ISOTOPE RATIO MASS SPECTROMETRIC STUDY ON ISOTOPE RATIO ANALYSES OF AMINO ACIDS IN LIFE CYCLE ASSESSMENT FOR THIRTY YEARS FOOD EATINGS

• Project/Area Number: 19310025
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Environmental impact assessment/Environmental policy
• Research Institution: Tokyo Metropolitan University
• Principal Investigator: KORENAGA Takashi Tokyo Metropolitan University, 大学院・理工学研究科, 教授 (30124788)
• Co-Investigator(Kenkyū-buntansha): 松本 公平 首都大学東京, 理工学研究科, 客員研究員 (70359173)
• Project Period (FY): 2007 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥20,670,000 (Direct Cost: ¥15,900,000、Indirect Cost: ¥4,770,000); Fiscal Year 2009: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000); Fiscal Year 2008: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000); Fiscal Year 2007: ¥12,870,000 (Direct Cost: ¥9,900,000、Indirect Cost: ¥2,970,000)
• Keywords: 食環境変動 / 安定同位体比 / 質量分析 / アミノ酸 / 生体試料 / 安定同位体

Research Abstract

We discussed the dietary effect to the human body based on behavior of stable isotope ratio using amino acid in blood serum of the past 30 years. Stable isotope variation of each molecular amino acid clarified a influence of dietary change on human body and it impacted researches of the human life cycle.

Research Products

• [Journal Article] 農作物や肉・魚介類など農畜産物の産地や生産履歴を判別できる手法を開発 (2010)
  • Author(s): 伊永隆史, 後藤晶子, 島野淳子, 岡原功, 清水千明, 高見澤淳, 武蔵正明, 中下留美子, 鈴木彌生子
  • Journal Title: 農林水産技術研究ジャーナル Vol.33 No.3 Pages: 26-29
• [Journal Article] Application of Chromatography /Combustion/Isotope Ratio Mass Spectro metry for Stuying Nutrition and Biosyn thesis in Plants (2009)
  • Author(s): Mayu Yamamoto, Rumiko Nakashita, Yaeko Suzuki, Takahiro Ichimiya, Takashi Korenaga
  • Journal Title: Chemistry Letters Vol.38、No.7 Pages: 696-697
  • Peer Reviewed
• [Journal Article] 生元素安定同位体比解析による養殖ウナギの産地判別の可能性 (2009)
  • Author(s): 中下留美子, 鈴木彌生子, 一宮孝博, 伊永隆史
  • Journal Title: 日本食品科学工学会誌 Vol.56、No.9 Pages: 495-497
  • NAID: 10025582563
  • Peer Reviewed
• [Journal Article] 安定同位体比分析による日本国内に流通する牛肉の産地判別 (2009)
  • Author(s): 中下留美子, 鈴木彌生子, 伊永隆史渡辺伸枝, 田中公一
  • Journal Title: 分析化学 Vol.38 Pages: 1023-1028
  • NAID: 10025980664
  • Peer Reviewed
• [Journal Article] 安定同位体比分析による国産米の産地及び有機栽培判別の可能性 (2009)
  • Author(s): 鈴木彌生子, 中下留美子, 伊永隆史, 赤松史一, 伊永隆史
  • Journal Title: 分析化学 Vol.38 Pages: 1053-1058
  • NAID: 10025980747
  • Peer Reviewed
• [Journal Article] 安定同位体比分析によるウナギ加工品の産地判別の可能性 (2009)
  • Author(s): 伊永隆史
  • Journal Title: 分析化学 Vol.38 Pages: 1067-1070
  • NAID: 10025980818
  • Peer Reviewed
• [Journal Article] 安定同位体比の質量分析により食の安全を確保する (2009)
  • Author(s): 伊永隆史
  • Journal Title: Isotope News No.668 Pages: 2-7
  • NAID: 10026799945
• [Journal Article] 食品の産地偽装防止に用いられる安定同位体比質量分析装置とその利用価値 (2009)
  • Author(s): 伊永隆史
  • Journal Title: 食品機械装置 Vol.46 Nov. Pages: 57-66
• [Journal Article] 安定同位体の動態解析研究と食の安全における産地判別の応用 (2009)
  • Author(s): 伊永隆史
  • Journal Title: 臨床化学 Vol.38 Pages: 257-265
• [Journal Article] Application of Chromatography/Combustion/Isotope Ratio Mass Spectrometry for Studying Nutrition and Biosynthesis in Plants (2009)
  • Author(s): Mayu Yamamoto, Rumiko Nadashita, Yaeko Suzuki, Takahiro, Ichimiya, Takashi Korenaga
  • Journal Title: Chemistry Letters Vol.38 Pages: 696-697
  • Peer Reviewed
• [Journal Article] 生元素安定同位体比解析による養殖ウナギの産地判別の可能性 (2009)
  • Author(s): 中下留美子, 鈴木彌生子, 一宮孝博, 伊永隆史
  • Journal Title: 日本食品科学工学会誌 Vol.56 Pages: 495-497
  • NAID: 10025582563
  • Peer Reviewed
• [Journal Article] Application of stable isotope analysis to verify the authenticity of beef (2009)
  • Author(s): Takahiro Ichimiya, Rumiko Nakashita, Yaeko Suzuki, Fumikazu Akamatsu, Takasi Korenaga
  • Journal Title: The 4th International Symposium on Isotopomers (Proceedings) Pages: 279-284
• [Journal Article] High sensitive detection of 15N-labeled amino acids in crops by GC/IRMS (2009)
  • Author(s): Mayu Yamamoto, Yaeko Suzuki, Rumiko Nakasita, Takahiro Ichimiya, Fumikazu Akamatsu, Takasi Korenaga
  • Journal Title: The 4th International Symposium on Isotopomers (Proceedings) Pages: 274-278
• [Journal Article] Sta ble carbon, nitrogen, and oxygen isotope analysis as a potential tool for verifying geographical origin of beef (2008)
  • Author(s): Rumiko Nakashita, Yaeko Suzuki, Fumikazu Akamatsu, Yoshiko Iizumi, Taka Shi Korenaga, Yoshito Chikaraishi
  • Journal Title: Analytica Chimica Acta 618 Pages: 148-152
  • Peer Reviewed
• [Journal Article] Geographical origin of polished rice based on multiple element and stable isotope analyses (2008)
  • Author(s): Yaeko Suzuki, Yoshito Chikaraishi, Nanako Ogawa, Naohiko Ohkouchi, Takashi Korenaga
  • Journal Title: Food Chemistry 109 Pages: 470-475
  • Peer Reviewed
• [Journal Article] 安定同位体比解析による国産・豪州産・米国産牛肉の産地判別の可能性 (2008)
  • Author(s): 中下留美子, 鈴木彌生子, 赤松史一, 小原和仁, 伊永隆史
  • Journal Title: 日本食品科学工学会誌 Vol.55、No.4 Pages: 191-193
  • NAID: 10021178634
  • Peer Reviewed
• [Journal Article] 解説 食品の産地偽装を化学で暴く! --多元素安定同位体比の解析による産地判別技術 (2008)
  • Author(s): 伊永隆史, 鈴木彌生子, 中下留美子
  • Journal Title: 化学 63 Pages: 12-16
• [Journal Article] Geographical origin of polished rice based on multiple element and stable isotope analyses (2008)
  • Author(s): Yaeko Suzuki, Yoshito Chikaraishi, Nanako O. Ogawa, Naohiko Ohkouchi, and Takashi Korenaga
  • Journal Title: Food Chemistry 109 Pages: 470-475
  • Peer Reviewed
• [Journal Article] 安定同位体比解析による国産・豪州産・米国産牛肉の産地判別の可能性 (2008)
  • Author(s): 中下留美子, 鈴木彌生子, 赤松史一, 小原和仁, 伊永隆史
  • Journal Title: 日本食品科学工学会誌 55 Pages: 191-193
  • NAID: 10021178634
  • Peer Reviewed
• [Journal Article] 生元素安定同位体比解析によるコメの産地判別の可能性 (2008)
  • Author(s): 鈴木彌生子, 中下留美子, 赤松史一, 伊永隆史
  • Journal Title: 日本食品科学工学会誌 (In press)
  • Peer Reviewed
• [Journal Article] Stable carbon, nitrogen, and oxygen isotope analysis as a potential tool for verifying geographical origin of beef
  • Author(s): Rumiko Nakashita, Yaeko Suzuki, Fumikazu Akamatsu, Yoshiko Iizumi, Takashi Korenaga, Yoshito Chikaraishi
  • Journal Title: Analytica Chimica Acta (In press)
  • Peer Reviewed
• [Presentation] 安定同位体比精密測定による産地判別 (2010)
  • Author(s): 伊永隆史
  • Organizer: 中央農研セミナー
  • Place of Presentation: つくば
  • Year and Date: 2010-03-08
• [Presentation] 食品の産地を知る (2010)
  • Author(s): 伊永隆史
  • Organizer: 金沢大学薬学シンポジウム
  • Place of Presentation: 金沢
  • Year and Date: 2010-01-23
• [Presentation] 安定同位体を用いた食品の産地:判別・表示偽装防止技術の開発 (2009)
  • Author(s): 伊永隆史
  • Organizer: アグリビジネス創出フェア2009
  • Place of Presentation: 幕張
  • Year and Date: 2009-11-27
• [Presentation] 多変量解析による米のデータ解析と評価 (2009)
  • Author(s): 伊永隆史
  • Organizer: 表示・起源分析技術研究懇談会第2回講演会
  • Place of Presentation: つくば
  • Year and Date: 2009-11-17
• [Presentation] 食の安全を支える新技術 (2009)
  • Author(s): 伊永隆史
  • Organizer: 首都大学東京オープンユニバーシティ講演会
  • Place of Presentation: 東京
  • Year and Date: 2009-10-31
• [Presentation] 炭素、窒素安定同位体比分析によるヒト血清中アミノ酸と食料源の関係評価 (2009)
  • Author(s): 廣野留都, 武蔵正明, 中下留美子, 鈴木彌生子, 伊永隆史, 原田浩二, 小泉昭夫
  • Organizer: 日本地球化学会第56年会
  • Place of Presentation: 広島
  • Year and Date: 2009-09-15
• [Presentation] 窒素安定同位体比による15Nラベル化を用いた植物の窒素吸収・同化過程の窒素動態解析 (2009)
  • Author(s): 角田皓平, 山本真由, 武蔵正明, 中下留美子, 鈴木彌生子, 伊永隆史
  • Organizer: 日本地球化学会第56年会
  • Place of Presentation: 広島
  • Year and Date: 2009-09-15
• [Presentation] 炭素、窒素、酸素安定同位体比を用いた牛肉の産地推定の試み (2009)
  • Author(s): 後藤晶子, 高見澤淳, 武蔵正明, 中下留美子, 鈴木彌生子, 伊永隆史
  • Organizer: 日本地球化学会第56年会
  • Place of Presentation: 広島
  • Year and Date: 2009-09-15
• [Presentation] 軽元素の安定同位体比精密解析でわかること、わからないこと (2009)
  • Author(s): 伊永隆史
  • Organizer: JSTイノベーション・ジャパン2009
  • Place of Presentation: 東京
  • Year and Date: 2009-09-15
• [Presentation] 食の安全を守る科学トレーサビリティ (2009)
  • Author(s): 伊永隆史
  • Organizer: 日本食品工業倶楽部
  • Place of Presentation: 東京
  • Year and Date: 2009-08-25
• [Presentation] 安定同位体比質量分析法による食品の産地トレーサビリティ (2009)
  • Author(s): 伊永隆史
  • Organizer: 京都大学講演会
  • Place of Presentation: 京都
  • Year and Date: 2009-07-31
• [Presentation] 安定同位体元素で食品の産地や地球の歴史がわかる (2009)
  • Author(s): 伊永隆史
  • Organizer: JST産学公交流会
  • Place of Presentation: 東京
  • Year and Date: 2009-07-24
• [Presentation] 軽元素安定同位体比分析による産地判別技術の開発 (2009)
  • Author(s): 伊永隆史
  • Organizer: 日本食品工業倶楽部大阪支部
  • Place of Presentation: 大阪
  • Year and Date: 2009-07-14
• [Presentation] 安定同位体比解析による国産および輸入養殖ウナギの産地判別の可能性 (2009)
  • Author(s): 伊永隆史
  • Organizer: 第70回分析化学討論会
  • Place of Presentation: 和歌山
  • Year and Date: 2009-05-16
• [Presentation] 安定同位体比による産地特定と動態解析研究 (2009)
  • Author(s): 伊永隆史
  • Organizer: 第7回同位体科学研究会
  • Place of Presentation: 神奈川
  • Year and Date: 2009-03-06
• [Presentation] 安定同位体の動態解析研究と食の安全にかかる産地判別への応用 (2009)
  • Author(s): 伊永隆史
  • Organizer: 第57回質量分析総合討論会
  • Place of Presentation: 大阪
• [Presentation] ヒトの血清における炭素・窒素安定同位体比およびメチル水銀濃度と魚介類摂取量との関係. (2009)
  • Author(s): 中下留美子, 鈴木彌生子, 一宮孝博, 原田浩二, 小泉昭夫, 蜂谷紀之, 伊永隆史
  • Organizer: 第56回日本生態学会盛岡大会
  • Place of Presentation: 盛岡
• [Presentation] ^<15>Nトレーサー実験による生育中のイネのアミノ酸挙動の解析. (2009)
  • Author(s): 一宮孝博, 中下留美子, 鈴木彌生子, 佐々木由香, 伊永隆史
  • Organizer: 第56回日本生態学会盛岡大会
  • Place of Presentation: 盛岡
• [Presentation] Application of stable isotope analysis to verify the authenticity of beef. (2008)
  • Author(s): Takahiro Ichimiya, Rumiko Nakahsita, Yaeko Suzuki, Fumikazu Akamatsu, Takashi Korenaga
  • Organizer: The 4^<th> International Symposium on Isotopomers
  • Place of Presentation: Tokyo, Japan.
• [Presentation] High sensitive detection of ^<15>N-labeled amino acids in crops by GC/IRMS. (2008)
  • Author(s): Mayu Yamamoto, Yaeko Suzuki, Rumiko Nakashita, Takahiro Ichimiya, Fumikazu Aakamatsu, Takashi Korenaga
  • Organizer: The 4^<th> International Symposium on Isotopomers
  • Place of Presentation: Tokyo, Japan.
• [Presentation] A study on feeding habit of Asiatic black bear by nitrogen isotope analysis of amino acids. (2008)
  • Author(s): Rumiko Nakashita, Yaeko Suzuki, Fumikazu Akamatsu, Miho Sato, Mitsuaki Goto, Shigeyuki Izumiyama, Hidetake Hayashi, Muneoki Yoh, Toshio Tsubota, Takahiro Korenaga
  • Organizer: The 6th International Conference on Applications of Stable Isotope Techniques to Ecological Studies.
  • Place of Presentation: Hawaii, USA.
• [Presentation] Carbon, nitrogen, oxygen, and fatty acid hydrogen isotope analyses of polished rice for verifying its geographical origin. (2008)
  • Author(s): Rumiko Nakashita, Yaeko Suzuki, Fumikazu Akamatsu, Takashi Korenaga
  • Organizer: The 6th International Conference on Applications of Stable Isotope Techniques to Ecological Studies.
  • Place of Presentation: Hawaii, USA.
• [Presentation] Carbon and oxygen stable isotopes of rice as proxy parameters for changes in rice production with climate warming. (2008)
  • Author(s): Fumikazu Akamatsu, Yaeko Suzuki, Rumiko Nakashita, Takashi Korenaga
  • Organizer: The 6th International Conference on Applications of Stable Isotope Techniques to Ecological Studies.
  • Place of Presentation: Hawaii, USA.
• [Presentation] Geographical origin of beef based on bulk carbon, nitrogen, oxygen and fatty acid hydrogen isotope analyses. (2008)
  • Author(s): Yaeko Suzuki, Rumiko Nakashita, Fumikazu Akamatsu, Takashi Korenaga
  • Organizer: The 6th International Conference on Applications of Stable Isotope Techniques to Ecological Studies.
  • Place of Presentation: Hawaii, USA.
• [Presentation] アミノ酸分子の低濃度^<15>Nラベル化とそのガスクロマトグラフ/同位体比質量分析計(GC/IRMS)による検出. (2008)
  • Author(s): 山本真由, 鈴木彌生子, 中下留美子, 赤松史一, 伊永隆史
  • Organizer: 日本分析化学会第57年会
  • Place of Presentation: 福岡
• [Presentation] 炭素・窒素・酸素・水素安定同位体比を用いた牛肉の産地特定への可能性. (2008)
  • Author(s): 鈴木彌生子, 中下留美子, 赤松史一, 渡辺伸枝, 田中公一, 伊永隆史
  • Organizer: 日本食品科学工学会第55回大会
  • Place of Presentation: 京都
• [Presentation] 炭素・窒素・酸素安定同位体比による牛肉の産地判別の可能性. (2008)
  • Author(s): 中下留美子, 鈴木彌生子, 赤松史一, 伊永隆史
  • Organizer: 第69回分析化学討論会
  • Place of Presentation: 名古屋
• [Presentation] 脂肪酸の水素同位体比を用いた国産米の産地特定の可能性. (2008)
  • Author(s): 鈴木彌生子, 中下留美子, 赤松史一, 伊永隆史
  • Organizer: 第69回分析化学討論会
  • Place of Presentation: 名古屋
• [Presentation] C, N, and O stable isotope ratios as a tool to discriminate the beef origin (2007)
  • Author(s): Rumiko Nakashita, Yaeko Suzuki, Yoshiko Iizumi, Takashi Korenaga
  • Organizer: 3rd Interna tional symposium on Recent Advances in Food Analysis
  • Place of Presentation: チェコ
• [Presentation] Geographical origin of polished rice based on total organic carbon, nitrogen, oxygen and compound-specific hydrogen isotope analyses (2007)
  • Author(s): Yaeko Suzuki, Rumiko Nakashita, Takashi Korenaga
  • Organizer: 3rd International Symposium on Recent Advances in Food Analysis
  • Place of Presentation: チェコ
• [Presentation] C, N And O stable isotope ratios as A tool to discriminate the beef origin (2007)
  • Author(s): Rumiko Nakashita, Yaeko Suzuki, Yoshiko Iizumi, Takashi Korenaga
  • Organizer: 3rd International Symposium on Recent Advances in Food Analysis
  • Place of Presentation: チェコ
• [Presentation] 炭素・窒素同位体比分析によるコシヒカリの産地特定および有機農法判定の可能性 (2007)
  • Author(s): 鈴木彌生子・須藤理枝子・築山容子・伊永隆史
  • Organizer: 日本分析化学討論会第68年会
  • Place of Presentation: 宇都宮
• [Presentation] 多元素安定同位体比によるコシヒカリの産地特定および有機農法判定の可能性 (2007)
  • Author(s): 鈴木彌生子・中下留美子・須藤理枝子・築山容子・伊永隆史
  • Organizer: 日本食品科学工学会第54回大会
  • Place of Presentation: 福岡
• [Presentation] 炭素・窒素・酸素・水素安定同位体比によるコシヒカリの産地特定・有機農法判定の可能性 (2007)
  • Author(s): 鈴木彌生子・中下留美子・伊永隆史
  • Organizer: 第1回関東支部大会
  • Place of Presentation: 東京
• [Patent(Industrial Property Rights)] 農産物の産地判別方法、および養殖、輸入、天然ウナギ判別方法 (2009)
  • Inventor(s): 伊永隆史, 榮口彌生子, 中下留美子
  • Industrial Property Rights Holder: 伊永隆史
  • Industrial Property Number: 2009-062020
  • Filing Date: 2009-03-13
• [Patent(Industrial Property Rights)] バイオマス試料の由来判別方法およびコメの産地判別方法 (2009)
  • Inventor(s): 伊永隆史、鈴木彌生子、中下留美子
  • Industrial Property Rights Holder: 伊永隆史
  • Industrial Property Number: 2009-129075
  • Filing Date: 2009-05-28
• [Patent(Industrial Property Rights)] バイオマス試料の由来判別およびコメの産地判別方法 (2009)
  • Inventor(s): 伊永隆史, 鈴木彌生子, 中下留美子
  • Industrial Property Rights Holder: 伊永隆史
  • Industrial Property Number: 2009-129075
  • Filing Date: 2009-05-28