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Development and application of X-ray differential phase microscopy with X-ray Talbot interferometer

Research Project

Project/Area Number 19360027
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Applied optics/Quantum optical engineering
Research InstitutionThe University of Tokyo

Principal Investigator

MOMOSE Atsushi  The University of Tokyo, 大学院・新領域創成科学研究科, 准教授 (20322068)

Co-Investigator(Kenkyū-buntansha) YASHIRO Wataru  東京大学, 大学院・新領域創成科学研究科, 助教 (10401233)
Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Fiscal Year 2008: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2007: ¥9,360,000 (Direct Cost: ¥7,200,000、Indirect Cost: ¥2,160,000)
KeywordsX線顕微鏡 / シンクロトロン放射光 / 位相計測 / トモグラフィ / CT / 回折格子 / Talbot効果 / Talbot干渉計 / X線 / 位相 / 顕微鏡 / 計測工学
Research Abstract

Using the X-ray phase measurement techniques with X-ray transmission grating(s), including X-ray Talbot interferometry, in combination with an X-ray imaging microscope with a Fresnel zone plate, X-ray phase-sensitive imaging microscopy has been developed, enabling high-sensitive and high-resolution observation for weakly absorbing objects, such as polymers and biological tissues. In addition, by repeating the phase measurement at plural projection directions, three-dimensional image reconstruction of the refractive index (X-ray phase tomography) has also been demonstrated.

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (48 results)

All 2010 2009 2008 2007

All Journal Article (11 results) (of which Peer Reviewed: 6 results) Presentation (37 results)

  • [Journal Article] Hard-X-Ray Phase-Difference Microscopy Using a Fresnel Zone Plate and a Transmission Grating2009

    • Author(s)
      W. Yashiro, Y. Takeda, A. Takeuchi, Y. Suzuki, A. Momose
    • Journal Title

      Phys.Rev.Lett. 103

      Pages: 180801-180801

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] X-ray phase tomography with a Talbot interferometer in combination with an X-ray imaging microscope2009

    • Author(s)
      A. Momose, Y. Takeda, A. Takeuchi, Y. Suzuki
    • Journal Title

      J. Phys : Con.Ser. 186

      Pages: 12044-12044

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] X-ray microscopy for neural circuit reconstruction2009

    • Author(s)
      H. Mizutani, Y. Takeda, A. Momose, A. Takeuchi, T. Takagi
    • Journal Title

      J. Phys : Con.Ser. 186

      Pages: 12092-12092

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Hard-X-Ray Phase-Difference Microscopy Using a Fresnel Zone Plate and a Transmission Grating2009

    • Author(s)
      W.Yashiro, Y.Takeda, A.Takeuchi, Y.Suzuki, A.Momose
    • Journal Title

      Physical Review Letters 103

      Pages: 180801-180801

    • Related Report
      2009 Annual Research Report 2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] X-ray phase tomography with a Talbot interferometer in combination with an X-ray imaging microscope2009

    • Author(s)
      A.Momose, Y.Takeda, A.Takeuchi, Y.Suzuki
    • Journal Title

      J.Phys : Conf.Ser. 186

      Pages: 12044-12044

    • Related Report
      2009 Annual Research Report
  • [Journal Article] X-ray microscopy for neural circuit reconstruction2009

    • Author(s)
      H.Mizutani, Y.Takeda, A.Momose, A.Takeuchi, T.Takagi
    • Journal Title

      J.Phys : Conf.Ser. 186

      Pages: 12092-12092

    • Related Report
      2009 Annual Research Report
  • [Journal Article] X-ray Phase Tomography with a Talbot Interferometer in Combination with an X-ray Imaging Microscope2009

    • Author(s)
      A.Momose, Y.Takeda, A.Takeuchi, Y.Suzuki
    • Journal Title

      Journal of Physics: Conference Series 186

      Pages: 12044-12044

    • Related Report
      2008 Annual Research Report
  • [Journal Article] X-ray Microscopy for Neural Circuit Reconstruction2009

    • Author(s)
      H.Mizutani, Y.Takeda, A.Momose, A.Takeuchi, T.Takagi
    • Journal Title

      Journal of Physics : Conference Series 186

      Pages: 12092-12092

    • Related Report
      2008 Annual Research Report
  • [Journal Article] Differential Phase X-ray Imaging Microscopy with X-ray Talbot Interferometer2008

    • Author(s)
      Y. Takeda, W. Yashiro, T. Hattori, A. Takeuchi, Y. Suzuki, A. Momose
    • Journal Title

      Appl.Phys. Express 1

      Pages: 117002-117002

    • NAID

      10025083432

    • Related Report
      2009 Final Research Report
    • Peer Reviewed
  • [Journal Article] Differential Phase X-ray Imaging Microscopy with X-ray Talbot Interferometer2008

    • Author(s)
      Y. Takeda, W. Yashiro, T. Hattori, A. Takeuchi, Y. Suzuki, A. Momose
    • Journal Title

      Applied Physics Express 1

      Pages: 117002-117002

    • NAID

      10025083432

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] タルボ効果を利用した高分解能X線位相イメージング2007

    • Author(s)
      武田佳彦、高倉樹、鈴木芳生、竹内晃久、百生敦
    • Journal Title

      KEK Proceedings 2007-18

      Pages: 43-45

    • Related Report
      2007 Annual Research Report
  • [Presentation] X線結像顕微鏡における Talbot 効果の定式化とその応用2010

    • Author(s)
      矢代航, 竹内晃久, 鈴木芳生, 百生敦
    • Organizer
      日本物理学会
    • Place of Presentation
      岡山大学
    • Year and Date
      2010-03-20
    • Related Report
      2009 Final Research Report
  • [Presentation] X線結像顕微鏡におけるTalbot効果の定式化とその応用2010

    • Author(s)
      矢代航、竹内晃久、鈴木芳生、百生敦
    • Organizer
      日本物理学会
    • Place of Presentation
      岡山大
    • Year and Date
      2010-03-20
    • Related Report
      2009 Annual Research Report
  • [Presentation] X線位相計測と高感度イメージング応用2010

    • Author(s)
      百生敦
    • Organizer
      応用物理学会
    • Place of Presentation
      東海大
    • Year and Date
      2010-03-19
    • Related Report
      2009 Annual Research Report
  • [Presentation] X-ray phase imaging with gratings2010

    • Author(s)
      A. Momose
    • Organizer
      3rd international bioimaging symposium
    • Place of Presentation
      Okazaki, Japan
    • Year and Date
      2010-01-20
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] X-ray phase-difference microscopy with a phase grating and Fresnel zone plate2010

    • Author(s)
      W.Yashiro, A.Takeuchi, Y.Suzuki, A.Momose
    • Organizer
      3rd international bioimaging symposium
    • Place of Presentation
      Okazaki, Japan
    • Year and Date
      2010-01-20
    • Related Report
      2009 Annual Research Report
  • [Presentation] 位相格子とフレネルゾーンプレートによるX線位相差分顕微鏡の開発2010

    • Author(s)
      矢代航, 竹内晃久, 鈴木芳生, 百生敦
    • Organizer
      日本放射光学会
    • Place of Presentation
      姫路
    • Year and Date
      2010-01-09
    • Related Report
      2009 Final Research Report
  • [Presentation] 位相格子とフレネルゾーンプレートによるX線位相差分顕微鏡の開発2010

    • Author(s)
      矢代航、竹内晃久、鈴木芳生、百生敦
    • Organizer
      放射光学会
    • Place of Presentation
      姫路
    • Year and Date
      2010-01-09
    • Related Report
      2009 Annual Research Report
  • [Presentation] Various applications of Talbot interferometry to X-ray phase imaging2009

    • Author(s)
      A. Momose
    • Organizer
      The 2nd International Workshop on Imaging Techniques with Synchrotron Radiation (ITSR2009)
    • Place of Presentation
      Sanya, China
    • Year and Date
      2009-11-08
    • Related Report
      2009 Final Research Report
  • [Presentation] Various applications of Talbot interferometry to X-ray phase imaging2009

    • Author(s)
      A.Momose
    • Organizer
      The 2nd International Workshop on Imaging Techniques with Synchrotron Radiation(ITSR2009)
    • Place of Presentation
      Sanya, China
    • Year and Date
      2009-11-08
    • Related Report
      2009 Annual Research Report
  • [Presentation] Various applications of Talbot interferometry to X-ray phase imaging2009

    • Author(s)
      百生敦
    • Organizer
      The 2nd International Workshop on Imaging Techniques with Synchrotron Radiation(ITSR2009)
    • Place of Presentation
      Sanya, Hainan, China
    • Year and Date
      2009-11-08
    • Related Report
      2008 Annual Research Report
  • [Presentation] X線結像光学系とX線透過格子の組み合わせによる位相差分顕微鏡2009

    • Author(s)
      矢代航, 武田佳彦, 竹内晃久, 鈴木芳生, 百生敦
    • Organizer
      X線結像光学シンポジウム
    • Place of Presentation
      つくば
    • Year and Date
      2009-11-07
    • Related Report
      2009 Annual Research Report 2009 Final Research Report
  • [Presentation] X線結像光学系とX線透過格子の組み合わせによる位相差分顕微鏡2009

    • Author(s)
      矢代航、武田佳彦、竹内晃久、鈴木芳生、百生敦
    • Organizer
      X線結像光学シンポジウム
    • Place of Presentation
      つくば国際会議場
    • Year and Date
      2009-11-07
    • Related Report
      2008 Annual Research Report
  • [Presentation] X-ray phase difference microscopy using a Fresnel zone plate and a transmission grating2009

    • Author(s)
      W.Yashiro, A.Momose, A.Takeuchi, Y.Suzuki
    • Organizer
      The 10th International Conference on Synchrotron Radiation Instrumentation(SRI09)
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2009-09-29
    • Related Report
      2009 Annual Research Report
  • [Presentation] X-ray phase difference microscopy using a Fresnel zone plate and a transmission grating2009

    • Author(s)
      矢代航, 百生敦, 竹内晃久, 鈴木芳生
    • Organizer
      The 10th International Conference on Synchrotron Radiation Instrumentation(SRI09)
    • Place of Presentation
      Sanya, Hainan, China
    • Year and Date
      2009-09-29
    • Related Report
      2008 Annual Research Report
  • [Presentation] X-ray phase difference microscopy using a Fresnel zone plate and a transmission grating2009

    • Author(s)
      W. Yashiro, A. Momose, A. Takeuchi, Y. Suzuki
    • Organizer
      The 10th International Conference on Synchrotron Radiation Instrumentation (SRI09)
    • Place of Presentation
      Melbourne, Australia
    • Year and Date
      2009-09-28
    • Related Report
      2009 Final Research Report
  • [Presentation] X-ray Interferometry and Phase Imaging2009

    • Author(s)
      百生敦
    • Organizer
      2nd School and Workshop on X-ray Micro and Nanoprobes (XMNP 2009)
    • Place of Presentation
      Palinuro, Salerno, Italy
    • Year and Date
      2009-06-17
    • Related Report
      2008 Annual Research Report
  • [Presentation] X-ray interferometry and phaseimaging2009

    • Author(s)
      A. Momose
    • Organizer
      2nd School and Workshop on X-ray Micro and Nanoprobes (XMNP 2009)
    • Place of Presentation
      Palinuro, Italy
    • Year and Date
      2009-06-16
    • Related Report
      2009 Final Research Report
  • [Presentation] X-ray interferometry and phase imaging2009

    • Author(s)
      A.Momose
    • Organizer
      2nd School and Workshop on X-ray Micro and Nanoprobes(XMNP 2009)
    • Place of Presentation
      Palinuro, Salerno, Italy
    • Year and Date
      2009-06-16
    • Related Report
      2009 Annual Research Report
  • [Presentation] 単一格子X線位相差分顕微鏡による高解像度位相イメージングの試み2009

    • Author(s)
      矢代航, 武田佳彦, 竹内晃久, 鈴木芳生, 百生敦
    • Organizer
      応用物理学会
    • Place of Presentation
      筑波大
    • Year and Date
      2009-03-30
    • Related Report
      2009 Final Research Report
  • [Presentation] 単一格子X線位相差分顕微鏡による高解像度位相イメージングの試み2009

    • Author(s)
      矢代航、武田佳彦、竹内晃久、鈴木芳生、百生敦
    • Organizer
      応用物理学会
    • Place of Presentation
      筑波大学
    • Year and Date
      2009-03-30
    • Related Report
      2008 Annual Research Report
  • [Presentation] X線位相イメージング2008

    • Author(s)
      百生敦
    • Organizer
      日本顕微鏡学会 関西支部 特別企画講演会
    • Place of Presentation
      岡崎コンファレンスセンター
    • Year and Date
      2008-12-21
    • Related Report
      2008 Annual Research Report
  • [Presentation] X線位相イメージング2008

    • Author(s)
      百生敦
    • Organizer
      日本顕微鏡学会 関西支部 特別企画講演会
    • Place of Presentation
      岡崎
    • Year and Date
      2008-12-20
    • Related Report
      2009 Final Research Report
  • [Presentation] Recent Advances in X-ray Phase Imaging for Biomedical Applications2008

    • Author(s)
      A. Momose
    • Organizer
      Medical Sciences Congress 2008
    • Place of Presentation
      Queenstown, New Zealand
    • Year and Date
      2008-11-26
    • Related Report
      2009 Final Research Report 2007 Annual Research Report
  • [Presentation] X-ray Phase-Imaging with Talbot Interferometry2008

    • Author(s)
      A. Momose, W. Yashiro, Y. Takeda
    • Organizer
      The Huangguoshu International Interdisciplinary Conference on Biomedical Mathematics
    • Place of Presentation
      Guizhou, China
    • Year and Date
      2008-11-06
    • Related Report
      2009 Final Research Report
  • [Presentation] X-ray Phase-Imaging with Talbot Interferometry2008

    • Author(s)
      A. Momose, W. Yashiro, Y. Takeda
    • Organizer
      The Huangguoshu International Interdisciplinary Conference on Biomedical Mathematics
    • Place of Presentation
      黄果樹(中国)
    • Year and Date
      2008-11-04
    • Related Report
      2007 Annual Research Report
  • [Presentation] X-ray phase tomography with a Talbot interferometer in combination with an X-ray imaging microscope2008

    • Author(s)
      A. Momose, Y. Takeda, A. Takeuchi, Y. Suzuki
    • Organizer
      9th International Conference on X-Ray Microscopy (XRM2008)
    • Place of Presentation
      Zurich, Switzerland
    • Year and Date
      2008-07-21
    • Related Report
      2009 Final Research Report 2007 Annual Research Report
  • [Presentation] X-ray microscopy for neural circuit reconstruction2008

    • Author(s)
      H. Mizutani, Y. Takeda, A. Momose, A. Takeuchi, T. Takagi
    • Organizer
      9th International Conference on X-Ray Microscopy (XRM2008)
    • Place of Presentation
      Zurich, Switzerland
    • Year and Date
      2008-07-21
    • Related Report
      2009 Final Research Report
  • [Presentation] X-ray Microscopy for Neural Circuit Reconstruction2008

    • Author(s)
      H. Mizutani, Y. Takeda, A. Momose, A. Takeuchi, T. Takagi
    • Organizer
      9th International Conference on X-Ray Microscopy (XRM2008)
    • Place of Presentation
      Zurich, Switzerland
    • Year and Date
      2008-07-21
    • Related Report
      2007 Annual Research Report
  • [Presentation] 神経回路網再構築のための新たなX線イメージング法2008

    • Author(s)
      水谷治央, 武田佳彦, 百生敦, 竹内晃久, 高木利久
    • Organizer
      第31回日本神経科学大会
    • Place of Presentation
      東京
    • Year and Date
      2008-07-09
    • Related Report
      2009 Final Research Report 2007 Annual Research Report
  • [Presentation] 微分位相X線結像顕微鏡を利用したポリマーブレンド相分離構造の観察2008

    • Author(s)
      武田佳彦, 高倉樹, 鈴木芳生, 竹内晃久, 百生敦
    • Organizer
      応用物理学会
    • Place of Presentation
      日本大学
    • Year and Date
      2008-03-29
    • Related Report
      2009 Final Research Report
  • [Presentation] 微分位相X線結像顕微鏡を利用したポリマーブレンド相分離構造の観察2008

    • Author(s)
      武田佳彦, 高倉樹, 鈴木芳生, 竹内晃久, 百生敦
    • Organizer
      応用物理学会
    • Place of Presentation
      日本大学(船橋)
    • Year and Date
      2008-03-29
    • Related Report
      2007 Annual Research Report
  • [Presentation] タルボ効果を利用した高分解能X線位相イメージング2008

    • Author(s)
      武田佳彦, 高倉樹, 鈴木芳生, 竹内晃久, 百生敦
    • Organizer
      PF研究会
    • Place of Presentation
      つくば
    • Year and Date
      2008-01-17
    • Related Report
      2009 Final Research Report
  • [Presentation] タルボ効果を利用した高分解能X線位相イメージング2008

    • Author(s)
      武田佳彦, 高倉樹, 鈴木芳生, 竹内晃久, 百生敦
    • Organizer
      PF研究会:X線位相利用計測の将来展望
    • Place of Presentation
      KEK(つくば)
    • Year and Date
      2008-01-17
    • Related Report
      2007 Annual Research Report
  • [Presentation] X線タルボ干渉計を用いた位相コントラストX線結像顕微鏡によるポリマーブレンド相分離構造の観察2008

    • Author(s)
      武田佳彦, 高倉樹, 矢代航, 竹内晃久, 鈴木芳生, 百生敦
    • Organizer
      日本放射光学会
    • Place of Presentation
      立命館大学
    • Year and Date
      2008-01-14
    • Related Report
      2009 Final Research Report
  • [Presentation] X線タルボ干渉計を用いた位相コントラストX線結像顕微鏡によるポリマーブレンド相分離構造の観察2008

    • Author(s)
      武田佳彦, 高倉樹, 矢代航, 竹内晃久, 鈴木芳生, 百生敦
    • Organizer
      日本放射光学会
    • Place of Presentation
      立命館大学(草津)
    • Year and Date
      2008-01-14
    • Related Report
      2007 Annual Research Report
  • [Presentation] X線 Talbot 干渉計による位相イメージング2007

    • Author(s)
      百生敦
    • Organizer
      第9回X線結像光学シンポジウム
    • Place of Presentation
      中部大学(名古屋)
    • Year and Date
      2007-11-03
    • Related Report
      2007 Annual Research Report
  • [Presentation] X線マイクロCT技術を用いた脳神経細胞の3次元再構築2007

    • Author(s)
      水谷治央, 武田佳彦, 百生敦, 高木利久
    • Organizer
      第30回日本神経科学大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-09-10
    • Related Report
      2009 Final Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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