| Budget Amount *help |
¥18,850,000 (Direct Cost: ¥14,500,000、Indirect Cost: ¥4,350,000)
Fiscal Year 2009: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2008: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2007: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
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| Research Abstract |
In our laboratory, we are interested in comprehensive natural products chemistry study based on search for bioactive small molecules from unexplored natural resources. We recently examined extracts of various natural resources including unexplored myxomycetes, marine organisms, as well as several medicinal plants collected in South Asia. Recently we are particularly interested in screening studies targeting TRAIL, Wnt, and Hedgehog signaling pathways which are related to cancer diseases. As a result of these screening programs we have isolated a number of new bioactive natural products and investigated their unique biological effects.
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