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Integrative responses between peripheral reflexes and the effects of exercise training

Research Project

Project/Area Number 19300215
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Sports science
Research InstitutionUniversity of Tsukuba

Principal Investigator

NISHIYASU Takeshi  University of Tsukuba, 大学院・人間総合科学研究科, 准教授 (90237751)

Co-Investigator(Kenkyū-buntansha) HONDA Yasushi  筑波大学, 大学院・人間総合科学研究科, 教授 (20165616)
SAITO Mitsuru  豊田工業大学, 工学部, 教授 (80126862)
Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥20,150,000 (Direct Cost: ¥15,500,000、Indirect Cost: ¥4,650,000)
Fiscal Year 2009: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2008: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2007: ¥13,130,000 (Direct Cost: ¥10,100,000、Indirect Cost: ¥3,030,000)
Keywordsトレーニング科学 / 息止め / 筋代謝受容器反射 / 膝伸展運動 / 筋代謝受容器 / 心拍変動 / 血圧変動 / 動脈圧受容器 / 運動
Research Abstract

We investigated the integrative responses among peripheral reflex mechanisms during orthostatic stress, breath-holding during exercise, and handgrip exercise in humans. 1) It was suggested that both the arterial baroreflex and local intrinsic vascular regulatory mechanisms contribute to the blood flow regulation in upper and lower limbs during orthostatic stress. 2) It was suggested that the muscle metaboreflex contributes to the increase in blood pressure response seen during breath-holding during dynamic exercise in humans. 3) It was suggested that the heart rate response to activation of muscle metaboreflex varies considerably from individual to individual, and that these differences reflect changes in cardiac parasympathetic tone and the sensitivity of the spontaneous arterial baroreflex control during the activation of muscle metaboreflex.

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (48 results)

All 2009 2008 2007

All Journal Article (19 results) (of which Peer Reviewed: 19 results) Presentation (28 results) Book (1 results)

  • [Journal Article] The cross-sectional relationships among hyperthermia-induced hyperventilation, peak oxygen consumption, and the cutaneous vasodilatory response during exercise.2009

    • Author(s)
      Hayashi K, Honda Y, Ogawa T, Kondo N, Nishiyasu T.
    • Journal Title

      European Journal of Applied Physiology 107(5)

      Pages: 527-534

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Baroreflex and muscle metaboreflex : control of muscle sympathetic nerve activity2008

    • Author(s)
      Ichinose M, Saito M, Kondo N, Nishiyasu T.
    • Journal Title

      Med Sci Sports Exerc. 40(12)

      Pages: 2037-45

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Modulation of the control of muscle sympathetic nerve activity during incremental leg cycling2008

    • Author(s)
      Ichinose M, Saito M, Fujii N, Ogawa T, Hayashi K, Kondo N, Nishiyasu T.
    • Journal Title

      J Physiol. 586(11)

      Pages: 2753-66

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Changes in blood flow in conduit artery and veins of the upper arm during leg exercise in humans2008

    • Author(s)
      Ooue A, Ichinose TK, Inoue Y, Nishiyasu T, Koga S, Kondo N.
    • Journal Title

      Eur J Appl Physiol. 103(3)

      Pages: 367-73

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] The effect of hypohydration on hyperthermic hyperpnea and cutaneous vasodilation during exercise in men2008

    • Author(s)
      Fujii N, Honda Y, Hayashi K, Kondo N, Nishiyasu T.
    • Journal Title

      J Appl Physiol. 105(5)

      Pages: 1509-18

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Baroreflex and muscle metaborenex: control of muscle sympathetic nerve actlVlty.2008

    • Author(s)
      Ichinose M, Saito M, Kondo N, Nishiyasu T.
    • Journal Title

      Med Sci Sports Exerc. 40(12)

      Pages: 2037-2045

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The effect of hypohydration on hyperthermic hyperpnea and cutaneous vasodilation during exercise in men.2008

    • Author(s)
      Fujii N, Honda Y, Hayashi K, Kondo N, Nishiyasu T.
    • Journal Title

      J Appl Physiol. 105(5)

      Pages: 1509-1518

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Modulation of the control of muscle sympathetic nerve actity during incremental leg cycling.2008

    • Author(s)
      Ichinose M, Saito M, Fujii N, Ogawa T, Hayashi K, Kondo N, Nishiyasu T.
    • Journal Title

      J Physiol. 586(11)

      Pages: 2753-2766

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Modulation of the spontaneous beat-to-beat fluctuations in peripheral vascular resistance during activation of muscle metaboreflex2007

    • Author(s)
      Ichinose M, Koga S, Fujii N, Kondo N, Nishiyasu T.
    • Journal Title

      Am J Physiol Heart Circ Physiol. 293(1)

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of posture on peripheral vascular responses to lower body positive pressure2007

    • Author(s)
      Nishiyasu T, Hayashida S, Kitano A, Nagashima K, Ichinose M.
    • Journal Title

      Am J Physiol Heart Circ Physiol. 293(1)

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Relationship between resting ventilatory chemosensitivity and maximal oxygen uptake in moderate hypobaric hypoxia2007

    • Author(s)
      Ogawa T, Hayashi K, Ichinose M, Nishiyasu T
    • Journal Title

      Journal of Applied Physiology 103(4)

      Pages: 1221-6

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Metabolic response during intermittent graded sprint running in moderate hypobaric hypoxia in competitive middle-distance runners2007

    • Author(s)
      Ogawa T, Hayashi K, Ichinose M, Wada H, Nishiyasu T
    • Journal Title

      European Journal of Applied Physiology 99(1)

      Pages: 39-46

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] ハンドグリップ運動時及び運動後虚血時における循環反応に対する体温上昇の影響2007

    • Author(s)
      西保岳, 丹信介, 曽根涼子, 林恵嗣, 一之瀬真志
    • Journal Title

      筑波大学体育科学系紀要 39

      Pages: 161-8

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of posture on peripheral vascular responses to lower body positive pressure2007

    • Author(s)
      Nishiyasu T, Hayashida S, Ichinose M
    • Journal Title

      Am. J. Physiol. 293(1)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Modulation of the spontaneous beat-to-beat fluctuations in peripheral vascular resistance during activation of muscle metaboreflex.2007

    • Author(s)
      Ichinose M, Koga S, Kondo N, Nishiyasu T
    • Journal Title

      Am. J. Physiol. 293(1)

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relationship between resting ventilatory chemosensitivity and maximal oxygen uptake in moderate hypobaric hypoxia.2007

    • Author(s)
      Ogawa T, Hayashi K, Ichinose M, Nishiyasu T
    • Journal Title

      J. Appl. Physiol. 103(4)

      Pages: 1221-6

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Metabolic response during intermittent graded sprint running in moderate hypobaric hypoxia in competitive middle-distance runners.2007

    • Author(s)
      Ogawa T, Hayashi K, Ichinose M, Wada H, Nishiyasu T
    • Journal Title

      Eur J Appl Physiol. 99(1)

      Pages: 39-46

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Changes in blood flow in a conduit artery and superficial vein of the upper arm during passive heating in humans.2007

    • Author(s)
      Ooue A, Ichinose-Kuwahara T, Shamsuddin AK, Inoue Y, Nishiyasu T, Koga S, Kondo N.
    • Journal Title

      Eur J Appl Physiol. 101(1)

      Pages: 97-103

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ハンドグリップ運動時及び運動後虚血時における循環反応に対する体温上昇の影響2007

    • Author(s)
      西保 岳、丹 信介、曽根涼子、林 恵嗣、一之瀬真志
    • Journal Title

      筑波大学体育科学系紀要 39

      Pages: 161-8

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] The Characteristics of Hyperthermic Hyperpnea at Rest and during Exercise in Humans Seminar in Department of Biomedical Physiology and Kinesiology2009

    • Author(s)
      Nishiyasu T.
    • Organizer
      Simon Fraser University
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2009-11-03
    • Related Report
      2009 Final Research Report
  • [Presentation] The Characteristics of Hyperthermic Hyperpnea at Rest and during Exercise in Humans2009

    • Author(s)
      西保岳
    • Organizer
      Seminar in Department of Biomedical Physiology and Kinesiology
    • Place of Presentation
      Simon Fraser University, Vancouver,(Canada)
    • Year and Date
      2009-11-03
    • Related Report
      2009 Annual Research Report
  • [Presentation] ヒト活動時の血圧調節-末梢性反射調節の複合作用2009

    • Author(s)
      西保岳
    • Organizer
      スポーツサイエンス研究会
    • Place of Presentation
      早稲田大学
    • Year and Date
      2009-09-15
    • Related Report
      2009 Final Research Report
  • [Presentation] ヒト活動時の血圧調節-末梢性反射調節の複合作用2009

    • Author(s)
      西保岳
    • Organizer
      スポーツサイエンス研究会
    • Place of Presentation
      早稲田大学(東京)
    • Year and Date
      2009-09-15
    • Related Report
      2009 Annual Research Report
  • [Presentation] Regulation of blood pressure during exercise : Interactions between arterial baroreflex and muscle metaboreflex2009

    • Author(s)
      Ichinose M, Nishiyasu T.
    • Organizer
      International Sports Science Network Forum in Nagano
    • Place of Presentation
      Nagano, Japan
    • Year and Date
      2009-08-02
    • Related Report
      2009 Final Research Report
  • [Presentation] Regulation of blood pressure during exercise : Interactions between arterial baroreflex and muscle metaboreflex2009

    • Author(s)
      Ichinose M, Nishiyasu T.
    • Organizer
      International Sports Science Network Forum in Nagano
    • Place of Presentation
      軽井沢(長野)
    • Year and Date
      2009-08-02
    • Related Report
      2009 Annual Research Report
  • [Presentation] The Characteristics of Hyperthermic Hyperpnea at Rest and during Exercise in Humans2009

    • Author(s)
      Nishiyasu T.
    • Organizer
      The 3rd International Symposium on Physiology and Pharmacology of Temperature Regulation
    • Place of Presentation
      Matsue, Japan
    • Year and Date
      2009-07-21
    • Related Report
      2009 Final Research Report
  • [Presentation] Regulation of blood pressure and sympathetic nerve activity during exercise in humans-muscle metaboreflex and arterial baroreflex function-2008

    • Author(s)
      Nishiyasu T, Saito M, Kondo N, Ichinose M.
    • Organizer
      2008 Korean Society of Exercise Physiology Summer Conference
    • Place of Presentation
      Daegu, Korea
    • Year and Date
      2008-06-21
    • Related Report
      2009 Final Research Report 2008 Annual Research Report
  • [Presentation] Regulation of blood pressure and sympathetic nerve activity during exercise in humans-muscle metaboreflex and arterial baroreflex function-2008

    • Author(s)
      Nishiyasu T, Fujii N, Hayashi K, Ichinose M.
    • Organizer
      Seminar Series of Department of Human Physiology
    • Place of Presentation
      University of Oregon, Eugene USA
    • Year and Date
      2008-06-02
    • Related Report
      2009 Final Research Report
  • [Presentation] Effects of compression timing on femoral blood flow during rhythmical calf compression synchronized to the cardiac cycle2008

    • Author(s)
      Nishiyasu T, Nakayama Y, Ichinose M.
    • Organizer
      ACSM
    • Place of Presentation
      Indianapolis, USA
    • Year and Date
      2008-05-30
    • Related Report
      2009 Final Research Report
  • [Presentation] Regulation of blood pressure and sympathetic nerve activity during exercise in humans-muscle metaboreflex and arterial baroreflex function-2007

    • Author(s)
      Nishiyasu T
    • Organizer
      University of Iowa
    • Place of Presentation
      Iowa City, USA
    • Year and Date
      2007-11-18
    • Related Report
      2009 Final Research Report
  • [Presentation] Regulation of blood pressure and sympathetic nerve activity during exercise in humans-muscle metaboreflex and arterial baroreflex function-2007

    • Author(s)
      Nishiyasu T
    • Organizer
      Wayne State University
    • Place of Presentation
      Detroit, USA
    • Year and Date
      2007-11-06
    • Related Report
      2009 Final Research Report
  • [Presentation] 暑熱下運動時における換気反応と体温調節反応や有酸素運動能力との関係2007

    • Author(s)
      林 恵嗣、本田 靖、小川 剛司、古賀 俊策、近藤 徳彦、西保 岳
    • Organizer
      第62回日本体力医学会
    • Place of Presentation
      秋田
    • Year and Date
      2007-09-15
    • Related Report
      2007 Annual Research Report
  • [Presentation] ヘッドアップチルト時における心拍および血流の調節-自発性変動に注目して-2007

    • Author(s)
      前田 良孝、一之瀬真志、西保 岳
    • Organizer
      第62回日本体力医学会
    • Place of Presentation
      秋田
    • Year and Date
      2007-09-15
    • Related Report
      2007 Annual Research Report
  • [Presentation] CO2吸入が暑熱下運動時における体温上昇に伴う換気反応や脳血流反応に及ぼす影響2007

    • Author(s)
      林 恵嗣、藤井直人、古賀俊策、近藤徳彦、西保 岳
    • Organizer
      第62回日本体力医学会
    • Place of Presentation
      秋田
    • Year and Date
      2007-09-15
    • Related Report
      2007 Annual Research Report
  • [Presentation] 安静時における深部体温上昇に伴う換気亢進と化学受容器換気調節及び脳血流の関係2007

    • Author(s)
      藤井直人、林 恵嗣、小川剛司、近藤徳彦、西保 岳
    • Organizer
      第62回日本体力医学会
    • Place of Presentation
      秋田
    • Year and Date
      2007-09-15
    • Related Report
      2007 Annual Research Report
  • [Presentation] 摂取する水温差が高温下運動中における循環・体温調節反応に及ぼす影響2007

    • Author(s)
      近藤徳彦、大上安奈、井上芳光、西保 岳
    • Organizer
      第62回日本体力医学会
    • Place of Presentation
      秋田
    • Year and Date
      2007-09-15
    • Related Report
      2007 Annual Research Report
  • [Presentation] 中程度の低圧下における短時間高強度インターバル走運動時の呼吸代謝応答2007

    • Author(s)
      小川剛司、藤井直人、西保 岳
    • Organizer
      第62回日本体力医学会
    • Place of Presentation
      秋田
    • Year and Date
      2007-09-15
    • Related Report
      2007 Annual Research Report
  • [Presentation] 高強度間欠的運動時におけるパワー発揮と有酸素・無酸素能力との関係性-上肢運動と下肢運動の比較-2007

    • Author(s)
      増田光治、小川剛司、藤井直人、西保 岳
    • Organizer
      第62回日本体力医学会
    • Place of Presentation
      秋田
    • Year and Date
      2007-09-15
    • Related Report
      2007 Annual Research Report
  • [Presentation] 高所環境が運動時及びトレーニング効果に及ぼす影響2007

    • Author(s)
      西保 岳
    • Organizer
      第58回日本体育学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2007-09-06
    • Related Report
      2007 Annual Research Report
  • [Presentation] 急性低圧下での換気機能が有酸素能力に及ぼす影響2007

    • Author(s)
      小川剛司、西保 岳
    • Organizer
      第58回日本体育学会大会運動生理分科会 シンポジウム
    • Place of Presentation
      神戸
    • Year and Date
      2007-09-06
    • Related Report
      2007 Annual Research Report
  • [Presentation] The effects of ventilation on VO2max in hypobaric hypoxia,2007

    • Author(s)
      Ogawa T, Nishiyasu T
    • Organizer
      1st Tsukuba-Detroit Scientific Symposium
    • Place of Presentation
      Detroit, USA
    • Year and Date
      2007-06-04
    • Related Report
      2007 Annual Research Report
  • [Presentation] Relatonship between aerobic, anaerobic capacity and power output during high intensity intermittent exercise-The case of Japanease rugby players-2007

    • Author(s)
      Masuda M, Nishiyasu T
    • Organizer
      1st Tsukuba-Detroit Scientific Symposium
    • Place of Presentation
      Detroit, USA
    • Year and Date
      2007-06-04
    • Related Report
      2007 Annual Research Report
  • [Presentation] The effect of the increase in body temperature on ventilation and cerebral blood flow2007

    • Author(s)
      Hayashi K, Nishiyasu T.
    • Organizer
      1st Tsukuba-Detroit Scientific Symposium
    • Place of Presentation
      Detroit, USA
    • Year and Date
      2007-06-04
    • Related Report
      2007 Annual Research Report
  • [Presentation] The effects of hydration status and heat acclimatization on hyperthermic hyperpnea2007

    • Author(s)
      Fujii N, Nishiyasu T.
    • Organizer
      1st Tsukuba-Detroit Scientific Symposium
    • Place of Presentation
      Detroit, USA
    • Year and Date
      2007-06-04
    • Related Report
      2007 Annual Research Report
  • [Presentation] Baroreflex control of muscle sympathetic nerve activity: Activated muscle metaboreflex in humans.2007

    • Author(s)
      Ichinose M, Nishiyasu T.
    • Organizer
      ACSM
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2007-06-01
    • Related Report
      2007 Annual Research Report
  • [Presentation] The effects of breathing Helium-oxygen mixture gas on VO2max in hypobaric hypoxia,2007

    • Author(s)
      Ogawa T, Calbet, JA, Hayashi K, Fujii N, Nishiyasu T
    • Organizer
      ACSM
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2007-06-01
    • Related Report
      2007 Annual Research Report
  • [Presentation] Relationship between ventilatory response and core temperatue at rest and during exercise2007

    • Author(s)
      Fujii N, Honda Y, Hayashi K, Soya H, Kondo N. and Nishiyasu T
    • Organizer
      ACSM
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2007-06-01
    • Related Report
      2007 Annual Research Report
  • [Book] 末梢(活動筋)反射や筋ポンプ作用による循環調節、循環II 運動時の調節と適応2007

    • Author(s)
      西保 岳
    • Total Pages
      10
    • Publisher
      ナップ
    • Related Report
      2007 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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