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The genome-wide study on the regulation of muscle differentiation in fish

Research Project

Project/Area Number 19108003
Research Category

Grant-in-Aid for Scientific Research (S)

Allocation TypeSingle-year Grants
Research Field Fisheries chemistry
Research InstitutionThe University of Tokyo

Principal Investigator

WATABE Shugo  東京大学, 大学院・農学生命科学研究科, 教授 (40111489)

Co-Investigator(Kenkyū-buntansha) KINOSHITA Shigeharu  東京大学, 大学院・農学生命科学研究科, 助教 (40401179)
OCHIAI YOSHIHIRO  東京大学, 大学院・農学生命科学研究科, 准教授 (50160891)
KANEKO TOYOJI  東京大学, 大学院・農学生命科学研究科, 教授 (70221190)
Co-Investigator(Renkei-kenkyūsha) OCHIAI Yoshihiro  東京大学, 大学院・農学生命科学研究科, 准教授 (50160891)
KANEKO Toyoji  東京大学, 大学院・農学生命科学研究科, 教授 (70221190)
Project Period (FY) 2007 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥103,350,000 (Direct Cost: ¥79,500,000、Indirect Cost: ¥23,850,000)
Fiscal Year 2011: ¥15,080,000 (Direct Cost: ¥11,600,000、Indirect Cost: ¥3,480,000)
Fiscal Year 2010: ¥15,080,000 (Direct Cost: ¥11,600,000、Indirect Cost: ¥3,480,000)
Fiscal Year 2009: ¥15,080,000 (Direct Cost: ¥11,600,000、Indirect Cost: ¥3,480,000)
Fiscal Year 2008: ¥25,090,000 (Direct Cost: ¥19,300,000、Indirect Cost: ¥5,790,000)
Fiscal Year 2007: ¥33,020,000 (Direct Cost: ¥25,400,000、Indirect Cost: ¥7,620,000)
Keywords水産学 / 魚類 / ゲノム / 発生・分化 / 筋肉 / ミオシン / 発生分化 / ミオシン重鎖 / 転写制御 / トラフグ / 小型魚類 / 発生 / 分化 / 発生・文化 / 遺伝子発現解析 / レポーターアッセイ
Research Abstract

This study focused on myosin heavy chain gene(MYH), which defines muscle properties. We showed that diverse expression of MYHs is closely related to structures and functions of the muscle in fish, revealing a part of transcriptional network involved in the regulation of MYH expression. These findings are expected to contribute to fisheries industry by, for example, the improvement of meat quality and the establishment of fast growth fish strains, based on the molecular mechanisms involved in muscle differentiation and growth.

Report

(7 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report   Self-evaluation Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (98 results)

All 2012 2011 2010 2009 2008 2007 Other

All Journal Article (27 results) (of which Peer Reviewed: 27 results) Presentation (65 results) Book (4 results) Remarks (2 results)

  • [Journal Article] The occurrence of two types of fast skeletal myosin heavy chains from abdominal muscle of kuruma shrimp Marsupenaeus japonicus and their different tissue distribution2012

    • Author(s)
      Koyama H, Akolkar DB, Shiokai T, Nakaya M, Piyapattanakorn S, Watabe S
    • Journal Title

      The Journal of Experimental Biology

      Volume: 215 Issue: 1 Pages: 14-21

    • DOI

      10.1242/jeb.058206

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Multiple cis-elements in the 5'-flanking region of embryonic/larval fast-type of the myosin heavy chain gene of torafugu2011

    • Author(s)
      Asaduzzaman Md, Kinoshita S, Watabe S
    • Journal Title

      Gene

      Volume: 489 Pages: 41-54

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Species-specific expression variation of fish MYH142011

    • Author(s)
      Kinoshita S, Bhuyian SS, Ceyhun SB, Asaduzzaman Md, Asakawa S, Watabe S
    • Journal Title

      Fish. Sci.

      Volume: 77 Pages: 847-853

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] A 5'-flanking region of embryonic-type myosin heavy chain gene, MYH_<M743-2>, from torafugu(Takifugu rubripes) regulates developmental muscle-specific expression2011

    • Author(s)
      Yasmin L, Kinoshita S, Asaduzzaman Md, Akolkar DB, Ikeda D, Ono Y, Watabe S
    • Journal Title

      Comp. Biochem. Physiol. D

      Volume: 6 Pages: 76-81

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Multiple cis-elements in the 5'-flanking region of embryonic/larval fast-type of the myosin heavy chain gene of torafugu, myh_<m743-2>, function in the regulation of its expression2011

    • Author(s)
      Asaduzzaman Md, Kinoshita S, Watabe S
    • Journal Title

      Gene

      Volume: 489 Issue: 1 Pages: 41-54

    • DOI

      10.1016/j.gene.2011.08.005

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Species-specific expression variation of fish MYH14, an ancient vertebrate myosin heavy chain gene orthologue2011

    • Author(s)
      Kinoshita S, Bhuyian SS, Ceyhun SB, Asaduzzaman Md, Asakawa S, Watabe S
    • Journal Title

      Fisheries Science

      Volume: 77 Issue: 5 Pages: 847-853

    • DOI

      10.1007/s12562-011-0375-2

    • NAID

      10029457853

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A5'-flanking region of embryonic-type myosin heavy chain gene, MYH_M743-2, from torafugu(Takifugu rubripes)regulates developmental muscle-specific expression2011

    • Author(s)
      Yasmin L, Kinoshita S, Asaduzzaman M, Akolkar DB, Ikeda D, Ono Y, Watabe S
    • Journal Title

      Comp.Biochem.Physiol.D

      Volume: 6 Pages: 76-81

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Three embryonic myosin heavy chain genes encoding different motor domain structures from common carp show distinct expression patterns in cranial muscles2010

    • Author(s)
      Ikeda D, Nihei Y, Ono Y, Watabe S
    • Journal Title

      Mar. Genom

      Volume: 3 Pages: 1-9

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Early development of medaka Oryzias latipes muscles as revealed by transgenic approaches using embryonic and larval types of myosin heavy chain genes2010

    • Author(s)
      Ono Y, Kinoshtia S, Ikeda D, Watabe S
    • Journal Title

      Dev. Dyn

      Volume: 239 Pages: 1807-1817

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Fibre-type-specific expression patterns of myosin heavy chain genes in adult torafugu Takifugu rubripes muscles2010

    • Author(s)
      Akolkar DB, Yamaguchi H, Kinoshita S, Yasmin L, Ono Y, Ikeda D, Nakaya M, Erdogan O, Watabe S
    • Journal Title

      J. Exp. Biol

      Volume: 213 Pages: 137-145

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Fibre-type-specific expression patterns of myosin heavy chain genes in adult torafugu Takifugu rubripes muscles2010

    • Author(s)
      Akolkar D. B, Kinoshita S., Yasmin L., Ono Y., Ikeda D., Yamaguchi H., Nakaya M., Erdogan O., Watabe S.
    • Journal Title

      J.Exp.Biol. 213

      Pages: 137-145

    • Related Report
      2009 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Three embryonic myosin heavy chain genes encoding different motor domain structures from commom carp show distinct expression patterns in cranial muscles2010

    • Author(s)
      Daisuke Ikeda, Yoshiaki Nihei, Yosuke Ono, Shugo Watabe
    • Journal Title

      Marine Genomics (In press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Early development of medaka Oryzias latipes muscles as revealed by transgenic approaches using embryonic and larval types of myosin heavy chain genes2010

    • Author(s)
      Yosuke Ono, Shigeharu Kinoshtia, Daisuke Ikeda, Shugo Watabe
    • Journal Title

      Developmental Dynamics (In press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fibre-type-specific expression patterns of myosin heavy chain genes inadult torafugu Takifugu rubripes muscles2010

    • Author(s)
      Dadasahab B Akolkar, Hiroko Yamaguchi, Shigeharu Kinoshita, Lubna Yasmin, Yosuke Ono, Daisuke Ikeda, Misako Nakaya, Orhan Erdogan, Shugo Watabe
    • Journal Title

      Journal of Experimental Biology 213

      Pages: 137-145

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Structural differences in the motor domain of temperature-associated myosin heavy chain isoforms from grass carp fast skeletal muscle2009

    • Author(s)
      Yan Tao, Sun-Yong Wang, Chun-Shi Liang, Hideto Fukushima, Shugo Watabe
    • Journal Title

      Comparative Biochemistry and Physiology Parb B 154

      Pages: 248-254

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Myosin heavy chain genes expressed in juvenile and adult silver carp Hypopthalmichthys molitrix : novel fast-type myosin heavy chain genes of silver carp2009

    • Author(s)
      Hideto Fukushima, Daisuke Ikeda, Yan Tao, Shugo Watabe
    • Journal Title

      Gene 432

      Pages: 102-111

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Myocyte enhancer factor 2 regulates expression of medaka Oryzias latipes fast skeletal myosin heavy chain genes in a temperature-dependent manner2008

    • Author(s)
      Liang CS, Ikeda D, Kinoshita S, Shimizu A, Sasaki T, Asakawa S, Shimizu N, Watabe S
    • Journal Title

      Gene

      Volume: 407 Pages: 42-53

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] The occurrence of tissue-specific twitchin isoforms in the mussel Mytilus galloprovincialis2008

    • Author(s)
      Miho Kusaka, Daisuke Ikeda, Daisuke Funabara, David J. Hartshorne, and Shugo Watabe
    • Journal Title

      Fisheries Science 74

      Pages: 677-686

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] cDNA cloning and complete primary structures of myosin heavy chains from brushtooth lizardfish (Saurida undosquamis) and wanieso lizardfish (S. wanieso) fast skeletal muscles2008

    • Author(s)
      Mohammed Anwar Hossain, Daisuke Ikeda, Akira Nomura, Hideto Fukushima, and Shugo Watabe
    • Journal Title

      Fisheries Science 74

      Pages: 921-934

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] cDNA cloning and characterization of temperature-acclimation-associated light meromyosins from grass carp fast skeletal muscle2008

    • Author(s)
      S, Y.Wang, Y.Tao, C.S.Liang, H.Fukushima, and S.Watabe
    • Journal Title

      Comparative Biochemistry and Physiology Part B:Biochemistry and Molecular Biology 149

      Pages: 378-387

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Myocyte enhancer factor 2 regulates expression of medaka Oryzias latipes fast skeletal myosin heavy chain genes in a temperature-dependent manner2008

    • Author(s)
      C.S.Liang, D, Ikeda, S.Kinoshita, A.Shimizu, T, Sasaki, S.Asakawa, N.Shimizuand S.Watabe
    • Journal Title

      Gene 407

      Pages: 42-53

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Divergent evolution of the myosin heavy chain gene family in fish and tetrapods ; evidence from comparative genomic analysis2007

    • Author(s)
      Ikeda D, Ono Y, Snell P, Edwards YJK, Elgar G, Watabe S
    • Journal Title

      Physiol Genom

      Volume: 32 Pages: 1-15

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Fast skeletal muscle myosin heavy chain gene cluster of medaka Oryzias latipes enrolled in temperature adaptation2007

    • Author(s)
      Liang CS, Kobiyama A, Shimizu A, Sasaki T, Asakawa S, Shimizu N, Watabe S
    • Journal Title

      Physiol. Genom

      Volume: 29 Pages: 201-214

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Divergent evolution of the myosin heavy chain gene family in fish and tetrapods;evidence from comparative genomic analysis2007

    • Author(s)
      D.Ikeda, Y.Ono, P.Snell, Y.J. K.Edwards, G.Elgar, and S.Watabe
    • Journal Title

      Physiological Genomics 32

      Pages: 1-15

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Unphosporylated twitchin forms a complex with actin and myosin that may contribute to tension maintenance in catch2007

    • Author(s)
      D. runiaoara,C. riamamoto,K. Yamamoto, A. Inoue, M. Ueda, R. Osawa, S. Kanoh, D.J. Hartshorne, S. Suzuki, and S.Wat〓
    • Journal Title

      Jouranl of Experimental Biology 210

      Pages: 4399-4410

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Fast skeletal muscle myosin heavy chain gene cluster of medaka Oryzias latips enrolled in temperature adaptation2007

    • Author(s)
      C.S.Liang, A. Kobiyama, A. Shimizu, T. Sasaki, S. Asakawa, N. Shimizu, and S. Watabe
    • Journal Title

      Physiological Genomics 29

      Pages: 201-214

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Early development of medaka Oryzias latipes muscles as revealed by transgenic approaches using embryonic and larval types of myosin heavy chain genes

    • Author(s)
      Ono Y., Kinoshita S., Ikeda D., Watabe S.
    • Journal Title

      Dev.Dyn. (in press)

    • Related Report
      2009 Self-evaluation Report
    • Peer Reviewed
  • [Presentation] 魚類の遅筋・心筋型ミオシン重鎖遺伝子の組織特異的発現を制御するプロモーターの活性について2012

    • Author(s)
      木下滋晴・Ceyhun SB・Bhuyian SS・Asaduzzaman Md・浅川修一・渡部終五
    • Organizer
      平成24年度日本水産学会春季大会
    • Place of Presentation
      東京海洋大学(東京)
    • Year and Date
      2012-03-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] The promoter of torafugu myosin heavy chain gene MYH_<m86-2> harbors fast muscle-specific repression elements to govern slow muscle-specific expression2012

    • Author(s)
      Asaduzzaman Md, Kinoshita S, Bhuyian SS, Asakawa S, Watabe S
    • Organizer
      平成24年度日本水産学会春季大会
    • Place of Presentation
      東京海洋大学(東京)
    • Year and Date
      2012-03-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] Function of intronic miRNA of myosin heavy chain gene, MYH14, in fish muscle formation2012

    • Author(s)
      Bhuyian SS, Kinoshita S, Ceyhun SB, Asaduzzaman Md, Asakawa S, Watabe S
    • Organizer
      平成24年度日本水産学会春季大会
    • Place of Presentation
      東京海洋大学(東京)
    • Year and Date
      2012-03-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] Temperature plasticity of fish skeletal muscles with a special emphasis on myosin heavy chains2011

    • Author(s)
      Watabe S
    • Organizer
      The International Symposium on Muscle Biochemistry
    • Place of Presentation
      東京
    • Year and Date
      2011-10-29
    • Related Report
      2011 Final Research Report
  • [Presentation] Temperature plasticity of fish skeletal muscles with a special emphasis on myosin heavy chains2011

    • Author(s)
      Watabe S
    • Organizer
      The International Symposium on Muscle Biochemistry
    • Place of Presentation
      東京大学(東京)(招待講演)
    • Year and Date
      2011-10-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] Regulation of myosin heavy chain gene expression and muscle development in teleosts2011

    • Author(s)
      Kinoshita S, Bhuyian SS, Ceyhun SB, Asaduzzaman Md, Asakawa S, Watabe S
    • Organizer
      The International Symposium on Muscle Biochemistry
    • Place of Presentation
      東京大学(東京)(招待講演)
    • Year and Date
      2011-10-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] The expression patterns and tissue distribution of two types of myosin heavy chains from abdominal muscles of three shrimp species2011

    • Author(s)
      Koyama H, Akolkar DB, Shiokai T, Nakaya M, Piyapattanakorn S, Watabe S
    • Organizer
      The International Symposium on Muscle Biochemistry
    • Place of Presentation
      東京大学(東京)
    • Year and Date
      2011-10-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] The expression of embryonic/larval fast-type of the myosin heavy chain gene, MYH_<M743-2>, of torafugu is transcriptionally regulated by multiple cis-elements in its 5'-flanking region2011

    • Author(s)
      Asaduzzaman Md, Kinoshita S, Bhuyian SS, Asakawa s, Watabe S
    • Organizer
      The International Symposium on Muscle Biochemistry
    • Place of Presentation
      東京大学(東京)
    • Year and Date
      2011-10-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] Different expression patterns of the myosin heavy chain gene, MYH14, including its intronic miRNA among a few model fish species2011

    • Author(s)
      Bhuyian SS, Kinoshita S, Ceyhun SB, Asaduzzaman Md, Asakawa S, Watabe S
    • Organizer
      The International Symposium on Muscle Biochemistry
    • Place of Presentation
      東京大学(東京)
    • Year and Date
      2011-10-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] Expression analysis of fast-type myosin heavy chain genes in bluefin tuna2011

    • Author(s)
      Onishi A, Koyama H, Kinoshita S, Ushio H, Watabe S
    • Organizer
      The International Symposium on Muscle Biochemistry
    • Place of Presentation
      東京大学(東京)
    • Year and Date
      2011-10-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] Biochemical properties of fast skeletal muscle myosin and skin and dorsal muscle collagens of torafugu Takifugu rubripes2011

    • Author(s)
      Yamaguchi H, Nakaya M, Mochizuki T, Watabe S
    • Organizer
      The International Symposium on Muscle Biochemistry
    • Place of Presentation
      東京大学(東京)
    • Year and Date
      2011-10-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] 遅筋/心筋型魚類ミオシン重鎖遺伝子のプロモーター活性に及ぼすsonic hedgehogシグナル経路の影響2011

    • Author(s)
      木下滋晴・Ceyhun SB・Bhuyian SS・Asaduzzaman Md・浅川修一・渡部終五
    • Organizer
      平成23年度日本水産学会秋季大会
    • Place of Presentation
      長崎大学(長崎)
    • Year and Date
      2011-09-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] Differential expression of the myosin heavy chain gene, MYH14, and its intronic miRNA among fish species2011

    • Author(s)
      Bhuyian SS, Kinoshita S, Ceyhun SB, Asaduzzaman Md, Asakawa S, Watabe S
    • Organizer
      平成23年度日本水産学会秋季大会
    • Place of Presentation
      長崎大学(長崎)
    • Year and Date
      2011-09-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] Fish muscle growth is closely associated with expression of multiple myosin heavy chain genesThe Company of Biologists Workshops2011

    • Author(s)
      Watabe S
    • Organizer
      The Company of Biologists Workshops
    • Place of Presentation
      West Sussex, UK
    • Year and Date
      2011-06-28
    • Related Report
      2011 Final Research Report
  • [Presentation] Fish muscle growth is closely associated with expression of multiple myosin heavy chain genes2011

    • Author(s)
      Watabe S
    • Organizer
      The Company of Biologists Workshops
    • Place of Presentation
      West Sussex, UK(招待講演)
    • Year and Date
      2011-06-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] Zebrafish MYH14, an orthologue of the torafugu slow/cardiac-type myosin heavy chain gene, MYH_M5, is expressed in zebrafish fast musle2011

    • Author(s)
      Bhuyian SS, Kinoshita S, Ceyhun S, Md.Asaduzzaman, Asakawa S, Watabe S
    • Organizer
      日本水産学会春季大会
    • Place of Presentation
      東京海洋大学(東京)
    • Year and Date
      2011-03-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] SRF-binding elements in the 5'-flanking region of embryonic/larval fast-type of the myosin heavy chain gene of torafugu, MYH_M743-2, function in the regulation of its expression2011

    • Author(s)
      Md.Asaduzzaman, Kinoshita S, Bhuyian SS, Asakawa S, Watabe S
    • Organizer
      日本水産学会春季大会
    • Place of Presentation
      東京海洋大学(東京)
    • Year and Date
      2011-03-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] Molecular biological approaches on fish muscle formation and growth based on the torafugu genome database2011

    • Author(s)
      Kinoshita S, Asakawa S, Watabe S
    • Organizer
      2^<nd> JAMBIO forum
    • Place of Presentation
      筑波大学下田臨海実験センター(静岡)(招待講演)
    • Year and Date
      2011-01-21
    • Related Report
      2010 Annual Research Report
  • [Presentation] 魚類の筋形成過程で働くミオシン重鎖遺伝子のプロモーター解析2011

    • Author(s)
      木下滋晴・Md.Asaduzzaman・浅川修一・渡部終五
    • Organizer
      2011年生体運動研究合同班会議
    • Place of Presentation
      大阪市立大学(大阪)
    • Year and Date
      2011-01-07
    • Related Report
      2010 Annual Research Report
  • [Presentation] Multiple cis-elements in the 5'-flanking region of embryonic/larval fast-type of the myosin heavy chain gene of torafugu, myh_<m743-2>, function in the regulation of its expression2011

    • Author(s)
      Asaduzzaman Md, Kinoshita S, Watabe S
    • Organizer
      The Company of Biologists Workshops
    • Place of Presentation
      West Sussex, UK
    • Related Report
      2011 Annual Research Report
  • [Presentation] Transcriptional regulation of the torafugu myosin heavy chain gene, MYH^<M5>, during the slow muscle development2011

    • Author(s)
      Kinoshita S, Ceyhun SB, Bhuyian SS, Asaduzzaman Md, Asakawa S, Watabe S
    • Organizer
      The Company of Biologists Workshops
    • Place of Presentation
      West Sussex, UK
    • Related Report
      2011 Annual Research Report
  • [Presentation] 遅筋/心筋型魚類ミオシン重鎖遺伝子トラフグMYH_<M5>の組織特異的発現に関与するプロモーターの解析2010

    • Author(s)
      木下滋晴・Md.Asaduzzaman・小野陽介・Dadasaheb B.Akolkar・浅川修一・渡部終五
    • Organizer
      平成22年度日本水産学会春季大会
    • Place of Presentation
      藤沢
    • Year and Date
      2010-03-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] Promoter analysis of torafugu Takifugu rubripes myosin heavy chaingene MYH_<M743-2> in zebrafish embryos2010

    • Author(s)
      Md.Asaduzzaman・木下滋晴・小野陽介・Dadasaheb B.Akolkar・浅川修一・渡部終五
    • Organizer
      平成22年度日本水産学会春季大会
    • Place of Presentation
      藤沢
    • Year and Date
      2010-03-27
    • Related Report
      2009 Annual Research Report
  • [Presentation] ミオシン重鎖アイソフォームを用いた筋特異的プロモーターの解析2010

    • Author(s)
      木下滋晴・Md.Asaduzzaman・小野陽介・Dadasaheb B.Akolkar・浅川修一・渡部終五
    • Organizer
      2010年生体運動研究合同班会議
    • Place of Presentation
      東京
    • Year and Date
      2010-01-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] Functional analysis of myosin heavy chain genes in embryonic and post-embryonic muscle growth of torafugu Takifugu rubripes2010

    • Author(s)
      Watabe S
    • Organizer
      9th International Congress on the Biology of Fish
    • Place of Presentation
      Barcelona, Spain
    • Related Report
      2011 Final Research Report
  • [Presentation] Genomic structural and functional analyses of pufferfish2010

    • Author(s)
      Watabe S
    • Organizer
      9^<th> International Marine Biotechnology Conference(IMBC2010)
    • Place of Presentation
      青島,中国
    • Related Report
      2011 Final Research Report
  • [Presentation] 5'-flanking region of the myosin heavy chain gene can induce fiber type-specific gene expression in fish muscle2010

    • Author(s)
      Kinoshita S, Asaduzzaman M, Ono Y, Akolkar DB, Ikeda D, Asakawa S, Watabe S
    • Organizer
      9th International Congress on the Biology of Fish
    • Place of Presentation
      Barcelona, Spain
    • Related Report
      2010 Annual Research Report
  • [Presentation] Functional analysis of myosin heavy chain genes in embryonic and post-embryonic muscle growth of torafugu Takifugu rubripes2010

    • Author(s)
      Watabe S
    • Organizer
      9th International Congress on the Biology of Fish
    • Place of Presentation
      Barcelona, Spain(招待講演)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Genomic structural and functional analyses of pufferfish2010

    • Author(s)
      Watabe S
    • Organizer
      9th International Marine Biotechnology Conference(IMBC2010)
    • Place of Presentation
      青島, 中国(基調講演)
    • Related Report
      2010 Annual Research Report
  • [Presentation] Comprehensive analysis of torafugu Takifugu rubripes myosin heavy chain genes and their expression patterns during muscle differentiation and growth in relation to fish lineage2009

    • Author(s)
      Watabe S, Kinoshita S, Akolkar DB, Ikeda D
    • Organizer
      International symposium of marine genomics
    • Place of Presentation
      沖縄
    • Year and Date
      2009-12-15
    • Related Report
      2011 Final Research Report
  • [Presentation] Comprehensive analysis of torafugu Takifugu rubripes myosin heavy chain genes and their expression patterns during muscle differentiation and growth in relation to fish lineage(招待講演)2009

    • Author(s)
      Shugo Watabe, Shigeharu Kinoshita, Dadasaheb B.Akolker, Daisuke Ikeda
    • Organizer
      International symposium of marine genomics
    • Place of Presentation
      那覇
    • Year and Date
      2009-12-15
    • Related Report
      2009 Annual Research Report
  • [Presentation] Comprehensive analysis of myosin heavy chain genes from torafugu Takifugu rubripes and their expression patterns in embryos and adult skeletal muscle fibers2009

    • Author(s)
      Watabe S
    • Organizer
      JSPS-NRCT Joint Seminar 2009
    • Place of Presentation
      Rayong, Thailand
    • Year and Date
      2009-12-14
    • Related Report
      2011 Final Research Report
  • [Presentation] Comprehensive analysis of myosin heavy chain genes from torafugu Takifugu rubripes and their expression patterns in embryos and adult skeletal muscle fibers2009

    • Author(s)
      Shugo Watabe
    • Organizer
      JSPS-NRCT Joint Seminar 2009"Strengthening the Advancement in Fishery Research : Towards the Sustainable Cooperation"
    • Place of Presentation
      Province, Thailand
    • Year and Date
      2009-12-14
    • Related Report
      2009 Annual Research Report
  • [Presentation] 魚類の表層遅筋および心筋に特異的な遣伝子発現に必要な転写制御領域の解析2009

    • Author(s)
      木下滋晴・Md.Asaduzzaman・小野陽介・Dadasaheb B.Akolkar・浅川修一・渡部終五
    • Organizer
      平成21年度日本水産学会秋季大会
    • Place of Presentation
      岩手
    • Year and Date
      2009-10-01
    • Related Report
      2009 Annual Research Report
  • [Presentation] Identification functional analysis of the promoter region in the torafugu myosin heavy chain gene, MYH_<M5>, involved in cardiac and superficial slow muscle specific expressions2009

    • Author(s)
      Shigeharu Kinoshita, Yuya Sugano, Yosuke Ono, Shugo Watabe
    • Organizer
      6^<th> European Zebrafish Genetics and Development Meeting
    • Place of Presentation
      Romaイタリア
    • Year and Date
      2009-07-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] The spatio-temporal expression of sarcomeric myosin heavy chain genes during muscle development of medaka Oryzias latipes are regulated by their 5^'-flanking region as revealed by transgenic constructs2009

    • Author(s)
      Yosuke Ono, Shigeharu Kinoshita, Shugo Watabe
    • Organizer
      6^<th> European Zebrafish Genetics and Development Meeting
    • Place of Presentation
      Romaイタリア
    • Year and Date
      2009-07-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] Functional plasticity of fish myosin heavy chain genes and their spatial and temporal expression patterns2009

    • Author(s)
      Watabe S
    • Organizer
      International Symposium of Genomics in Aquaculture
    • Place of Presentation
      Bodo, Norway
    • Year and Date
      2009-07-05
    • Related Report
      2011 Final Research Report
  • [Presentation] Functional plasticity of fish myosin heavy chain genes and their spatial and temporal expression patterns2009

    • Author(s)
      Watabe S.
    • Organizer
      International Symposium of Genomics in Aquaculture
    • Place of Presentation
      Norway
    • Year and Date
      2009-07-05
    • Related Report
      2009 Self-evaluation Report
  • [Presentation] Functional plasticity of fish myosin heavy chain genes and their spatial and temporal expression patterns(招待講演)2009

    • Author(s)
      Shugo Watabe
    • Organizer
      International Symposium of Genomics in Aquaculture
    • Place of Presentation
      Bodo, Norway
    • Year and Date
      2009-07-05
    • Related Report
      2009 Annual Research Report
  • [Presentation] Myosin heavy chains responsible for temperature plasticity of fish muscle2009

    • Author(s)
      Watabe S
    • Organizer
      Annual Main Meeting 2009 of the Society for Experimental Biology
    • Place of Presentation
      Glasgow, UK
    • Year and Date
      2009-06-28
    • Related Report
      2011 Final Research Report
  • [Presentation] Myosin heavy chains responsible for temperature plasticity of fish muscle2009

    • Author(s)
      Watabe S.
    • Organizer
      Annual Main Meeting 2009 of the Society for Experimental Biology
    • Place of Presentation
      UK
    • Year and Date
      2009-06-28
    • Related Report
      2009 Self-evaluation Report
  • [Presentation] Myosin heavy chains responsible for temperature plasticity of fish muscle(招待講演)2009

    • Author(s)
      Shugo Watabe
    • Organizer
      Annual Main Meeting 2009 of the Society for Experimental Biology
    • Place of Presentation
      Glasgow, UK
    • Year and Date
      2009-06-28
    • Related Report
      2009 Annual Research Report
  • [Presentation] Expression patterns of multiple myosin heavy chain genes identify tissue-specific fibre types in adult skeletal muscles of torafugu Takifugu rubripes2009

    • Author(s)
      Dadasaheb B Akolkar, Shigeharu Kinoshita, Yosuke Ono, Shugo Watabe
    • Organizer
      Annual Main Meeting 2009 of the Society for Experimental Biology
    • Place of Presentation
      Glasgow, UK
    • Year and Date
      2009-06-28
    • Related Report
      2009 Annual Research Report
  • [Presentation] トラフグ・インスリン様成長因子1のイントロン配列および各種成長関連遺伝子の仔魚期における発現量と成長との関連2009

    • Author(s)
      古川聡史・黒須洋平・木下滋晴・金子 元・武島弘彦・西田 睦・渡部終五
    • Organizer
      平成21年度日本水産学会春季大会
    • Place of Presentation
      東京
    • Year and Date
      2009-03-29
    • Related Report
      2008 Annual Research Report
  • [Presentation] メダカ胚型ミオシン重鎖遺伝子の発現を制御する上流領域の解析2009

    • Author(s)
      小野陽介・木下滋暗・渡部終五
    • Organizer
      平成21年度日本水産学会春季大会
    • Place of Presentation
      東京
    • Year and Date
      2009-03-28
    • Related Report
      2008 Annual Research Report
  • [Presentation] トラフグTakifugu rubripes 成魚骨格筋における一筋原線維ATPase 活性の組織学的検討2009

    • Author(s)
      Dadasaheb B. Akolkar, Yosuke Ono, Shigeharu Kinoshita, Shugo Watabe
    • Organizer
      平成21年度日本水産学会春季大会
    • Place of Presentation
      東京
    • Year and Date
      2009-03-28
    • Related Report
      2008 Annual Research Report
  • [Presentation] 魚類の心筋および遅筋に特異的なプロモーターの単離と機能解析2009

    • Author(s)
      木下滋晴・菅野雄耶・小野陽介・渡部終五
    • Organizer
      平成21年度日本水産学会春季大会
    • Place of Presentation
      東京
    • Year and Date
      2009-03-28
    • Related Report
      2008 Annual Research Report
  • [Presentation] メダカ胚発生における骨格筋型ミオシン重鎖の発現制御機構2009

    • Author(s)
      小野陽介・木下滋晴・渡部終五
    • Organizer
      生体運動研究合同班会議2009
    • Place of Presentation
      東京
    • Year and Date
      2009-01-10
    • Related Report
      2008 Annual Research Report
  • [Presentation] Fiber Type-specific transcriptional regulation in the expression of fish myosin heavy chain genes2008

    • Author(s)
      Kinoshita S, Ono Y, Ikeda D, Watabe S
    • Organizer
      WFC2008 5^th World Fisheries Congress
    • Place of Presentation
      横浜
    • Year and Date
      2008-10-23
    • Related Report
      2011 Final Research Report
  • [Presentation] Fiber type-specific transcriptional regulation in the expression of fish myosin heavy chain genes2008

    • Author(s)
      Kinoshita S., Ono Y., Ikeda D., Watabe S.
    • Organizer
      WFC2008 5^<th> World Fisheries Congress
    • Place of Presentation
      横浜
    • Year and Date
      2008-10-23
    • Related Report
      2009 Self-evaluation Report
  • [Presentation] Dominant Sarcomeric Myosin Heavy Chain Genes Expressed in Adult Fast, Slow and Cardiac Muscles in Torafugu Takifugu rubripes2008

    • Author(s)
      D. B. Akolkar, S. Kinoshita, L. Yasmin, Y. Ono, D. Ikeda, and S. Watabe
    • Organizer
      WFC2008 5^<th> World Fisheries Congress
    • Place of Presentation
      横浜
    • Year and Date
      2008-10-23
    • Related Report
      2008 Annual Research Report
  • [Presentation] Fiber Type-specific Transcriptional Regulation in the Expression of Fish Myosin Heavy Chain Genes2008

    • Author(s)
      S. Kinoshita, Y. Ono, D. Ikeda, and S. Watabe
    • Organizer
      WFC2008 5^<th> World Fisheries Congress
    • Place of Presentation
      横浜
    • Year and Date
      2008-10-23
    • Related Report
      2008 Annual Research Report
  • [Presentation] Evolutionary Lineage of Fish Myosin Heavy Chain Genes as Revealed Comprehensive Analyses on Torafugu, Tetraodon, Zebrafish and Medaka Gnome Databases2008

    • Author(s)
      D.Ikeda, Y. Ono, and S. Watabe
    • Organizer
      WFC2008 5^<th> World Fisheries Congress
    • Place of Presentation
      横浜
    • Year and Date
      2008-10-23
    • Related Report
      2008 Annual Research Report
  • [Presentation] A 5'-flanking Region of the Myosin Heavy Chain Gene from Torafugu (Takifugu rubripes) Promotes Developmental Stage-specific Transcription2008

    • Author(s)
      L. Yasmin, S. Kinoshita, D. Ikeda, Y. Ono, D. B. Akolkar, and S. Watabe
    • Organizer
      WFC2008 5^<th> World Fisheries Congress
    • Place of Presentation
      横浜
    • Year and Date
      2008-10-23
    • Related Report
      2008 Annual Research Report
  • [Presentation] The regulation in the expression of sarcomeric myosin heavy chain genes during muscle development in medaka Oryzias latipes2008

    • Author(s)
      Y. Ono, S. Kinoshita, D. Ikeda, and S. Watabe
    • Organizer
      WFC2008 5^<th> World Fisheries Congress
    • Place of Presentation
      横浜
    • Year and Date
      2008-10-23
    • Related Report
      2008 Annual Research Report
  • [Presentation] メダカの筋発生におけるミオシン重鎮遺伝子MYHemblの発現制御と機能2008

    • Author(s)
      小野陽介・木下滋晴・渡部終五
    • Organizer
      第5回東京大学の生命科学シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2008-04-19
    • Related Report
      2008 Annual Research Report
  • [Presentation] cDNA cloning of myosin heavy chain genes and their expression patterns in adult fast, slow and cardiac muscles of torafugu Takiffugu rubripes2008

    • Author(s)
      Dadasaheb Akolkar・Yosuke Ono・Daisuke Ikeda・Shigeharu Kinoshita・Shugo Watabe
    • Organizer
      平成20年度日本水産学会春季大会
    • Place of Presentation
      静岡
    • Year and Date
      2008-03-28
    • Related Report
      2007 Annual Research Report
  • [Presentation] Cis-regulation of the myosin heavy chain gene from torafufu (Takifugu rubrilpes) directs the spatio-temporal expression during development2008

    • Author(s)
      Lubna Yasmin・Kinoshita Shigeharu・Daisuke Ikeda・Yosuke Ono・Shugo Watabe
    • Organizer
      平成20年度日本水産学会春季大会
    • Place of Presentation
      静岡
    • Year and Date
      2008-03-28
    • Related Report
      2007 Annual Research Report
  • [Presentation] ミオシン重鎖アイフォームを利用した魚類遅筋および心筋細胞の可視化2008

    • Author(s)
      木下 滋晴・小野 陽介・池田 大介・渡部 終五
    • Organizer
      平成20年度日本水産学会春季大会
    • Place of Presentation
      静岡
    • Year and Date
      2008-03-28
    • Related Report
      2007 Annual Research Report
  • [Presentation] 筋形成に関与するメダカ・ミオシン重鎖遺伝子の発現調節機構2008

    • Author(s)
      小野 陽介・木下 滋晴・池田 大介・渡部 終五
    • Organizer
      平成20年度日本水産学会春季大会
    • Place of Presentation
      静岡
    • Year and Date
      2008-03-28
    • Related Report
      2007 Annual Research Report
  • [Presentation] Cis-regulation in the spatio-temporal expression of the slow/cardiac-type torafugumyosin heavy chain gene2008

    • Author(s)
      木下 滋晴・山本 哲也・酒井 翔太・渡部 終五
    • Organizer
      Plant and Animal Genome XVI Conference
    • Place of Presentation
      アメリカ・サンディエゴ
    • Year and Date
      2008-01-14
    • Related Report
      2007 Annual Research Report
  • [Presentation] ミオシン重鎖アイソフォームを利用した魚類遅筋線維および心筋細胞の可視化2008

    • Author(s)
      木下 滋晴・小野 陽介・池田 大介・渡部 終五
    • Organizer
      生体運動合同班会議
    • Place of Presentation
      仙台
    • Year and Date
      2008-01-07
    • Related Report
      2007 Annual Research Report
  • [Presentation] メダカMyo Dfamily遺伝子myf5の筋形成における機能解析2007

    • Author(s)
      冨塚 達也・小野 陽介・木下 滋晴・渡部 終五
    • Organizer
      平成19年度日本水産学会秋季大会
    • Place of Presentation
      函館
    • Year and Date
      2007-09-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] Functional analysis of the 5'-regulatory region of the myosin heavy chain gene from torafhgu Takifugu rubripes in their spatio-temporal expression2007

    • Author(s)
      Lubna Yasmin・Kinoshita Shigeharu・Daisuke Ikeda・Yosuke Ono・Shugo Watabe
    • Organizer
      平成19年度日本水産学会秋季大会
    • Place of Presentation
      函館
    • Year and Date
      2007-09-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] メダカ・ミオシン重鎖遺伝子の発現解析による魚類に特徴的な筋形成メカニズムの検討2007

    • Author(s)
      小野 陽介・木下 滋晴・池田 大介・渡部 終五
    • Organizer
      東京大学生命科学研究ネットワークシンポジウム2007
    • Place of Presentation
      東京
    • Year and Date
      2007-09-15
    • Related Report
      2007 Annual Research Report
  • [Book] Matsunaga S. Chemistry of aquatic organisms and their utilization. Introduction for Fisheries and Aquatic Biology2011

    • Author(s)
      Abe H, Watabe S, Ochiai Y, Okada S, Yoshikawa N, Kinoshita S, Kaneko G, Matsunaga S
    • Publisher
      Terapub
    • Related Report
      2011 Final Research Report
  • [Book] Molecular biotechnology of development and growth in fish muscle. Fisheries for Global Welfare and Environment2008

    • Author(s)
      Johnston IA, Macqueen DJ, Watabe S
    • Publisher
      Terapub
    • Related Report
      2011 Final Research Report
  • [Book] Fisheries for Global Welfare and Environment(Tsukamoto K., Kawamura T., Takeuchi T., Beard T. D., and Kaiser M. J., eds, Molecular biotechnology of development and growth in fish muscle.)2008

    • Author(s)
      Johnston I. A, Macqueen D. J., Watabe S.
    • Publisher
      Terrapub
    • Related Report
      2009 Self-evaluation Report
  • [Book] Molecular biotechnology of development and growth in fish muscle. Fisheries fbr Gldbal Welfhre and Environment(Katsumi Tsukamoto, Tomohiko Kawamura, ToshioTakeuchi, Thomas D. Beard, and Michel J. Kaiser, eds)2008

    • Author(s)
      Ian A. Johnston, Daniel J. Macqueen, and Shugo Watabe
    • Publisher
      Terrapub
    • Related Report
      2008 Annual Research Report
  • [Remarks]

    • URL

      http://mbl.fs.a.u-tokyo.ac.jp/index.html

    • Related Report
      2011 Final Research Report
  • [Remarks]

    • URL

      http://mbl.fs.a.u-tokyo.ac.jp/index.html

    • Related Report
      2011 Annual Research Report

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

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