| Budget Amount *help |
¥26,390,000 (Direct Cost: ¥20,300,000、Indirect Cost: ¥6,090,000)
Fiscal Year 2010: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2009: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Fiscal Year 2008: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2007: ¥16,120,000 (Direct Cost: ¥12,400,000、Indirect Cost: ¥3,720,000)
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| Research Abstract |
Understanding of modes of interactions between drugs and proteins is important to promote drug discovery and studies on side-effects of drugs. Although it is not practically possible to measure all the interactions experimentally, in silico methods are expected to become viable alternatives. In this project, we have studied novel methodologies essential for this purpose, and applied them to evaluate the interactions between commercially available drugs and proteins which are closely related to carbohydrate metabolism.
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