. Ketut、Akada Junko、Yamaoka Yoshio
  • Journal Title: BMC Research Notes Volume: 13 Issue: 1 Pages: 22-22
  • DOI: 10.1186/s13104-019-4877-9
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Characterization of a novel Helicobacter pylori East Asian-type CagA ELISA for detecting patients infected with various cagA genotypes (2020)
  • Author(s): Doohan D, Miftahussurur M, Matsuo Y, Kido Y, Akada J, Matsuhisa T, Yee TT, Htet K, Aftab H, Vilaichone RK, Mahachai V, Ratanachu-Ek T, Tshering L, Waskito LA, Fauzia KA, Uchida T, Syam AF, Rezkitha YAA, Yamaoka Y
  • Journal Title: Medcal Microbiology and Immunology Volume: 209 Issue: 1 Pages: 29-40
  • DOI: 10.1007/s00430-019-00634-5
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] H.pylori遺伝子解析による人類の起源について (2020)
  • Author(s): 山岡吉生
  • Journal Title: The GI forefront Volume: 15(2) Pages: 102-104
  • Peer Reviewed
• [Journal Article] Importance of Toll-like Receptors in Pro-inflammatory and Anti-inflammatory Responses by Helicobacter pylori Infection (2019)
  • Author(s): Nagashima Hiroyuki、Yamaoka Yoshio
  • Journal Title: Curr Top Microbiol Immunol Volume: 421 Pages: 139-158
  • DOI: 10.1007/978-3-030-15138-6_6
  • ISBN: 9783030151379, 9783030151386
  • Peer Reviewed
• [Journal Article] Role of Vonoprazan in Helicobacter pylori Eradication Therapy in Japan (2019)
  • Author(s): Sugimoto Mitsushige、Yamaoka Yoshio
  • Journal Title: Frontiers in Pharmacology Volume: 9 Pages: 1560-1560
  • DOI: 10.3389/fphar.2018.01560
  • Peer Reviewed / Open Access
• [Journal Article] Gastric Microbiota in Helicobacter pylori-Negative and -Positive Gastritis Among High Incidence of Gastric Cancer Area (2019)
  • Author(s): Gantuya Boldbaatar、El-Serag Hashem B.、Matsumoto Takashi、Ajami Nadim J.、Oyuntsetseg Khasag、Azzaya Dashdorj、Uchida Tomohisa、Yamaoka Yoshio
  • Journal Title: Cancers Volume: 11 Issue: 4 Pages: 504-504
  • DOI: 10.3390/cancers11040504
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Initial Trials With Susceptibility-Based and Empiric Anti-H. pylori Therapies in Mongolia (2019)
  • Author(s): Byambajav Tsogt-Ochir、Bira Namdag、Choijamts Gotov、Davaadorj Duger、Gantuya Boldbaatar、Sarantuya Tserenchimed、Sarantuya Gidaagaya、Enkhtsetseg Altangerel、Erdenetsogt Dungubat、Battulga Adiyasuren、Tserentogtokh Tegshee、Matsuhisa Takeshi、Yamaoka Yoshio、Oyuntsetseg Khasag
  • Journal Title: Frontiers in Pharmacology Volume: 10 Pages: 394-394
  • DOI: 10.3389/fphar.2019.00394
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] CYP2C19 Genotype, CagA Genotype and Antibiotic Resistant Strain of Helicobacter pylori Infection (2019)
  • Author(s): Jeerayuth Auttajaroon, Peranart Chotivitayatarakorn, Yoshio Yamaoka, Ratha-Korn Vilaichone
  • Journal Title: Asian Pac J Cancer Prev. Volume: 20 Pages: 1243-1247
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Analysis of risks of gastric cancer by gastric mucosa among Indonesian ethnic groups (2019)
  • Author(s): Miftahussurur Muhammad、Waskito Langgeng Agung、Syam Ari Fahrial、et al.、Yamaoka Yoshio
  • Journal Title: PLOS ONE Volume: 14 Issue: 5 Pages: e0216670-e0216670
  • DOI: 10.1371/journal.pone.0216670
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Western-Type Helicobacter pylori CagA are the Most Frequent Type in Mongolian Patients (2019)
  • Author(s): Tserentogtokh Tegshee、Gantuya Boldbaatar、Subsomwong Phawinee、Oyuntsetseg Khasag、Bolor Dashdorj、Erdene-Ochir Yansan、Azzaya Dashdorj、Davaadorj Duger、Uchida Tomohisa、Matsuhisa Takeshi、Yamaoka Yoshio
  • Journal Title: Cancers Volume: 11 Issue: 5 Pages: 725-725
  • DOI: 10.3390/cancers11050725
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Changes of tight junction and interleukin‐8 expression using a human gastroid monolayer model of Helicobacter pylori infection (2019)
  • Author(s): Uotani Takahiro、Murakami Kosuke、Uchida Tomohisa、Tanaka Shingo、Nagashima Hiroyuki、Zeng Xi‐Lei、Akada Junko、Estes Mary K.、Graham David Y.、Yamaoka Yoshio
  • Journal Title: Helicobacter Volume: 24 Issue: 3
  • DOI: 10.1111/hel.12583
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] A Next-Generation Sequencing-Based Approach to Identify Genetic Determinants of Antibiotic Resistance in Cambodian Helicobacter pylori Clinical Isolates (2019)
  • Author(s): Tuan Vo Phuoc、Narith Dou、Tshibangu-Kabamba Evariste、Dung Ho Dang Quy、Viet Pham Thanh、Sokomoth Sin、Binh Tran Thanh、Sokhem Sok、Tri Tran Dinh、Ngov Seng、Tung Pham Huu、Thuan Ngo Phuong Minh、Truc Tran Cong、Phuc Bui Hoang、Matsumoto Takashi、Fauzia Kartika Afrida、Akada Junko、Trang Tran Thi Huyen、Yamaoka Yoshio
  • Journal Title: Journal of Clinical Medicine Volume: 8 Issue: 6 Pages: 858-858
  • DOI: 10.3390/jcm8060858
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Management of Antibiotic-Resistant Helicobacter pylori Infection: Perspectives from Vietnam (2019)
  • Author(s): Khien Vu Van、Thang Duong Minh、Hai Tran Manh、Duat Nguyen Quang、Khanh Pham Hong、Ha Dang Thuy、Binh Tran Thanh、Dung Ho Dang Quy、Trang Tran Thi Huyen、Yamaoka Yoshio
  • Journal Title: Gut and Liver Volume: 13 Issue: 5 Pages: 483-497
  • DOI: 10.5009/gnl18137
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Genome-wide mutation analysis of Helicobacter pylori after inoculation to Mongolian gerbils (2019)
  • Author(s): Suzuki Rumiko、Satou Kazuhito、Shiroma Akino、Shimoji Makiko、Teruya Kuniko、Matsumoto Takashi、Akada Junko、Hirano Takashi、Yamaoka Yoshio
  • Journal Title: Gut Pathogens Volume: 11 Issue: 1 Pages: 1-6
  • DOI: 10.1186/s13099-019-0326-5
  • Peer Reviewed / Open Access
• [Journal Article] Comparative study between Helicobacter pylori and host human genetics in the Dominican Republic (2019)
  • Author(s): Ono Takaaki、Cruz Modesto、Jimenez Abreu Jose A.、Nagashima Hiroyuki、Subsomwong Phawinee、Hosking Celso、Shiota Seiji、Suzuki Rumiko、Yamaoka Yoshio
  • Journal Title: BMC Evolutionary Biology Volume: 19 Issue: 1 Pages: 197-197
  • DOI: 10.1186/s12862-019-1526-9
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Helicobacter pylori Virulence Factors Exploiting Gastric Colonization and its Pathogenicity (2019)
  • Author(s): Ansari Shamshul、Yamaoka Yoshio
  • Journal Title: Toxins Volume: 11 Issue: 11 Pages: 677-677
  • DOI: 10.3390/toxins11110677
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Epitope peptides of Helicobacter pylori CagA antibodies from sera by whole-peptide mapping (2019)
  • Author(s): Shamshul Ansari ; Junko Akada; Yuichi Matsuo; Seiji Shiota; Yoko Kudo; Tadayoshi Okimoto; Kazunari Murakami; Yoshio Yamaoka
  • Journal Title: J Gastroenterology Volume: 54 Issue: 12 Pages: 1039-1051
  • DOI: 10.1007/s00535-019-01584-8
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] 海外Helicobacter pylori疫学調査―立案,調査からデータ解析に至るまで―第19回 アフリカでの疫学調査―その1 (2019)
  • Author(s): 山岡吉生
  • Journal Title: Helicobacter Research Volume: 23 Pages: 5-11
  • NAID: 40021896182
  • Peer Reviewed
• [Journal Article] 海外Helicobacter pylori疫学調査―立案,調査からデータ解析に至るまで―第19回 アフリカでの疫学調査―その2;コンゴ民主共和国 (2019)
  • Author(s): 山岡吉生
  • Journal Title: Helicobacter Research Volume: 23 Pages: 169-177
  • Peer Reviewed
• [Journal Article] H. pyloriが疾患を起こす機序および H. pyloriを用いた人類学的研究 (2019)
  • Author(s): 山岡吉生
  • Journal Title: 日本ヘリコバクター学会誌 Volume: 21(1) Pages: 13-20
  • Peer Reviewed
• [Journal Article] Helicobacter pyloriの毒素VacAは多くの細胞に様々な影響を及ぼす (2019)
  • Author(s): 永島裕之、山岡吉生
  • Journal Title: Helicobacter日本語抄訳版 Volume: 19 Pages: 4-8
  • Peer Reviewed
• [Journal Article] <p>Alternative eradication regimens for <em>Helicobacter pylori</em> infection in Indonesian regions with high metronidazole and levofloxacin resistance</p> (2019)
  • Author(s): Miftahussurur Muhammad、Waskito Langgeng Agung、Syam Ari Fahrial、Nusi Iswan Abbas、Siregar Gontar、Richardo Marselino、Bakry Achmad Fuad、Rezkitha Yudith Annisa Ayu、Wibawa I Dewa Nyoman、Yamaoka Yoshio
  • Journal Title: Infection and Drug Resistance Volume: Volume 12 Pages: 345-358
  • DOI: 10.2147/idr.s187063
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Effective therapeutic regimens in two South Asian countries with high resistance to major Helicobacter pylori antibiotics (2019)
  • Author(s): Miftahussurur Muhammad、Aftab Hafeza、Shrestha Pradeep Krishna、Sharma Rabi Prakash、Subsomwong Phawinee、Waskito Langgeng Agung、Doohan Dalla、Fauzia Kartika Afrida、Yamaoka Yoshio
  • Journal Title: Antimicrobial Resistance & Infection Control Volume: 8 Issue: 1 Pages: 40-40
  • DOI: 10.1186/s13756-019-0482-x
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Five alternative Helicobacter pylori antibiotics to counter high levofloxacin and metronidazole resistance in the Dominican Republic (2019)
  • Author(s): Miftahussurur Muhammad、Cruz Modesto、Doohan Dalla、Subsomwong Phawinee、Abreu Jos? A. Jim?nez、Hosking Celso、Waskito Langgeng Agung、Yamaoka Yoshio
  • Journal Title: PLOS ONE Volume: 14 Issue: 3 Pages: e0213868-e0213868
  • DOI: 10.1371/journal.pone.0213868
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Aggregatibacter actinomycetemcomitans infection causes DNA double-strand breaks in host cells (2018)
  • Author(s): Teshima Rie、Hanada Katsuhiro、Akada Junko、Kawano Kenji、Yamaoka Yoshio
  • Journal Title: Genes to Cells Volume: 23 Issue: 4 Pages: 264-273
  • DOI: 10.1111/gtc.12570
  • Peer Reviewed / Open Access
• [Journal Article] The prevalence of Helicobacter pylori infection and other risk factors among Mongolian dyspeptic patients who have a high incidence and mortality rate of gastric cancer (2018)
  • Author(s): Khasag Oyuntsetseg、Boldbaatar Gantuya、Tegshee Tserentogtoh、Duger Davaadorj、Dashdorj Azzaya、Uchida Tomohisa、Matsuhisa Takeshi、Yamaoka Yoshio
  • Journal Title: Gut Pathogens Volume: 10 Issue: 1 Pages: 14-14
  • DOI: 10.1186/s13099-018-0240-2
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Distribution and clinical associations of integrating conjugative elements and cag pathogenicity islands of Helicobacter pylori in Indonesia (2018)
  • Author(s): Waskito Langgeng Agung、Miftahussurur Muhammad、Lusida Maria Inge、Syam Ari Fahrial、Suzuki Rumiko、Subsomwong Phawinee、Uchida Tomohisa、Hamdan Muhammad、Nasronudin、Yamaoka Yoshio
  • Journal Title: Scientific Reports Volume: 8 Issue: 1 Pages: 6073-6073
  • DOI: 10.1038/s41598-018-24406-y
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Epidemiology of Helicobacter pylori and CagA-Positive Infections and Global Variations in Gastric Cancer (2018)
  • Author(s): Park Jin、Forman David、Waskito Langgeng、Yamaoka Yoshio、Crabtree Jean
  • Journal Title: Toxins Volume: 10 Issue: 4 Pages: 163-163
  • DOI: 10.3390/toxins10040163
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Prevalence and Pattern of Antibiotic Resistant Strains of Helicobacter Pylori Infection in ASEAN (2018)
  • Author(s): Vilaichone RK, Quach DT, Yamaoka Y, Sugano K, Mahachai V
  • Journal Title: Asian Pacific Journal of Cancer Prevention Volume: 19 Pages: 1411-1413
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Prevalence of Helicobacter pylori and its CagA subtypes in gastric cancer and duodenal ulcer at an Austrian tertiary referral center over 25 years (2018)
  • Author(s): Kamogawa-Schifter Yumiko、Yamaoka Yoshio、Uchida Tomohisa、Beer Andrea、Tribl Barbara、Scheiger-Hekele Maximilian、Trauner Michael、Dolak Werner
  • Journal Title: PLOS ONE Volume: 13 Issue: 5 Pages: e0197695-e0197695
  • DOI: 10.1371/journal.pone.0197695
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Genetic diversity and functional analysis of oipA gene in association with other virulence factors among Helicobacter pylori isolates from Iranian patients with different gastric diseases (2018)
  • Author(s): Farzi Nastaran、Yadegar Abbas、Aghdaei Hamid Asadzadeh、Yamaoka Yoshio、Zali Mohammad Reza
  • Journal Title: Infection, Genetics and Evolution Volume: 60 Pages: 26-34
  • DOI: 10.1016/j.meegid.2018.02.017
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Genetic populations and virulence factors of Helicobacter pylori (2018)
  • Author(s): Kabamba Evariste Tshibangu、Tuan Vo Phuoc、Yamaoka Yoshio
  • Journal Title: Infection, Genetics and Evolution Volume: 60 Pages: 109-116
  • DOI: 10.1016/j.meegid.2018.02.022
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Call for shift in Helicobacter pylori treatment (2018)
  • Author(s): Talebi Bezmin Abadi Amin、Yamaoka Yoshio
  • Journal Title: European Journal of Gastroenterology & Hepatology Volume: 30 Issue: 6 Pages: 687-687
  • DOI: 10.1097/meg.0000000000001096
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Current understanding and management of Helicobacter pylori infection: an updated appraisal (2018)
  • Author(s): Ansari Shamshul、Yamaoka Yoshio
  • Journal Title: F1000Research Volume: 7 Pages: 721-721
  • DOI: 10.12688/f1000research.14149.1
  • Peer Reviewed / Open Access
• [Journal Article] How to eliminate gastric cancer-related death worldwide? (2018)
  • Author(s): Yamaoka Yoshio
  • Journal Title: Nature Reviews Clinical Oncology Volume: 15 Issue: 7 Pages: 407-408
  • DOI: 10.1038/s41571-018-0029-8
  • Peer Reviewed
• [Journal Article] Therapeutic effect of lyophilized, Kefir-fermented milk on constipation among persons with mental and physical disabilities (2018)
  • Author(s): Maki Rumiko、Matsukawa Mayumi、Matsuduka Atsuko、Hashinaga Masahiko、Anai Hirofumi、Yamaoka Yoshio、Hanada Katsuhiro、Fujii Chieko
  • Journal Title: Japan Journal of Nursing Science Volume: 15 Issue: 3 Pages: 218-225
  • DOI: 10.1111/jjns.12189
  • Peer Reviewed
• [Journal Article] Anti-proliferation effect of blue light-emitting diodes against antibiotic-resistant Helicobacter pylori (2018)
  • Author(s): Ma Jianwei、Hiratsuka Takahiro、Etoh Tsuyoshi、Akada Junko、Fujishima Hajime、Shiraishi Norio、Yamaoka Yoshio、Inomata Masafumi
  • Journal Title: Journal of Gastroenterology and Hepatology Volume: なし Issue: 8 Pages: 1492-1499
  • DOI: 10.1111/jgh.14066
  • Peer Reviewed / Open Access
• [Journal Article] New observations regarding Helicobacter pylori and gastric cancer in Mongolia (2018)
  • Author(s): Gantuya Boldbaatar、Bolor Dashdorj、Oyuntsetseg Khasag、Erdene-Ochir Yansan、Sanduijav Ruvjir、Davaadorj Duger、Tserentogtokh Tegshee、Azzaya Dashdorj、Uchida Tomohisa、Matsuhisa Takeshi、Yamaoka Yoshio
  • Journal Title: Helicobacter Volume: 23 Issue: 4
  • DOI: 10.1111/hel.12491
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Diffuse Gastric Cancer: A Summary of Analogous Contributing Factors for Its Molecular Pathogenicity (2018)
  • Author(s): Ansari Shamshul、Gantuya Boldbaatar、Tuan Vo、Yamaoka Yoshio
  • Journal Title: International Journal of Molecular Sciences Volume: 19 Issue: 8 Pages: 2424-2424
  • DOI: 10.3390/ijms19082424
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Helicobacter pylori therapy and clinical perspective (2018)
  • Author(s): Talebi Bezmin Abadi A, Yamaoka Y
  • Journal Title: J Glob Antimicrob Resist Volume: S2213 Pages: 30057-2
  • DOI: 10.1016/j.jgar.2018.03.005
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Pathogenesis of Helicobacter pylori infection (2018)
  • Author(s): Waskito Langgeng Agung、Salama Nina R.、Yamaoka Yoshio
  • Journal Title: Helicobacter Volume: 23 Issue: Suppl 1
  • DOI: 10.1111/hel.12516
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Gastroesophageal reflux disease in an area with low Helicobacter pylori infection prevalence (2018)
  • Author(s): Miftahussurur Muhammad、Doohan Dalla、Nusi Iswan Abbas、Adi Pangestu、Rezkitha Yudith Annisa Ayu、Waskito Langgeng Agung、Fauzia Kartika Afrida、Bramantoro Taufan、Maimunah Ummi、Thamrin Husin、Masithah Safitri Indah、Sukadiono Sukadiono、Uchida Tomohisa、Lusida Maria Inge、Yamaoka Yoshio
  • Journal Title: PLOS ONE Volume: 13 Issue: 11 Pages: e0205644-e0205644
  • DOI: 10.1371/journal.pone.0205644
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] The role of integrating conjugative elements in Helicobacter pylori: a review (2018)
  • Author(s): Waskito Langgeng Agung、Yih-Wu Jeng、Yamaoka Yoshio
  • Journal Title: Journal of Biomedical Science Volume: 25 Issue: 1 Pages: 86-86
  • DOI: 10.1186/s12929-018-0489-2
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Helicobacter pylori Infection and Related Gastrointestinal Diseases in Southeast Asian Countries: An Expert Opinion Survey (2018)
  • Author(s): Quach Duc Trong、Vilaichone Ratha-korn、Vu Khien Van、Yamaoka Yoshio、Sugano Kentaro、Mahachai Varocha
  • Journal Title: Asian Pacific Journal of Cancer Prevention Volume: 19 Issue: 12 Pages: 3565-3569
  • DOI: 10.31557/apjcp.2018.19.12.3565
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Evaluation of serum markers for gastric cancer and its precursor diseases among high incidence and mortality rate of gastric cancer area (2018)
  • Author(s): Gantuya Boldbaatar、Oyuntsetseg Khasag、Bolor Dashdorj、Erdene-Ochir Yansan、Sanduijav Ruvjir、Davaadorj Duger、Tserentogtokh Tegshee、Uchida Tomohisa、Yamaoka Yoshio
  • Journal Title: Gastric Cancer Volume: 22 Issue: 1 Pages: 104-112
  • DOI: 10.1007/s10120-018-0844-8
  • NAID: 40021775217
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Dysbiosis of the Gut Microbiota on the Inflammatory Background due to Lack of Suppressor of Cytokine Signalling-1 in Mice (2018)
  • Author(s): Gendo Y、Matsumoto T、Kamiyama N、Saechue B、Fukuda C、Dewayani A、Hidano S、Noguchi K、Sonoda A、Ozaki T、Sachi N、Hirose H、Ozaka S、Eshita Y、Mizukami K、Okimoto T、Kodama M、Yoshimatsu T、Nishida H、Daa T、Yamaoka Y、Murakami K、Kobayashi T
  • Journal Title: Inflammatory Intestinal Diseases Volume: 3 Issue: 3 Pages: 145-154
  • DOI: 10.1159/000495462
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Presentation] Outer membrane protein HopF is involved in biofilm formation and virulence in Helicobacter pylori (2023)
  • Author(s): Fauzia KA, Sugawara Y, Obata, M, Amalia R, Alfaray RI, Metadea C, Akada, J, Matsumoto, T, Miftahussurur M, Yamaoka Y.
  • Organizer: The 19th Korea-Japan H. pylori Joint Symposium, Gut and liver
  • Int'l Joint Research
• [Presentation] Microbiome analysis for the diagnosis of H. pylori infection (2023)
  • Author(s): Yoshio Yamaoka
  • Organizer: International Symposium on Helicobacter and Upper Gastrointestinal Disease
  • Int'l Joint Research / Invited
• [Presentation] Gastric microbiota and H. pylori in an Asian population (2023)
  • Author(s): Yoshio Yamaoka
  • Organizer: International Symposium on Helicobacter and Upper Gastrointestinal Disease
  • Int'l Joint Research / Invited
• [Presentation] Mutations Related to Antibiotics Resistance in Helicobacter pylori Clinical Isolates from Bangladesh (2023)
  • Author(s): Fauzia, KA, Hafeza A, Tshibangu-Kabamba E, Alfaray RI, Batsaikhan S, Cimuanga-Mukanya A, Matsumoto T, Subsomwong P, Akada J, Miftahussurur M, Yamaoka Y.
  • Organizer: International Symposium on Helicobacter and Upper Gastrointestinal Disease
  • Int'l Joint Research
• [Presentation] Amoxicillin resistance in Helicobacter pylori: Identification of new resistance-conferring mutations in the penicillin-binding protein 1A (2023)
  • Author(s): Cimuanga-Mukanya A, Tshibangu-Kabamba E, Ngoma-Kisoko PdeJ , Disashi-Tumba G, Matsumoto T,Akada J and Yamaoka Y
  • Organizer: The 19th Korea-Japan H. pylori Joint Symposium
  • Int'l Joint Research
• [Presentation] Utilization of an Automated Latex Agglutination Turbidity Assay for Assessing Gastric Mucosal Alteration during Helicobacter pylori Infection (2023)
  • Author(s): Khangai A Akada J, Azzaya D, Batsaikhan S, Gantuya B, Oyuntsetseg K, Davaadaorj D, Matsumoto T, Uchida T, Akada J, and Yamaoka Y.
  • Organizer: The 19th Korea-Japan H. pylori Joint Symposium, Gut and liver
  • Int'l Joint Research
• [Presentation] Entroccus Hirae Attenuates chemokine and Induces Dna Damage In Gastric Epithelial Cell (2023)
  • Author(s): Saruuljavkhlan B, Yamaoka Y
  • Organizer: DDW2023
  • Int'l Joint Research
• [Presentation] Investigation of Low－Grade Intestinal Metaplasia From Clinical Dyspepsia Patients INA Country With Low-Incidence of Gastric Cancer:From Human to Helicobactor pylori Perspective (2023)
  • Author(s): Ricky indra alfary, Yamaoka Y
  • Organizer: DDW2023
  • Int'l Joint Research
• [Presentation] Human gut microbiota related to GI tract diseases (2023)
  • Author(s): Yoshio Yamaoka
  • Organizer: ASEAN GASTRO2023
  • Int'l Joint Research / Invited
• [Presentation] H.pylori evolujtion and pathogenesis in Asia (2023)
  • Author(s): Yoshio Yamaoka
  • Organizer: HGSC2023
  • Int'l Joint Research / Invited
• [Presentation] Helicobacter pylori eradication experiences in Bhutan (2023)
  • Author(s): Yoshio Yamaoka
  • Organizer: APDW2023
  • Int'l Joint Research / Invited
• [Presentation] comprehensive genomic analysis of helicobacter pylori in highand low gastric cancer risk populations (2023)
  • Author(s): Saruuljavkhlan B, Yamaoka Y
  • Organizer: APDW2023
  • Int'l Joint Research
• [Presentation] Helicobacter pylori eradication experiences in Bhutan (2023)
  • Author(s): Ricky indra alfary, Yamaoka Y
  • Organizer: APDW2023
  • Int'l Joint Research
• [Presentation] Outer membrane protein HopF is involved in biofilm formation and virulence in Helicobacter pylori. (2023)
  • Author(s): Kartika Afrida Fauzia, Yuri Sugawara, Mayu Obata, Rizki Amalia, Ricky Indra Alfaray, Camilia Metadea, Junko Akada, Takashi Matsumoto, Muhammad Miftahussurur, Yoshio Yamaoka.
  • Organizer: The 19th Korea-Japan H. pylori Joint Symposium
  • Int'l Joint Research
• [Presentation] Microbiome analysis for the diagnosis of H. pylori infection. (2023)
  • Author(s): Yamaoka Y.
  • Organizer: International Symposium on Helicobacter and Upper Gastrointestinal Disease
  • Int'l Joint Research / Invited
• [Presentation] Gastric microbiota and H. pylori in an Asian population. (2023)
  • Author(s): Yamaoka Y.
  • Organizer: International Symposium on Helicobacter and Upper Gastrointestinal Disease
  • Int'l Joint Research / Invited
• [Presentation] Mutations Related to Antibiotics Resistance in Helicobacter pylori Clinical Isolates from Bangladesh. (2023)
  • Author(s): Fauzia, Kartika Afrida, Hafeza Aftab, Evariste Tshibangu-Kabamba, Ricky Indra Alfaray, Batsaikhan Saruuljavkhlan, Alain Cimuanga-Mukanya, Takashi Matsumoto, Phawinee Subsomwong, Junko Akada, Muhammad Miftahussurur, and Yoshio Yamaoka.
  • Organizer: International Symposium on Helicobacter and Upper Gastrointestinal Disease
  • Int'l Joint Research
• [Presentation] Amoxicillin resistance in Helicobacter pylori: Identification of new resistance-conferring mutations in the penicillin-binding protein 1A. (2023)
  • Author(s): Cimuanga-Mukanya A, Tshibangu-Kabamba E, Ngoma-Kisoko PdeJ , Disashi-Tumba G, Matsumoto T,Akada J and Yamaoka Y.
  • Organizer: The 19th Korea-Japan H. pylori Joint Symposium
  • Int'l Joint Research
• [Presentation] Utilization of an Automated Latex Agglutination Turbidity Assay for Assessing Gastric Mucosal Alteration during Helicobacter pylori Infection. (2023)
  • Author(s): Khangai A Akada J, Azzaya D, Batsaikhan S, Gantuya B, Oyuntsetseg K, Davaadaorj D, Matsumoto T, Uchida T, Akada J, and Yamaoka Y.
  • Organizer: The 19th Korea-Japan H. pylori Joint Symposium
  • Int'l Joint Research
• [Presentation] Ancient human footprints left in Helicobacter pylori. (2022)
  • Author(s): Yamaoka Y.
  • Organizer: The 11th Asian Pacific Topic Conference in the 108th General Meeting of the Japanese Society of Gastroenterology
  • Int'l Joint Research / Invited
• [Presentation] Biofilm Formation and antibiotic resistance phenotype of Helicobacter pylori clinical isolates. (2022)
  • Author(s): Fauzia KA, Matsumoto T, Akada J, Yonezawa H, Kamiya S, Yamaoka Y.
  • Organizer: The 18th Japan-Korea H. pylori Joint Symposium,
  • Int'l Joint Research
• [Presentation] The impact of mobile genetic elemants and toxin-antitoxin system on Helicobacter pylori adaptability and antimicrobial resistance: A wisdom from Japan-South Korea whole-genome sequence collection. (2022)
  • Author(s): Alfaray RI, Batsaikhan S, Fauzia KA, Akada J, Matsumoto T, Yamaoka Y.
  • Organizer: The 18th Japan-Korea H. pylori Joint Symposium,
  • Int'l Joint Research
• [Presentation] Identification of the Helicobacter pylori genomic islands in a high gastric cancer region. (2022)
  • Author(s): Batsaikhan S, Alfaray RI, Matsumoto T, Akada J, Yamaoka Y.
  • Organizer: The 18th Japan-Korea H. pylori Joint Symposium,
  • Int'l Joint Research
• [Presentation] Helicobacter pylori and host human genetics in the Caribbean countries. (2022)
  • Author(s): Yamaoka Y.
  • Organizer: IX INTERNATIONAL SYMPOSIUM OF Helicobacter pylori INFECTION AND GASTRIC CANCER
  • Int'l Joint Research / Invited
• [Presentation] Helicobacter pylori isolates from Mongolia describing gastric carcinogenesis and human migration. (2022)
  • Author(s): Gantuya B, Yoshio Y, Oyuntsetseg K.
  • Organizer: 2022 The Japanese Society of Medical Oncology Annual Meeting
  • Int'l Joint Research
• [Presentation] Global genome study of helicobacter pylori phage opens new paradigm on their worldwide distribution, genetic feature, and impacts on antimicrobial resistance, disease advancement, and achievement for phage-based therapy. (2022)
  • Author(s): Alfaray IR, Saruuljavkhlan B, Fauzia KA, Matsumoto T, Yamaoka Y.
  • Organizer: Gut
  • Int'l Joint Research
• [Presentation] A novel pathogen enterococcus hirae induced dysbiosis in the stomach and the genomic instability to promote gastric cancer. (2022)
  • Author(s): Saruuljavkhlan B, Gantuya B, Akada J, Matsumoto T, Alfaray RI, Oyuntsetseg K, Yamaoka Y.
  • Organizer: Gut
  • Int'l Joint Research
• [Presentation] Pro-Inflammatory Cytokine Expression Observed During Helicobacter pylori Infection Revealed the Possibility Reason of Low-Grade Intestinal Metaplasia in Indonesia. (2022)
  • Author(s): Rezkitha, Y.A, Yamaoka Y.
  • Organizer: ASEAN Stomach and Microbiota Study Group
  • Int'l Joint Research
• [Presentation] Worldwide Helicobacter pylori Phage Study: Genome Analysis, Epidemiology, Clinical Data, until New Phage-based Medicine Candidate. (2022)
  • Author(s): Alfaray RI, Yamaoka Y.
  • Organizer: The 21st International Workshop on Campylobacter, Helicobacter and Related Organisms
  • Int'l Joint Research
• [Presentation] Comprehensive Study of Helicobacter pylori Genomic Islands and Their Correlation to Gastric Diseases, Phylogenetic Pattern. (2022)
  • Author(s): Saruuljavkhlan B, Yamaoka Y.
  • Organizer: The 21st International Workshop on Campylobacter, Helicobacter and Related Organisms
  • Int'l Joint Research
• [Presentation] Identification of Flagella and Outer Membrane Protein Genes associated with Biofilm Formation. (2022)
  • Author(s): Kartika Afrida Fauzia, Yamaoka Y.
  • Organizer: The 21st International Workshop on Campylobacter, Helicobacter and Related Organisms
  • Int'l Joint Research
• [Presentation] Effect of gastric microbiota to gastric cancer development. (2022)
  • Author(s): Yamaoka Y.
  • Organizer: 28th Conference on Gastroenterology & Hepatology by VIETNAM ASSOCIATION OF GASTROENTEROLOGY
  • Int'l Joint Research / Invited
• [Presentation] H. pylori and the pathogenesis of gastric cancer. (2022)
  • Author(s): Yamaoka Y.
  • Organizer: ASEAN Gastro2022
  • Int'l Joint Research / Invited
• [Presentation] Molecular epidemiological studies of Helicobacter pylori infection (2021)
  • Author(s): Yoshio Yamaoka
  • Organizer: Mongolian Digestive Disease Week 2021
  • Int'l Joint Research / Invited
• [Presentation] Epidemiology and Clinical Relevance of Helicobacter pylori and Gastric Microbiome in Asia (2021)
  • Author(s): Yoshio Yamaoka
  • Organizer: Univeristas Airlangga and Oita University 1st Joint symposium & workshop in Medicine
  • Int'l Joint Research / Invited
• [Presentation] Impact of Helicobacter pylori eradication on human health (2021)
  • Author(s): Yoshio Yamaoka
  • Organizer: Asian Pacific Digestive Week 2021 (APDW2021)
  • Int'l Joint Research / Invited
• [Presentation] Helicobacter's type 4 secretion systems as a gastroduodenal diseases marker (2021)
  • Author(s): Bui Hoang Phuc, Vo Phuoc Tuan, Ho Dang Quy Dung, Tran Thanh Binh, Pham Huu Tung, Tran Dinh Tri, Ngo Phuong Minh Thuan, Vu Van Khien, Tran Thi Huyen Trang, Junko Akada, Takeshi Matsumoto, and Yoshio Yamaoka
  • Organizer: European Helicobacter and Microbiome Study Group annual meeting
  • Int'l Joint Research
• [Presentation] Potential role of single nucleotide polymorphism of gluP and cgt genes in H. pylori biofilm formation (2021)
  • Author(s): Afrida Fauzia, Hafeza Aftab, Muhammad Miftahussurur, Langgeng Agung Waskito, Vo Phuoc Tuan , Takashi Matsumoto, Michiyuki Yurugi, Evariste Tshibangu Kabamba, Junko Akada, Yoshio Yamaoka
  • Organizer: European Helicobacter and Microbiome Study Group annual meeting
  • Int'l Joint Research
• [Presentation] 胃癌特異的一塩基多型を有するピロリ菌dsbG遺伝子の比較機能解析 (2021)
  • Author(s): 赤田純子、松本昂、沖本忠義、村上和成、山岡吉生
  • Organizer: 第27回日本ヘリコバクター学会学術集会
• [Presentation] ピロリ菌はsmall RNAによって宿主適応を制御する (2021)
  • Author(s): 三室仁美, 木下遼, 山岡吉生
  • Organizer: 第27回日本ヘリコバクター学会学術集会
• [Presentation] Helicobacter pylori infection and gastric microbiota (2021)
  • Author(s): Yoshio Yamaoka
  • Organizer: International conference “Translational and Clinical Research Development in Mongolia” for the 60th anniversary of the Institute of Medical Sciences
  • Int'l Joint Research / Invited
• [Presentation] H. pylori and clinical correlation (gastric and extra-gastric diseases) (2021)
  • Author(s): Yoshio Yamaoka
  • Organizer: ASEAN Stomach and Microbiota Study Group Meeting
  • Int'l Joint Research / Invited
• [Presentation] Atrophic gastritis and other chronic inflammation and gastric carcinogenesis (2021)
  • Author(s): Yoshio Yamaoka
  • Organizer: 5th Korea Digestive Disease Week (KDDW 2021)
  • Int'l Joint Research / Invited
• [Presentation] Helicobacter pylori: pathogenesis and correlation with intra and extra gastric disease. (2021)
  • Author(s): Yoshio Yamaoka
  • Organizer: Basic Research for Young Scientist (BAYONET)
  • Invited
• [Presentation] 胃癌特異的一塩基多型を有するピロリ菌遺伝子の比較機能解析 (2021)
  • Author(s): 山岡吉生
  • Organizer: 2021九州微生物研究会
  • Invited
• [Presentation] Importance of Helicobacter pylori eradication on human health (2021)
  • Author(s): Yoshio Yamaoka
  • Organizer: 7th China-Japan GI exchange forum
  • Int'l Joint Research / Invited
• [Presentation] The virulence factor of H. pylori in gastric cancer (2021)
  • Author(s): Yoshio Yamaoka
  • Organizer: 27th Scientific Conference of Vietnam Association of Gastroenterology
  • Int'l Joint Research / Invited
• [Presentation] H. pylori Infection Surveillance Across Asia (2021)
  • Author(s): Yoshio Yamaoka
  • Organizer: International Workshop Series of Gastroenterology Research Opportunities in Antimicrobial Resistance, Metagenomic, Clinical Surveillance and Web-Lab Experiment
  • Int'l Joint Research / Invited
• [Presentation] Biofilm Formation: What and How to Examine? (2021)
  • Author(s): Kartika Afrida Fauzia, Yoshio Yamaoka
  • Organizer: International Workshop Series of Gastroenterology Research Opportunities in Antimicrobial Resistance, Metagenomic, Clinical Surveillance and Web-Lab Experiment
  • Int'l Joint Research / Invited
• [Presentation] Development of a Helicobacter pylori East Asian-type CagA Immunochromatography Assay for Rapid Detection of Antibody in Serum (2021)
  • Author(s): Kartika Afrida Fauzia, Yoshio Yamaoka
  • Organizer: Korea-Japan Helicobacter research symposium
  • Int'l Joint Research / Invited
• [Presentation] Molecular epidemiological studies of Helicobacter pylori infection (2021)
  • Author(s): Yoshio Yamaoka
  • Organizer: Current Advances in gastroenterology and Hepatology 2021 Mongolia
  • Int'l Joint Research / Invited
• [Presentation] The Japan-Africa Collaborative Research on Helicobacter pylori project (2020)
  • Author(s): Yoshio Yamaoka
  • Organizer: KEMRI Annual Scientific and Health Conference
  • Int'l Joint Research / Invited
• [Presentation] Mechanistic insights of metronidazole resistance revealed by Next-Generation Sequencing of whole genome of Helicobacter pylori clinical isolates from the Democratic Republic of Congo (2020)
  • Author(s): Evariste Tshibangu Kabamba., Takashi Matsumoto, Yoshio Yamaoka
  • Organizer: KEMRI Annual Scientific and Health Conference
  • Int'l Joint Research / Invited
• [Presentation] Molecular epidemiological studies of Helicobacter pylori infection (2020)
  • Author(s): Yoshio Yamaoka
  • Organizer: Mongolian Digestive Disease Week 2020
  • Int'l Joint Research / Invited
• [Presentation] Gastric microbiota and gastroduodenal disease (2020)
  • Author(s): Yoshio Yamaoka
  • Organizer: Continuing Medical Education XXXV Internal Medicine 2020
  • Int'l Joint Research / Invited
• [Presentation] Helicobacter pylori infection and gastric microbiota (2020)
  • Author(s): Yoshio Yamaoka
  • Organizer: The 6th International Symposium on probiotics and prebiotics
  • Int'l Joint Research / Invited
• [Presentation] The Japan-;Africa Collaborative Research on Helicobacter pylori Project (2020)
  • Author(s): Yoshio Yamaoka
  • Organizer: 10th Kenya Medical Research Iinstitute Annual Scientific and Health Conference
  • Int'l Joint Research / Invited
• [Presentation] ヘリコバクター・ピロリ; 病原性と人類との共移動 (2019)
  • Author(s): 山岡吉生
  • Organizer: 第９２回日本細菌学会総会
  • Invited
• [Presentation] Performance of a novel Helicobacter pylori East Asian-type CagA ELISA for detecting patients infected with various cagA genotypes (2019)
  • Author(s): Doohan D, Miftahussurur M, Matsuo Y, Kido Y, Akada J, Waskito LA, Fauzia KA, Uchida T, Matsumoto T, Yamaoka Y
  • Organizer: 第72回日本細菌学会九州支部総会・第56回日本ウイルス学会九州支部総会
• [Presentation] ピロリ菌病原因子CagA血清抗体の主要抗原エピトープから考える免疫の作用点 (2019)
  • Author(s): 赤田順子, サムスルアンサリ, 塩田星児, 沖本忠義, 村上和成, 山岡吉生
  • Organizer: 第10回癌・炎症と抗酸化研究会
• [Presentation] 次世代の若手研究者をどう育てるか？～海外研究者育成の立場から～ (2019)
  • Author(s): 山岡吉生
  • Organizer: 第10回癌・炎症と抗酸化研究会
  • Invited
• [Presentation] ゲノムワイド関連解析を用いたピロリ菌病原因子の検索 (2019)
  • Author(s): 松本昂, 山岡吉生
  • Organizer: 第51回九州微生物学研究会
  • Invited
• [Presentation] The Japan-Africa collaborative research on Helicobacter pylori project (2019)
  • Author(s): Yoshio Yamaoka
  • Organizer: 4th South Africa-Japan University Forum Conference
  • Int'l Joint Research / Invited
• [Presentation] Current knowledge of genomics for H. pylori from Far East (2019)
  • Author(s): Yoshio Yamaoka
  • Organizer: XXXII nd International Workshop on Helicobacter & Microbiota in Inflammation & Cancer
  • Int'l Joint Research / Invited
• [Presentation] Mechanistic insights of metronidazole resistance revealed by next-generation sequencing of Helicobacter pylori from Democratic Republic of Congo (2019)
  • Author(s): Tshibangu Evariste, Tuan VP, Patrick Ngoma, Pascal Tshiamala, Antoine Tshimpi, Matsumoto T, Akada J, Kido Y, Ahuka-Mundeke Steve, Mumba-Ngoyi Dieudonne, Dishashi Tumba, Yamaoka Y
  • Organizer: The 10th International Congress on Infectious Diseases
  • Int'l Joint Research
• [Presentation] Evaluationg genomic susceptibility for gastric cancer (2019)
  • Author(s): Yoshio Yamaoka
  • Organizer: Asian Pacific Digestive Week
  • Int'l Joint Research / Invited
• [Presentation] Helicobacter pylori virulence and gastric cancer pathogenesis: current knoeledge (2019)
  • Author(s): Yoshio Yamaoka
  • Organizer: The 27th Annual Meeting of the Korean College of Helicobacter and Upper Gastrointestinal Research and the 16th Japan-Korea Joint Symposium on Helicobacter Research
  • Int'l Joint Research / Invited
• [Presentation] A potential biomarker panel to distinguish gastric cancer from duodenal ulcer: results from GWAS in East Asian-type Helicobacter pylori (2019)
  • Author(s): Vo Phuoc Tuan, Kouji Yahara, Yoshio Yamaoka
  • Organizer: The 27th Annual Meeting of the Korean College of Helicobacter and Upper Gastrointestinal Research and the 16th Japan-Korea Joint Symposium on Helicobacter Research
  • Int'l Joint Research / Invited
• [Presentation] Gastritis: Past, current and future treatment (2019)
  • Author(s): Yoshio Yamaoka
  • Organizer: World Class Professor Program in Indonesia
  • Int'l Joint Research / Invited
• [Presentation] H. pylori-related pathogenesis of diffuse-type gastric cancer (2018)
  • Author(s): Yoshio Yamaoka
  • Organizer: The 2nd Seoul international Symposium on Helicobacter
  • Int'l Joint Research / Invited
• [Presentation] Helicobacter pylori eradication and Gastric cancer prevention (2018)
  • Author(s): Yoshio Yamaoka
  • Organizer: The 2018 International Forum of Helicobacter pylori, Gastrointestinal Microbiota and the Associated diseases
  • Int'l Joint Research / Invited
• [Presentation] Updated information about the pathogenesis of Helicobacter pylori infection (2018)
  • Author(s): Yoshio Yamaoka
  • Organizer: The 8th Shanghai International Conference of Gastroenterology
  • Int'l Joint Research / Invited
• [Presentation] Non-Helicobacter pylori microbiome in gastric carcinogenesis (2018)
  • Author(s): Yoshio Yamaoka
  • Organizer: Asian Pacific Digestive Week（APDW 2018)
  • Int'l Joint Research / Invited
• [Presentation] Helicobacter pylori: Challenging the present and future (2018)
  • Author(s): Yoshio Yamaoka
  • Organizer: Makassar Gastroenterology Hepatology Update 2018 (MAGEHAP2018) & Gastroenterology-Hepatology Update; Surabaya-Denpasar- Malang-Makassar 14 (SUDEMMA14) Joint conference
  • Int'l Joint Research / Invited
• [Presentation] 胃のマイクロバイオームに関する検討 (2018)
  • Author(s): 山岡吉生
  • Organizer: 平成30年度（第50回）九州微生物研究会総会
  • Invited
• [Book] ピロリ除菌治療パーフェクトガイド【電子版付】 (2020)
  • Author(s): 山岡 吉生、榊 信廣（編集）
  • Total Pages: 244
  • Publisher: 日本医事新報社
  • ISBN: 9784784944972
• [Book] 胃がんリスク層別化検診（ABC検診） (2019)
  • Author(s): 三木 一正（編集） 山岡 吉生（分担）
  • Total Pages: 234
  • Publisher: 南山堂
  • ISBN: 9784525212810
• [Book] Microbiota: Current Research and Emerging Trends (2019)
  • Author(s): Vo Phuoc Tuan, Boldbaatar Gantuya, Takashi Matsumoto and Yoshio Yamaoka
  • Total Pages: 24
  • Publisher: Caister Academic Press
• [Remarks] 大分大学医学部環境・予防医学講座
  • URL: https://oitadepm.com/
• [Remarks] 大分大学 SATREPS
  • URL: https://satreps-oitauniv.com/
• [Remarks] 大分大学医学部環境・予防医学講座
  • URL: http://www.med.oita-u.ac.jp/phealth2/index.html
• [Remarks] 大分大学グローカル感染症研究大分大学
  • URL: https://www.oita-glocal.jp/
• [Remarks] 大分大学国際教育研究推進機構
  • URL: http://in-gear.med.oita-u.ac.jp
• [Remarks] 大分大学医学部環境・予防医学
  • URL: http://www.med.oita-u.ac.jp/phealth2/index.html
• [Remarks] 大分大学国際教育研究推進機構
  • URL: http://in-gear.med.oita-u.ac.jp/
• [Patent(Industrial Property Rights)] ペプチド及びその利用 (2018)
  • Inventor(s): 赤田純子、山岡吉 生、村上和成、塩田 星児
  • Industrial Property Rights Holder: 赤田純子、山岡吉 生、村上和成、塩田 星児
  • Industrial Property Rights Type: 特許
  • Filing Date: 2018
• [Funded Workshop] 「アフリカにおけるピロリ菌感染」国際セミナー：ルワンダおよびケニア共和国にて開催 (2018)