Development of Chemical Release Controlling Devices for Differentiation Induction of Neural Stem Cells
Project/Area Number |
19300161
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Biomedical engineering/Biological material science
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Research Institution | Kyushu Institute of Technology |
Principal Investigator |
YASUDA Takashi Kyushu Institute of Technology, 大学院・生命体工学研究科, 准教授 (80270883)
|
Project Period (FY) |
2007 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000)
Fiscal Year 2010: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2009: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2008: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2007: ¥7,930,000 (Direct Cost: ¥6,100,000、Indirect Cost: ¥1,830,000)
|
Keywords | マイクロ流体デバイス / マイクロ流路 / 微小孔 / マイクロバルブ / 神経幹細胞 / 細胞刺激 / 分化誘導 / ナノバイオ / ナノホール / マイクロフルイディクス |
Research Abstract |
Techniques of chemical release control for differentiation induction of neural stem cells were developed. First, four nanohole arrays and microvalves were fabricated at the bottom of a cell-culturing chamber, and chemical release from the nanoholes was controlled by switching open/close of the microvalves. Next, a sheathflow was generated in a microchannel under a chamber, and chemical release from microholes was controlled by regulating flow rates of three fluids which form the sheathflow. Moreover, in order to permit multiple chemicals to be released on a single device, 64 chambers were arranged in an 8 x 8 matrix, and each of 8 microchannels was located directly under a row of chambers.
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Report
(6 results)
Research Products
(37 results)
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[Journal Article]2009
Author(s)
安田隆
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Journal Title
MEMSデバイス総論(サイエンス & テクノロジー(株))
Pages: 89-103
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