Budget Amount *help |
¥18,980,000 (Direct Cost: ¥14,600,000、Indirect Cost: ¥4,380,000)
Fiscal Year 2009: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2008: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2007: ¥7,930,000 (Direct Cost: ¥6,100,000、Indirect Cost: ¥1,830,000)
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Research Abstract |
In order to examine the novel mechanism of neuropathic pain, we have used the rat model of neuropathic pain and explored the expression and the role of several molecules in nociceptive pathway. As a result, we have found that some intracellular signaling molecules, ATP receptors and some cytokines have important roles in dorsal root ganglion neurons, spinal dorsal horn neurons and spinal glial cells. These results were published in international high-level journals. We believe that these findings are expected as novel seeds for development of new therapeutic drug of neuropathic pain.
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