Construction of Magnetic Field-Modulation Near-Field AFM Surface Analyzing System and Its Application to Analysis of Polymer Thin Film-Water Interfaces

• Project/Area Number: 19350055
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Polymer chemistry
• Research Institution: University of Toyama
• Principal Investigator: KITANO Hiromi University of Toyama, 大学院・理工学研究部(工学), 教授 (40115829)
• Co-Investigator(Kenkyū-buntansha): GEMMEI-IDE MAKOTO 富山大学, 大学院・理工学研究部(工学), 助教 (70334711)
• Project Period (FY): 2007 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥18,980,000 (Direct Cost: ¥14,600,000、Indirect Cost: ¥4,380,000); Fiscal Year 2008: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000); Fiscal Year 2007: ¥15,990,000 (Direct Cost: ¥12,300,000、Indirect Cost: ¥3,690,000)
• Keywords: 水 / 高分子膜 / 振動分光 / 磁場 / 赤外光 / 変調 / 赤外分光法 / Raman分光法 / 高分子ブラシ / 水素結合ネットワーク / 分子認識 / 局在表面プラズモン共鳴法 / 低温再結晶化

Research Abstract

高分子超薄膜-液界面のナノスケールでの水和状態に関する情報を、膜表面の微細構造、化学組成、さらには表面電位に関する情報と共にin situで捉えることを目的として、原子間力顕微鏡装置 (AFM) と掃引型核磁気共鳴装置を組み合わせた磁場変調型原子間力顕微鏡表面測定装置 (MFM-AFM) を試作した。さらに、特定官能基に水和した水のスペクトルの実験的な帰属の可能性に関する検討を行った。また、高分子ブラシや自己組織化単分子膜の機能と構造との相関についての検討や、高分子薄膜への収着水の構造解析も併せて行った。

Research Products

• [Journal Article] Anti-biofouling Properties of a Telomer Brush with Pendent Glucosylurea Groups (2009)
  • Author(s): Kitano, H.; Hayashi, A.; Takakura, H.; Suzuki, H.; Saruwatari, Y.; Kanayama, N.
  • Journal Title: Langmuir (in press)
  • Peer Reviewed
• [Journal Article] Anti-Biofouling Property of Polymers with a Carboxybetaine Moiety (2009)
  • Author(s): Tada, S.; Inaba, C.; Mizukami, K.; Fujishita, S.; Gemmei-Ide, M,; Kitano, H.; Mochizuki, A.; Tanaka, M.; Matsunaga, T., Macromol.
  • Journal Title: Biosci 9 Pages: 63-70
  • Peer Reviewed
• [Journal Article] Temperature Responsive Polymer Brush Constructed on a Colloidal Gold Monolayer (2009)
  • Author(s): Kitano, H.; Kago, H.; Matsuura, K., J
  • Journal Title: Colloid Interface Sci 331 Pages: 343-350
  • Peer Reviewed
• [Journal Article] Kinetic study on the binding of lectin to mannose residues in a polymer brush. Kitano, H.; Takahashi (2009)
  • Author(s): Y. ; Mizukami, K. ; Matsuura, K. Colloids Surfaces B
  • Journal Title: Biointerfaces 70 Pages: 91-97
  • Peer Reviewed
• [Journal Article] 生体適合性と水和 (2009)
  • Author(s): 北野博巳 源明誠
  • Journal Title: 高分子 58 Pages: 74-77
  • NAID: 10024759045
• [Journal Article] Anti-Biofouling Property of Polymers with a Carboxybetaine Moiety (2009)
  • Author(s): S. Tada, C. Inaba, K. Mizukami, S. Fujishita, M. Gemmei-Ide, H. Kitano, A. Mochizuki, M. Tanaka, T. Matsunaga
  • Journal Title: Macromolecular Bioscience 9 Pages: 63-70
  • Peer Reviewed
• [Journal Article] 生体適合性と水和 (2009)
  • Author(s): 北野博巳, 源明 誠
  • Journal Title: 高分子 58 Pages: 74-77
  • NAID: 10024759045
• [Journal Article] Structure of Water Incorporated in Amphoteric Polymer Thin Films As Studied by FTIR Spectro- scopy. (2008)
  • Author(s): Kitano, H. ; Nagaoka, K. ; Tada, S. ; Gemmei-Ide, M. ; Tanaka, M
  • Journal Title: Macromol. Biosci 8 Pages: 77-85
  • Peer Reviewed
• [Journal Article] Binding of Ricinus communis agglutinin to a galactose-carrying polymer brush on a colloidal gold monolayer (2008)
  • Author(s): Mizukami, K. ; Takakura, H. ;Matsunaga, T. ; Kitano, H., Colloids Surfaces B
  • Journal Title: Biointerfaces 66 Pages: 110-118
  • Peer Reviewed
• [Journal Article] Interaction of wheat germ agglutinin with an N-acetylglucosamine-carrying telomer brush accumulated on a colloidal gold monolayer (2008)
  • Author(s): Kitano, H. ; Nakada, H. ; Mizukami, K., Colloids Surfaces B
  • Journal Title: Biointerfaces 61 Pages: 17-24
  • Peer Reviewed
• [Journal Article] Drug Assessment Based on Detection of L-Glutamate Released from C6 Glioma Cells Using an Enzyme-Luminescence Method (2008)
  • Author(s): Zakir Hossain, S. M. ; Shinohara, H. ; Kitano, H
  • Journal Title: Anal. Chem 80 Pages: 3762-3768
  • Peer Reviewed
• [Journal Article] Spectroscopic Evidence of Phase Transition of Monomolecular Water in Solid Polystyrene. (2008)
  • Author(s): Gemmei-Ide, M. ; Kitano, H.
  • Journal Title: J. Phys. Chem. B 112 Pages: 2764-2766
  • NAID: 120006395332
  • Peer Reviewed
• [Journal Article] Recrystallization of Water in a Non-Water- Soluble Polymer Examined by Fourier Transform Infrared Spectroscopy : Poly(2-methoxyethyl- acrylate) with Low Water Content (2008)
  • Author(s): Gemmei-Ide, M. ; Kitano, H.
  • Journal Title: J. Phys. Chem,B 112 Pages: 12863-12866
  • NAID: 120006395330
  • Peer Reviewed
• [Journal Article] Crystal Growth of Ice Ih by Re-vapor- deposition and Diffusion Suppression of Mono- molecular Water in a Polymer Solid : Spectro- scopic Observation of Phase Transition of Water Sorbed into Polystyrene (2008)
  • Author(s): Gemmei-Ide, M. ; Kitano, H
  • Journal Title: J. Phys. Chem, B 112 Pages: 13499-13502
  • Peer Reviewed
• [Journal Article] Effect of Zwitterionic Polymers on Wound Healing (2008)
  • Author(s): Fujishita, S. ; Inaba, C. ; Tada, S. ; Gemmei-Ide, M. ; Kitano, H. ; Saruwatari, Y., Biol
  • Journal Title: Pharm. Bull 31 Pages: 2309-2315
  • NAID: 110007005034
  • Peer Reviewed
• [Journal Article] 高分子材料の機能と水和構造の相関 (2008)
  • Author(s): 北野博巳 源明誠
  • Journal Title: 日本接着学会誌 44 Pages: 485-490
  • NAID: 10024920238
  • Peer Reviewed
• [Journal Article] Recrystallization of Water in a Non-Water-Soluble Polymer Examined by Fourier Transform Infrared Spectroscopy : Poly (2-methoxyethyl acrylate) with Low Water Content (2008)
  • Author(s): M. Gemmei-Ide H. Kitano
  • Journal Title: The Journal of Physical Chemistry B 112 Pages: 12863-12866
  • NAID: 120006395330
  • Peer Reviewed
• [Journal Article] Crystal Growth of Ice Ih by Revapor-Deposition and Diffusion Suppression of Monomolecular Water in Polymer Solid : Spectroscopic Observation of Phase Transition of Water Sorbed into Solid Polystyrene (2008)
  • Author(s): M. Gemmei-Ide H. Kitano
  • Journal Title: The Journal of Physical Chemistry B 112 Pages: 13499-13502
  • NAID: 120006395331
  • Peer Reviewed
• [Journal Article] Effect of Zwitterionic Polymers on Wound Healing (2008)
  • Author(s): S. Fujishita, C. Inaba, S. Tada, M. Gemmei-Ide, H. Kitano, Y. Saruwatari
  • Journal Title: Biological & Pharmaceutical Bulletin 31 Pages: 2309-2315
  • NAID: 110007005034
  • Peer Reviewed
• [Journal Article] 高分子材料の機能と水和構造の相関 (2008)
  • Author(s): 北野 博巳, 源明 誠
  • Journal Title: 日本接着学会誌 44 Pages: 485-490
  • NAID: 10024920238
  • Peer Reviewed
• [Journal Article] Interaction of wheat germ agglutinin with an N-acetylglucosamine-carrying telomer brush accumulated on a colloidal gold monolayer (2008)
  • Author(s): H. Kitano, H. Nakada, K. Mizukami
  • Journal Title: Collolds Surfaces B: Biointerfaces 66 Pages: 17-24
  • Peer Reviewed
• [Journal Article] Structure of Water Ihcorporated in Amphoteric Polymer Thin Films As Revealed by FTIR Spectroscopy (2008)
  • Author(s): H. Kitano, K. Nagaoka S. TadaM.Gemmei-Ide, M. Tanaka
  • Journal Title: Macromol.Biosci 12 Pages: 722-726
  • Peer Reviewed
• [Journal Article] Spectroscopic Evidence of Phase Transition of Monomolecular Water in Solid Polystyrene (2008)
  • Author(s): M. Gemmei-Ide, H. Kitano
  • Journal Title: J. Phys. Chem. B 112 Pages: 2764-2766
  • NAID: 120006395332
  • Peer Reviewed
• [Journal Article] Functionalization of Single-walled Carbon Nanotube by the Covalent Modification with Polymer Chains (2007)
  • Author(s): Kitano, H. ; Tachimoto, K. ; Anraku, Y.
  • Journal Title: J. Colloid Interface Sci 306 Pages: 28-33
  • Peer Reviewed
• [Journal Article] Functionalization of Single-walled Carbon Nanotube by the Covalent Modification with Polymer Chains (2007)
  • Author(s): Kitano, H. ; Tachimoto, K. ; Anraku, Y.
  • Journal Title: J. Colloid Interface Sci 56 Pages: 188-196
  • Peer Reviewed
• [Journal Article] Carboxybetaine Polymer Protected Gold Nanoparticles : High Dispersion Stability and Resistance against Non-specific Adsorption of Proteins. (2007)
  • Author(s): Matsuura, K. ; Ohno, K. ; Kagaya, S. ; Kitano, H
  • Journal Title: Macromol. Chem. Phys 208 Pages: 862-873
  • Peer Reviewed
• [Journal Article] Recognition of sugars on surface-bound cap- shaped gold particles modified with a polymer brush (2007)
  • Author(s): Anraku, Y. ; Takahashi, Y. ; Kitano, H. ; Hakari, M., Colloids Surfaces B
  • Journal Title: Biointerfaces 57 Pages: 61-68
  • Peer Reviewed
• [Journal Article] Breaking of Supercooled State of Water by a Nanocavity with Disordered Atomic Configu- ration I : Freezing Behavior of Sorbed Water into Polymethylmethacrylate Film as Examined by Fourier Transform Infrared Spectroscopy (2007)
  • Author(s): Gemmei-Ide, M. ; Motonaga, T. ; Kitano, H
  • Journal Title: J. Phys. Chem 111 Pages: 5533-5535
  • Peer Reviewed
• [Journal Article] Structure of Water in the Vicinity of Amphoteric Polymers As Studied by Raman Spectroscopy (2007)
  • Author(s): Kitano, H. ; Nagaoka, K. ; Tada, S. ; Gemmei-Ide, M.
  • Journal Title: J. Colloid Interface Sci 313 Pages: 461-468
  • Peer Reviewed
• [Journal Article] Real-Time Detection of L-Glutamate Released from C6 Glioma Cells Using a Modified Enzyme-Luminescence Method (2007)
  • Author(s): Zakir Hossain, S. M. ; Shinohara, H. ; Kitano, H
  • Journal Title: Anal. Bioanal. Chem 389 Pages: 1961-1966
  • Peer Reviewed
• [Journal Article] Hydration Changes of Poly(2-(2-methoxy- ethoxy)ethyl methacrylate during Thermo- sensitive Phase Transition in Water (2007)
  • Author(s): Maeda, Y. ; Kubota, T. ; Yamauchi, H. ; Nakaji, T. ; Kitano, H.
  • Journal Title: Langmuir 23 Pages: 11259-11265
  • Peer Reviewed
• [Journal Article] Breaking of the Supercooled State of Water by a Nanocavity with Disordered Atomic Configuration.I: Freezing Behavior of Sorbed Waterinto Polymethylmethacrylate Film AsExamined by Fourier Infrared Spectroscopy (2007)
  • Author(s): M. Gemmei-Ide, T. Motonaga H. Kitano
  • Journal Title: J. Phys. Chem. B 111 Pages: 5533-5535
  • Peer Reviewed
• [Journal Article] Stmcture of Water in the Vichlity of Amphoteric Polymers As Revealed by Raman Spectroscopy (2007)
  • Author(s): H. Kitano, K. Nagaoka, S. Tada, M. Gemmei-Ide
  • Journal Title: J. Colloid Interface Sci 313 Pages: 461-468
  • Peer Reviewed
• [Journal Article] Recognition of Sugars on Surface-bound Cap-shaped Gold Particles Modified with a Polymer Brush (2007)
  • Author(s): Y. Anraku, Y. Takahashi, H. Kitano, M. Hakari
  • Journal Title: Colloidg Surfaces B. Biointerfaces 57 Pages: 61-48
  • Peer Reviewed
• [Journal Article] Carboxybetaine Polymer-Protected Gold Nanoparticles: High DispersionAbilitv and Resistance agains Non-Specific Adsorption of Proteins (2007)
  • Author(s): K. Matsuura, K. ohno, S. Kagaya, H. Kitano
  • Journal Title: Macromol. Chem. Phys 208 Pages: 862-873
  • Peer Reviewed
• [Journal Article] Functionalization of Single-walled Carbon Nanotube by the Covalent Modification with Polymers Chains (2007)
  • Author(s): H. Kitano, K. Tachimoto, Y. Anraku
  • Journal Title: J. Colloid Interface Sci 306 Pages: 28-33
  • Peer Reviewed
• [Journal Article] Resistance of Surface-confined Telomers with Pendent Glucosylurea-Groups-against Non-specific Adsorption of Proteins (2007)
  • Author(s): H. Kitano, M. Gemmei-Ide, Y. Anraku, Y. Saruwatari
  • Journal Title: Collolds Surfaces B: Biointerfaces 56 Pages: 188-196
  • Peer Reviewed
• [Presentation] テレケリック高分子膜表面への繊維芽細胞の付着特性 (2008)
  • Author(s): 源明 誠, 石坂 拓也, 稲葉 央, 北野 博巳
  • Organizer: 第57回高分子学会討論会
  • Place of Presentation: 大阪市立大学
  • Year and Date: 2008-09-24
• [Presentation] 赤外分光法から観た固体高分子中の水の相転移挙動と材料の生体適合性との相関 (2008)
  • Author(s): 源明 誠, 大矢 厚志, 北野 博巳
  • Organizer: 第57回高分子学会討論会
  • Place of Presentation: 大阪市立大学
  • Year and Date: 2008-09-24
• [Presentation] 局在表面プラズモン共鳴法を用いるアルパルチルプロテアーゼのセンシングデバイスの構築 (2008)
  • Author(s): 斉藤 大輔, 今井 直美, 源明 誠, 北野博巳
  • Organizer: 第57回高分子学会年次大会
  • Place of Presentation: パシフィコ横浜
  • Year and Date: 2008-05-28
• [Presentation] テレケリックポリマー表面へのタンパク質吸着/繊維芽細胞付着特性に関する研究 (2008)
  • Author(s): 源明 誠, 稲葉 央, 北野博巳
  • Organizer: 第57回高分子学会年次大会
  • Place of Presentation: パシフィコ横浜
  • Year and Date: 2008-05-28
• [Presentation] 固体高分子中の単分子水の相転移挙動 (2008)
  • Author(s): 源明 誠, 北野博巳
  • Organizer: 第57回高分子学会年次大会
  • Place of Presentation: パシフィコ横浜
  • Year and Date: 2008-05-28
• [Presentation] 赤外分光法による生体適合性高分子材料中の水の相転移に関する研究 (2007)
  • Author(s): 源明 誠・萩原 晃・北野 博巳
  • Organizer: 第56回高分子討論会
  • Place of Presentation: 名古屋工業大学
  • Year and Date: 2007-09-20
• [Presentation] 両性イオン基を有する高分子水溶液中の水構造と生体適合性に関する研究 (2007)
  • Author(s): 稲葉 央・多田 晋・源明 誠・北野 博巳・田中 賢・望月 明・猿渡 欣幸
  • Organizer: 第56回高分子学会年次大会
  • Place of Presentation: 名古屋工業大学
  • Year and Date: 2007-09-20
• [Presentation] 固体高分子中の水の相転移に関する研究 (2007)
  • Author(s): 源明 誠・本永 哲也・北野 博巳
  • Organizer: 第56回高分子学会年次大会
  • Place of Presentation: 国立京都国際会館
  • Year and Date: 2007-05-30
• [Presentation] 両性イオン基を有する高分子の生体適合性に関する研究 (2007)
  • Author(s): 稲葉 央・多田 晋・源明 誠・北野 博巳・田中 賢・望月 明・猿渡 欣幸
  • Organizer: 第56回高分子討論会
  • Place of Presentation: 国立京都国際会館
  • Year and Date: 2007-05-30
• [Book] Sensing Capabilities of Self-assembled Monolayer Using Localized Surface Plasmon Spectroscopy in "Bottom-Up Nanofabrication : Supramolecules, Self-Assemblies, and Organized Films. Vol. 3" (Ariga, K. ; Nalwa, H. S.. Eds.) (2009)
  • Author(s): Kitano, H. ; Mizukami, K.
  • Publisher: American Scientific Publishers
• [Book] 「高分子の化学」(荻野和子 竹内茂彌 柘植秀樹 編)「環境と化学」第2版 第7章 (2009)
  • Author(s): 竹内茂彌 北野博巳
  • Publisher: 東京化学同人
• [Book] Sensing Capabilities of Self-assembled Monolayer Using Localized Surface Plasmon Spectroscopy in “Bottom-Up Nanofabrication : Supramolecules, Self-Assemblies, and Organized Films. Vol. 3" (2009)
  • Author(s): H. Kitano, K. Mizukami
  • Total Pages: 21
  • Publisher: American Scientific Publishers
• [Book] 「高分子の化学」(著者 功刀滋 宮本真敏 前田寧 伊藤研策 福田光完 北野博巳) (2008)
  • Author(s): 北野博巳 功刀滋編
  • Publisher: 三共出版
• [Book] 高分子の化学 (2008)
  • Author(s): 北野, 博巳 功刀, 滋 編著
  • Total Pages: 254
  • Publisher: 三共出版