Psychophysiological studies on patience behavior
| Project/Area Number |
19330164
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Experimental psychology
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| Research Institution | Tokyo Metropolitan Organization for Medical Research |
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Principal Investigator |
WATANABE Masataka Tokyo Metropolitan Organization for Medical Research, 東京都神経科学総合研究所, 特任研究員 (50092383)
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| Co-Investigator(Kenkyū-buntansha) |
KODAMA Tohru 財団法人東京都医学研究機構, 東京都神経科学総合研究所, 副参事研究員 (20195746)
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| Co-Investigator(Renkei-kenkyūsha) |
HONNDA Yoshiko 財団法人東京都医学研究機構, 東京都神経科学総合研究所, 研究員 (50142154)
KOJIMA Takashi 財団法人東京都医学研究機構, 東京都神経科学総合研究所, 研究員 (30225429)
KUWAHATA Taku 財団法人東京都医学研究機構, 東京都神経科学総合研究所, 研究員 (70415537)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥18,720,000 (Direct Cost: ¥14,400,000、Indirect Cost: ¥4,320,000)
Fiscal Year 2009: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2008: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
Fiscal Year 2007: ¥7,930,000 (Direct Cost: ¥6,100,000、Indirect Cost: ¥1,830,000)
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| Keywords | がまん / サル / 前頭連合野 / ニューロン / 神経伝達物質 / セルフコントロール / リタリン / ADHD / ゴーノーゴー課題 |
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| Research Abstract |
Recently, both young and old people do not have enough patience. There are two kinds of patience ; one is to give up immediate small reward for later and much larger reward, and the other is to inhibit predominant response tendency to follow the social or moral rule. The prefrontal cortex plays important roles in the control of patience behavior. Primate prefrontal neurons show activity changes in relation to patience behavior. Methylphenidate (Ritalin) is known to control patience behavior in ADHD patients. Application of this drug to the monkey induced improvement in self-control behavior as well as inducing increase in dopamine release in the prefrontal cortex and striatum.
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Report
(4 results)
Research Products
(46 results)
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[Journal Article] Default mode of brain activity demonstrated by PET imaging in awake monkeys-higher rest-related than working memory-related activity in medial cortical areas.2009
Author(s)
Kojima, T., Onoe, H., Hikosaka, K., Tsutui, K-I., Tsukada, H., Watanabe, M.
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Journal Title
J. Neurosci. 29
Pages: 14463-14471
Related Report
Peer Reviewed
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[Journal Article] Default mode of brain activity demonstrated by PET imaging in a wake monkeys -higher rest-related than working memory-related activity in medial cortical areas2009
Author(s)
Kojima, T., Onoe, H., Hikosaka, K., Tsutsui, K., Tsukada, H., Watanabe, M
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Journal Title
Journal of Neuroscience 29
Pages: 14463-14471
Related Report
Peer Reviewed
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[Journal Article] Domain-related differentiation of working memory in the Japanese macaque (Macaca fuscata) frontal cortex: a positron emission tomography study2007
Author(s)
Kojima, T., Onoe, H., Hikosaka, K, Tsutsui, K, Tsukada, H, Watanabe, M.
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Journal Title
Eur. J. Neurosci. 25
Pages: 2523-2535
Related Report
Peer Reviewed
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[Presentation] Regions showing task-induced deactivation and regions with the highest level of regional cerebral blood flow during rest - A monkey PET study2009
Author(s)
Kojima, T., Onoe, H., Hikosaka, K., Tsutui, K-I., Tsukada, H., Watanabe, M.
Organizer
39th Society for Neuroscience Meeting
Place of Presentation
McCormic Convention Center, Chicago, USA
Year and Date
2009-10-21
Related Report
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[Presentation] Regions showing task-induced deactivation and regions with the highest level of regional cerebral blood flow during rest-A monkey PET study2009
Author(s)
Kojima, T., Onoe, H., Hikosaka, K., Tsutui, K-I., Tsukada, H., Watanabe, M.
Organizer
39th Society for Neuroscience Meeting
Place of Presentation
Chicago, USA
Year and Date
2009-10-21
Related Report
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