|Budget Amount *help
¥48,100,000 (Direct Cost: ¥37,000,000、Indirect Cost: ¥11,100,000)
Fiscal Year 2010: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
Fiscal Year 2009: ¥9,490,000 (Direct Cost: ¥7,300,000、Indirect Cost: ¥2,190,000)
Fiscal Year 2008: ¥12,740,000 (Direct Cost: ¥9,800,000、Indirect Cost: ¥2,940,000)
Fiscal Year 2007: ¥17,810,000 (Direct Cost: ¥13,700,000、Indirect Cost: ¥4,110,000)
In this research project, the possibility of utilization of an antibacterial monomer MDPB for various treatment modalities in the field of conservative dentistry was examined. It was found that MDPB-containing dentin bonding system was effective to preserve pulp vitality in direct pulp capping therapy. The prototypes of antibacterial root canal filling system, multi-purpose conditioning agent for adhesion, and sealing resin were successfully achieved by incorporation of MDPB. In addition, no development of resistance against MDPB by oral bacteria was confirmed, suggesting the benefits of usage of MDPB as the antimicrobial.