| Project/Area Number |
19208024
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| Research Category |
Grant-in-Aid for Scientific Research (A)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Zootechnical science/Grassland science
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| Research Institution | Kagoshima University |
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Principal Investigator |
HAYASHI Kunioki Kagoshima University, 農学部, 教授 (80041656)
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| Co-Investigator(Kenkyū-buntansha) |
HASEGAWA Shin 神戸大学, 大学院・農学研究科, 教授 (60107985)
KATO Kazo 東北大学, 大学院・農学研究科, 教授 (60091831)
OHTSUKA AKIRA 鹿児島大学, 農学部, 准教授 (10233173)
SUGAWARA KUNIO 宇都宮大学, 農学部, 教授 (50091947)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥49,400,000 (Direct Cost: ¥38,000,000、Indirect Cost: ¥11,400,000)
Fiscal Year 2009: ¥13,910,000 (Direct Cost: ¥10,700,000、Indirect Cost: ¥3,210,000)
Fiscal Year 2008: ¥13,780,000 (Direct Cost: ¥10,600,000、Indirect Cost: ¥3,180,000)
Fiscal Year 2007: ¥21,710,000 (Direct Cost: ¥16,700,000、Indirect Cost: ¥5,010,000)
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| Keywords | 飼料 / 生理活性物質 / 筋肉タンパク質分解 / 食欲制御 / 焼酎粕 / 成長促進物質 / ブトキシブチルアルコール / 焼酎粕因子 / 鶏 / 神経ペプチド / 視床下部 / 下垂体 / 摂食調節 |
|---|
| Research Abstract |
The present study showed that the growth promoter buthoxybuthyl alcohol (BBA) found from Shochu distillery by-product reduces muscle proteolysis. This effect of BBA was caused by decreases in genes expressions of factors relating to the skeletal muscle proteolysis such as calpain, ubiquitin, and proteasome.
Furthermore, the present study showed changes in secretions of growth hormone (GH), adrenocorticotropic hormone (ACTH) and corticotropin-releasing hormone (CRH) due to BBA. BBA increased GH secretion and decreased secretions of ACTH and CRH. BBA increased feed intake because CRH is reduced followed by nerve peptides synthesis in the hypothalamus.
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