| Budget Amount *help |
¥96,980,000 (Direct Cost: ¥74,600,000、Indirect Cost: ¥22,380,000)
Fiscal Year 2011: ¥15,600,000 (Direct Cost: ¥12,000,000、Indirect Cost: ¥3,600,000)
Fiscal Year 2010: ¥17,160,000 (Direct Cost: ¥13,200,000、Indirect Cost: ¥3,960,000)
Fiscal Year 2009: ¥17,160,000 (Direct Cost: ¥13,200,000、Indirect Cost: ¥3,960,000)
Fiscal Year 2008: ¥19,370,000 (Direct Cost: ¥14,900,000、Indirect Cost: ¥4,470,000)
Fiscal Year 2007: ¥27,690,000 (Direct Cost: ¥21,300,000、Indirect Cost: ¥6,390,000)
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| Research Abstract |
We have previously reported that small GTPase OsRac1 plays important roles in rice innate immunity. However, it is largely unknown how OsRac1 induces immune responses. In this study, we showed that OsRac1 forms a complex termed Defensome with various downstream proteins, including R proteins, pattern recognition receptors, a scaffolding protein, and cochaperone proteins. OsRac1 also plays a dual role in the induction of ROS production through direct interactions with NADPH oxidases and the suppression of the ROS scavenger. Moreover, we demonstrate here that Defensome acts as an important regulator in rice innate immunity.
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