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The creation of life-body compatibleness type carbon nanotube device by multi-plasma source and living-body signal measurement

Research Project

Project/Area Number 19340178
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Plasma science
Research InstitutionMusashi Institute of Technology

Principal Investigator

HIRATA Takamichi  Musashi Institute of Technology, 工学部, 准教授 (80260420)

Co-Investigator(Kenkyū-buntansha) SHIMATANI Yuichi  武蔵工業大学, 工学部, 准教授 (20154263)
AKIYA Masahiro  武蔵工業大学, 工学部, 教授 (60231833)
HATAKEYAMA Rikizo  東北大学, 工学(系)研究科(研究院), 教授 (00108474)
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥19,630,000 (Direct Cost: ¥15,100,000、Indirect Cost: ¥4,530,000)
Fiscal Year 2008: ¥7,930,000 (Direct Cost: ¥6,100,000、Indirect Cost: ¥1,830,000)
Fiscal Year 2007: ¥11,700,000 (Direct Cost: ¥9,000,000、Indirect Cost: ¥2,700,000)
Keywords生体埋め込み型バイオチップ / プラズマアクティベーション / OH・COOH基の形成 / 生体適合性・親和性 / 神経幹細胞 / 神経細胞(ニューロン) / 生体埋め込み / 化学修飾 / 培養細胞 / 脳感覚野 / プラズマCVD / 熱CVD / 触媒金属 / OH及びCOOH基の形成比率 / 中枢神経の再生医療
Research Abstract

カーボンナノチューブを塗布・分散した金電極基板を用いて、近年再生医療で注目されている神経幹細胞の培養実験を行った。プラズマアクティベーション処理したCNT上では、無処理に比べて神経幹細胞から神経細胞(ニューロン)への分化・伸長が促進されることが判明した。また、小動物(ラット)を用いた模擬バイオセンサの埋め込み実験を行った結果、接着剤等の選択に問題が多少あるが、全体的に親和性が高いことが判明した。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (13 results)

All 2008 2007 Other

All Journal Article (6 results) (of which Peer Reviewed: 5 results) Presentation (3 results) Remarks (4 results)

  • [Journal Article] Chemical Modification of Carbon Nanotube Based Bio-Nanosensor by Plasma Activation2008

    • Author(s)
      T. Hirata, S. Amiya, M. Akiya, O. Takei, T. Sakai, T. Nakamura, J. K. Tsuzuku, T. Yamamoto, and R. Hatakeyama
    • Journal Title

      Japanese Journal of Applied Physics Vol.47

      Pages: 2067-2071

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Chemical Modification of Carbon Nanotube Based Bio-Nanosensor by Plasma Activation2008

    • Author(s)
      T. Hirata, et al.
    • Journal Title

      Japanese Journal of Applied Physics 47

      Pages: 2067-2071

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Culture of Neural Stem Cells on Carbon Nanotube Based Bio Nanosensor Treated by Plasma-Activation Method2008

    • Author(s)
      T. Hirata, et al.
    • Journal Title

      Proceeding of the International Interdiscipli nary-Symposium on Gaseous and Liquid Plasmas (ISGLP2008) 無

      Pages: 135-138

    • Related Report
      2008 Annual Research Report
  • [Journal Article] ナノスコピックプラズマプロセスによるバイオデバイス構築2007

    • Author(s)
      平田孝道、畠山力三、金子俊郎、岡田健、秋谷昌宏、島谷祐一、一木隆範、赤木貴則
    • Journal Title

      プラズマ・核融合学会誌 第83巻

      Pages: 647-657

    • NAID

      110006381231

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Development of a vitamin-protein sensor based on carbon nanotube hvbrid materials2007

    • Author(s)
      T.Hirata, et. al.
    • Journal Title

      Applied Physics Letters 90

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] ズマプロセスによるバイオデバイス構築2007

    • Author(s)
      平田 孝道, 他
    • Journal Title

      プラズマ・核融合学会誌 83

      Pages: 647-657

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Presentation] Culture of Neural Stem Cells on Carbon Nanotube Based Bio Nanosensor Treated by Plasma-Activation Method2008

    • Author(s)
      T. Hirata, M. Akiya, and T. Sakai,
    • Organizer
      Proceeding of the International Interdisciplinary- Symposium on Gaseous and Liquid Plasmas (ISGLP2008)
    • Place of Presentation
      Sendai (Japan)
    • Year and Date
      2008-09-06
    • Related Report
      2008 Final Research Report
  • [Presentation] Culture and differentiation of neural stem cells on CNT/polymer compound material treated plasma-activation method2008

    • Author(s)
      T. Hirata, et al.
    • Organizer
      NT08 : Ninth International Conference on the Science and Application of Nanotubes
    • Place of Presentation
      モンペリエ(フランス)
    • Year and Date
      2008-07-03
    • Related Report
      2008 Annual Research Report
  • [Presentation] DNA Immobilization on the CNT Bio-Chip Using Plasma-Activation Techniue2008

    • Author(s)
      T.Hirata, et. al.
    • Organizer
      25th Symposium on Plasma Processing
    • Place of Presentation
      山口県山口市
    • Year and Date
      2008-01-24
    • Related Report
      2007 Annual Research Report
  • [Remarks] ホームページ等

    • URL

      http://www.bme.tcu.ac.jp/index.html

    • Related Report
      2008 Final Research Report
  • [Remarks]

    • URL

      http://www.bme.tcu.ac.jp/lab/03/hirata/bme-top.html

    • Related Report
      2008 Final Research Report
  • [Remarks]

    • URL

      http://www.bme.tcu.ac.jp/lab/03/

    • Related Report
      2008 Annual Research Report
  • [Remarks]

    • URL

      http://www.bme.musashi-tech.ac.jp/lab/03/

    • Related Report
      2007 Annual Research Report

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

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