Evaluation of Angiogenesis by High Resolution Three-dimensional Ultrasound Molecular Imaging
Project/Area Number |
19300179
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Medical systems
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Research Institution | Tohoku University |
Principal Investigator |
SAIJO Yoshifumi Tohoku University, 大学院・医工学研究科, 教授 (00292277)
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Co-Investigator(Kenkyū-buntansha) |
SATO Yasufumi 東北大学, 加齢医学研究所, 教授 (50178779)
KODAMA Tetsuya 東北大学, 大学院・医工学研究科, 教授 (40271986)
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Project Period (FY) |
2007 – 2009
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Project Status |
Completed (Fiscal Year 2009)
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Budget Amount *help |
¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000)
Fiscal Year 2009: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2008: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2007: ¥10,270,000 (Direct Cost: ¥7,900,000、Indirect Cost: ¥2,370,000)
|
Keywords | 超音波医科学 / 超音波 / 血管新生 / 三次元画像 / 分子イメージング / ナノバブル |
Research Abstract |
High resolution three-dimensional ultrasound molecular imaging was developed for evaluation of angiogenesis in small animals such as mice. The following were achieved ; 1. Three-dimensional ultrasound imaging system with the frequency range up to 150 MHz and the spatial resolution of 10 micron, 2. Image analysis algorithm for classification of vessels and surrounding tissues by correlation of RF signals in the consecutive frames, 3. Portable scanner for easy and repetitive use, 4. Molecular imaging of angiogenesis with labeled nano-bubble.
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Report
(4 results)
Research Products
(87 results)
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[Journal Article] Morphological approach for the functional improvement of an artificial myocardial assist device using shape memory alloy fibres2007
Author(s)
Shiraishi Y, Yambe T, Saijo Y, Sato F, Tanaka A, Yoshizawa M, Ogawa D, Wada Y, Itoh S, Sakata R, Park Y, Uematsu M, Umezu M, Fujimoto T, Masumoto N, Liu H, Baba A, Konno S, Nitta S, Imachi K, Tabayashi K, Sasada H, Homma D.
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Journal Title
Conf Proc IEEE Eng Med Biol Soc. Vol. 1
Pages: 3974-7
Related Report
Peer Reviewed
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[Journal Article] Macrophage colony-stimulating factor improves cardiac function after ischemic injury by inducing vascular endothelial growth factor production and survival of cardiomyocytes2007
Author(s)
Okazaki T, Ebihara S, Asada M, Yamanda S, Saijo Y, Shiraishi Y, Ebihara T, Niu K, Mei H, Arai H, Yambe T.
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Journal Title
Am J Pathol. Vol. 171, No. 4
Pages: 1093-1103
Related Report
Peer Reviewed
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[Presentation] 皮膚組織の3次元超音波顕微鏡像2008
Author(s)
西條芳文, 岩本貴宏, 小林和人, 岡田長也, 萩原嘉廣, 田中明, 穂積直裕
Organizer
第35回日本超音波医学会東北地方会
Place of Presentation
仙台
Year and Date
2008-03-23
Related Report
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