Exacerbation of airway diseases by wind-bone yellow dust contained with air pollutants, and it's epidemiological study in Japan
| Project/Area Number |
19310026
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Environmental impact assessment/Environmental policy
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| Research Institution | Oita University of Nursing and Health Sciences |
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Principal Investigator |
市瀬 孝道 Oita University of Nursing and Health Sciences, 看護学部, 教授 (50124334)
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| Co-Investigator(Kenkyū-buntansha) |
西川 雅高 国立環境研究所, 環境分析科学研究室, 室長 (80228171)
今井 透 東京慈恵会医科大学, 医学部, 准教授 (00130146)
吉田 成一 大分県立看護科学大学, 看護学部, 准教授 (40360060)
定金 香里 大分県立看護科学大学, 看護学部, 助教 (20322381)
岸川 禮子 国立病院機構, 福岡病院内科, アレルギー科医長 (50450945)
世良 暢之 福岡県保健環境研究所, 保健科学部, 専門研究員 (30446843)
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| Co-Investigator(Renkei-kenkyūsha) |
世良 暢之 , 福岡県保健環境研究所, 専門研究員 (30446843)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥20,020,000 (Direct Cost: ¥15,400,000、Indirect Cost: ¥4,620,000)
Fiscal Year 2009: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2008: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
Fiscal Year 2007: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
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| Keywords | 黄砂 / アレルギー / 疫学調査 / 花粉症 / 気管支喘息 / 動物モデル / 中国大都市PM10 / 飛来黄砂 / スギ花粉症 / アレルギー増悪 / マウスモデル / 鼻症状 / 眼症状 / β-グルカン / 微生物 / 変異原性 / 動物実験 |
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| Research Abstract |
The present study aims to evaluate the health impact, especially allergic respiratory diseases, caused by yellow dust through an epidemiological survey and animal experimental study. In the animal study, we demonstrated that airborne yellow dust aggravates allergic lung eosinophilia (asthma like symptom) induced by ovalbumin and the symptom in pollinosis induced by Japanese cider pollen. In the epidemiological survey in the South Kyushyu area, we demonstrated that yellow dust aggravates pollinosis and the ocular symptom.
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Report
(4 results)
Research Products
(21 results)
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[Journal Article] Urban particulate matter in Beijing, China enhances Allergen-Induced Murine Lung Eosinophilia2010
Author(s)
He M, Ichinose T, Yoshida S, Nishikawa M, Mori I, Yanagisawa R, Takano H, Inoue K, Sun G, Shibamoto T
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Journal Title
Inhal Toxicol. (In press)
Related Report
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[Journal Article] The effects of microbial materials adhered to Asian sand dust on allergic lung inflammation2008
Author(s)
Ichinose T, Yoshida S, Hiyoshi K, Sadakane K, Takano H, Nishikawa M, Mori I, Yanagisawa R, Kawazato H, Yasuda A, Shibamoto T.
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Journal Title
Arch Environ Contam Toxicol. 55(3)
Pages: 348-357
Related Report
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[Journal Article] Effects of asian sand dust, Arizona sand dust, amorphous silica and aluminum oxide on allergic inflammation in the murine lung.2008
Author(s)
Ichinose T, Yoshida S, Sadakane K, Takano H, Yanagisawa R, Inoue K, Nishikawa M, Mori I, Kawazato H, Yasuda A, Shibamoto T.
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Journal Title
Inhal Toxicol. 20(7)
Pages: 685-694
Related Report
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