Mathematical Study of Pattern Formation and Information in Biological Systems

• Project/Area Number: 19340023
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: General mathematics (including Probability theory/Statistical mathematics)
• Research Institution: Hiroshima University
• Principal Investigator: KOBAYASHI Ryo Hiroshima University, 大学院・理学研究科, 教授 (60153657)
• Co-Investigator(Kenkyū-buntansha): NAKAGAKI Toshiyuki はこだて未来大学, システム情報工学部, 教授 (70300887) ; MIURA Takashi 京都大学, 大学院・医学研究科, 准教授 (10324617)
• Project Period (FY): 2007 – 2010
• Project Status: Completed (Fiscal Year 2010)
• Budget Amount: ¥18,330,000 (Direct Cost: ¥14,100,000、Indirect Cost: ¥4,230,000); Fiscal Year 2010: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000); Fiscal Year 2009: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000); Fiscal Year 2008: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000); Fiscal Year 2007: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
• Keywords: 真正粘菌変形体 / スタイナー問題 / ネットワーク / フェーズフィールド / 卵割 / アメーバ運動 / 数理モデル / 真正粘菌小形体 / 数理マデル / モルフォゲン / 血管網形成 / 細胞運動 / 自律分散制御 / 最短経路探索問題 / Physarum Solver / NP完全 / 中心体 / フェーズフィールドモデル

Research Abstract

We demonstrated experimentally that the plasmodium of Physarum polycephalum can promote formation of networks equivalent to the transportation network such as railroad system. We presented a new method of network design by constructing mathematical models. Also, we proposed models which describe how information works in the determining process of the geometry of early cleavage and in the formation of branching structure such as lung and blood vessel. We developed mathematical methods that can describe the mechanism combining biological pattern formation and information.

Research Products

• [Journal Article] Construction of seld-organized transportation networks in the polydomous Argentine ant, Journal of The Royal Society (2011)
  • Author(s): T.Latty, K.Pamsch, K.Ito, M.Middendorf, 中垣俊之, M.Beekman
  • Journal Title: Interface doi:10.1098/rsif. Volume: 8 Issue: 62 Pages: 0612-0612
  • DOI: 10.1098/rsif.2010.0612
  • Peer Reviewed
• [Journal Article] Mathematical model for contemplative amoeboid locomotion (2011)
  • Author(s): K.Ueda, S.Takagi, Y.Nishiura, 中垣俊之
  • Journal Title: Physical Review E 83 Pages: 2191-2191
  • Peer Reviewed
• [Journal Article] Mechanism of lung branching morphogenesis (2011)
  • Author(s): T.Miura
  • Journal Title: Biological and Physical Constraints on the Evolution of Form in Plants and Animals Volume: (In press)
  • Peer Reviewed
• [Journal Article] Mathematical model for contemplative amoeboid locomotion (2011)
  • Author(s): K.Ueda
  • Journal Title: Physical Review E Volume: 83 Pages: 2191-2191
  • Peer Reviewed
• [Journal Article] Construction of seld-organized transportation networks in the polydomous Argentine ant (2011)
  • Author(s): T.Latty
  • Journal Title: Journal of The Royal Society, Interface
  • Peer Reviewed
• [Journal Article] A Mathematical Model Of Cleavage (2010)
  • Author(s): M.Akiyama, A.Tero, 小林亮
  • Journal Title: J.Theor.Biol. 264(1) Pages: 84-94
  • Peer Reviewed
• [Journal Article] Risk management in spatio-temporally varying field by true slime mold (2010)
  • Author(s): K.Ito, D.Sumpter, 中垣俊之
  • Journal Title: Nonlinear Theory and Its Applications, IEICE Vol.1 Pages: 26-36
  • NAID: 130000908370
  • Peer Reviewed
• [Journal Article] Mathematical analysis to coupled oscillators system with a conservation law (2010)
  • Author(s): T.Miyaji, I.Ohnishi, 小林亮, A.Takamatsu
  • Journal Title: RIMS Kokyuroku Bessatsu B21 Pages: 129-147
  • Peer Reviewed
• [Journal Article] フェーズフィールド法のおもしろさ (2010)
  • Author(s): 小林亮
  • Journal Title: 計算工学 15(2) Pages: 2287-2290
  • NAID: 10026273440
• [Journal Article] Fully decentralized control of a soft-bodied robot inspired by true slime mold (2010)
  • Author(s): T.Umedachi, K.Takeda, 中垣俊之, 小林亮, A.Ishiguro
  • Journal Title: Biol.Cybern. 102 Pages: 261-269
  • Peer Reviewed
• [Journal Article] A method inspired by Physarum for solving the Steiner problem (2010)
  • Author(s): A.Tero, 中垣俊之, T.Kazutaka, Y.Kenji, 小林亮
  • Journal Title: International Journal of Unconventional Computing 6 Pages: 109-123
  • Peer Reviewed
• [Journal Article] Rules for biologically-inspired adaptive network design (2010)
  • Author(s): A.Tero, S.Takagi, T.Saigusa, K.Ito, D.P.Bebber, M.D.Fricker, K.Yumiki, 小林亮, 中垣俊之
  • Journal Title: Science 327 Pages: 439-442
  • NAID: 120002036686
  • Peer Reviewed
• [Journal Article] Reaction-Diffusion model as a Framework for Understanding Biological Pattern Formation (2010)
  • Author(s): S.Kondo, 三浦岳
  • Journal Title: Science 329 Pages: 1616-1620
  • Peer Reviewed
• [Journal Article] 反応拡散系の生物のパターン形成現象への応用 (2010)
  • Author(s): 三浦岳, 長山雅晴
  • Journal Title: 蛋白質核酸酵素 55(1) Pages: 114-122
• [Journal Article] Reaction-Diffusion model as a Framework for Understanding Biological Pattern Formation (2010)
  • Author(s): S.Kondo
  • Journal Title: Science Volume: 329 Pages: 1616-1620
  • Peer Reviewed
• [Journal Article] Risk management in spatio-temporally varying field by true slime mold (2010)
  • Author(s): K.Ito
  • Journal Title: NOLTA (Nonlinear Theory and Application) journal, IEICE Volume: 1 Pages: 26-36
  • Peer Reviewed
• [Journal Article] Mathematical analysis to coupled oscillators system with a conservation law (2010)
  • Author(s): T.Miyaji
  • Journal Title: RIMS Kokyuroku Bessatsu Volume: B21 Pages: 129-147
  • Peer Reviewed
• [Journal Article] A Mathematical Model Of Cleavage (2010)
  • Author(s): M. Akiyama, A. Tero, R. Kobayashi
  • Journal Title: J.Theor.Biol. 264(1) Pages: 84-94
  • Peer Reviewed
• [Journal Article] Fully decentralized control of a soft-bodied robot inspired by true slime mold (2010)
  • Author(s): T. Umedachi, K. Takeda, T. Nakagaki, R. Kobayashi, A. Ishiguro
  • Journal Title: Biol.Cybern. 102 Pages: 261-269
  • Peer Reviewed
• [Journal Article] Rules for biologically-inspired adaptive network design (2010)
  • Author(s): A. Tero, S. Takagi, T. Saigusa, K. Ito, D. P. Bebber, M. D. Fricker, K. Yumiki, R. Kobayashi, T. Nakagaki
  • Journal Title: Science 327 Pages: 439-442
  • NAID: 120002036686
  • Peer Reviewed
• [Journal Article] Rules for biologically-inspired adaptive network design (2010)
  • Author(s): A.Tero
  • Journal Title: Science 327 Pages: 439-442
  • Peer Reviewed
• [Journal Article] A method inspired by Physarum for solving the Steiner problem (2010)
  • Author(s): A.Tero
  • Journal Title: International Journal of Unconventional Computing 6 Pages: 109-123
  • Peer Reviewed
• [Journal Article] A Mathematical Model of Cleavage (2010)
  • Author(s): M.Akiyama
  • Journal Title: J.Theor.Biol. (in press)
  • Peer Reviewed
• [Journal Article] Mechanism of skull suture maintenance and interdigitation (2009)
  • Author(s): 三浦岳, C.A.Perlyn, M.Kinboshi, N.Ogihara, M.Kobayashi-Miura G.M.Morriss-Kay, K.Shiota
  • Journal Title: J.Anat. 215 Pages: 642-655
  • Peer Reviewed
• [Journal Article] In vitro vasculogenesis models revisited - Measurement of VEGF's diffusion in Matrigel. (2009)
  • Author(s): 三浦岳, R.Tanaka
  • Journal Title: Mathematical Modelling of Natural Phenomena 4(4) Pages: 118-130
  • Peer Reviewed
• [Journal Article] Computational ability of cells based on dynamics and adaptability (2009)
  • Author(s): 中垣俊之, A.Tero, 小林亮, I.Onishi, T.Miyaji
  • Journal Title: New Generation Computing, Ohmsha-Springer 27(1) Pages: 57-81
• [Journal Article] The cyst-branch difference in developing chick lung results from a different morphogen diffusion coefficient (2009)
  • Author(s): 三浦岳, D.Hartman, M.Kinboshi, M.Komada, M.Ishibashi, K.Shiota
  • Journal Title: Mechanisms of Development 126 Pages: 160-172
  • Peer Reviewed
• [Journal Article] Mechanism of skull suture maintenance and interdigitation (2009)
  • Author(s): T.Miura
  • Journal Title: J.Anat. 215 Pages: 642-655
  • Peer Reviewed
• [Journal Article] In vitro vasculogenesis model revisited -Measurement of VEGF diffusion in Matrigel (2009)
  • Author(s): T.Miura
  • Journal Title: Mathematical Modelling of Natural Phenomena 55 Pages: 118-130
  • Peer Reviewed
• [Journal Article] A method inspired by Physarum for solving the Steiner problem (2009)
  • Author(s): A. Tero
  • Journal Title: International Journal of Unconventional Computing (To be published)
  • Peer Reviewed
• [Journal Article] Computational ability of cells based on dynamics and adaptability (2009)
  • Author(s): T. Nakagaki
  • Journal Title: New Generation Computing 27 Pages: 57-81
  • Peer Reviewed
• [Journal Article] The cyst-branch difference in developing chick lung results from a different morphogen diffusion coefficient (2009)
  • Author(s): T. Miura
  • Journal Title: Aechanisms of Development 126 Pages: 160-172
  • Peer Reviewed
• [Journal Article] Flow-network adaptation in Physarum amoebae (2008)
  • Author(s): A.Tero, K.Yumiki, 小林亮, T.Saigusa, 中垣俊之
  • Journal Title: Theory In Biosciences 127 Pages: 89-94
  • NAID: 120001336280
  • Peer Reviewed
• [Journal Article] Hedgehog signaling is involved in development of the neocortex (2008)
  • Author(s): M.Komada, H.Saitsu, M.Kinboshi, 三浦岳, K.Ishibashi, K.Shiota
  • Journal Title: Development 135 Pages: 2717-2727
  • Peer Reviewed
• [Journal Article] Flow-network adaptation in Physarum amoebae (2008)
  • Author(s): A. Tero
  • Journal Title: Theory In Biosciences 127 Pages: 89-94
  • Peer Reviewed
• [Journal Article] Hedgehog signaling is involved in development of the neocortex. (2008)
  • Author(s): M. Komada
  • Journal Title: Development 135 Pages: 2717-2727
  • Peer Reviewed
• [Journal Article] A mathematical model for adaptive transport network in path finding by the true slime mold (2007)
  • Author(s): A.Tero, 小林亮, 中垣俊之
  • Journal Title: J.Theor.Biol. 244 Pages: 553-564
  • NAID: 120000875271
  • Peer Reviewed
• [Journal Article] Effects of food amount on path selection in transport network of an amoeboid organism (2007)
  • Author(s): 中垣俊之, T.Saigusa, A.Tero, 小林亮
  • Journal Title: Topological Aspects of Critical Systems and Networks, World Scientific Pages: 94-100
  • Peer Reviewed
• [Journal Article] Minimum-risk path finding by an adaptive amoebal network (2007)
  • Author(s): 中垣俊之, M.Iima, T.Ueda, Y.Nishiura,T.Saigusa, A.Tero, 小林亮, K.Showalter
  • Journal Title: Phys.Rev.Lett. 99 Pages: 68104-68104
  • Peer Reviewed
• [Journal Article] アメーバに学ぶ経路探索の方法 (2007)
  • Author(s): 手老篤史、中垣俊之、小林亮
  • Journal Title: Materials Integration 20(5) Pages: 55-60
• [Journal Article] 粘菌による迷路の解法 (2007)
  • Author(s): 小林亮、手老篤史、中垣俊之
  • Journal Title: 細胞工学 26(7) Pages: 769-773
• [Journal Article] Minimum-risk path finding by an adaptive amoebal network (2007)
  • Author(s): T. Nakagaki, M. Iima, T. Ueda, Y. Nishiura, T. Saigusa, A. Tero, R. Kobayashi, K. Showalter
  • Journal Title: Phys.Rev.Lett. 99 Pages: 68104-68104
  • Peer Reviewed
• [Journal Article] A mathematical model for adaptive transport network in path finding by the true slime mold (2007)
  • Author(s): A. Tero, R. Kobayashi, T. Nakagaki
  • Journal Title: J.Theor.Biol. 244 Pages: 553-564
  • NAID: 120000875271
  • Peer Reviewed
• [Journal Article] Minimum-risk path finding by an adaptive amoebal network (2007)
  • Author(s): T. Nakagaki
  • Journal Title: Phys. Rev. Lett. 99 Pages: 68104-68104
  • Peer Reviewed
• [Journal Article] 粘菌による迷路の解法 (2007)
  • Author(s): 小林 亮
  • Journal Title: 細胞工学 26 Pages: 769-773
• [Journal Article] Effects of food amount on path selection in transport network of an amoeboid organism (2007)
  • Author(s): T. Nakagaki
  • Journal Title: Topological Aspects of Critical Systems and Networks (Proceedings of the international conference on Topological Aspects of Critical Systems and networks) Pages: 94-100
  • Peer Reviewed
• [Journal Article] Mechanism of lung branching morphogenesis, Biological and Physical Constraints on the Evolution of Form in Plants and Animals
  • Author(s): 三浦岳
  • Journal Title: Vienna series in Theoretical biology in press
  • Peer Reviewed
• [Presentation] Toward Understanding the Locomotion of Animals (2011)
  • Author(s): 小林亮
  • Organizer: International Workshop on Far-From-Equilibrium Dynamics
  • Place of Presentation: Kyoto
  • Year and Date: 2011-01-04
• [Presentation] Mathematical Modeling of Crawling Animals (2010)
  • Author(s): 小林亮
  • Organizer: 9th iCeMS International Symposium "Mesoscale Control and Engineering of Self-Organized and Excitable Systems in Biology and Chemistry"
  • Place of Presentation: Kyoto
  • Year and Date: 2010-12-03
• [Presentation] Mathematical Modeling of Crawling Animals (2010)
  • Author(s): R.Kobayashi
  • Organizer: 9th iCeMS International Symposium"Mesoscale Control and Engineering of Self-Organized and Excitable Systems in Biology and Chemistry"
  • Place of Presentation: Kyoto(招待講演)
  • Year and Date: 2010-12-03
• [Presentation] Ethology of an amoeba-physiology and mathematical modeling (2010)
  • Author(s): 中垣俊之
  • Organizer: Lecture in GCOE program Industrial Mathematics, Meiji University
  • Place of Presentation: Tokyo
  • Year and Date: 2010-10-25
• [Presentation] Ethology of an amoeba-physiology and mathematical modeling- (2010)
  • Author(s): T.Nakagaki
  • Organizer: Lecture in GCOE program Industrial Mathematics
  • Place of Presentation: Meiji University, Tokyo(招待講演)
  • Year and Date: 2010-10-25
• [Presentation] Mechanisim of lung branching morphogenesis (2010)
  • Author(s): 三浦岳
  • Organizer: 34^<th> Altenberg Workshop in Theoretical Biology
  • Place of Presentation: Vienna, Austria
  • Year and Date: 2010-09-26
• [Presentation] Mechanism of lung branching morphogenesis (2010)
  • Author(s): T.Miura
  • Organizer: 24th ALTENBERG WORKSHOP IN THEORETICAL BIOLOGY
  • Place of Presentation: Vienna, Austria(招待講演)
  • Year and Date: 2010-09-26
• [Presentation] Mathematical Modeling of the Locomotion of Amoeba (2010)
  • Author(s): 小林亮
  • Organizer: Czech-Japan Seminar in Applied Mathematics
  • Place of Presentation: Prague, Telc, Czech
  • Year and Date: 2010-08-31
• [Presentation] Mathematical Modeling of the Locomotion of Amoeba (2010)
  • Author(s): R.Kobayashi
  • Organizer: Czech-Japan Seminar in Applied Mathematics
  • Place of Presentation: Prague, Czech(招待講演)
  • Year and Date: 2010-08-31
• [Presentation] Mathematical Modeling for Pattern Formation in Nature (2010)
  • Author(s): 小林亮
  • Organizer: ISSCG-14
  • Place of Presentation: Dalian, China
  • Year and Date: 2010-08-04
• [Presentation] Mathematical Modeling for Pattern Formation in Nature (2010)
  • Author(s): R.Kobayashi
  • Organizer: ISSCG-14
  • Place of Presentation: Dalian, China(招待講演)
  • Year and Date: 2010-08-04
• [Presentation] 真正粘菌の知性-細胞のエソロジカルダイナミクス- (2010)
  • Author(s): 小林亮、中垣俊之、手老篤史
  • Organizer: 理研ASI細胞システムコロキウムシリーズI「理論生物学」
  • Place of Presentation: 和光市
  • Year and Date: 2010-06-04
• [Presentation] Ethological Dynamics of True Slime Mold (2010)
  • Author(s): 中垣俊之、小林亮
  • Organizer: 理研ASI細胞システムコロキウムシリーズI「理論生物学」
  • Place of Presentation: 和光市
  • Year and Date: 2010-06-04
• [Presentation] 真正粘菌の知性-細胞のエソロジカルダイナミクス- (2010)
  • Author(s): 小林亮
  • Organizer: 理論生物学(理研ASI細胞システムコロキウムシリーズI)
  • Place of Presentation: 理研、和光(招待講演)
  • Year and Date: 2010-06-04
• [Presentation] 真正粘菌の知性 (2010)
  • Author(s): 中垣俊之
  • Organizer: 理論生物学(理研ASI細胞システムコロキウムシリーズI)
  • Place of Presentation: 理研、和光(招待講演)
  • Year and Date: 2010-06-04
• [Presentation] Mechamism of lung branching morphogenesis (2010)
  • Author(s): 三浦岳
  • Organizer: 日本生理学会みちのくシンポジウム
  • Place of Presentation: 盛岡
  • Year and Date: 2010-05-19
• [Presentation] Mechanism of lung branching morphogenesis (2010)
  • Author(s): 三浦岳
  • Organizer: 日本生理学会みちのくシンポジウム
  • Place of Presentation: 盛岡(招待講演)
  • Year and Date: 2010-05-19
• [Presentation] Ethology of plasmodial amoeba of slime mold in relation to the capacity of information processing in cell (2010)
  • Author(s): 中垣俊之
  • Organizer: 2^<nd> GCOE International Symposium of Animal Global Health. Special lecture
  • Place of Presentation: Obihiro University of Agriculture and Veterinary Medicine
  • Year and Date: 2010-04-04
• [Presentation] Ethology of plasmodial amoeba of slime mold in relation to the capacity of information processing in cell (2010)
  • Author(s): T.Nakagaki
  • Organizer: 2^<nd> GCOE International Symposium of Animal Global Health.
  • Place of Presentation: Obihiro University of Agriculture and Veterinary Medicine(Special lecture 招待講演)
  • Year and Date: 2010-04-04
• [Presentation] Ethology of amoeba viewed from nonlinear dynamics (2010)
  • Author(s): 中垣俊之
  • Organizer: La 13e Rencontre du Non-lineaire, nstitut Henri Poincare
  • Place of Presentation: France
  • Year and Date: 2010-03-15
• [Presentation] Ethology of amoeba viewed from nonlinear dynamics (2010)
  • Author(s): T.Nakagaki
  • Organizer: La 13e Rencontre du Non-lineaire
  • Place of Presentation: Institut Henri Poincare, France
  • Year and Date: 2010-03-15
• [Presentation] 血管網形成の数理モデル (2009)
  • Author(s): 小林亮
  • Organizer: 京都大学再生医科学研究所平成21年度学術講演会
  • Place of Presentation: 京都大学
  • Year and Date: 2009-12-14
• [Presentation] 自発的パターン形成における拡散と領域成長の役割:培養系での形態制御の可能性 (2009)
  • Author(s): 三浦岳
  • Organizer: 日本バイオマテリアル学会
  • Place of Presentation: 京都
  • Year and Date: 2009-11-17
• [Presentation] フェーズフィールドモデルのおもしろさ (2009)
  • Author(s): 小林亮
  • Organizer: 日本機械学会第22回計算力学講演会
  • Place of Presentation: 金沢大学
  • Year and Date: 2009-10-10
• [Presentation] Modeling Lung Branching Morphogenesis", EMBO Conference Series on Morphogenesis and Dynamics of Multicellular Systems (2009)
  • Author(s): 三浦岳
  • Organizer: EMBO Conference Series on Morphogenesis and Dynamics of Multicellular Systems
  • Place of Presentation: Heidelberg, Germany
  • Year and Date: 2009-10-03
• [Presentation] Negotiating multi-purpose optimization problem by means of the adaptive method inspired by a single celled organism Physarum (2009)
  • Author(s): A.Tero, M.Yamaguchi, 小林亮, 中垣俊之
  • Organizer: 4th International Workshop on Natural Computing
  • Place of Presentation: Himeji
  • Year and Date: 2009-09-23
• [Presentation] Negotiating multipurpose optimization problem by means of the adaptive method inspired by a single celled organism Physarum (2009)
  • Author(s): A.Tero
  • Organizer: 4th International Workshop on Natural Computing
  • Place of Presentation: Himeji
  • Year and Date: 2009-09-23
• [Presentation] 真性粘菌変形体から探る自律分散制御のからくりと大自由度ロボット制御への応用 (2009)
  • Author(s): 石黒章夫、梅舘拓也、武田光一、中垣俊之、小林亮
  • Organizer: 第19回日本数理生物学会
  • Place of Presentation: 東京大学
  • Year and Date: 2009-09-10
• [Presentation] 卵割の数理モデル (2009)
  • Author(s): 秋山正和、手老篤史、小林亮
  • Organizer: 第19回日本数理生物学会
  • Place of Presentation: 東京大学
  • Year and Date: 2009-09-10
• [Presentation] Innovations in controlling hyper-redundant and flexible systems inspired by biological locomotion (2009)
  • Author(s): 小林亮
  • Organizer: 明治大学広島大学グローバルCOE「現象数理学の形成と発展」広島キックオフフォーラム
  • Place of Presentation: 広島大学
  • Year and Date: 2009-09-03
• [Presentation] A Mathematical Model of Amoeboid Locomotion (2009)
  • Author(s): 小林亮
  • Organizer: Reaction-Diffusion Systems : Modeling and Analysis, Universite de Paris-Sud 11
  • Place of Presentation: Orsay, France
  • Year and Date: 2009-06-04
• [Presentation] A Mathematical Model of Amoeboid Locomotion (2009)
  • Author(s): 小林亮
  • Organizer: Reaction-Diffusion Systems : Modeling and Analysis
  • Place of Presentation: Universite de Paris-Sud11, France
  • Year and Date: 2009-06-02
• [Presentation] Biologistics learned from adaptable transport network of food locations in slime mold (2009)
  • Author(s): 中垣俊之, 小林亮, A.Tero
  • Organizer: The 2nd Ladenburger Kolleg meeting on "From Bio-inspired Logistics to Logistics-Inspired Bio-Nano-Engineering"
  • Place of Presentation: Berlin, Germany
  • Year and Date: 2009-04-20
• [Presentation] A Mathematical Model of Amoeboid Locomotion (2009)
  • Author(s): 小林亮
  • Organizer: International Conference for Nonlinear Science, Sapporo Winter School
  • Place of Presentation: Hokkaido University
  • Year and Date: 2009-02-10
• [Presentation] A Mathematical Model of Amoeboid Locomotion (2009)
  • Author(s): R. Kobayashi
  • Organizer: International Conference for Nonlinear Science, Sapporo Winter School
  • Place of Presentation: Sapporo
  • Year and Date: 2009-02-10
• [Presentation] アメーバ運動の数理モデル (2009)
  • Author(s): 小林亮
  • Organizer: 生命数理セミナー研究会
  • Place of Presentation: 北海道虻田郡
  • Year and Date: 2009-01-19
• [Presentation] アメーバ運動の数理モデル (2008)
  • Author(s): 小林亮
  • Organizer: 第46回日本生物物理学会年会
  • Place of Presentation: 福岡国際会議場
  • Year and Date: 2008-12-03
• [Presentation] アメーバ運動の数理モデル (2008)
  • Author(s): 小林 亮
  • Organizer: Dynamics Days Asia Pacific 5
  • Place of Presentation: 福岡
  • Year and Date: 2008-12-03
• [Presentation] アメーバ運動の数理モデル (2008)
  • Author(s): 小林亮
  • Organizer: 日本機械学会第21回計算力学講演会CMD2008
  • Place of Presentation: 琉球大学
  • Year and Date: 2008-11-02
• [Presentation] A Mathematical Model of Amoeboid Locomotion (2008)
  • Author(s): 小林亮
  • Organizer: Mathematical Understanding of Complex Systems arising in Biology and Medicine
  • Place of Presentation: Meiji University
  • Year and Date: 2008-10-28
• [Presentation] A Mathematical Model of Amoeboid Locomotion (2008)
  • Author(s): R. Kobayashi
  • Organizer: Mathematical Understanding of Complex Systemsarising in Biology and Medicine
  • Place of Presentation: Tokyo
  • Year and Date: 2008-10-28
• [Presentation] A Mathematical Model of Amoeboid Locomotion (2008)
  • Author(s): 小林亮
  • Organizer: 第18回日本数理生物学会大会
  • Place of Presentation: 京都
  • Year and Date: 2008-09-17
• [Presentation] A Mathematical Model of Amoeboid Locomotion (2008)
  • Author(s): 小林亮
  • Organizer: Dynamics Days Asia Pacific 5
  • Place of Presentation: Nara
  • Year and Date: 2008-09-11
• [Presentation] Patterns and Computations in BiologicalSystems-True Slime Mold- (2008)
  • Author(s): 小林亮, A.Tero, 中垣俊之
  • Organizer: Czech-Japanese Seminar in Applied Mathematics 2008
  • Place of Presentation: Takachiho, Miyazaki
  • Year and Date: 2008-09-02
• [Presentation] Patterns and Computations in Biological Systems -- True Slime Mold -- (2008)
  • Author(s): R. Kobayashi
  • Organizer: Czech-Japanese Seminar in Applied Mathematics 2008
  • Place of Presentation: Takachiho
  • Year and Date: 2008-09-01
• [Presentation] A Mathematical Model of Locomoting Amoeba (2008)
  • Author(s): 小林亮
  • Organizer: The Second China-Japan Colloquium of Mathematical Biology
  • Place of Presentation: Okayama
  • Year and Date: 2008-08-05
• [Presentation] Organic Computing by an amoeba : Optimization in natural systems (2008)
  • Author(s): 中垣俊之, A.Tero, 小林亮, D.Sumpter, M.Beekman, M.Middendorf
  • Organizer: The 9th Human frontier science program awardee meeting, Berlin Brandenburg Academy of Sciences and Humanities
  • Place of Presentation: Germany
  • Year and Date: 2008-07-24
• [Presentation] A Mathematical Model of Locomoting Amoeba (2008)
  • Author(s): 小林亮
  • Organizer: European Conference on Mathematical and Theoretical Biology
  • Place of Presentation: Edinburgh, UK
  • Year and Date: 2008-07-03
• [Presentation] A Mathematical Model of Amoeboid Locomotion (2008)
  • Author(s): 小林亮
  • Organizer: Gordon Research Conference on Mathematical Biology and Biomathematics
  • Place of Presentation: Barga, Italy
  • Year and Date: 2008-06-22
• [Presentation] A Mathematical Model of Amoeboid Locomotion (2008)
  • Author(s): R. Kobayashi
  • Organizer: Gordon Research Conference on Mathematical Biology and Biomathematics
  • Place of Presentation: Barga, Itaria
  • Year and Date: 2008-06-22
• [Presentation] A Mathematical Model of Locomoting Amoeba (2008)
  • Author(s): R. Kobayashi
  • Organizer: European Conference on Mathematical and Theoretical Biology
  • Place of Presentation: Edinburgh, Scotland
  • Year and Date: 2008-06-04
• [Presentation] アメーバの賢さのしくみと制御 (2008)
  • Author(s): 中垣俊之、手老篤史、三枝徹、小林亮
  • Organizer: 第52回システム制御情報学会研究発表会
  • Place of Presentation: 京都情報大学院大学京都駅前校
  • Year and Date: 2008-05-17
• [Presentation] Information processing at cell level -smart behaviors in an amoeba of Physarum- (2008)
  • Author(s): 中垣俊之, A.Tero, 三枝徹, 小林亮
  • Organizer: Korean Physical Society Meeting
  • Place of Presentation: Dejeon, Korea
  • Year and Date: 2008-04-08
• [Presentation] Functional networking by an amoeba (2008)
  • Author(s): 中垣俊之, A.Tero, 三枝徹, 小林亮
  • Organizer: NSC Winter Workshop 2008 : Complex Nonlinear Dynamics ranging from Biology to Engineering
  • Place of Presentation: Hokkaido Univrsity
  • Year and Date: 2008-03-08
• [Presentation] 粘菌ネットワークの流量適応ダイナミクス (2007)
  • Author(s): 中垣俊之、手老篤史、小林亮
  • Organizer: 第13回交通流のシミュレーションシンポジウム
  • Place of Presentation: 名古屋大学
  • Year and Date: 2007-12-07
• [Presentation] A Biologically Motivated Shortest Path Finding Problem (2007)
  • Author(s): 小林亮、弓木健嗣、手老篤史、中垣俊之
  • Organizer: 数理解析研究所研究集会
  • Place of Presentation: 京都
  • Year and Date: 2007-11-15
• [Presentation] 生物の賢さを生み出す情報処理のしくみーアメーバの事例からー (2007)
  • Author(s): 中垣俊之、手老篤史、三枝徹、小林亮
  • Organizer: 北海道大学創成科学シンポジウム
  • Place of Presentation: 北海道大学
  • Year and Date: 2007-11-02
• [Presentation] Dynamical Synchronization in True Slime Mold-Maze Solving Amoeba- (2007)
  • Author(s): 小林亮, A.Tero, 中垣俊之
  • Organizer: The 23rd Symposium of the Society of Population Ecology "Spatial Structure and Dynamics of Ecological System"
  • Place of Presentation: Sapporo
  • Year and Date: 2007-10-19
• [Presentation] Dynamical Synchronization in True Slime Mold -Maze Solving Amoeba- (2007)
  • Author(s): R. Kobayashi, A. Tero, T. Nakagaki
  • Organizer: The 23rd Symposium of the Society of Population Ecology "Spatial Structure and Dynamics of Ecological System"
  • Place of Presentation: Sapporo
  • Year and Date: 2007-10-19
• [Presentation] Dynamical Synchronization in True Slime Mold-Maze Solving Amoeba (2007)
  • Author(s): R. Kobayashi
  • Organizer: The 23rd Symposium of the Society of Population Ecology "Spatial Structure and Dynamics of Ecological System"
  • Place of Presentation: Sapporo, Japan
  • Year and Date: 2007-10-19
• [Presentation] 細胞行動のダイナミクスに学ぶ自律分散制御 (2007)
  • Author(s): 中垣俊之、高木清二、手老篤史、三枝徹、小林亮
  • Organizer: 第一回SICE生物制御システム調査研究会
  • Place of Presentation: 早稲田大学
  • Year and Date: 2007-10-18
• [Presentation] Optimization in an amoeboid system -Networking multiple food-locations- (2007)
  • Author(s): 中垣俊之, S.Takagi, 三枝徹, A.Tero, 小林亮
  • Organizer: European Conference on Complex Systems
  • Place of Presentation: Dresden, Germany
  • Year and Date: 2007-10-04
• [Presentation] A Biologically Motivated Shortest Path Finding Algorithm (2007)
  • Author(s): 小林亮, A.Tero, 中垣俊之, K.Yumiki
  • Organizer: The Workshop on Mathematical Modelling and Analysis of Biological Pattern Formations and the Related Topics
  • Place of Presentation: Nagoya
  • Year and Date: 2007-09-25
• [Presentation] A Biologically Motivated Shortest Path Finding Algorithm (2007)
  • Author(s): R. Kobayashi
  • Organizer: The Workshop on Mathematical Modelling and Analysis of Biological Pattern Formations and the Related Topics
  • Place of Presentation: Nagoya, japan
  • Year and Date: 2007-09-25
• [Presentation] A Biologically Motivated Shortest Path Finding Algorithm (2007)
  • Author(s): 小林亮, A.Tero, 中垣俊之
  • Organizer: Mathematical Modeling and Analysis in Biological and Chemical Systems
  • Place of Presentation: Orsay, France
  • Year and Date: 2007-09-04
• [Presentation] Physarum solver :アメーバに学ぶ計算法-基礎と応用- (2007)
  • Author(s): 中垣俊之、三枝徹、手老篤史、小林亮
  • Organizer: 第13回創発システムシンポジウム-相互作用を考える-
  • Place of Presentation: 富山市
  • Year and Date: 2007-08-17
• [Presentation] Sovling network problem by amoeba : dynamics and computation (2007)
  • Author(s): 中垣俊之, A.Tero, 小林亮, 三枝徹
  • Organizer: Conference on Unconventional Computiong
  • Place of Presentation: Bristol, UK
  • Year and Date: 2007-07-12
• [Presentation] Sovling network problem by amoeba: dynamics and computation (2007)
  • Author(s): T. Nakagaki
  • Organizer: Conference on Unconventional Computiong
  • Place of Presentation: Bristol, UK
  • Year and Date: 2007-07-12
• [Presentation] アメーバ様生物粘菌の賢さとその自律分散的しくみ (2007)
  • Author(s): 中垣俊之、手老篤史、小林亮
  • Organizer: 計測自動制御学会システム・情報部会主催第40回自律分散システム部会研究会
  • Place of Presentation: 北海道大学
  • Year and Date: 2007-06-26
• [Presentation] Modeling of the adaptive network of true slime mold (2007)
  • Author(s): A.Tero, 小林亮, 中垣俊之, 三枝徹
  • Organizer: SIAM Conference on Applications of Dynamical Systems
  • Place of Presentation: Snowbird, Saltlake City, USA
  • Year and Date: 2007-05-29
• [Presentation] Modeling of the adaptive network of true slime mold (2007)
  • Author(s): A. Tero
  • Organizer: SIAM Conference on Applications of Dynamical Systems
  • Place of Presentation: Snowbird, USA
  • Year and Date: 2007-05-29
• [Presentation] 計算するアメーバ-真正粘菌変形体- (2007)
  • Author(s): 小林亮
  • Organizer: 京都算楽会第3回研究会
  • Place of Presentation: 由布市
  • Year and Date: 2007-05-13
• [Book] 理論生物学(分担執筆)(真正粘菌の運動と知性) (2011)
  • Author(s): 小林亮, 中垣俊之
  • Publisher: 共立出版
• [Book] 理論生物学(望月敦編著)真正粘菌の運動と知性(分担執筆) (2011)
  • Author(s): 小林亮、中垣俊之
  • Total Pages: 290
  • Publisher: 共立出版
• [Book] PHPサイエンスワールド新書(粘菌?その驚くべき知性?) (2010)
  • Author(s): 中垣俊之
  • Total Pages: 198
  • Publisher: PHP研究所
• [Book] 粘菌-その驚くべき知性- (2010)
  • Author(s): 中垣俊之
  • Total Pages: 198
  • Publisher: PHPサイエンスワールド新書
• [Book] 「空間」の数理生物学(分担執筆)(フェーズフィールドモデル、シリーズ数理生物学要論巻2) (2009)
  • Author(s): 小林亮
  • Publisher: 共立出版
• [Book] 「フェーズフィールドモデル」、シリーズ 数理生物学要論 巻2「空間」の数理生物学 (2009)
  • Author(s): 小林亮
  • Publisher: 共立出版
• [Book] 自己組織化ハンドブック(「結晶成長の数理」の項、分担執筆) (2009)
  • Author(s): 小林亮
  • Total Pages: 937
  • Publisher: NTS出版
• [Book] シリーズ数理生物学要論 巻2「空間」の数理生物学(第10章、分担執筆) (2009)
  • Author(s): 小林亮
  • Total Pages: 207
  • Publisher: 共立出版
• [Remarks] ホームページ等
  • URL: http://www.kobayashi-lab.jp/kobayashi/intro.html
• [Remarks]
  • URL: http://www.fun.ac.jp/staff/staff_comp/nakagakitoshiyuki.html