• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Neural mechanisms for perception of harmony in the auditory cortex

Research Project

Project/Area Number 19200025
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Neuroscience in general
Research InstitutionNiigata University

Principal Investigator

SHIBUKI Katsuei  Niigata University, 脳研究所, 教授 (40146163)

Co-Investigator(Kenkyū-buntansha) IWASATO Takuji  遺伝学研究所, 個体遺伝研究系, 教授 (00311332)
KUDOH Masaharu  帝京大学, 医学部, 教授 (80153310)
菱田 竜一  新潟大学, 脳研究所, 准教授 (90313551)
八木 健  大阪大学, 生命機能研究科, 教授 (10241241)
Co-Investigator(Renkei-kenkyūsha) YAGI Takeshi  大阪大学, 生命科学研究科, 教授 (10241241)
HISHIDA Ryuichi  新潟大学, 脳研究所, 准教授 (90313551)
TOHMI Manabu  新潟大学, 脳研究所, 助教 (10401770)
Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥49,270,000 (Direct Cost: ¥37,900,000、Indirect Cost: ¥11,370,000)
Fiscal Year 2009: ¥15,210,000 (Direct Cost: ¥11,700,000、Indirect Cost: ¥3,510,000)
Fiscal Year 2008: ¥15,210,000 (Direct Cost: ¥11,700,000、Indirect Cost: ¥3,510,000)
Fiscal Year 2007: ¥18,850,000 (Direct Cost: ¥14,500,000、Indirect Cost: ¥4,350,000)
Keywordsフラビン蛋白蛍光 / 経頭蓋イメージング / 聴覚野 / 和音 / マウス / 経頭蓋メージング / Tonotopic map / FM音 / 差分イメージング / Tonotopic Map / 不協和音 / 経験依存的可塑性 / モザイク音 / 光不活化
Research Abstract

和音とは基音(F0)の整数倍の倍音の組み合わせからなり、和音を聴くと、その中にF0が含まれていない場合でもF0を知覚するので、F0応答を手掛かりに和音の識別メカニズムを探索することができる。我々はマウス聴覚野のF0に対する応答を経頭蓋フラビン蛋白蛍光イメージングによって可視化した。さらにこのF0応答の生ずるメカニズムを解析したところ経験依存的に形成された皮質内回路の働きによるものであることが判った。

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (39 results)

All 2010 2009 2008 2007 Other

All Journal Article (22 results) (of which Peer Reviewed: 16 results) Presentation (10 results) Book (3 results) Remarks (4 results)

  • [Journal Article] Cortical depression in the mouse auditory cortex after sound discrimination learning2010

    • Author(s)
      Ohshima S, Tsukano H, Kubota Y, Takahashi K, Hishida R, Takahashi S, Shibuki K
    • Journal Title

      Neurosci Res 67

      Pages: 51-58

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] ranscranial imaging of somatotopic map plasticity after tail cut in mice2010

    • Author(s)
      Kitaura H, Hishida R, Shibuki K
    • Journal Title

      Brain Res 1319

      Pages: 54-59

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Transcranial imaging of somatotopic map plasticity after tail cut in mice.2010

    • Author(s)
      Kitaura H, Hishida R, Shibuki K
    • Journal Title

      Brain research 1319

      Pages: 54-59

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cortical depression in the mouse auditory cortex after sound discrimination learning.2010

    • Author(s)
      Ohshima S, Shibuki K, 他5名
    • Journal Title

      Neuroscience research (In press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Transcranial flavoprotein fluorescence imaging of mouse cortical activity and plasticity2009

    • Author(s)
      Tohmi M, Takahashi K, Kubota Y, Hishida R, Shibuki K
    • Journal Title

      J Neurochem 1

      Pages: 3-9

    • Related Report
      2009 Final Research Report
  • [Journal Article] マウス大脳皮質感覚野の経験による修飾2009

    • Author(s)
      澁木克栄、吉武講平、駒形成司、塚野浩明、大島伸介、渡邉健児、任海学、菱田竜一
    • Journal Title

      生体の科学(金原書店) 60巻

      Pages: 75-80

    • Related Report
      2009 Final Research Report
  • [Journal Article] Activity dependent glial swelling is impaired in aquaporin-4 knockout mice2009

    • Author(s)
      Kitaura H, Tsujita M, Kakita A, Shibuki K, Sakimura K, Kwee KL, Nakada T
    • Journal Title

      Neurosci Res 64

      Pages: 208-212

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Transcranial flavoprotein fluorescence imaging of mouse cortical activity and plasticity.2009

    • Author(s)
      Tohmi M, Shibuki K, 他3名
    • Journal Title

      Journal of Neurochemistry 109 Suppl 1

      Pages: 3-9

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Transcranial flavoprotein fluorescence imaging of mouse cortical activity and plasticity2009

    • Author(s)
      Tohmi M, 他4名
    • Journal Title

      Journal of Neurochemistry (in press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Activity dependent glial swelling is impaired in aquaporin-4 knockout mice2009

    • Author(s)
      Kitaura H, 他6名
    • Journal Title

      Neuroscience Research (in press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] マウス大脳皮質感覚野の経験による修飾2009

    • Author(s)
      澁木克栄, 他7名
    • Journal Title

      生体の科学 60

      Pages: 75-80

    • Related Report
      2008 Annual Research Report
  • [Journal Article] Transcranial photo-inactivation of neural activities in the mouse auditory cortex2008

    • Author(s)
      Kubota Y, Kamatani D, Tsukano H, Ohshima S, Takahashi K, Hishida R, Kudoh M, Takahashi S, Shibuki K
    • Journal Title

      Neurosci Res 60

      Pages: 422-430

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] 新しい光学的測定法による大脳聴覚野の機能解析-フラビン蛋白蛍光イメージング法-2008

    • Author(s)
      高橋姿、高橋邦行、窪田和、大島伸介、澁木克栄
    • Journal Title

      耳鼻咽喉科展望 51(2)

      Pages: 4-81

    • Related Report
      2009 Final Research Report
  • [Journal Article] 感覚野経験依存的可塑性の経頭蓋蛍光イメージング2008

    • Author(s)
      澁木克栄、駒形成司、吉武講平、塚野浩明、菱田竜一
    • Journal Title

      蛋白質核酸酵素 53巻増刊号

      Pages: 512-517

    • Related Report
      2009 Final Research Report
  • [Journal Article] Transcranial photo-inactivation of neural activities in the mouse auditory cortex.2008

    • Author(s)
      Kubota Y, 他8名
    • Journal Title

      Neurosicence Research 60

      Pages: 422-430

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 感覚野経験依存的可塑性の経頭蓋蛍光イメージング2008

    • Author(s)
      澁木克栄, 他4名
    • Journal Title

      蛋白質 核酸 酵素 53(No.4)

      Pages: 512-517

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Long-term depression induced by local tetanic stimulation in the rat auditory cortex2007

    • Author(s)
      Watanabe K, Kamatani D, Hishida R, Kudoh M, Shibuki K
    • Journal Title

      Brain Res 1166

      Pages: 20-28

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Roles of nitric oxide as a vasodilator in neurovascular coupling of mouse somatosensory cortex2007

    • Author(s)
      Kitaura H, Uozumi N, Tohmi M, Yamazaki M, Sakimura K, Kudoh M, Shimizu T, Shibuki K
    • Journal Title

      Neurosci Res 59

      Pages: 160-171

    • NAID

      10024417303

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Experience-dependent formation of activity propagation patterns at the somatosensory S1 and S2 boundary in rat cortical slices2007

    • Author(s)
      Kamatani D, Hishida R, Kudoh M, Shibuki K
    • Journal Title

      Neuroimage 35

      Pages: 47-57

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Functional local connections with differential activity-dependence and critical periods surrounding the primary auditory cortex in rat cerebral slices2007

    • Author(s)
      Hishida R, Kamatani D, Kitaura H, Kudoh M, Shibuki K
    • Journal Title

      Neuroimage 34

      Pages: 679-693

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Long-term depression induced by local tetanic stimulation in the rat auditory cortex.2007

    • Author(s)
      Watanabe K, 他4名
    • Journal Title

      Brain Research 1166

      Pages: 20-28

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Roles of nitric oxide as a vasodilator in neurovascular coupling of mouse somatosensory cortex.2007

    • Author(s)
      Kitaura H, 他7名
    • Journal Title

      Neurosicence Research 59

      Pages: 160-171

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] 酵素代謝を反映するフラビン蛋白蛍光を用いた脳機能イメージング2009

    • Author(s)
      澁木克栄
    • Organizer
      第13回酸素ダイナミクス研究会
    • Place of Presentation
      東京(島津製作所)
    • Year and Date
      2009-09-12
    • Related Report
      2009 Annual Research Report
  • [Presentation] Transcranial flavoprotein fluorescence imaging of experiencedependent cortical plasticity2008

    • Author(s)
      Shibuki K
    • Organizer
      The 3rd ISN Special Neurochemistry Conference 8th International Meeting on Brain Energy Metabolism
    • Place of Presentation
      Beijing, China
    • Year and Date
      2008-06-28
    • Related Report
      2009 Final Research Report
  • [Presentation] Transcranial flavoprotein fluorescence imaging of experience-dependent cortical plasticity2008

    • Author(s)
      Shibuki K
    • Organizer
      The 3rd ISN Special Neurochemistry Conference 8th International Meeting on Brain Energy Metabolism
    • Place of Presentation
      Beijing, China
    • Year and Date
      2008-06-28
    • Related Report
      2008 Annual Research Report
  • [Presentation] Transcranial flavoprotein fluorescence imaging of neural activities in the mouse auditory cortex after sound discrimination learning2007

    • Author(s)
      Ohshima S, 他4名
    • Organizer
      第12回聴覚研究フォーラム
    • Place of Presentation
      大津市
    • Year and Date
      2007-12-02
    • Related Report
      2007 Annual Research Report
  • [Presentation] Transcranial fluorescence imaging of cortical responses to harmonic and inharmonic sounds in the mouse auditory cortex.2007

    • Author(s)
      Tsukano H, 他4名
    • Organizer
      第12回聴覚研究フォーラム
    • Place of Presentation
      大津市
    • Year and Date
      2007-12-02
    • Related Report
      2007 Annual Research Report
  • [Presentation] 経頭蓋電気刺激を用いた麻酔下マウス皮質間結合の活性化2007

    • Author(s)
      菱田竜一, 他2名
    • Organizer
      第30回日本神経科学大会
    • Place of Presentation
      横浜市
    • Year and Date
      2007-09-13
    • Related Report
      2007 Annual Research Report
  • [Presentation] 末梢神経の自発発火阻止によって誘発されるマウス体性感覚野応答の増強2007

    • Author(s)
      駒形成司, 他4名
    • Organizer
      第30回日本神経科学大会
    • Place of Presentation
      横浜市
    • Year and Date
      2007-09-11
    • Related Report
      2007 Annual Research Report
  • [Presentation] 視覚空間情報とヒゲ空間情報の不一致で生ずる斜視マウス視覚野応答の抑圧2007

    • Author(s)
      吉武講平, 他3名
    • Organizer
      第30回日本神経科学大会
    • Place of Presentation
      横浜市
    • Year and Date
      2007-09-11
    • Related Report
      2007 Annual Research Report
  • [Presentation] マウスバレル野切片の視床刺激応答の経験依存的可塑性2007

    • Author(s)
      渡邉健児, 他4名
    • Organizer
      第30回日本神経科学大会
    • Place of Presentation
      横浜市
    • Year and Date
      2007-09-11
    • Related Report
      2007 Annual Research Report
  • [Presentation] 言語音認識機構のラットモデル:聴覚野に依存する合成言語音の弁別学習2007

    • Author(s)
      工藤雅治, 他3名
    • Organizer
      第30回日本神経科学大会
    • Place of Presentation
      横浜市
    • Year and Date
      2007-09-10
    • Related Report
      2007 Annual Research Report
  • [Book] Flavoprotein fluorescence imaging of experience-dependent cortical plasticity in rodents n In vivo optical imaging of brain function 2nd Edition (Frostig R ed).2009

    • Author(s)
      Shibuki K, Hishida R, Tohmi M, Takahashi K, Kitaura H, Kubota Y
    • Publisher
      ICRC Press
    • Related Report
      2009 Final Research Report
  • [Book] Flavoprotein fluorescence imaging of experience-dependent corticalplasticity in rodents. In : In Vivo Optical Imaging of Brain Function. 2nd Edition (Frostig R ed).2009

    • Author(s)
      Shibuki K, 他5名
    • Total Pages
      528
    • Publisher
      Chapman & Hall/CRC
    • Related Report
      2008 Annual Research Report
  • [Book] Handbook of Neurochemistry, Molecular Neurobiology(Coupling of brain function and metabolism)2007

    • Author(s)
      Shibuki K, Hishida R, Kitaura H, Takahashi K, Tohmi M:
    • Publisher
      Springer
    • Related Report
      2009 Final Research Report
  • [Remarks]

    • URL

      http://www.bri.niigata-u.ac.jp/~physio/

    • Related Report
      2009 Final Research Report
  • [Remarks]

    • URL

      http://www.bri.niigata-u.ac.jp/~physio/

    • Related Report
      2009 Annual Research Report
  • [Remarks]

    • URL

      http://www.bri.niigata-u.ac.jp/~physio/

    • Related Report
      2008 Annual Research Report
  • [Remarks]

    • URL

      http://www.bri.niigata-u.ac.jp/~physio/

    • Related Report
      2007 Annual Research Report

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi