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Genetic nutrition research regarding osteoporosis risk modification and prevention in pubescent girls

Research Project

Project/Area Number 19300255
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Eating habits, studies on eating habits
Research InstitutionMukogawa Women's University

Principal Investigator

TAKII Yukio  Mukogawa Women's University, 生活環境学部, 教授 (70154937)

Co-Investigator(Kenkyū-buntansha) 山本 周美 (吉田 周美)  武庫川女子大学, 短期大学部, 講師 (60441234)
西村 沙矢香  武庫川女子大学, 生活環境学部, 助手 (00509177)
家森 幸男  武庫川女子大学, 国際健康開発研究所, 教授 (80025600)
森 真理  武庫川女子大学, 国際健康開発研究所, 研究員 (70399343)
Co-Investigator(Renkei-kenkyūsha) 相澤 徹  武庫川女子大学, 生活環境学部, 教授 (10340944)
Research Collaborator 菊川 薫  武庫川女子大学, 生活環境学部, 事務補佐
Project Period (FY) 2007 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥13,130,000 (Direct Cost: ¥10,100,000、Indirect Cost: ¥3,030,000)
Fiscal Year 2009: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2008: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2007: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Keywords遺伝栄養学 / 骨粗しょう症 / ストレス / 運動 / 思春期女子 / カルシウム摂取 / 爪遺伝子診断 / インフォームドコンセント / 遺伝子診断 / 食育 / メタボリックシンドローム / 思春期 / 骨密度 / 肥満度
Research Abstract

A significant correlation was observed between genotypes associated with osteogenesis and evaluation value for bone mass/body fat percentage in pubertal girls. Based on this fact, the following items were revealed : The interaction between genetic factors and living habits including dietary and fitness habits determines their somatotypes ; and bone mass after menopause depends on living habits. Women with a high bone mass value can develop osteoporosis if they have a negative lifestyle. On the other hand, somatic variants do not necessarily lead to osteoporosis. It is important to provide dietary education to adolescent girls based on the research outcome.

Report

(5 results)
  • 2010 Final Research Report ( PDF )
  • 2009 Annual Research Report   Self-evaluation Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (50 results)

All 2010 2009 2008 2007

All Journal Article (27 results) (of which Peer Reviewed: 27 results) Presentation (15 results) Book (5 results) Patent(Industrial Property Rights) (3 results)

  • [Journal Article] 若年女性の隠れ肥満を形成する食行動と遺伝的要因の検討2010

    • Author(s)
      西村沙矢香、宮林沙希、瀧井幸男
    • Journal Title

      日本食生活学会誌 17

      Pages: 227-230

    • NAID

      10027702930

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Efficient DNA extraction from nail clippings using the protease solution from Cucumis melo.2010

    • Author(s)
      S.Yamamoto, S.Nishimura, T.Okuno, M.Rakuman, Y.Takii
    • Journal Title

      Molecular Biotechnology 46

      Pages: 41-48

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of Aspergillus oryzae hydrolase family 43 xylosidase expressed in Escherichia coli.2010

    • Author(s)
      S.Suzuki, M.Fukuoka, H.Ookuchi, M.Sano, K.Ozeki, E.Nagayoshi, Y.Takii, M.Matsushita, S.Tada, K.Kusumoto, Y.Kashiwabara
    • Journal Title

      Journal of Bioscience and Bioengineering 109

      Pages: 115-117

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Efficient DNA extraction from nail clippings using the protease solution from Cucumis melo2010

    • Author(s)
      S. Yamamoto, Y. Takii, 4番目
    • Journal Title

      Molecular Biotechnology (in press)

    • Related Report
      2009 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Efficient DNA extraction from nail clippings using the protease solution from Cucumis melo.2010

    • Author(s)
      S.Yamamoto
    • Journal Title

      Molecular Biotechnology Epublish March 20(in press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 女子高校生のビタミンD受容体遺伝子多型に対する意識と食生活調査2009

    • Author(s)
      瀧井幸男、西村沙矢香
    • Journal Title

      日本食品化学会誌 16

      Pages: 163-173

    • NAID

      110007503399

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 米食と日本人の健康2009

    • Author(s)
      瀧井幸男
    • Journal Title

      FFI1ジャーナル 214

      Pages: 57-62

    • NAID

      40016462153

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] コメデンプンと日本人2009

    • Author(s)
      瀧井幸男
    • Journal Title

      食品・臨床栄養 5

      Pages: 45-50

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 女子高校生のビタミンD受容体遺伝子多型に対する意識と食生活調査2009

    • Author(s)
      瀧井幸男, 西村沙矢香
    • Journal Title

      日本食品化学学会誌 16巻

      Pages: 163-173

    • NAID

      110007503399

    • Related Report
      2009 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] 小学生野球選手における傷害発生に関する検討2009

    • Author(s)
      相澤徹, 下田麻友
    • Journal Title

      西宮医師会医学雑誌 14巻

      Pages: 39-43

    • Related Report
      2009 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] スポーツ傷害における情動的反応の傾向―性差に着目して―2009

    • Author(s)
      相澤徹, 伊達萬理子
    • Journal Title

      武庫川女子大学紀要 (人文・社会科学編) 57巻

      Pages: 109-125

    • NAID

      120005999308

    • Related Report
      2009 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] 女子高校生のビタミンD受容体遺伝子多型に対する意識と食生活調査2009

    • Author(s)
      瀧井幸男
    • Journal Title

      日本食品化学学会誌 16巻

      Pages: 163-173

    • NAID

      110007503399

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 米食と日本人の健康2009

    • Author(s)
      瀧井幸男
    • Journal Title

      FFIジャーナル 214

      Pages: 56-62

    • NAID

      40016462153

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 小学生野球選手における傷害発生に関する検討2009

    • Author(s)
      相澤徹
    • Journal Title

      西宮医師会医学雑誌 14

      Pages: 39-43

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] スポーツ傷害における情動的反応の傾向-性差に着目して-2009

    • Author(s)
      相澤徹
    • Journal Title

      武庫川女子大学紀要(人文・社会科学編) 57

      Pages: 109-125

    • NAID

      120005999308

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Efficient DNA extraction fromnail clippings using the protease solution from Cucumis melo.2009

    • Author(s)
      S. Yoshida-Yamamoto
    • Journal Title

      Molecular Biotechnology (in press)

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 米食と日本人の健康2009

    • Author(s)
      瀧井 幸男
    • Journal Title

      Foods & Food Ingredients Journal of Japan 214

      Pages: 56-62

    • NAID

      40016462153

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 体組成と脈波伝播速度からみた思春期女性の生活習慣病危険因子の検討2008

    • Author(s)
      相澤徹
    • Journal Title

      武庫川女子大学紀要(自然科学編) 56

      Pages: 1-6

    • NAID

      110008016743

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 思春期女性の踵骨骨評価値に対する利き足の影響に関する検討2008

    • Author(s)
      相澤徹, 他
    • Journal Title

      武庫川女子大学紀要(自然科学編) 56

      Pages: 7-14

    • NAID

      110008016745

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 若年女性の生活習慣と脂質代謝の関連に関する検討2008

    • Author(s)
      相澤徹, 他
    • Journal Title

      武庫川女子大学紀要(自然科学編) 56

      Pages: 15-22

    • NAID

      110008016747

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 大学女子学生の運動習慣が骨密度に及ぼす影響に関する検討2008

    • Author(s)
      相澤徹, 他
    • Journal Title

      武庫川女子大学紀要(自然科学編) 56

      Pages: 23-28

    • NAID

      110008016749

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 最近の成人麻疹感染症に関する一考察2008

    • Author(s)
      相澤徹, 他
    • Journal Title

      武庫川女子大学紀要(自然科学編) 56

      Pages: 29-32

    • NAID

      120005999672

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] GER合併の喘息で加療を受けていた症例に関する一考察2008

    • Author(s)
      相澤徹, 他
    • Journal Title

      武庫川女子大学紀要(自然科学編) 56

      Pages: 33-352

    • NAID

      120005999673

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 女子学生における体型、体質および食行動の意識調査2008

    • Author(s)
      瀧井 幸男
    • Journal Title

      食品・臨床栄養 4

      Pages: 3-10

    • NAID

      40017163149

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Calcium Tablets Reduce Osteoporosis Risk Factors and Increase Insulin-like Growth Factor-1 in High School Girls-A Randomized,Double-blind,Placebo-controlled Trials2007

    • Author(s)
      M Mori
    • Journal Title

      Clinical&Experimental Pharmacoiogy&Physiology 34

      Pages: 93-95

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Isoflavones as putative anti-aging food factors in Asia and effects of iso flavone aglycone-rich fermented soybeans on bone and glucose metabolicms in postmenopausal women2007

    • Author(s)
      M Mori
    • Journal Title

      Geriatrics and Gerontology International(GGI)supplement 7

      Pages: 8-15

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] New beverage for cardiovascular health,proposal based on oriental and occidental food culture from a world-wide epidemioloeical study2007

    • Author(s)
      Moriguchi, EH
    • Journal Title

      Geriatrics and Gerontology International(GGI)supelement 7

      Pages: 3-7

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] 抗菌性物質生産乳酸菌のスクリーニング2010

    • Author(s)
      西村沙矢香、川崎彩、小林知未、瀧井幸男
    • Organizer
      日本食品化学学会第16回大会
    • Place of Presentation
      大阪
    • Year and Date
      2010-06-09
    • Related Report
      2010 Final Research Report
  • [Presentation] 柿果皮由来キチナーゼ2010

    • Author(s)
      水田容子、矢野めぐむ、坂出裕子、辻本紗也佳、長池亜紀、西村沙矢香、瀧井幸男
    • Organizer
      日本食品化学学会第16回大会
    • Place of Presentation
      大阪
    • Year and Date
      2010-06-09
    • Related Report
      2010 Final Research Report
  • [Presentation] 未成年者飲酒予防の啓発2010

    • Author(s)
      小林玲香, 瀬川彩織、藤本寿々、西村沙矢香、瀧井幸男
    • Organizer
      日本食品化学学会16回大会
    • Place of Presentation
      大阪
    • Year and Date
      2010-06-09
    • Related Report
      2010 Final Research Report
  • [Presentation] 爪遺伝子診断法の紹介2010

    • Author(s)
      清重未来、楠田素子、栗花落美侑、藤本寿々、西村沙矢香、瀧井幸男
    • Organizer
      日本食品化学学会第16回大会
    • Place of Presentation
      大阪
    • Year and Date
      2010-06-09
    • Related Report
      2010 Final Research Report
  • [Presentation] 日本人とコメデンプン2009

    • Author(s)
      瀧井幸男
    • Organizer
      日本生物高分子学会
    • Place of Presentation
      京都府立大学
    • Year and Date
      2009-12-04
    • Related Report
      2009 Annual Research Report 2009 Self-evaluation Report
  • [Presentation] 爪遺伝子診断と若年女性の食育2008

    • Author(s)
      瀧井幸男
    • Organizer
      日本生物高分子学会2008年度大会
    • Place of Presentation
      亀岡
    • Year and Date
      2008-11-14
    • Related Report
      2010 Final Research Report
  • [Presentation] Genotype detection of alcoholism using fingernail DNA : Identifying a single nucleotide polymorphism in the aldehyde dehydrogenase 2 gene.2008

    • Author(s)
      瀧井幸男
    • Organizer
      13^<th> International SHR symposium in Prague
    • Place of Presentation
      Czech Republic
    • Year and Date
      2008-06-21
    • Related Report
      2010 Final Research Report
  • [Presentation] 爪DNAを用いるヒトALDH2遺伝子のSNP解析2008

    • Author(s)
      瀧井 幸男
    • Organizer
      第14回日本食品化学学会総会・学術大会
    • Place of Presentation
      武庫川女子大学
    • Year and Date
      2008-05-30
    • Related Report
      2008 Annual Research Report
  • [Presentation] メロン由来プロテアーゼを用いる効率的DNA抽出方法の確立2008

    • Author(s)
      西村 沙矢香
    • Organizer
      第14回日本食品化学学会総会・学術大会
    • Place of Presentation
      武庫川女子大学
    • Year and Date
      2008-05-30
    • Related Report
      2008 Annual Research Report
  • [Presentation] 遺伝子組換え麹菌によるグルコースの生産2007

    • Author(s)
      古市香、久保千佳、楽満美樹、吉田周美、藤井啓子、瀧井幸男
    • Organizer
      日本生物高分子学会2007年度大会
    • Place of Presentation
      下関
    • Year and Date
      2007-10-19
    • Related Report
      2010 Final Research Report
  • [Presentation] 若年女性の最大骨量規定する遺伝子多型の解析2007

    • Author(s)
      藤田幸、渡辺典子、薮本和美、吉田周美、瀧井幸男
    • Organizer
      日本生物高分子学会2007年度大会
    • Place of Presentation
      下関
    • Year and Date
      2007-10-19
    • Related Report
      2010 Final Research Report
  • [Presentation] 果実プロテアーゼによる爪ケラチンの分解2007

    • Author(s)
      楽満美樹、久保千佳、古市香、吉田周美、瀧井幸男
    • Organizer
      日本生物高分子学会2007年度大会
    • Place of Presentation
      下関
    • Year and Date
      2007-10-19
    • Related Report
      2010 Final Research Report
  • [Presentation] 若年女性の最大骨量を規定する遺伝子多型の解析2007

    • Author(s)
      瀧井 幸男
    • Organizer
      日本生物高分子学会
    • Place of Presentation
      下関市
    • Year and Date
      2007-10-19
    • Related Report
      2007 Annual Research Report
  • [Presentation] イソフラボンアグリコン高含有の無塩麹発酵大豆による骨代謝改善効果について2007

    • Author(s)
      家森 幸男
    • Organizer
      第61回日本栄養食糧学会大会
    • Place of Presentation
      京都市
    • Related Report
      2007 Annual Research Report
  • [Presentation] イソフラボンアグリコン高含有の無塩麹発酵大豆による骨密度及び脂質代謝敵善効果の検証2007

    • Author(s)
      家森 幸男
    • Organizer
      第54回日本栄養改善学会
    • Place of Presentation
      長崎市
    • Related Report
      2007 Annual Research Report
  • [Book] 改訂版「食の安全と健康」2009

    • Author(s)
      瀧井幸男
    • Total Pages
      130
    • Publisher
      わかくさ印刷
    • Related Report
      2010 Final Research Report 2009 Self-evaluation Report
  • [Book] 栄養学の最前線:第17章2009

    • Author(s)
      瀧井幸男、吉田周美
    • Publisher
      建帛社
    • Related Report
      2010 Final Research Report
  • [Book] スポーツ指導者のためのスポーツ医学 改訂第2版2009

    • Author(s)
      相澤徹
    • Total Pages
      320
    • Publisher
      南江堂
    • Related Report
      2010 Final Research Report 2009 Annual Research Report 2009 Self-evaluation Report
  • [Book] 栄養学研究の最前線2007

    • Author(s)
      瀧井 幸男
    • Total Pages
      202
    • Publisher
      建帛社
    • Related Report
      2007 Annual Research Report
  • [Book] 大豆イソフラボン〜生活習慣病予防栄養因子2007

    • Author(s)
      家森 幸男
    • Total Pages
      234
    • Publisher
      CMC出版
    • Related Report
      2007 Annual Research Report
  • [Patent(Industrial Property Rights)] 骨粗鬆症、骨形成不全症、又は骨密度形成不良症の発症リスクを診断する方法2010

    • Inventor(s)
      瀧井幸男、山本周美、西村沙矢香、南武士
    • Industrial Property Rights Holder
      瀧井幸男、山本周美、西村沙矢香、南武士
    • Patent Publication Number
      2010-246424
    • Filing Date
      2010-11-04
    • Related Report
      2010 Final Research Report
  • [Patent(Industrial Property Rights)] 骨粗鬆症、骨形成不全症、又は骨密度形成不良症の発症リスクを診断する方法2009

    • Inventor(s)
      瀧井幸男
    • Industrial Property Rights Holder
      瀧井幸男
    • Filing Date
      2009-04-13
    • Related Report
      2009 Self-evaluation Report
  • [Patent(Industrial Property Rights)] 特許権2009

    • Inventor(s)
      瀧井幸男
    • Industrial Property Rights Holder
      瀧井幸男
    • Filing Date
      2009-04-13
    • Related Report
      2009 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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