Theoretical modeling and experimental verification of thermal dispersion for its applications in porous media and exploration of bio-transfer mechanism

• Project/Area Number: 19360099
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Thermal engineering
• Research Institution: Shizuoka University
• Principal Investigator: NAKAYAMA Akira Shizuoka University, 工学部, 教授 (60155877)
• Co-Investigator(Kenkyū-buntansha): KUWAHARA Fujio 静岡大学, 工学部, 准教授 (70215119)
• Project Period (FY): 2007 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥18,330,000 (Direct Cost: ¥14,100,000、Indirect Cost: ¥4,230,000); Fiscal Year 2009: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000); Fiscal Year 2008: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000); Fiscal Year 2007: ¥8,320,000 (Direct Cost: ¥6,400,000、Indirect Cost: ¥1,920,000)
• Keywords: 生体組織 / 多孔質 / 熱分散 / 多孔質体 / 機械的分散 / 濃度計測 / 流れの可視化 / 数値シミュレーション / 多孔質対

Research Abstract

今まで,様々な形で提案されてきた生体組織の熱輸送の式について,多孔質体理論に基づき検討した.局所体積平均理論を用いることで,最小の仮定の下に,三次元一般生体熱移動の式が導かれることを示した.今回初めて対向する動脈と静脈の灌流の効果に加え,機械的分散の効果を加味することに成功した.
この三次元一般生体熱移動の式を用いて,肺癌の冷凍壊死療法における凍結過程のシミュレーションを実施した.本研究で確立した機械的分散のモデルおよび三次元一般生体熱移動の式が,工業的応用や生体輸送機構を考える上で極めて有効であることが分かった.

Research Products

• [Journal Article] Why do we have a bronchial tree with 23 levels of bifurcation? (2009)
  • Author(s): A. Nakayama, F. Kuwahara, Y. Sano
  • Journal Title: HEAT AND MASS TRANSFER Volume:45Issue:3 Pages: 351-354
  • Peer Reviewed
• [Journal Article] A porous media approach for bifurcating flow and mass transfer in a human lung (2009)
  • Author(s): F. Kuwahara, Y. Sano, J.J. Liu, A. Nakayama
  • Journal Title: J. Heat Transfer VOL.131
  • Peer Reviewed
• [Journal Article] A Macroscopic Model for Countercurrent Bioheat Transfer in a Circulatory System (2009)
  • Author(s): A. Nakayama, F. Kuwahara, W. Liu
  • Journal Title: J. POROUS MEDIA Volume:12 Pages: 289-300
  • Peer Reviewed
• [Journal Article] Numerical modeling of a composting process with aeration (2009)
  • Author(s): F. Kuwahara, Y. Sano, A. Nakayama, K. Nakasaki, T. Fukazawa
  • Journal Title: J. Porous Media Vol.12(10) Pages: 927-938
  • Peer Reviewed
• [Journal Article] A study on interstitial heat transfer in consolidated and unconsolidated porous media (2009)
  • Author(s): A. Nakayama, K. Ando, C. Yang, Y. Sano, F. Kuwahara, J. Liu
  • Journal Title: Heat Mass Transfer 45(11) Pages: 1365-1372
  • NAID: 120002235678
  • Peer Reviewed
• [Journal Article] A porous media approach for bifurcating flow and mass transfer in a human lung (2009)
  • Author(s): F.Kuwahara, Y.Sano, J.-L.Liu, A.Nakayama
  • Journal Title: ASME J.Heat Transfer 131
  • Peer Reviewed
• [Journal Article] A Macroscopic Model for Countercurrent Bioheat Transfer in a Circulatory System (2009)
  • Author(s): A.Nakayama, F.Kuwahara, W.Liu
  • Journal Title: J.Porous Media 12 Pages: 289-300
  • Peer Reviewed
• [Journal Article] A study on interstitial heat transfer in consolidated and unconsolidated porous media (2009)
  • Author(s): A.Nakayama, A.Ando, K.Yang
  • Journal Title: Heat and Mass Transfer 45-11 Pages: 1365-1372
  • NAID: 120002235678
  • Peer Reviewed
• [Journal Article] Why do we have a bronchial tree with 23 levels of bifurcation? (2009)
  • Author(s): A. Nakayama, F. Kuwahara, Y. Sano
  • Journal Title: Heat and Mass Transfer 45 Pages: 351-354
  • Peer Reviewed
• [Journal Article] The limiting radius for freezing a tumor during percutaneous cryoablation (2008)
  • Author(s): A. Nakayama, F. Kuwahara, K. Iwata, et. al.
  • Journal Title: JOURNAL OF HEAT Volume:130Issue:11
  • Peer Reviewed
• [Journal Article] A general macroscopic turbulence model for flows in packed beds, channels, pipes, and rod bundles (2008)
  • Author(s): A. Nakayama, F. Kuwahara, J. FLUIDS
  • Journal Title: ENGINEERING Vol.130
  • Peer Reviewed
• [Journal Article] A general bioheat transfer model based on the theory of porous media (2008)
  • Author(s): A. Nakayama, F. Kuwahara
  • Journal Title: Int. J. Heat Mass Transfer Volume:51 Pages: 3190-3199
  • NAID: 120000796549
  • Peer Reviewed
• [Journal Article] A general bioheat transfer model based on the theory of porous media (2008)
  • Author(s): A. Nakayama, F. Kuwahara
  • Journal Title: Int. J. Heat and Mass Transfer 51 Pages: 3190-3199
  • NAID: 120000796549
  • Peer Reviewed
• [Journal Article] The limiting radius for freezing a tumor during percutaneous cryoablation (2008)
  • Author(s): A. Nakayama, Y. Kuwahara, K. Iwata, M. Kawamura
  • Journal Title: ASME Trans. J. Heat Transfer 130
  • Peer Reviewed
• [Journal Article] Concept of equivalent diameter for heat and fluid flow in porous media (2007)
  • Author(s): A.Nakayama, F.Kuwahara and Y.Sano
  • Journal Title: AIChE Journal Vol.53-3 Pages: 732-736
  • Peer Reviewed
• [Journal Article] A lumped parameter heat transfer analysis for composting processes with aeration (2007)
  • Author(s): Nakayama, A., Nakasaki, K., Kuwahara, F., Sano, Y.
  • Journal Title: ASME Trans.J.Heat Transfer Vol.129-7 Pages: 902-906
  • Peer Reviewed
• [Presentation] 多孔質体の機械的分散の画像処理 (2010)
  • Author(s): 寒川哲幹, 桑原不二朗, 中山顕
  • Organizer: 第47回日本伝熱シンポジウム
  • Place of Presentation: 札幌市
• [Presentation] Crossflow-Tubular熱交換器の熱分散 (2010)
  • Author(s): 佐野吉彦(静岡大), 桑原不二朗, 本山英明, 中山顕
  • Organizer: 第47回日本伝熱シンポジウム
  • Place of Presentation: 札幌市
• [Presentation] A porous media approach for complex heat and fluid system (2009)
  • Author(s): A.Nakayama
  • Organizer: IFPFA 2009
  • Place of Presentation: 武漢, 中国
• [Presentation] A mass transfer model for flow architecture of the lung (2008)
  • Author(s): 中山顕
  • Organizer: The Seventh JSME-KSME Thermal and Fluids Engineering
  • Place of Presentation: 札幌
  • Year and Date: 2008-10-16
• [Presentation] フォトクロミック染料を用いた可視化実験 (2007)
  • Author(s): 岡田 信幸
  • Organizer: 日本伝熱学会東海支部第14回伝熱コロキウム
  • Place of Presentation: (財)じばさん三重
  • Year and Date: 2007-12-21