Genome-wide identification of genes for anorexia and their cascade analysis on disease development by functional study

• Project/Area Number: 19101008
• Research Category: Grant-in-Aid for Scientific Research (S)
• Allocation Type: Single-year Grants
• Research Field: Applied genomics
• Research Institution: Tokai University
• Principal Investigator: INOKO Hidetoshi 東海大学, 医学部, 教授 (10101932)
• Co-Investigator(Kenkyū-buntansha): OKA Akira 東海大学, 医学部, 講師 (80384866) ; ENDOH Takaho 独立行政法人理化学研究所, 生命情報基盤研究部門, 研究員 (40384862) ; OHTSUKA Masato 東海大学, 医学部, 講師 (90372945) ; YOSHIHARA Eisaku 東海大学, 医学部, 准教授 (70167063) ; HIRAYAMA Noriaki 東海大学, 医学部, 教授 (70238393)
• Project Period (FY): 2007 – 2011
• Project Status: Completed (Fiscal Year 2011)
• Budget Amount: ¥109,590,000 (Direct Cost: ¥84,300,000、Indirect Cost: ¥25,290,000); Fiscal Year 2011: ¥21,450,000 (Direct Cost: ¥16,500,000、Indirect Cost: ¥4,950,000); Fiscal Year 2010: ¥21,580,000 (Direct Cost: ¥16,600,000、Indirect Cost: ¥4,980,000); Fiscal Year 2009: ¥21,580,000 (Direct Cost: ¥16,600,000、Indirect Cost: ¥4,980,000); Fiscal Year 2008: ¥21,580,000 (Direct Cost: ¥16,600,000、Indirect Cost: ¥4,980,000); Fiscal Year 2007: ¥23,400,000 (Direct Cost: ¥18,000,000、Indirect Cost: ¥5,400,000)
• Keywords: 摂食障害 / マイクロサテライト / 相関解析 / ネットワーク解析 / GWAS / 感受性遺伝子 / 疾患モデルマウス / コンタクチン / シナプトタグミン / NETO / シナプトガミン / シンタキシン / 酵母ツーハイブリッド法 / ゲノムワイド相関解析(GWAS) / シナプス小胞 / 神経伝達物質 / エンドサイトーシス

Research Abstract

An eating disorder is a mental disorder which sharply increased since the late 1990s for people of young age. Its treatment strategies or prognostic methods, however, have yet to be established. In the study described here, we first identified susceptible genes of the disease, based on our genome-wide association analysis with microsatellite markers. To the identified susceptible genes, we applied our high-sensitivity yeast two-hybrid method, followed by immunoprecipitation analysis in mammalian cells. Through these analyses, we found dozens of disease-related interactors, identities of which suggest molecular function of the susceptible genes. We further analyzed one of the susceptible genes by protein-protein interaction assays in details and identified an 83 amino-acid region which is important for both molecular interactions and cellular localization and is, therefore, a good candidate as a drug development target.

Research Products

• [Journal Article] Current understanding of human genetics and genetic analysis of psoriasis (2012)
  • Author(s): Oka A, Mabuchi T, Ozawa A, Inoko H
  • Journal Title: J Dermatol Volume: 39 Pages: 231-241
  • NAID: 10031184877
  • Peer Reviewed
• [Journal Article] Population genetic structure of peninsular Malaysia Malay sub-ethnic groups (2012)
  • Author(s): Hatin WI, Nur-Shafawati AR, Zahri MK, Xu S, Jin L, Tan SG, Rizman-Idid M, Zilfalil BA; HUGO Pan-Asian SNP Consortium
  • Journal Title: PLoS One Volume: 5:6(4) Issue: 4 Pages: e18312-e18312
  • DOI: 10.1371/journal.pone.0018312
  • Peer Reviewed
• [Journal Article] Genetic variation and hitchhiking between structurally polymorphic Alu insertions and HLA-A,-B, and-C alleles and other retroelements within the MHC class I region (2011)
  • Author(s): Kulski JK, Shigenari A, Inoko H
  • Journal Title: Tissue Antigens Volume: 78 Pages: 359-377
  • Peer Reviewed
• [Journal Article] Enforced expression of the transcription factor HOXD3 under the control of the Wnt1 regulatory element modulates cell adhesion properties in the developing mouse neural tube (2011)
  • Author(s): Taniguchi Y, Tanaka O, Sekiguchi M, Takekoshi S, Tsukamoto H, Kimura M, Imai K, Inoko H
  • Journal Title: J Anat Volume: 219 Pages: 589-600
  • Peer Reviewed
• [Journal Article] Exact break point of a 50 kb deletion 8 kb centromeric of the HLA-A locus with HLA-A 24 : 02 : the same deletion observed in other A 24 alleles and A 23 : 01 allele (2011)
  • Author(s): Mitsunaga S, Okudaira Y, Kunii N, Cui T, Hosomichi K, Oka A, Suzuki Y, Homma Y, Sato S, Inoue I, Inoko H
  • Journal Title: Immunogenetics Volume: 63 Pages: 467-474
  • Peer Reviewed
• [Journal Article] Particular human leukocyte antigen alleles are associated with biochemical traits in the Japanese population (2011)
  • Author(s): Mitsunaga S, Homma Y, Narita A, Kashiwase K, Okudaira Y, Shiina Y, Inoue I, Inoko H
  • Journal Title: Hum Immunol Volume: 72 Pages: 566-570
  • Peer Reviewed
• [Journal Article] SLA-DRB1 and-DQB1 genotyping by the PCR-SSOP-Luminex method (2011)
  • Author(s): Ando A, Shigenari A, Ota M, Sada M, Kawata H, Azuma F, Kojima-Shibata C, Nakajoh M, Suzuki K, Uenishi H, Kulski JK, Inoko H
  • Journal Title: Tissue Antigens Volume: 78 Pages: 49-55
  • Peer Reviewed
• [Journal Article] Targeted transgenesis through pronuclear injection of improved vectors into in vitro fertilized eggs (2011)
  • Author(s): Ohtsuka M, Miura H, Nakaoka H, Kimura M, Sato M, Inoko H
  • Journal Title: Transgenic Res Volume: 21 Pages: 225-226
  • Peer Reviewed
• [Journal Article] Which CIDE are you on? Apoptosis and energy metabolism (2011)
  • Author(s): Yonezawa T, Kurata R, Kimura M, Inoko H
  • Journal Title: Mol Biosyst Volume: 7 Pages: 91-110
  • Peer Reviewed
• [Journal Article] Which CIDE are you on? Apoptosis and energy metabolism (2011)
  • Author(s): Yonezawa Tomo; Kurata Riho; Kimura Minoru, et al
  • Journal Title: MOLECULAR BIOSYSTEMS Volume: 7 Issue: 4 Pages: 91-100
  • DOI: 10.1007/s13577-011-0019-y
  • Peer Reviewed
• [Journal Article] NFKBIL1 Confers Resistance to Experimental Autoimmune Arthritis Through the Regulation of Dendritic Cell Functions (2011)
  • Author(s): Chiba T.; Matsuzaka Y.; Warita T., et al
  • Journal Title: SCANDINAVIAN JOURNAL OF IMMUNOLOGY Volume: 73:5 Issue: 5 Pages: 478-485
  • DOI: 10.1111/j.1365-3083.2011.02524.x
  • Peer Reviewed
• [Journal Article] Meta-Analysis Confirms the LCE3C_LCE3B Deletion as a Risk Factor for Psoriasis in Several Ethnic Groups and Finds Interaction with HLA-Cw6 (2011)
  • Author(s): Riveira-Munoz Eva; He Su-Min; Escaramis Georgia, et al
  • Journal Title: JOURNAL OF INVESTIGATIVE DERMATOLOGY Volume: 131:5 Issue: 5 Pages: 1105-1109
  • DOI: 10.1038/jid.2010.350
  • Peer Reviewed
• [Journal Article] Investigation of Association between TLR9 Gene Polymorphisms and VKH in Japanese Patients (2011)
  • Author(s): Ito Ryuta; Ota Masao; Meguro Akira, et al
  • Journal Title: OCULAR IMMUNOLOGY AND INFLAMMATION Volume: 19:3 Issue: 3 Pages: 202-205
  • DOI: 10.3109/09273948.2011.553981
  • Peer Reviewed
• [Journal Article] Particular human leukocyte antigen alleles are associated with biochemical traits in the Japanese population (2011)
  • Author(s): Mitsunaga Shigeki; Homma Yasuhiko; Narita Akira, et al
  • Journal Title: HUMAN IMMUNOLOGY Volume: 72:7 Issue: 7 Pages: 566-570
  • DOI: 10.1016/j.humimm.2011.03.011
  • Peer Reviewed
• [Journal Article] SLA-DRB1 and -DQB1 genotyping by the PCR-SSOP-Luminex method (2011)
  • Author(s): Ando A.; Shigenari A.; Ota M., et al
  • Journal Title: TISSUE ANTIGENS Volume: 78:1 Issue: 1 Pages: 49-55
  • DOI: 10.1111/j.1399-0039.2011.01669.x
  • Peer Reviewed
• [Journal Article] Exact break point of a 50 kb deletion 8 kb centromeric of the HLA-A locus with HLA-A*24:02 : the same deletion observed in other A*24 alleles and A*23:01 allele (2011)
  • Author(s): Mitsunaga Shigeki; Okudaira Yuko; Kunii Nanae, et al
  • Journal Title: IMMUNOGENETICS Volume: 63:8 Issue: 8 Pages: 467-474
  • DOI: 10.1007/s00251-011-0521-0
  • Peer Reviewed
• [Journal Article] Cytochrome P450 genetic polymorphisms influence the serum concentration of calcineurin inhibitors in allogeneic hematopoietic SCT recipients (2011)
  • Author(s): Onizuka M.; Kunii N.; Toyosaki M., et al
  • Journal Title: BONE MARROW TRANSPLANTATION Volume: 46:8 Issue: 8 Pages: 1113-1117
  • DOI: 10.1038/bmt.2010.273
  • Peer Reviewed
• [Journal Article] A novel splicing variant of CADM2 as a protective transcript of psoriasis (2011)
  • Author(s): Hiruma Azusa; Ikeda Shigaku; Terui Tadashi, et al
  • Journal Title: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Volume: 412:4 Issue: 4 Pages: 626-632
  • DOI: 10.1016/j.bbrc.2011.08.013
  • Peer Reviewed
• [Journal Article] Simple cloning strategy using GFPuv gene as positive/negative indicator (2011)
  • Author(s): Miura Hiromi; Inoko Hidetoshi; Inoue Ituro, et al
  • Journal Title: ANALYTICAL BIOCHEMISTRY Volume: 416:2 Issue: 2 Pages: 237-239
  • DOI: 10.1016/j.ab.2011.04.040
  • Peer Reviewed
• [Journal Article] A Systems Genetics Approach Provides a Bridge from Discovered Genetic Variants to Biological Pathways in Rheumatoid Arthritis (2011)
  • Author(s): Nakaoka Hirofumi; Cui Tailin; Tajima Atsushi, et al
  • Journal Title: PLOS ONE Volume: 6:9 Issue: 9 Pages: e25389-e25389
  • DOI: 10.1371/journal.pone.0025389
  • Peer Reviewed
• [Journal Article] Genetic variation and hitchhiking between structurally polymorphic Alu insertions and HLA-A, -B, and -C alleles and other retroelements with in the MHC class I region (2011)
  • Author(s): Kulski J.K.; Shigenari A.; Inoko H.
  • Journal Title: TISSUE ANTIGENS Volume: 78:5 Issue: 5 Pages: 359-377
  • DOI: 10.1111/j.1399-0039.2011.01776.x
  • Peer Reviewed
• [Journal Article] Enforced expression of the transcription factor HOXD3 under the control of the Wnt1 regulatory element modulates cell adhesion properties in the developing mouse neural tube (2011)
  • Author(s): Taniguchi Yasushi; Tanaka Osamu; Sekiguchi Masaki, et al
  • Journal Title: JOURNAL OF ANATOMY Volume: 219:5 Issue: 5 Pages: 589-600
  • DOI: 10.1111/j.1469-7580.2011.01425.x
  • Peer Reviewed
• [Journal Article] Cytotoxic T-lymphocyte antigen 4 haplotype correlates with relapse and survival after allogeneic hematopoietic SCT (2011)
  • Author(s): Murase M.; Nishida T.; Onizuka M., et al
  • Journal Title: BONE MARROW TRANSPLANTATION Volume: 46:11 Issue: 11 Pages: 1444-1449
  • DOI: 10.1038/bmt.2010.319
  • Peer Reviewed
• [Journal Article] GM-CSF-Independent CD1a Expression in Epidermal Langerhans Cells : Evidence from Human CD1A Genome-Transgenic Mice (2011)
  • Author(s): Kobayashi Chisa; Shiina Takashi; Tokioka Atsuko, et al
  • Journal Title: JOURNAL OF INVESTIGATIVE DERMATOLOGY Volume: 132:1 Issue: 1 Pages: 241-244
  • DOI: 10.1038/jid.2011.280
  • Peer Reviewed
• [Journal Article] Current understanding of human genetics and genetic analysis of psoriasis (2011)
  • Author(s): Oka Akira; Mabuchi Tomotaka; Ozawa Akira, et al
  • Journal Title: JOURNAL OF DERMATOLOGY Volume: 39:3 Issue: 3 Pages: 231-241
  • DOI: 10.1111/j.1346-8138.2012.01504.x
  • NAID: 10031184877
  • Peer Reviewed
• [Journal Article] Application of high-resolution, massively parallel pyrosequencing for estimation of haplotypes and gene expression levels of swine leukocyte antigen (SLA) class I genes (2011)
  • Author(s): Kita Yuki F.; Ando Asako; Tanaka Keiko, et al
  • Journal Title: IMMUNOGENETICS Volume: 64:3 Issue: 3 Pages: 187-199
  • DOI: 10.1007/s00251-011-0572-2
  • Peer Reviewed
• [Journal Article] Targeted transgenesis through pronuclear injection of improved vectors into in vitro fertilized eggs (2011)
  • Author(s): Ohtsuka, M., Miura, H., Nakaoka, H., Kimura, M., Sato, M., Inoko, H.
  • Journal Title: Transgenic Research Volume: 21:1 Issue: 1 Pages: 225-226
  • DOI: 10.1007/s11248-011-9505-y
  • Peer Reviewed
• [Journal Article] Comparative genome analysis of the major histocompatibility complex (MHC) class i B/C segments in primates elucidated by genomic sequencing in common marmoset (Callithrix jacchus) (2011)
  • Author(s): Shiina, T., Kono, A., Westphal, N., Suzuki, S., Hosomichi, K., Kita, Y.F, Roos, et al
  • Journal Title: Immunogenetics Volume: 63:8 Issue: 8 Pages: 485-499
  • DOI: 10.1007/s00251-011-0526-8
  • Peer Reviewed
• [Journal Article] IκBL, a novel member of the nuclear IκB family, inhibits inflammatory cytokine expression (2011)
  • Author(s): Chiba T, Miyashita K, Sugoh T, Warita T, Inoko H, Kimura M, Sato T
  • Journal Title: FEBS Letters Volume: 585:22 Issue: 22 Pages: 3577-3581
  • DOI: 10.1016/j.febslet.2011.10.024
  • Peer Reviewed
• [Journal Article] Identification of close relatives in the HUGO Pan-Asian SNP database (2011)
  • Author(s): Yang X, Xu S; HUGO Pan-Asian SNP Consortium; Indian Genome Variation Consortium
  • Journal Title: PLoS One Volume: 6:12 Issue: 12 Pages: 29502-29502
  • DOI: 10.1371/journal.pone.0029502
  • Peer Reviewed
• [Journal Article] Failure to detect significant association between estrogen receptor-alpha gene polymorphisms and endometriosis in Japanese women (2011)
  • Author(s): Matsuzaka Y, Kikuti Y.Y, Izumi S, Goya K, Suzuki T, Cai L, Oka A, Kimura M, et al
  • Journal Title: Environmental Health and Preventive Medicine Volume: PMID:22222969
  • NAID: 10031120517
  • Peer Reviewed
• [Journal Article] Meta-Analysis Confirms the LCE3C-LCE3B Deletion as a Risk Factor for Psoriasis in Several Ethnic Groups and Finds Interaction with HLA-Cw6 (2011)
  • Author(s): Riveira-Munoz E, He SM, Es caramis G, Stuart PE, Huffmeier U, Lee C, Kirby B, Oka A, Giardina E, Liao W, Bergboer J, Kainu K, de Cid R, Munkhbat B, Zeeuwen PL, Armour JA, Poon A, Mabuchi T, Ozawa A, Zawirska A, Burden AD, Barker JN, Capon F, Traupe H, Sun LD, Cui Y, Yin XY, Chen G, Lim HW, Nair RP, Voorhees JJ, Tejasvi T, Pujol R, Munkhtuvshin N, Fischer J, Kere J, Schalkwijk J, Bowcock A, Kwok PY, Novelli G, Inoko H, Ryan AW, Trembath RC, Reis A, Zhang XJ, Elder JT, Estivill X
  • Journal Title: J Invest Dermatol Volume: 131 Pages: 1105-1109
  • Peer Reviewed
• [Journal Article] Cytotoxic T-lymphocyte antigen 4 haplotype correlates with relapse and survival after allogeneic hematopoietic SCT Bone (2011)
  • Author(s): Murase M, Nishida T, Onizuka M, Inamoto Y, Sugimoto K, Imahashi N, Murata M, Miyamura K, Kodera Y, Inoko H, Naoe T
  • Journal Title: Marrow Transplant Volume: Dec 20(epub) Pages: 1-6
  • Peer Reviewed
• [Journal Article] NFKBIL1 confers resistance to experimental autoimmune arthritis through the regulation of dendritic cell functions. (2011)
  • Author(s): Chiba T, Matsuzaka Y, Warita T, Sugoh T, Miyashita K, Tajima A, Nakamura M, Inoko H, Sato T, Kimura M
  • Journal Title: Scand J Immunol Volume: 73 Pages: 478-485
  • Peer Reviewed
• [Journal Article] Primordial linkage of β2-microglobulin to the MHC (2011)
  • Author(s): Ohta Y, Shiina T, Lohr RL, Hosomichi K, Pollin TI, HeistEJ, Suzuki S, Inoko H, Flajnik MF
  • Journal Title: J Immunol Volume: 186 Pages: 3563-3567
  • Peer Reviewed
• [Journal Article] Toll-like receptor 2 (TLR2) gene polymorphisms are not associated with sarcoidosis in the Japanese population. (2011)
  • Author(s): Sato M, Kawagoe T, Meguro A, Ota M, Katsuyama Y, Ishihara M, Namba K, Kitaichi N, Morimoto S, Kaburaki T, Ando Y, Takenaka S, OhnoS, Inoko H, Mizuki N
  • Journal Title: Mol Vis Volume: 17 Pages: 731-736
  • Peer Reviewed
• [Journal Article] Targeted transgenesis through pronuclear injection of improved vectors into in vitro fertilized eggs. (2011)
  • Author(s): Ohtsuka M, Miura H, Nakaoka H, Kimura M, Sato M, Inoko H.
  • Journal Title: Transgenic Res Volume: Mar 25 Pages: 1-2
  • Peer Reviewed
• [Journal Article] Pronuclear injection-based mouse targeted transgenesis for reproducible and highly efficient transgene expression (2010)
  • Author(s): Ohtsuka M, Ogiwara S, Miura H, Mizutani A, Warita T, Sato M, Imai K, Hozumi K, Sato T, Tanaka M, Kimura M, Inoko H
  • Journal Title: Nucleic Acids Res Volume: 38
  • Peer Reviewed
• [Journal Article] TRIM39 and RNF39 are associated with Behcet's disease independently of HLA-B 51 and-A 26 (2010)
  • Author(s): Kurata R, Nakaoka H, Tajima A, Hosomichi K, Shiina T, Meguro A, Mizuki N, Ohono S, Inoue I, Inoko H
  • Journal Title: Biochem Biophys Res Commun Volume: 401 Pages: 533-537
  • Peer Reviewed
• [Journal Article] Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behcet's disease susceptibility loci (2010)
  • Author(s): Mizuki N, Meguro A, Ota M, Ohno S, Shiota T, Kawagoe T, Ito N, Kera J, Okada E, Yatsu K, Song YW, Lee EB, Kitaichi N, Namba K, Horie Y, Takeno M, Sugita S, Mochizuki M, Bahram S, Ishigatsubo Y, Inoko H
  • Journal Title: Nature Genet Volume: 42 Pages: 703-706
  • Peer Reviewed
• [Journal Article] Flow cytometric identification of CD93 expression on naive T lymphocytes(CD4(+) CD45RA(+) cells) in human neonatal umbilical cord blood (2010)
  • Author(s): Ikewaki N, Yamao H, Kulski JK, Inoko H
  • Journal Title: J Clin Immunol Volume: 30 Pages: 723-733
  • Peer Reviewed
• [Journal Article] Polymorphic major histocompatibility complex class II Alu insertions at five loci and their association with HLA-DRB1 and-DQB1 in Japanese and Caucasians (2010)
  • Author(s): Kulski JK, Shigenari A, Shiina T, Inoko H
  • Journal Title: Tissue Antigens Volume: 76 Pages: 35-47
  • Peer Reviewed
• [Journal Article] Individuals susceptible to lung adenocarcinoma defined by combined HLA-DQA1 and TERT genotypes. (2010)
  • Author(s): Kohno T, Kunitoh H, Shimada Y, Shiraishi K, Ishii Y, Goto K, Ohe Y, Nishiwaki Y, Kuchiba A, Yamamoto S, Hirose H, Oka A, Yanagitani N, Saito R, Inoko H, Yokota J
  • Journal Title: Carcinogenesis Volume: 31 Pages: 834-841
  • Peer Reviewed
• [Journal Article] Polymorphic SVA retrotransposons at four loci and their association with classical HLA class I alleles in Japanese, Caucasians and African Americans. (2010)
  • Author(s): Kulski JK, Shigenari A, Inoko H
  • Journal Title: Immunogenetics Volume: 62 Pages: 211-230
  • Peer Reviewed
• [Journal Article] Mapping of susceptibility locus for endometriosis within the HLA region using microsatellite markers in Japanese women. (2010)
  • Author(s): Matsuzaka Y, Kikuti YY, Izumi S, Suzuki T, Cai LY, Goya K, Inoko H, Makino T, Kulski JK, Kimura M
  • Journal Title: Tissue Antigens Volume: 75 Pages: 65-67
  • Peer Reviewed
• [Journal Article] Anti-human very late antigen-alpha4 (CD49d) monoclonal antibody (BU49) cross-reacts with the canine B-cell leukemia cell line GL-1, resulting in the induction of homotypic cell aggregation. (2010)
  • Author(s): Ikewaki N, Nakaichi M, Mizuno T, Takamura N, Tokunaga J, Ogata K, Inoko H, Otsu R
  • Journal Title: Cell Immunol Volume: 263 Pages: 55-64
  • Peer Reviewed
• [Journal Article] Analysis of microsatellite polymorphisms within the GLC1F locus in Japanese patients with normal tension glaucoma. (2010)
  • Author(s): Murakami K, Meguro A, Ota M, Shiota T, Nomura N, Kashiwagi K, Mabuchi F, Iijima H, Kawase K, Yamamoto T, Nakamura M, Negi A, Sagara T, Nishida T, Inatani M, Tanihara H, Aihara M, Araie M, Fukuchi T, Abe H, Higashide T, Sugiyama K, Kanamoto T, Kiuchi Y, Iwase A, Ohno S, Inoko H, Mizuki N
  • Journal Title: Mol Vis Volume: 16 Pages: 462-466
  • Peer Reviewed
• [Journal Article] Impact of highly conserved HLA haplotype on acute graft-versus-host disease. (2010)
  • Author(s): Morishima S, Ogawa S, Matsubara A, Kawase T, Nannya Y, Kashiwase K, Satake M, Saji H, Inoko H, Kato S, Kodera Y, Sasazuki T, Morishima Y
  • Journal Title: Blood Volume: 115 Pages: 4664-4670
  • Peer Reviewed
• [Journal Article] Genome-wide association study of normal tension glaucoma : common variants in SRBD1 and ELOVL5 contribute to disease susceptibility. (2010)
  • Author(s): Writing Committee for the Normal Tension Glaucoma Genetic Study Group of Japan Glaucoma Society, Meguro A, Inoko H, Ota M, Mizuki N, Bahram S
  • Journal Title: Ophthalmology Volume: 117 Pages: 1331-1338
  • Peer Reviewed
• [Journal Article] Polymorphic major histocompatibility complex class II Alu insertions at five loci and their association with HLA-DRB1 and -DQB1 in Japanese and Caucasians. (2010)
  • Author(s): Kulski JK, Shigenari A, Shiina T, Inoko H
  • Journal Title: Tissue Antigens Volume: 76 Pages: 35-47
  • Peer Reviewed
• [Journal Article] Flow cytometric identification of CD93 expression on naive T lymphocytes (CD4(+)CD45RA (+) cells) in human neonatal umbilical cord blood. (2010)
  • Author(s): Ikewaki N, Yamao H, Kulski JK, Inoko H
  • Journal Title: J Clin Immunol Volume: 30 Pages: 723-733
  • Peer Reviewed
• [Journal Article] Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behcet's disease susceptibility loci. (2010)
  • Author(s): Mizuki N, Meguro A, Ota M, Ohno S, Shiota T, Kawagoe T, Ito N, Kera J, Okada E, Yatsu K, Song YW, Lee EB, Kitaichi N, Namba K, Horie Y, Takeno M, Sugita S, Mochizuki M, Bahram S, Ishigatsubo Y, Inoko H
  • Journal Title: Nature Genet Volume: 42 Pages: 703-706
  • Peer Reviewed
• [Journal Article] Genome wide screen identifies microsatellite markers associated with acute adverse effects following radiotherapy in cancer patients. (2010)
  • Author(s): Michikawa Y, Suga T, Ishikawa A, Hayashi H, Oka A, Inoko H, Iwakawa M, Imai T
  • Journal Title: BMC Med Genet Volume: 11 Pages: 123-123
  • Peer Reviewed
• [Journal Article] TRIM39 and RNF39 are associated with Behcet's disease independently of HLA-B*51 and -A*26 (2010)
  • Author(s): Kurata R, Nakaoka H, Tajima A, Hosomichi K, Shiina T, Meguro A, Mizuki N, Ohono S, Inoue I, Inoko H
  • Journal Title: Biochem Biophys Res Commun Volume: 401 Pages: 533-537
  • Peer Reviewed
• [Journal Article] Pronuclear injection-based mouse targeted transgenesis for reproducible and highly efficient transgene expression. (2010)
  • Author(s): Ohtsuka M, Ogiwara S, Miura H, Mizutani A, Warita T, Sato M, Imai K, Hozumi K, Sato T, Tanaka M, Kimura M, Inoko H
  • Journal Title: Nucleic Acids Res Volume: 38
  • Peer Reviewed
• [Journal Article] Mitochondrial DNA diversity among three subpopulations of cynomolgus macaques (Macaca fascicularis) originating from the Indochinese region. (2010)
  • Author(s): Shiina T, Tanaka K, Katsuyama Y, Otabe K, Sakamoto K, Kurata M, Nomura M, Yamanaka H, Nakagawa H, Inoko H, Ota.M
  • Journal Title: Exp Anim Volume: 59 Pages: 567-578
  • NAID: 130000419251
  • Peer Reviewed
• [Journal Article] Genotyping HLA-DRB1 and HLA-DQB1 alleles in Japanese patients with normal tension glaucoma. (2010)
  • Author(s): Suzuki M, Meguro A, Ota M, Nomura E, Kato T, Nomura N, Kashiwagi K, Mabuchi F, lijima H, Kawase K, Yamamoto T, Nakamura M, Negi A, Sagara T, Nishida T, Inatani M, Tanihara H, Aihara M, Araie M, Fukuchi T, Abe H, Higashide T, Sugiyama K, Kanamoto T, Kiuchi Y, Iwase A, Ohno S, Inoko H, Mizuki N
  • Journal Title: Mol Vis Volume: 16 Pages: 1874-1879
  • Peer Reviewed
• [Journal Article] Cytochrome P450 genetic polymorphisms influence the serum concentration of calcineurin inhibitors in allogeneic hematopoietic SCT recipients (2010)
  • Author(s): Onizuka M, Kunii N, Toyosaki M, Machida S, Ohgiya D, Ogawa Y, Kawada H, Inoko H, Ando K
  • Journal Title: Bone Marrow Transplant Volume: Nov 22(epub) Pages: 1-5
  • Peer Reviewed
• [Journal Article] Association analysis of Toll-like receptor 7 gene polymorphisms and Behcet's disease in Japanese patients (2010)
  • Author(s): Sada T, Ota M, Katsuyama Y, Meguro A, Nomura E, Uemoto R, Nishide T, Okada E, Ohno S, Inoko H, Mizuki N
  • Journal Title: Hum Immunol Volume: 72 Pages: 269-272
  • Peer Reviewed
• [Journal Article] Nutritional and hormonal regulation of uncoupling protein 2 (2009)
  • Author(s): Yonezawa T, Kurata R, Hosomichi K, Kono A, Kimura M, Inoko H
  • Journal Title: IUBMB Life Volume: 61 Pages: 1123-1131
  • Peer Reviewed
• [Journal Article] Trans-species polymorphism of the Mhc class II DRB-like gene in banded penguins(genus Spheniscus) (2009)
  • Author(s): Kikkawa EF, Tsuda TT, Sumiyama D, Naruse TK, Fukuda M, Kurita M, Wilson RP, LeMaho Y, Miller GD, Tsuda M, Murata K, Kulski JK, Inoko H
  • Journal Title: Immunogenetics Volume: 61 Pages: 341-352
  • Peer Reviewed
• [Journal Article] PKC Delta and Epsilon in drug targeting and therapeutics (2009)
  • Author(s): Yonezawa T, Kurata R, Kimura M, Inoko H
  • Journal Title: Recent Patents on DNA & Gene Sequences Volume: 3 Pages: 96-101
  • Peer Reviewed
• [Journal Article] Recombinant DNA technologies for construction of precisely designed transgene constructs (2009)
  • Author(s): Ohtsuka M, Kimura M, Tanaka M, Inoko H
  • Journal Title: Curr Pharm Biotechnol Volume: 10 Pages: 244-251
  • Peer Reviewed
• [Journal Article] Detecting linkage between a trait and a marker in a random mating population without pedigree record (2009)
  • Author(s): Mano S, Endo TA, Oka A, Ozawa A, Gojobori T, Inoko H
  • Journal Title: PLoS ONE Volume: 4
  • Peer Reviewed
• [Journal Article] HLA-A allele associations with viral MER9-LTR nucleotide sequences at two distinct loci within the MHC alpha block (2009)
  • Author(s): Kulski JK, Shigenari A, Shiina T, Hosomichi K, Yawata M, Inoko H
  • Journal Title: Immunogenetics Volume: 61 Pages: 257-270
  • Peer Reviewed
• [Journal Article] Detecting linkage between a trait and a marker in a random mating population without pedigree record (2009)
  • Author(s): Mano S, Endo A, Oka A, Ozawa A, Go jobori T, Inoko H
  • Journal Title: PLoS ONE 4
  • Peer Reviewed
• [Journal Article] Indian Genome Variation Consortium (他87名) : Mapping human genetic diversity in Asia (2009)
  • Author(s): HUGO Pan-Asian SNP Consortium, Abdulla MA, Ahmed I, Assawamakin A, Inoko H
  • Journal Title: Science 326 Pages: 1541-1545
  • Peer Reviewed
• [Journal Article] Japanese Genetic Research Group for Eating Disorders (JGRED), Shirasawa S : Identification of novel candidate loci for anorexia nervosa at 1q41 and 11q22 in Japanese by a genome-wide association analysis with microsatellite markers (2009)
  • Author(s): Nakabayashi K, Komaki G, Tajima A, Ando T, Ishikawa M, Nomoto J, Hata K, Oka A, Inoko H, Sasazuki T;
  • Journal Title: J Hum Genet 54 Pages: 531-537
  • Peer Reviewed
• [Journal Article] The genetic relationship among Iranian ethnic groups : an anthropological view based on HLAclass II gene polymorphism. (2009)
  • Author(s): Farjadian S, Ota M, Inoko H, Ghaderi A
  • Journal Title: Mol Biol Rep 36 Pages: 1943-1950
  • Peer Reviewed
• [Journal Article] HLA-A allele associations with viral MER9-LTR nucleotide sequences at two distinct loci within the MHC alpha block. (2009)
  • Author(s): Kulski JK, Shigenari A, Shiina T, Hosomichi K, Yawata M, Inoko H
  • Journal Title: Immunogenetics 61 Pages: 257-270
  • Peer Reviewed
• [Journal Article] Complex divergence at a microsatellite marker C1_2_5 in the lineage of HLA-Cw/-B haplotype. (2009)
  • Author(s): Shichi D, Ota M, Katsuyama Y, Inoko H, Naruse TK, Kimura A
  • Journal Title: J Hum Genet 54 Pages: 224-229
  • NAID: 10030730018
  • Peer Reviewed
• [Journal Article] PKC Delta and Epsilon in drug targeting and therapeutics. (2009)
  • Author(s): Yonezawa T, Kurata R, Kimura M, Inoko H
  • Journal Title: Recent Patents on DNA & Gene Sequences 3 Pages: 96-101
  • Peer Reviewed
• [Journal Article] Trans-species polymorphism of the Mhc class II DRB-like gene in banded penguins (genus Spheniscus). (2009)
  • Author(s): Kikkawa EF, Tsuda TT, Sumiyama D, Naruse TK, Inoko H, et al.
  • Journal Title: Immunogenetics 61 Pages: 341-352
  • Peer Reviewed
• [Journal Article] Assessment of chromosome 19 for genetic association in severe chronic periodontitis. (2009)
  • Author(s): Tabeta K, Shimada Y, Tai H, Ishihara Y, Noguchi T, Soga Y, Inoko H, et al.
  • Journal Title: J Periodontol 80 Pages: 663-671
  • Peer Reviewed
• [Journal Article] Association of TLR4 polymorphisms with Behcet's disease in a Korean population. (2009)
  • Author(s): Horie Y, Meguro A, Ota M, Kitaichi N, Inoko H, et al.
  • Journal Title: Rheumatology 48 Pages: 638-642
  • Peer Reviewed
• [Journal Article] Identification of MICA as a Susceptibility Gene for Pulmonary Mycobacterium avium Complex Infection. (2009)
  • Author(s): Shojima J, Tanaka G, Keicho N, Tamiya G, Ando S, Oka A, et al, Inoko H.
  • Journal Title: J Infect Dis 199 Pages: 1707-1715
  • Peer Reviewed
• [Journal Article] HLA-B^* 15 subtypes in Burmese population by sequence-based typing. (2009)
  • Author(s): Kongmazoeng C, Romphruk A, Ruangwerayut R, Paupairoj C, Inoko H, et al.
  • Journal Title: Tissue Antigens 74 Pages: 164-167
  • Peer Reviewed
• [Journal Article] Evaluation of PTPN22 polymorphisms and Vogt-Koyanagi-Harada disease in Japanese patients. (2009)
  • Author(s): Horie Y, Kitaichi N, Katsuyama Y, Yoshida K, Miura T, Ota M, Inoko H, et al.
  • Journal Title: Mol Vis. 15 Pages: 1115-1119
  • NAID: 120001415121
  • Peer Reviewed
• [Journal Article] Megakaryoblastic leukemia factor-1 gene in the susceptibility to coronary artery disease. (2009)
  • Author(s): Hinohara K, Nakajima T, Yasunami M, Houda S, Sasaoka T, Yamamoto K, Lee BS, Inoko H, et al.
  • Journal Title: Hum Genet 126 Pages: 539-547
  • Peer Reviewed
• [Journal Article] MHC class I A loci polymorphism and diversity in three Southeast Asian populations of cynomolgus macaque. (2009)
  • Author(s): Kita YF, Hosomichi K, Kohara S, Itoh Y, Ogasawara K, Tsuchiya H, Ioko H, et al.
  • Journal Title: Immunogenetics 61 Pages: 635-468
  • Peer Reviewed
• [Journal Article] Investigation of the association between the GLC3A locus and normal tension glaucoma in Japanese patients by microsatellite analysis. (2009)
  • Author(s): Ikamio M, Meguro A, Ota M, Nomura N, Kashiwagi K, Mabuchi F, Inoko H, et al.
  • Journal Title: Clin Ophthalmol 2009 Pages: 183-188
  • Peer Reviewed
• [Journal Article] Association of microsatellite polymorphisms of the GPDS1 locus with normal tension glaucoma in the Japanese population. (2009)
  • Author(s): Nakamura K, Ota M, Meguro A, Nomura N, Kashiwagi K, Mabuchi F, et al.
  • Journal Title: Clin Ophthalmol 3 Pages: 307-312
  • Peer Reviewed
• [Journal Article] Identification of novel candidate loci for anorexia nervosa at 1q41 and 11q22 in Japanese by agenome-wide association analysis with microsatellite markers. (2009)
  • Author(s): Nakabayashi K, Komaki G, Tajima A, Ando T, Oka A, Inoko H, et al.
  • Journal Title: J Hum Genet 54 Pages: 531-537
  • Peer Reviewed
• [Journal Article] Polymorphisms of NKG2D ligands : diverse RAET1/ULBP genes in northeastern Thais. (2009)
  • Author(s): Romphruk AV, Romphruk A, Naruse TK, Inoko H, Leelayuwat C.
  • Journal Title: Immunogenetics. 61
  • Peer Reviewed
• [Journal Article] A novel system of polymorphic and diverse NK cell receptors in primates. (2009)
  • Author(s): Averdam A, Petersen B, Rosner C, Neff J, Roos C, Inoko H, et al.
  • Journal Title: PLoS Genet 5
  • Peer Reviewed
• [Journal Article] Genetics of Behcet's disease inside and outside the MHC. (2009)
  • Author(s): Meguro A, Inoko H, Ota M, Katsuyama Y, Oka A, Okada E, et al.
  • Journal Title: Ann Rheum Dis 69:04:00 Pages: 747-754
  • Peer Reviewed
• [Journal Article] Nutritional and hormonal regulation of uncoupling protein 2. (2009)
  • Author(s): Yonezawa T, Kurata R, Hosomichi K, Kono A, Kimura M, Inoko H.
  • Journal Title: IUBMB Life 61 Pages: 1123-1131
  • Peer Reviewed
• [Journal Article] Indian Genome Variation Consortium : Mapping human genetic diversity in Asia. (2009)
  • Author(s): HUGO Pan-Asian SNP Consortium, Abdulla MA, Ahmed I, et al.
  • Journal Title: Science 326 Pages: 1541-1545
  • Peer Reviewed
• [Journal Article] Lack of association between toll-like receptor 4 gene polymorphisms and sarcoidosis-related uveitis in Japan. (2009)
  • Author(s): Asukata Y, Ota M, Meguro A, Katsuyama Y, Ishihara M, Inoko H, et al.
  • Journal Title: Mol Vis 15 Pages: 2673-2682
  • Peer Reviewed
• [Journal Article] 乾癬のマイクロサテライトによるゲノムワイド関連解析 (2009)
  • Author(s): 岡晃、猪子英俊
  • Journal Title: 実験医学(疾患いでんしの探索と超高速シークエンス増刊号) 27 Pages: 80-85
  • Peer Reviewed
• [Journal Article] New susceptibility locus for high myopia is linked to the uromodul in-like1(UMODL1)gene region on chromosome21q22.3. (2009)
  • Author(s): Nishizaki R. Ota M. lnoko H. Meguro A. Shiota T, et al
  • Journal Title: Eye 23 : 1 Pages: 222-229
  • Peer Reviewed
• [Journal Article] An evolutionary origin and selection process of goldfish. (2009)
  • Author(s): Komiyama T, Kobayashi H, Tateno Y, Inoko H, et al
  • Journal Title: Gene 430 Pages: 5-11
  • Peer Reviewed
• [Journal Article] The HLA genomic loci map : expression, interaction, diversity anddisease. (2009)
  • Author(s): Shiina T, Hosomichi K, Inoko H, Kulski JK
  • Journal Title: J Hum Genet 54 Pages: 15-39
  • Peer Reviewed
• [Journal Article] Investigation of the association between Toll-like receptor 2 genepolymorphisms and Behcet's disease in Japanese patients. (2009)
  • Author(s): Tomiyama R, Meguro A, Ota M, Katsuyama Y, Inoko H, et al
  • Journal Title: Hum Immunol 70 Pages: 41-44
  • Peer Reviewed
• [Journal Article] Japan Marrow Donation Program (JMDP) : Exploration of the genetic basis of GVHD by genetic association studies. (2009)
  • Author(s): Ogawa S, Matsubara A, Onizuka M, Kashiwase K, Inoko H, et al
  • Journal Title: Biol Blood Marrow Transplant. 5(1 Suppl) Pages: 39-41
  • Peer Reviewed
• [Journal Article] Recombinant DNA technologies for construction of precisely designed transgene constructs. (2009)
  • Author(s): Ohtsuka M, Kimura M, Tanaka M, Inoko H
  • Journal Title: Curr Pharm Biotechnol 10 Pages: 244-251
  • Peer Reviewed
• [Journal Article] Complex divergence at a microsatellite marker C1_2_5 in the lineage of HLA-Cw/-B haplotype. (2009)
  • Author(s): Shichi D, Ota M, Katsuyama Y, Inoko H, et al
  • Journal Title: J Hum Genet. Epub ahead of print
  • NAID: 10030730018
  • Peer Reviewed
• [Journal Article] Genome-wide association analysis with selective genotyping identifies candidate loci for adult height at 8q21.13 and 15q22.33-q23 in Mongolians (2008)
  • Author(s): Kimura T, Kobayashi T, Munkhbat B, Oyungerel G, Bilegtsaikhan T, Anar D, Jambaldorj J, Munkhsaikhan S, Munkhtuvshin N, Hayashi H, Oka A, Inoue I, Inoko H
  • Journal Title: Hum Genet Volume: 123 Pages: 655-660
  • Peer Reviewed
• [Journal Article] A genome-wide association scan for asthma in a general Australian population (2008)
  • Author(s): Hui J, Oka A, James A, Palmer LJ, Musk AW, Beilby J, Inoko H
  • Journal Title: Hum Genet Volume: 123 Pages: 297-306
  • Peer Reviewed
• [Journal Article] A genome-wide association scan for asthma in a general Australian population. (2008)
  • Author(s): Hui J. Oka A. James A. Palmer LJ. Musk AW. Inoko H, et al
  • Journal Title: Hum Genet 123 Pages: 297-306
  • Peer Reviewed
• [Journal Article] Association of the toll-like receptor 4 gene polymorphisms with Behcet's disease. (2008)
  • Author(s): Mequro A Ota M. Katsuyama Y, Oka A, lnoko H, et al
  • Journal Title: Ann Rheum Dis 67 Pages: 725-727
  • Peer Reviewed
• [Journal Article] Major histocompatibility complex (Mhc) class lb gene duplications, organization and expression patterns in mouse strain C57BL/6. (2008)
  • Author(s): Ohtsuka M. lnoko H. Kulski J K, Yoshimura S
  • Journal Title: BMC Genomics 9 Pages: 178-192
  • Peer Reviewed
• [Journal Article] Genome-wide association analysis with selective genotyping identifies candidate loci for adult height at 8q21.13 and 15q22.33-q23 in Mongolians. (2008)
  • Author(s): Kimura T. Kobayashi T. Munkhbat B Oyungerel G, Inok H, et al
  • Journal Title: Hum Genet 123 Pages: 655-660
  • Peer Reviewed
• [Journal Article] Microsatellite diversity and crossover regions within homozygous and heterozygous SLA haplotypes of different pig breeds. (2008)
  • Author(s): Ando A. Uenishi H. Kawata H, Tanaka-Matsuda M. lnoko H, at al
  • Journal Title: Immunogenetics 60 Pages: 399-407
  • Peer Reviewed
• [Journal Article] The amphioxus genome illuminates vertebrate origins and cephalo chordate biology. (2008)
  • Author(s): Holl, LZ. Albalat R. Azumi K, Benito-Gutierrez E, lnoko H, at al
  • Journal Title: Genome Res 18 Pages: 1100-1111
  • Peer Reviewed
• [Journal Article] Association of toll-like receptor 4 gene polymorphisms with normaltension glaucoma. (2008)
  • Author(s): Shibuva E. Meguro A, Ota M. Kashiwaqi K, lnoko H, at al
  • Journal Title: Invest Ophthalmol Vis Sci 49 Pages: 4453-4457
  • Peer Reviewed
• [Journal Article] Human endogenous retrovirus (HERVK9) structural polymorphism with haplotvpic HLA-A allelic associations. (2008)
  • Author(s): Kulski JK, Shigenari A, Shiina S, Ota M, Inoko H, et al
  • Journal Title: Genetics 108 Pages: 446-457
  • Peer Reviewed
• [Journal Article] Re-evaluation of heterogeneity in HLA-B*510101 associated with Behcet's disease. (2008)
  • Author(s): Takemoto Y. Naruse T. Namba K. Kitaichi N. lnoko H, et al
  • Journal Title: Tissu Antigens 72 Pages: 347-353
  • Peer Reviewed
• [Journal Article] Paternity determination of captive bottlenose dolphins (Tursiops truncatus)using microsatellite DNA analysis. (2008)
  • Author(s): Sumiyama D. Kitamura S. Terasawa F, Hori Y. lnoko H, et al
  • Journal Title: J Vet Med Sci 70 Pages: 711-713
  • Peer Reviewed
• [Journal Article] Contribution of mutation, recombination, and gene conversion to chicken MHC-B haplotype diversity. (2008)
  • Author(s): Hosomichi K. Miller MM. Goto RM. Wang Y. lnoko H, et al
  • Journal Title: J lmmunol 181 Pages: 3393-3399
  • Peer Reviewed
• [Journal Article] Microsatellite analysis of the GLC1B locus on chromosome 2 points to NCK2 as a new candidate gene for normal tension glaucoma. (2008)
  • Author(s): Akivama M, Yatsu K, Ota M, Katsuyama Y, lnoko H, et al
  • Journal Title: Br J Ophthalmol 92 Pages: 1293-1296
  • Peer Reviewed
• [Journal Article] The genetic relationship among lranian ethnic groups : an anthropological view based on HLA class II gene polvmorphism. (2008)
  • Author(s): Farjadian s, Ota M, lnoko H, Ghaderi A
  • Journal Title: Mol Biol Rep
  • Peer Reviewed
• [Journal Article] HLAmismatch combinations associated with decreased risk of relapse ; lmplications for molecular mechanism (2008)
  • Author(s): Kawase T, Matsuo K, kashi wases K, lnoko H, et al
  • Journal Title: Blood
  • Peer Reviewed
• [Journal Article] Assignment of the SLA alleles and reproductive potential of selective breeding Duroc pig lines. (2008)
  • Author(s): Soe OK, Ohba Y, Imaeda N, Nishii N, lnoko H, et al
  • Journal Title: Xenotransplantation 15 Pages: 390-397
  • Peer Reviewed
• [Journal Article] Modulation of some cell surface antigens in the monocyte-like cell line U937 in response to β-1, 3-1, 6 gulucan derived from Aureobasidium pullulans. (2008)
  • Author(s): Ikewaki N, Tamauchi H, Inoko H
  • Journal Title: Journal of Kyushu University of Healthand Welfare 9 Pages: 81-91
  • Peer Reviewed
• [Journal Article] 乾癬のマイクロサテライトによるゲノムワイド関連解析 (2008)
  • Author(s): 岡晃, 猪子英俊
  • Journal Title: 医学のあゆみ(臨床ゲノム研究特集号) 225 Pages: 791-797
  • Peer Reviewed
• [Journal Article] Four-digit allele genotyping of HLA-A and HLA-B genes in Japanese patients with Behcet's disease(BD)by a PCR-SSOP-luminexmethod and stratification analysis according to each major symptom of BD. (2008)
  • Author(s): Kamiishi T. Itoh Y. Meguro A, Nishida T, Inoko H, et al
  • Journal Title: 日本眼科会雑誌 112 Pages: 451-458
  • NAID: 10021292413
  • Peer Reviewed
• [Journal Article] Donner killer immunoglobulin-like receptor(KIR)genotype-patient cognate KIR lgand combination and antithymocyte globulin preadministration are critical factors in outcome of HLA-C-KIR ligand-mismatched T Cell-replete unrelated bone marrow transplantation. (2008)
  • Author(s): Yabe T, Matsuo T, Hirayasu K, Kashiwase K, Kawamura-Ishii S, Tanaka H, Ogawa A, Takana shi M, Satake M, Nakajima K, Tokunaga K, Inoko H, Saji H, Ogawa S, Juji T, Sasazuki T, Kodera Y, Morishima
  • Journal Title: Biology of Blood and Marrow Transplantation (BBMT) 14 Pages: 75-87
  • Peer Reviewed
• [Journal Article] Decrease in CD93(C1qRp) expression in a human monocyte cell line(U937) treated with various apoptosis-inducing chemical substances (2007)
  • Author(s): Ikewaki N, Tamauchi H, Inoko H
  • Journal Title: Microbiol Immunol Volume: 51 Pages: 1189-1200
  • Peer Reviewed
• [Journal Article] Immunological actions of Sophyβ-Gllucan(β-1, 3-1, 6 Gulucan), currently available commercially as a health food supplement (2007)
  • Author(s): Ikewaki N, Fujii N, Onaka T, Ikewaki S, Inoko H
  • Journal Title: Microbiol Immunol Volume: 51 Pages: 861-873
  • Peer Reviewed
• [Journal Article] High-resolution mapping for essential hypertension using microsatellite markers (2007)
  • Author(s): Yatsu K, Mizuki N, Hirawa N, Oka A, Itoh N, Yamane T, Ogawa M, Shiwa T, Tabara Y, Ohno S, Soma M, Hata A, Nakao K, Ueshima H, Ogihara T, Tomoike H, Miki T, Kimura A, Mano S, Kulski JK, Umemura S, Inoko H
  • Journal Title: Hypertension Volume: 49 Pages: 446-452
  • Peer Reviewed
• [Journal Article] Microsatellite markers for genome-wide association studies (2007)
  • Author(s): Bahram S, Inoko H
  • Journal Title: Nature Reviews Genetics Volume: 8 Pages: 164-164
  • Peer Reviewed
• [Journal Article] A BAC-based contig map of the cynomolgus macaque(Macaca fascicularis) major histocompatibility complex genomic region (2007)
  • Author(s): Watanabe A, Shiina T, Shimizu S, Hosomichi K, Yanagiya K, Kita YF, Kimura T, Soeda E, Torii R, Ogasawara K, Kulski JK, Inoko H
  • Journal Title: Genomics Volume: 89 Pages: 402-412
  • Peer Reviewed
• [Journal Article] Mapping of susceptibility and protective loci for acute GVHD in unrelated HLA-matched bone marrow transplantation donors and recipients using 155 microsatellite markers on chromosome 22 (2007)
  • Author(s): Kikuchi T, Naruse TK, Onizuka M, Li S, Kimura T, Oka A, Morishima Y, Kulski JK, Ichimiya S, Sato N, Inoko H
  • Journal Title: Immunogenetics Volume: 59 Pages: 99-108
  • Peer Reviewed
• [Journal Article] One-step generation of recombineering constructs by asymmetric-end ligation and negative selection (2007)
  • Author(s): Ohtsuka M, Mizutani A, Kikuti YY, Kulski JK, Sato M, Kimura M, Tanaka M, Inoko H
  • Journal Title: Anal Biochem Volume: 360 Pages: 306-308
  • Peer Reviewed
• [Journal Article] Single nucleotide polymorphism detection by polymerase chain reaction-restriction fragment length polymorphism (2007)
  • Author(s): Ota M, Fukushima H, Kulski JK, Inoko H
  • Journal Title: Nature Protoc 2 Pages: 2857-2864
  • Peer Reviewed
• [Journal Article] Single nucleotide polymorphism detection by polymerase chain reaction-restriction fragment length polymorphism (2007)
  • Author(s): Ota M, Fukushima H, Kulski JK, Inoko H
  • Journal Title: Nature Protoc 11 Pages: 2857-2864
  • Peer Reviewed
• [Journal Article] Microsatellite markers for genome-wide association studies. (2007)
  • Author(s): Bahram S, Inoko H
  • Journal Title: Nature Reviews Genetics 8 Pages: 164-164
  • Peer Reviewed
• [Journal Article] Synergistic association of mitochondrial uncoupling protein (UCP) genes with schizophrenia. (2007)
  • Author(s): Yasuno K, Ando S, Misumi S, Makino S, Kulski JK, Muratake T, Kaneko N, Amagane H, Someya T, Inoko H, Suga H, Kanemoto K, Tamiya G
  • Journal Title: Am J Med Genet B Neuropsychiatr Genet ochem 144 Pages: 250-253
  • Peer Reviewed
• [Journal Article] Two critical genes (HLA-DRB1 and ABCF1)in the HAL region are associated with the susceptibility to autoimmune pancreatitis (2007)
  • Author(s): Ota M, Katsuyama Y, Hamano H, Umemura T, Kimura A, Yoshizawa K, Kiyosawa K, Fukushima H, Bahram S, Inoko H, Kawa S
  • Journal Title: Immunogenetics 59 Pages: 45-52
  • Peer Reviewed
• [Journal Article] One-step generation of recombineering constructs by asymmetric-end ligation and negative selection (2007)
  • Author(s): Ohtsuka M, Mizutani A, Kikuti YY, Knlski JK, Sato M, Kimura M, Tanaka M, Inoko H
  • Journal Title: Anal Biochem 360 Pages: 306-308
  • Peer Reviewed
• [Journal Article] Mapping of susceptibility and protective loci for acute GVHD in unrelated HLA-matched bone marrow transplantation donors and recipients using 155 microsatellite markers on chromosome 22 (2007)
  • Author(s): Kikuchi T, Naruse TK, Onizuka M, Li S, Kimura T, Oka A, Morishima Y, Kulski JK, Ichimiya S, Sato N, Inoko H
  • Journal Title: Immunogenetics 59 Pages: 99-108
  • Peer Reviewed
• [Journal Article] Genes in the HLA region indicative for head and neck squamous cell carcinoma. (2007)
  • Author(s): Reinders J, Rozemuller EH, vander Weide P, Oka A, Slootweg PJ, Inoko H, Tilanus MG
  • Journal Title: Mol Immunol 44 Pages: 848-855
  • Peer Reviewed
• [Journal Article] High-resolution mapping for essential hypertension using microsatellite markers. (2007)
  • Author(s): Yatsu K, Mizuki N, Hirawa N, Oka A, Itoh N, Yamane T, Ogawa M, Shiwa T, Tabara Y, Ohno S, Soma M, Hata A, Nakao K, Ueshima H, Ogihara T, Tomoike H, Miki T, Kimura A, Mano S, Kulski JK, Umemura S, Inoko H
  • Journal Title: Hypertension 49 Pages: 446-452
  • Peer Reviewed
• [Journal Article] Effects of HLA-allele and killer immunoglobulin-like receptor ligand matching on clinical outcome in leukemia patients undergoing transplatation with T-cell-replete marrow from an unrelated donor (2007)
  • Author(s): Morishima Y, Yabe T, Matsuo K, Kashiwase K, Inoko H, Saji H, Yamamoto K, Maruya E, Akatsuka Y, Onizuka M, Sakamaki H, Sao H, Ogawa S, Kato S, Juji T, Sasazuki T, Kodera Y
  • Journal Title: Biol Blood Marrow Transplant 13 Pages: 315-328
  • Peer Reviewed
• [Journal Article] Exclusion of transforming growth factor-beta1 as a candidate gene for myopia in the Japanese (2007)
  • Author(s): Hayashi T, Inoko H, Nishizaki R, Ohno S, Mizuki
  • Journal Title: Jpn J Ophthalmol 51 Pages: 96-99
  • Peer Reviewed
• [Journal Article] Alternative splicing due to an intronic SNP in HMSD generates a novel minor histocompatibility antigen (2007)
  • Author(s): Kawase T, Akatsuka Y, Torikai H, Morishima S, Oka A, Tsujimura A, Miyazaki M, Tsujimura A, Miyamura K, Ogawa S, Inoko H, Morishima Y, Kodera Y, Kuzushima K, Takahashi T
  • Journal Title: Blood 110 Pages: 1055-1063
  • Peer Reviewed
• [Journal Article] The COL1A1 gene and high myopia susceptibility in Japanese. (2007)
  • Author(s): Inamori Y, Ota M, Inoko H, Okada E, Nishizaki R, Shiota T, Mok J, Oka A, Ohno S, Mizuki N
  • Journal Title: Hum Genet 122 Pages: 151-157
  • Peer Reviewed
• [Journal Article] Human leukocyte antigen may predict outcome of primary recurrent spontaneous abortion treated with paternal lymphocyte alloimmunization therapy (2007)
  • Author(s): Kano T, Mori T, Furudono M, Ishikawa H, Watanabe H, Kikkawa E, warita T, Onizuka, M, Takahashi M, Maeda Y, Naruse T, Inoko H, Kimura A
  • Journal Title: Immunol 58 Pages: 383-387
  • Peer Reviewed
• [Journal Article] Lack of association of Toll-like receptor 9 gene polymorphism with Behcet's disease in Japanese patients. (2007)
  • Author(s): Ito A, Ota M, Katsuyama Y, Inoko H, Ohno S, Mizuki N
  • Journal Title: Tissue Antigens 70 Pages: 423-426
  • Peer Reviewed
• [Journal Article] Association of autoimmune disease-related gene polymorphisms with chronic graft-versus-host disease. (2007)
  • Author(s): Shimada M, Onizuka M, Machida S, Suzuki R, Kojima M, Miyamura K, Kodera Y, Inoko H, Ando K
  • Journal Title: Br J Haematol 139 Pages: 458-463
  • Peer Reviewed
• [Journal Article] A single nucleotide polymorphism analysis of the LAMAAl gene in Japanese patients with high myopia. (2007)
  • Author(s): Sasaki S, Ota M, Nishizuka R, Okada E, Mok J, Kimuta T, Oka A, Katsuyama Y, Ohono S, Inoko H, Mizuki N
  • Journal Title: Clinical Opthalmolog 1 Pages: 289-295
  • Peer Reviewed
• [Journal Article] Lack of association with high myopia andthe MYP2 locus in the Japanese population by high resolution analysis on chromosome 18 (2007)
  • Author(s): Yamane T, Mok J, Nishizuka R, Oka A, Nishizaki R, Meguro A, Yonemoto J, Kuiski JK, Ohono S, lnoko H, Mizuki N
  • Journal Title: Clinical Opthalmology 1 Pages: 311-316
  • Peer Reviewed
• [Journal Article] HLA-DPB chain may confer the susceptibility to hepatitis C virus-associated hypertrophic cardiomyopathy. (2007)
  • Author(s): Shichi D, Matsumori A, Naruse KT, Inoko H, Kimura A
  • Journal Title: Int J immunogenetics 35 Pages: 37-43
  • Peer Reviewed
• [Journal Article] Genome-wide association studies define IL23R/IL12RB2 and IL10 as susceptibility loci for Behcet's disease
  • Author(s): Mizuki N, Meguro A, Ota M, Ohno S, Shiota T, Kawagoe T, Ito N, Kera J, Okada E, Yatsu K, Song YW, Lee EB, Kitaichi N, Namba K, Horie Y, Takeno M, Sugita S, Mochizuki M, Bahram S, Ishigatsubo Y, Inoko H
  • Journal Title: Nature Genetics (in press)
  • Peer Reviewed
• [Presentation] 次世代シークエンサーを用いた8桁レベルの完璧なHLA-DNAタイピング (2012)
  • Author(s): 猪子英俊
  • Organizer: 第5回輸血検査研修会
  • Place of Presentation: 兵庫県赤十字血液センター(神戸)(招待講演)
  • Year and Date: 2012-02-12
• [Presentation] ペンギンを通して見る南極を取り巻く生物の多様性保全 (2011)
  • Author(s): 津田とみ、猪子英俊
  • Organizer: 日本DNA多型学会・公開シンポジウム「DNA多型から見た生物の多様性」
  • Place of Presentation: はまぎんホールヴィアマーレ(横浜)(招待講演)
  • Year and Date: 2011-11-30
• [Presentation] 関節リウマチにおけるシステムズ・ゲネティクス・アプローチ～感受性遺伝子座から生物学的経路の推定 (2011)
  • Author(s): 中岡博史、崔泰林、田嶋淳、光永滋樹、猪子英俊、井ノ上逸朗
  • Organizer: 日本人類遺伝学会第56回大会、第11回東アジア人類遺伝学会日本人類遺伝学会第56回大会、第11回東アジア人類遺伝学会
  • Place of Presentation: 幕張メッセ
  • Year and Date: 2011-11-11
• [Presentation] HLAアレルと強く関連する薬剤副作用因子検索のためのHLA領域のシーケンス (2011)
  • Author(s): 細道一善、椎名隆、鈴木進悟、三浦浩美、田平知子、林健志、猪子英俊、井ノ上逸朗
  • Organizer: 日本人類遺伝学会第56回大会、第11回東アジア人類遺伝学会日本人類遺伝学会第56回大会、第11回東アジア人類遺伝学会
  • Place of Presentation: 幕張メッセ
  • Year and Date: 2011-11-10
• [Presentation] 次世代シークエンサーを用いたHLA領域のリシークエンシングによる多型解析 (2011)
  • Author(s): 猪子英俊
  • Organizer: 第9回日本組織適合性学会近畿地方会特別講演
  • Place of Presentation: 大阪
  • Year and Date: 2011-02-05
• [Presentation] HLAと薬物副作用 (2011)
  • Author(s): 猪子英俊
  • Organizer: PGxデータサイエンスコンソーシャム講演
  • Place of Presentation: 東京田辺製薬
  • Year and Date: 2011-02-02
• [Presentation] 次世代シークエンサーを用いたHLAゲノム領域の多様性解析-究極のHLAタイピングとHLAハプロタイプの塩基配列決定- (2011)
  • Author(s): 猪子英俊、鈴木進悟、細道一善、河野あずみ、田中景子、北夕紀、吉川枝里、重成敦子、田中政之、林英樹、井ノ上逸朗、椎名隆
  • Organizer: 第20回日本組織適合性学会大会
  • Place of Presentation: ツインメッセ静岡(招待講演)
• [Presentation] 次世代シークエンサーを用いたHLAクラスI遺伝子タイピング法の開発 (2011)
  • Author(s): 鈴木進悟、吉川枝里、重成敦子、光永滋樹、椎名隆、猪子英俊
  • Organizer: 第20回日本組織適合性学会大会
  • Place of Presentation: ツインメッセ静岡
• [Presentation] 日本人集団におけるHLAと生化学検査値の関連 (2011)
  • Author(s): 奥平裕子、光永滋樹、成田暁、柏背貢一、椎名豊、本間康彦、井ノ上逸朗、猪子英俊
  • Organizer: 第20回日本組織適合性学会大会
  • Place of Presentation: ツインメッセ静岡
• [Presentation] GFPuv遺伝子とTypellS制限酵素を用いた遺伝子発現ベクターの簡便な構築法とその応用 (2011)
  • Author(s): 三浦浩美、佐藤正宏、猪子英俊、大塚正人
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜
• [Presentation] コモンマーモセットMHCクラスI(Caja-G)亜領域のゲノム構造解析 (2011)
  • Author(s): Azumi Kono, 椎名隆、猪子英俊
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜
• [Presentation] HLAI遺伝子における超高解像度DNAタイピング法の開発 (2011)
  • Author(s): 鈴木進悟、尾崎有紀、吉川枝里、重成敦子、光永滋樹、椎名隆、猪子英俊
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜
• [Presentation] HLAII遺伝子における超高解像度DNAタイピング法の開発 (2011)
  • Author(s): 尾崎有紀、椎名隆、鈴木進悟、、吉川枝里、重成敦子、岡晃、光永滋樹、猪子英俊
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜
• [Presentation] エクソーム解析による関節リウマチ感受性遺伝子の探索 (2011)
  • Author(s): 奥平裕子、光永滋樹、國井七絵、細道一善、田中政之、林英樹、河田寿子、鈴木康夫、佐藤慎二、本間康彦、井ノ上逸朗、猪子英俊、
  • Organizer: 第34回日本分子生物学会年会
  • Place of Presentation: パシフィコ横浜
• [Presentation] HLAの多型と疾患感受性 (2010)
  • Author(s): 猪子英俊
  • Organizer: 日本癌病態治療研究会学術講演会
  • Place of Presentation: 東京都市センターホテル
  • Year and Date: 2010-11-04
• [Presentation] 摂食障害のゲノム解析GWAS(Genome-Wide Association Studies)と今後のWhole Genome Sequencing (2010)
  • Author(s): 猪子英俊
  • Organizer: 摂食障害遺伝子研究協力者会議
  • Place of Presentation: 東京
  • Year and Date: 2010-10-15
• [Presentation] 健康と遺伝子 (2010)
  • Author(s): 猪子英俊
  • Organizer: ワールドハートデイ神戸
  • Place of Presentation: 神戸学院大学
  • Year and Date: 2010-09-26
• [Presentation] 漢方医学教育養成のための神奈川県4大学連携型によるシステムの構築 (2010)
  • Author(s): 猪子英俊
  • Organizer: 第2回福島県立大東洋医学研究会
  • Place of Presentation: 福島県立医科大学
  • Year and Date: 2010-09-10
• [Presentation] 身体はゲノムの単なる乗り物か? (2010)
  • Author(s): 猪子英俊
  • Organizer: 第67回日本臨床検査医学会関東甲信越支部例会/第21回神奈川県臨床検査医学会大会
  • Place of Presentation: 横浜
  • Year and Date: 2010-05-29
• [Presentation] ゲノムワイドな相関解析によるありふれた疾患の遺伝子の同定とゲノム創薬 (2010)
  • Author(s): 猪子英俊
  • Organizer: 第79回神奈川腎研究会
  • Place of Presentation: 北里大学
  • Year and Date: 2010-05-15
• [Presentation] Genome-wide association studies using microsatellteis identifies a new psoriaisi susceptibility locus on chromosome 6 (2010)
  • Author(s): Oka A, Hayashi H, Ozawa A, Beck S, Inoko H
  • Organizer: The 3rd Gottingen Workshop on Immunology and Immunogenetics
  • Place of Presentation: German Primate Centerゲッティンゲン(ドイツ)
• [Presentation] Genome-wide association studies define IL23R/IL12RB2 and IL10 as susceptibility loci for Behcet's Disease (2010)
  • Author(s): Inoko H
  • Organizer: The 3rd Gottingen Workshop on Immunology and Immunogenetics
  • Place of Presentation: German Primate Center,ゲッティンゲン(ドイツ)
• [Presentation] Genome-wide association studies using microsatellteis identifies a new psoriaisi susceptibility locus on chromosome 6 (2010)
  • Author(s): Oka A, Hayashi H, Ozawa A, Beck S, Inoko H
  • Organizer: HGM(Human Genome Meeting) Workshop
  • Place of Presentation: Le Corum,モンペリエ(フランス)
• [Presentation] 予防医学におけるHLAと疾患発症機構の因果関係 (2009)
  • Author(s): 猪子英俊
  • Organizer: 第42回中国四国医学検査学会
  • Place of Presentation: 高松
  • Year and Date: 2009-10-31
• [Presentation] Identification of NFKBIL1 as a susceptible locus of rheumatoid arthritis by genome-wide association using microsatellites and its functional analysis in steoclastogenesis. (2009)
  • Author(s): Inoko H
  • Organizer: Simposium "Pathogenesis and epidemiology of Intgraocular inflammation" The 10th Congress of International Ocular Inflammation Society
  • Place of Presentation: チェコ(プラハ)
  • Year and Date: 2009-06-02
• [Presentation] 漢方医学教員養成のための4大学連携によるシステムの構築 (2009)
  • Author(s): 猪子英俊
  • Organizer: 漢方メディカルシンポジウム2009
  • Place of Presentation: 東京
  • Year and Date: 2009-02-07
• [Presentation] HLAの多型性とその生物学的意義 (2009)
  • Author(s): 猪子英俊
  • Organizer: 第1回移植免疫を学ぶ会
  • Place of Presentation: 名古屋
  • Year and Date: 2009-01-30
• [Presentation] ゲノム医学と生活習慣病関連遺伝子の探索 (2009)
  • Author(s): 猪子英俊
  • Organizer: 第15回湘南医学研究会
  • Place of Presentation: 武田クリニック
  • Year and Date: 2009-01-16
• [Presentation] Identification of NFKBIL1 as a susceptible locus of rheumatoid arthritis by genome-wide association using microsatellites and its functional analysis in steoclastogenesis. Simposium "Pathogenesis and epidemiology of Intgraocular inflammation" (2009)
  • Author(s): Inoko H
  • Organizer: The 10th Congress of International Ocular Inflammation Society
  • Place of Presentation: プラハ(チェコ共和国)
• [Presentation] HLA領域の遺伝子構造解析と疾患関連解析 (2009)
  • Author(s): 猪子英俊、細道一善、椎名隆、井ノ上逸朗
  • Organizer: 第18回日本組織適合性学会
  • Place of Presentation: 名古屋
• [Presentation] HLA領域のパーソナルゲノム解析法の開発 (2009)
  • Author(s): 細道一善、猪子英俊、河田寿子、井ノ上逸朗、椎名隆
  • Organizer: 第18回日本組織適合性学会
  • Place of Presentation: 名古屋
• [Presentation] プラスチック基板上での等温増幅反応によるHLAタイピング (2009)
  • Author(s): 奥平裕子、光永滋樹、山口香織、吉川枝里、岡晃、猪子英俊
  • Organizer: 第18回日本組織適合性学会
  • Place of Presentation: 名古屋
• [Presentation] Target transgenesis through pronuclear injection. (2009)
  • Author(s): 大塚正人、三浦浩美、荻原早苗、木村穣、猪子英俊
  • Organizer: 第32回日本分子生物学会
  • Place of Presentation: 横浜
• [Presentation] Validation of artificial miRNA expression vectors for generation of knockdown mice. (2009)
  • Author(s): 三浦浩美、猪子英俊、木村穣、大塚正人
  • Organizer: 第32回日本分子生物学会
  • Place of Presentation: 横浜
• [Presentation] MHC研究の歴史～過去、現在そして未来 (2009)
  • Author(s): 猪子英俊
  • Organizer: 第7回最先端遺伝育種セミナー講演
  • Place of Presentation: 筑波
• [Presentation] HLA多型の魅力-疾患解析のモデル領域 (2009)
  • Author(s): 猪子英俊
  • Organizer: 第54回日本人類遺伝学会招待講演
  • Place of Presentation: 高輪
• [Presentation] Loop-Mediated Isothermal Amplification法によるambigulty解決の可能性 (2008)
  • Author(s): 清水佐良子, 光永滋樹, 吉川枝里, 岡晃, 猪子英
  • Organizer: 第17回日本組織適合性学会大会
  • Place of Presentation: 大阪国際会議場
  • Year and Date: 2008-09-21
• [Presentation] SLAハプロタイプ固定近交系デュロックブタにおける抗体産生 (2008)
  • Author(s): 安藤麻子, 今枝紀明, 吉岡豪, 岡本宏明, 猪子英俊, その, 他
  • Organizer: 第17回日本組織適合性学会大会
  • Place of Presentation: 大阪国際会議場
  • Year and Date: 2008-09-21
• [Presentation] 日本人サルコイドーシスにおけるBTNL 2 遺伝子多型の解析 (2008)
  • Author(s): 目黒明, 石原麻美, 勝山善彦, 南田研一, 蕪城俊克, 猪子英俊, その, 他
  • Organizer: 第17回日本組織適合性学会大会
  • Place of Presentation: 大阪国際会議場
  • Year and Date: 2008-09-20
• [Presentation] 生活習慣病などの難病の発症に関わる遺伝子群による罹患予測、及び機能解析による創薬の標的の絞り込み (2008)
  • Author(s): 猪子英俊
  • Organizer: 2008年度健康食品管理士会近畿支部講演会
  • Place of Presentation: 神戸学院大学ポートアイランドキャンパス
  • Year and Date: 2008-05-25
• [Presentation] Comparative genome analysis of the MHC regions in primate species (2008)
  • Author(s): Shiina T, Inoko H
  • Organizer: Sattelite Sympojium of the 22nd EFI meeting "Non-human Primate Immunogenetics"
  • Place of Presentation: トゥールーズ(フランス)
• [Presentation] ほ乳類の主要組織適合遺伝子複合体(MHC)領域における比較ゲノム解析 (2008)
  • Author(s): 椎名隆, 細道一善, 北夕紀, 井関直政, 猪子英俊, その, 他
  • Organizer: 第31回日本分子生物学会年会、第81回日本生化学大会合同大会
  • Place of Presentation: 神戸ポートアイランド
• [Presentation] mtDNAを用いた軟骨魚類の網羅的分子進化系統樹解析 (2008)
  • Author(s): 河野あづみ, 椎名隆, 田中彰, 猪子英俊
  • Organizer: 日本進化学会2008年大会
  • Place of Presentation: 東京大学駒場キャンパス
• [Presentation] オキゴンドウMHC領域のゲノム配列決定と比較ゲノム解析 (2008)
  • Author(s): 渡辺舞, 細道一善, 野口英樹, 黒木陽子, 猪子英俊, その, 他
  • Organizer: 第31回日本分子生物学会年会、第81回日本生化学大会合同大会
  • Place of Presentation: 神戸ポートアイランド
• [Presentation] ニワトリMHC領域におけるゲノム多様性 (2008)
  • Author(s): 細道一善, 鈴木進悟, Ronald M Goto, 西堀正英, 猪子英俊, その, 他
  • Organizer: 第31回日本分子生物学会年会、第81回日本生化学大会合同大会
  • Place of Presentation: 神戸ポートアイランド
• [Presentation] カニクイザル3集団における主要組織適合遺伝子複合体クラスI遺伝子(Ma fa-A)の多型解析とHLA-Aとの比較 (2008)
  • Author(s): 北夕紀, 椎名隆, 小原栄, 小笠原一誠, 猪子英俊, その, 他
  • Organizer: 第31回日本分子生物学会年会、第81回日本生化学大会合同大会
  • Place of Presentation: 神戸ポートアイランド
• [Presentation] リウマチモデルカニクイザル作製のための新規マーカーの探索 (2008)
  • Author(s): 小原栄, 北夕紀, 賓来直人, 葛西勇人, 鵜藤雅裕, 猪子英俊, その, 他
  • Organizer: 第31回日本分子生物学会年会、第81回日本生化学大会合同大会
  • Place of Presentation: 神戸ポートアイランド
• [Presentation] ベーチェット病感受性ゲノム領域に位置するTRIM遺伝子群のSNP関連解析 (2008)
  • Author(s): 倉田里穂, 斉藤卓磨, 細道一善, 目黒明, 猪子英俊, その, 他
  • Organizer: 2008分子生物学会
  • Place of Presentation: 神戸ボートアイランド
• [Presentation] 鳥類細胞を用いた環境汚染物質の比較免疫学的研究 (2008)
  • Author(s): 井関直政, 椎名隆, 割田貴之, 木村譲, 猪子英俊, その, 他
  • Organizer: 2008分子生物学会
  • Place of Presentation: 神戸ボートアイランド
• [Presentation] 医療の中で活用される遺伝子解析 (2008)
  • Author(s): 猪子英俊
  • Organizer: 東洋医学セミナー 市民公開講座
  • Place of Presentation: 小田急ホテルセンチュリー相模大野
• [Presentation] RMCE法を介入して最終的にmarker-freeな遺伝子導入を行う新手法の開発 (2007)
  • Author(s): 大塚 正人, 荻原 早苗, 今井 賢治, 猪子 英俊
  • Organizer: 第30回日本分子生物学会・第80回日本生化学会 合同大会(Biochemistry and Molecular Biology)
  • Place of Presentation: 横浜(パシフィコ横浜)
  • Year and Date: 2007-12-11
• [Presentation] パーキンソン病のゲノムワイド関連解析 (2007)
  • Author(s): 戸田 達史, 佐竹 渉, 水田 依久子, 山本 光利, 猪子 英俊, 服部 信孝, 村田 美穂
  • Organizer: 第30回日本分子生物学会・第80回日本生化学会 合同大会(Biochemistry and Molecular Biology)
  • Place of Presentation: 横浜(パシフィコ横浜)
  • Year and Date: 2007-12-11
• [Presentation] マイクロサテライトマーカーを用いたゲノムワイド関連解析により同定された心筋梗塞感受性遺伝子座MI-1の解析 (2007)
  • Author(s): 日野原 邦彦, 安波 道郎, 柴田 宏樹, 高橋 弓子, 高橋 めぐみ, 有村 卓朗, 宝田 茂, 笹岡 大史, 山本 健, 猪子 英俊, 山田 芳司, 和泉 徹, 中島 敏昌, 木村 影方
  • Organizer: 第30回日本分子生物学会・第80回日本生化学会 合同大会(Biochemistry and Molecular Biology)
  • Place of Presentation: 横浜(パシフィコ横浜)
  • Year and Date: 2007-12-11
• [Presentation] ヒト生活習慣病の発症に関わる遺伝子の探索とその意義 (2007)
  • Author(s): 猪子 英俊
  • Organizer: 第58回日本染色体学会、第17回染色体コロキウム2007年合同大会ワークショップ
  • Place of Presentation: 葉山
  • Year and Date: 2007-11-28
• [Presentation] 3万個のマイクロサテライト多型を用いたゲノムワイド関連解析 (2007)
  • Author(s): 猪子 英俊
  • Organizer: 第52回日本人類遺伝学会シンポジウム
  • Place of Presentation: 東京
  • Year and Date: 2007-09-13
• [Presentation] HLA-DP遺伝子はC型肝炎ウィルス陽性肥大型心筋症と関連する (2007)
  • Author(s): 志知 大輔, 松森 昭, 高橋 めぐみ, 成瀬 妙子, 猪子 英俊, 木村 影方
  • Organizer: 第16回日本組織適合性学会大会
  • Place of Presentation: 京都
  • Year and Date: 2007-09-11
• [Presentation] 主要組織適合遺伝子複合体(MHC)領域におけるニワトリを含む脊椎動物の間の比較ゲノム解析 (2007)
  • Author(s): 椎名 隆, 細道 一善, 北夕 紀, 渡辺 舞, 河野 あつみ, 倉田 里穂, 柴原 悠, 佐藤 和広, 金藤 聡美, 猪子 英俊
  • Organizer: 日本比較免疫学会第19回学術集会シンポジウム
  • Place of Presentation: 静岡
  • Year and Date: 2007-08-22
• [Presentation] Genome-wide scan of genes for Multi-Factorial Diseases such as common diseases by association analysis using microsatellites (2007)
  • Author(s): 猪子 英俊
  • Organizer: 第30回心筋代謝研究会
  • Place of Presentation: 京都
  • Year and Date: 2007-07-14
• [Presentation] シックハウス症候群におけるNeuropathy Target Esterase(NTE)酵素活性および遺伝子多型 (2007)
  • Author(s): 松坂 恭成, 津田 道雄, 大久保 朋一, 菊池 イアーラ幸江, 青山 美子, 角田 和彦, 坂部 貢, 猪子 英俊, 石川 哲, 木村 穣
  • Organizer: 第16回日本臨床環境医学会総会
  • Place of Presentation: 東京
  • Year and Date: 2007-07-07
• [Presentation] Comparative genome analysis of the MHC regions in vertebrate species (2007)
  • Author(s): Shiina T, Inoko H
  • Organizer: Goettingen Workshop on Immunogenetics
  • Place of Presentation: German Primate Center,ゲッティンゲン(ドイツ)
• [Remarks]
  • URL: http://inoko.med.u-tokai.ac.jp/
• [Remarks]
  • URL: http://www.jbirc.aist.go.jp/gdbs
• [Remarks]
  • URL: http://inoko.med.u-tokai.ac.jp/
• [Remarks]
  • URL: http://www.jbirc.aist.go.jp/gdbs
• [Remarks]
  • URL: http://inoko.med.u-tokai.ac.jp/index.htm
• [Remarks] 1)3万個のマイクロサテライトの位置、PCRプライマー、多型頻度などの情報に関するデータベース
  • URL: http://www.jbirc.aist.go.jp/gdbs
• [Remarks] 2)研究室のweb site
  • URL: http://mls.med.u-tokai.ac.jp/
• [Patent(Industrial Property Rights)] 猪子英俊、良原栄策、光永滋樹 (2010)
  • Inventor(s): 東海大学
  • Filing Date: 2010-02-26
• [Patent(Industrial Property Rights)] (2009)
  • Inventor(s): 猪子英俊、良原栄策、光永滋樹
  • Industrial Property Rights Holder: 東海大学
  • Filing Date: 2009-06-16
• [Patent(Industrial Property Rights)] 基板上での等温増幅反応による標的塩基配列の補足及び検出方法 (2007)
  • Inventor(s): 光永滋樹、清水佐良子、猪子英俊
  • Industrial Property Rights Holder: 東海大学、ジェノダイブファーマ
  • Filing Date: 2007-10-31