Development of Total Liquid Ventilation System Which Enables Active Medicine Treatment for Serious Patients with Respiratory Failure
| Project/Area Number |
19300187
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Medical systems
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| Research Institution | Tokyo Denki University |
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Principal Investigator |
FUNAKUBO Akio Tokyo Denki University, 理工学部, 教授 (00307670)
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| Co-Investigator(Kenkyū-buntansha) |
OHGOE Yasuharu 東京電機大学, 理工学部, 助手 (10408643)
FUKUI Yasuhiro 東京電機大学, 理工学部, 教授 (60112877)
YAGUCHI Toshiyuki 東京電機大学, 理工学部, 助手 (70385483)
SUMIKUA Hirohito 東京電機大学, フロンティア共同研究センター, 助手 (20433998)
KOMORI Eisaku 独立行政法人四国がんセンター, 臨床研究部, 医師 (40416475)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥15,210,000 (Direct Cost: ¥11,700,000、Indirect Cost: ¥3,510,000)
Fiscal Year 2009: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2008: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2007: ¥7,670,000 (Direct Cost: ¥5,900,000、Indirect Cost: ¥1,770,000)
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| Keywords | 液体呼吸 / 呼吸不全 / 能動的治療 / 人工肺 / ガス交換能 / 気道内圧制御 / 能動的治療法 / Perfluorocarbon / 多目的遺伝アルゴリズム / 完全液体呼吸 / 数値流体解析 / 重症呼吸不全 / 肺コンプライアンス |
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| Research Abstract |
The purpose of this study was to develop a Total Liquid Ventilation (TLV) system with high safety which does not damage living lungs. The respiratory conditions in ex-vivo were examined using the Japanese white rabbit for evaluation of the developed TLV system. As a result, the PO_2 and the PCO_2 levels were successfully maintained in normal range, and it was confirmed that the developed TLV system could perform prolonged application.
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Report
(4 results)
Research Products
(50 results)
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[Presentation] 人工肺2008
Author(s)
舟久保 昭夫
Organizer
第24回日本人工臓器学会教育セミナー「人工臓器」
Place of Presentation
東京(東京女子医科大学)
Year and Date
2008-07-12
Related Report
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[Presentation] Study on CO2 Removal of Total Liquid Ventilation System with Recirculation Circuit2008
Author(s)
T. Horikoshi, A. Funakubo, T. Konrai, K. Hasegawa, K. Fukunaga, E. Komori, S. Tredici, R. B Hirshl, R. H Bartlerr, Y. Fukui
Organizer
ASAIO Abstracts for the 54th Annual Conference
Place of Presentation
(SAN FRANCISCO, US)
Related Report
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