Development of novel micro-reactor systems having synthetic-cellassembly

• Project/Area Number: 19360358
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Reaction engineering/Process system
• Research Institution: Tokyo Institute of Technology
• Principal Investigator: YAMAGUCHI Takeo Tokyo Institute of Technology, 資源化学研究所, 教授 (30272363)
• Project Period (FY): 2007 – 2008
• Project Status: Completed (Fiscal Year 2008)
• Budget Amount: ¥18,590,000 (Direct Cost: ¥14,300,000、Indirect Cost: ¥4,290,000); Fiscal Year 2008: ¥8,840,000 (Direct Cost: ¥6,800,000、Indirect Cost: ¥2,040,000); Fiscal Year 2007: ¥9,750,000 (Direct Cost: ¥7,500,000、Indirect Cost: ¥2,250,000)
• Keywords: マイクロリアクタ / 人工細胞 / 協調システム / 集積システム / グラフト重合 / pH・分子認識ゲート / ノイズキャンセリング / 酵素反応 / 分子認識ゲート

Research Abstract

本研究では、環境応答型マイクロカプセルの開発を行った。マイクロカプセルのシェル部分に環境応答ポリマーをグラフト重合させ、コア部分に酵素を導入することで、人工細胞に見立てたマイクロカプセルを作成した。さらに、逐次的な反応系を持つ複数のマイクロカプセルの連携により、従来型反応器では困難なノイズキャンセリングが実現できることを、数値シミュレーションを用いて証明した。

Research Products

• [Journal Article] A New Free Volume Theory Basedon Microscopic Concept of MolecularCollisions for Penetrant Self-diffusivityin Polymers (2009)
  • Author(s): Hidenori Ohashi,Taichi Ito,TakeoYamaguchi
  • Journal Title: Journal of ChemicalEngineering of Japan 42 Pages: 86-96
  • Peer Reviewed
• [Journal Article] A New Free Volume Theory Based on Microscopic Concept of Molecular Collisions for Penetrant Self-diffusivity in Polymers (2009)
  • Author(s): Hidenori Ohashi, Taichi Ito, Takeo Yamaguchi
  • Journal Title: Journal of Chemical Engineering of Japan 42 Pages: 86-96
  • NAID: 10025305549
  • Peer Reviewed
• [Journal Article] Reverse Response of anIon-recognition Polyampholyte to SpecificIon Signals at Different pHs (2008)
  • Author(s): Nobuo Hara, Ohashi Hidenori, Taichi Ito,Takeo Yamaguchi
  • Journal Title: Macromolecules 42 (4) Pages: 980-986
  • Peer Reviewed
• [Journal Article] An Analysis of PoreSize Using a Straight-Pore MolecularRecognition Ion Gating Membrane (2008)
  • Author(s): Naoko Miyaoi, Hidenori Ohashi, TaichiIto,Takeo Yamaguchi
  • Journal Title: Journalof Chemical Engineering of Japan 41 Pages: 766-770
  • Peer Reviewed
• [Journal Article] Reverse Response of an Ion-recognition Polyampholyte to Specific Ion Signals at Different pHs (2008)
  • Author(s): Nobuo Hara, Ohashi Hidenori, Taichi Ito, Takeo Yamaguchi
  • Journal Title: Macromolecules 42(4) Pages: 980-986
  • Peer Reviewed
• [Journal Article] An Analysis of Pore Size Using a Straight-Pore Molecular Recognition Ion Gating Membrane (2008)
  • Author(s): Naoko Miyaoi, Hidenori Ohashi, Taichi Ito, Takeo Yamaguchi
  • Journal Title: Journal of Chemical Engineering of Japan 41 Pages: 766-770
  • NAID: 10024193036
  • Peer Reviewed
• [Journal Article] Anovel preparation method for obtainingph-responsive core-shell microcapsulereactors (2007)
  • Author(s): Kazuki Akamatsu, Takeo Yamagcuhi
  • Journal Title: Ind. Eng. Chem. Res. 46 Pages: 124-130
  • Peer Reviewed
• [Journal Article] Development of MicrocapsuleReactors with Ion-Responsive MembranesHaving Crownether Receptors (2007)
  • Author(s): Kazuki Akamatsu, Taichi Ito, TakeoYamaguchi
  • Journal Title: J Chem. Eng.Japan 40 Pages: 590-597
  • Peer Reviewed
• [Journal Article] Generation of Osmotic Pressure througha Molecular Recognition Ion GatingMembrane (2007)
  • Author(s): Taichi Ito, Takeo Yamaguchi
  • Journal Title: Trans. Material Res. Soc. Japan 32 Pages: 455-458
  • Peer Reviewed
• [Journal Article] A novel preparation method for obtaining ph-responsive core-shell microcapsule reactors (2007)
  • Author(s): Kazuki Akamatsu, Takeo Yamagcuhi
  • Journal Title: Ind. Eng. Chem. Res. 46 Pages: 124-130
  • Peer Reviewed
• [Journal Article] Development of Microcapsule Reactors with Ion-Responsive Membranes Having Crownether Receptors (2007)
  • Author(s): Kazuki Akamatsu, Taichi Ito, Takeo Yamaguchi
  • Journal Title: J Chem. Eng. Japan, 40 Pages: 590-597
  • Peer Reviewed
• [Journal Article] Generation of Osmotic Pressure through a Molecular Recognition Ion Gating Membrane (2007)
  • Author(s): Taichi Ito, Takeo Yamaguchi
  • Journal Title: Trans. Material Res. Soc. Japan 32 Pages: 455-458
  • NAID: 130007922778
  • Peer Reviewed
• [Presentation] 高分子中の分子拡散性を予測するミクロ自由体積モデルにおけるパラメータシステム検討 (2009)
  • Author(s): 大橋秀伯・伊藤大知・山口猛央
  • Organizer: 化学工学会 第74年会
  • Place of Presentation: 横浜国立大学
• [Presentation] 架橋ゲート膜型バイオセンサー開発における細孔内構造制御 (2009)
  • Author(s): 黒木秀記・大橋秀伯・伊藤大知・山口猛央
  • Organizer: 化学工学会第74年会
  • Place of Presentation: 横浜国立大学
• [Presentation] ミクロな自由体積理論を用いた高分子中の分子拡散性予測 : 種々の高分子系への応用 (2009)
  • Author(s): 大橋秀伯・伊藤 大知・山口猛央
  • Organizer: 高分子材料開発のための俯瞰的シンポジウム2009
  • Place of Presentation: 京都大学桂キャンパス
• [Presentation] 架橋ゲート膜型バイオセンサー開発における細孔内構造制御 (2009)
  • Author(s): 黒木 秀記, 大橋 秀伯, 伊藤 大知, 山口 猛央
  • Organizer: 化学工学会 第7 4年会
  • Place of Presentation: 横浜国立大学
• [Presentation] ミクロな自由体積理論を用いた高分子中の分子拡散性予測:種々の高分子系への応用 (2009)
  • Author(s): 大橋 秀伯, 伊藤 大, 山口 猛央
  • Organizer: 高分子材料開発のための俯瞰的シンポジウム2009
  • Place of Presentation: 京都大学桂キャンパス
• [Presentation] Micro pore fillingmembranes and their unique performances~from Bio-inspired materials to polymerelectrolyte fuel cells (2008)
  • Author(s): Takeo Yamaguchi
  • Organizer: CaliforniaInstitute of Technology (Invited Lecture)
  • Place of Presentation: California Institute ofTechnology, USA
  • Year and Date: 2008-11-12
• [Presentation] Micro pore filling membranes and their unique performances 〜from Bio-inspired materials to polymer electrolyte fuel cells〜 (2008)
  • Author(s): Takeo Yamaguchi
  • Organizer: California Institute of Technology (Invited Lecture)
  • Place of Presentation: California Institute of Technology, USA
  • Year and Date: 2008-11-12
• [Presentation] Pore fillingmembranes and their unique performances~from polymer electrolyte fuel cells tobio-inspired materials (2008)
  • Author(s): Takeo Yamaguchi
  • Organizer: 8thJapan-Korea Symposium on Materials & Interfaces -International Symposium onFrontiers in Chemical Engineering-(Keynote Lecture)
  • Place of Presentation: Sapporo
  • Year and Date: 2008-11-05
• [Presentation] Pore filling membranes and their unique performances 〜from polymer electrolyte fuel cells to bio-inspired materials 〜 (2008)
  • Author(s): Takeo Yamaguchi
  • Organizer: 8th Japan-Korea Symposium on Materials & Interfaces -International Symposium on Frontiers in Chemical Engineering- (Keynote Lecture)
  • Place of Presentation: Sapporo
  • Year and Date: 2008-11-05
• [Presentation] Bio-Inspired MaterialDevelopment according to the Notion of"Material System" and Prediction Tool ofMolecular Diffusivity in PolymericSystems for Material Design (2008)
  • Author(s): Hidenori Ohashi, Taichi Ito, TakeoYamaguchi
  • Organizer: NationalInstitute for Interdisciplinary Science & Technology (Invited Lecture)
  • Place of Presentation: National Institute forInterdisciplinary Science & Technology,India
  • Year and Date: 2008-09-19
• [Presentation] Bio-Inspired Material Development according to the Notion of "Material System"and Prediction Tool of Molecular Diffusivity in Polymeric Systems for Material Design (2008)
  • Author(s): Hidenori Ohashi, Taichi Ito, Takeo Yamaguchi
  • Organizer: Nationa1 Institute for Interdisciplinary Science & Technology (Invited Lecture)
  • Place of Presentation: National Institute for Interdisciplinary Science & Technology, India
  • Year and Date: 2008-09-19
• [Presentation] 高分子中の分子拡散性を予測する新しいミクロモデルの構築 (2008)
  • Author(s): 大橋秀伯・伊藤大知・山口猛央
  • Organizer: ポストシリコン物質・デバイス創製基盤技術アライアンス平成20年度成果報告会
  • Place of Presentation: 北海道大学
• [Presentation] 分子認識イオンゲート膜の創製とデバイス応用 (2008)
  • Author(s): 大橋秀伯・伊藤大知・山口猛央
  • Organizer: ポストシリコン物質・デバイス創製基盤技術アライアンス平成20 年度成果報告会
  • Place of Presentation: 北海道大学
• [Presentation] Developmentof Novel Bioresponsive Gating System usingBiorecognition Crosslinker (2008)
  • Author(s): Hidenori Kuroki, Hidenori Ohashi,Taichi Ito, Takeo Yamaguchi
  • Organizer: International Symposium on EngineeringMicro-/Nano-Materials based onSelf-Assembling and Self-Organization,ISEM2008 Returns
  • Place of Presentation: TheNational Museum of Emerging Science andInnovation (Miraikan), Japan
• [Presentation] Nonlinear Self-Excited Oscillation of aSynthetic Ion Channel-Inspired Membrane (2008)
  • Author(s): 伊藤 大知・大橋 秀伯・山口 猛央
  • Organizer: 膜シンポジウム2008
  • Place of Presentation: 大阪大学豊中キャンパス
• [Presentation] ミクロな自由体積理論を用いた高分子中の分子拡散性予測 : 気体・溶媒から溶質分子まで (2008)
  • Author(s): 大橋 秀伯・伊藤 大知・山口 猛央
  • Organizer: 膜シンポジウム2008
  • Place of Presentation: 大阪大学豊中キャンパス
• [Presentation] Nonlinear Self-ExcitedOscillation of a Synthetic IonChannel-Inspired Membrane (2008)
  • Author(s): Taichi Ito, Hidenori Ohashi, TakeoYamaguchi
  • Organizer: 日韓高分子若手シンポジウム発表(JAPAN-KOREA PolymerYoung Scientist Symposium)
  • Place of Presentation: Niigata
• [Presentation] Development of A NovelMicroscopic Free Volume Theory forSelf-Diffusivity Prediction in PolymerMatrices (2008)
  • Author(s): Hidenori Ohashi, Taichi Ito, TakeoYamaguchi
  • Organizer: 日韓高分子若手シンポジウム発表(JAPAN-KOREA Polymer Young ScientistSymposium)
  • Place of Presentation: Niigata
• [Presentation] 生体分子認識ゲート膜における細孔内グラフトポリマーのナノ構造制御 (2008)
  • Author(s): 黒木 秀記・大橋 秀伯・伊藤 大知・山口 猛央
  • Organizer: 第57回高分子討論会
  • Place of Presentation: 大阪市立大学 杉本キャンパス
• [Presentation] Bio-Inspired MaterialDevelopment according to the Notion of"Material System" and Prediction Tool ofMolecular Diffusivity in PolymericSystems for Material Design (2008)
  • Author(s): Hidenori Ohashi, Taichi Ito, TakeoYamaguchi
  • Organizer: SecondInternational Conference on Polymerblends, Composites, IPNS, Membranes,Polyelectrolytes and Gels : Macro to NanoScales (Invited Lecture)
  • Place of Presentation: India
• [Presentation] 生体分子認識ゲート膜を用いたバイオセンサー開発におけるナノ細孔構造制御 (2008)
  • Author(s): 黒木秀記・大橋秀伯・伊藤大知・山口猛央
  • Organizer: 化学工学会関東支部大会新潟大会2008
  • Place of Presentation: 新潟大学
• [Presentation] Development of a MicroscopicFree Volume Theory for MolecularSelf-Diffusivity Prediction in PolymericSystems (2008)
  • Author(s): Hidenori Ohashi, Taichi Ito, TakeoYamaguchi
  • Organizer: International Congress onMembranes and Membrane Process 2008
  • Place of Presentation: Sheraton Waikiki Hotel, Honolulu, Hawaii, USA
• [Presentation] Development of NobelBiomolecule-Responsive Gating Systemusing Biomolecular Recognition GatingMembrane (2008)
  • Author(s): Hidenori Kuroki, Taichi Ito, Takeo Yamaguchi
  • Organizer: International Congress onMembranes and Membrane Process 2008
  • Place of Presentation: Sheraton Waikiki Hotel,Honolulu, Hawaii, USA
• [Presentation] Fixed-Charge Group-Like Behavior of theCaptured Ion by Crown Ether and Its Effecton the Response of a Molecular RecognitionIon Gating Membrane (2008)
  • Author(s): Taichi Ito, Takeo Yamaguchi
  • Organizer: InternationalCongress on Membranes and Membrane Process2008
  • Place of Presentation: Sheraton Waikiki Hotel, Honolulu, Hawaii, USA
• [Presentation] Micro Pore FillingMembranes and Their Unique Performances~From Bio-inspired Materials to PolymerElectrolyte Fuel Cells (2008)
  • Author(s): Takeo Yamaguchi
  • Organizer: 5thInternational Conference InterfacesAgainst Pollution 2008 (Keynote Lecture)
  • Place of Presentation: Kyoto University
• [Presentation] 生体分子応答ゲート膜におけるナノ細孔構造制御 (2008)
  • Author(s): 黒木秀記・伊藤大知・山口猛央
  • Organizer: 日本膜学会第30回年会
  • Place of Presentation: 東京理科大学 森戸記念館
• [Presentation] 分子認識イオンゲート膜の有機溶媒水溶液中での応答挙動 (2008)
  • Author(s): 伊藤大知・山口猛央
  • Organizer: 化学工学会第73年会
  • Place of Presentation: 静岡
• [Presentation] 浸透圧出力型生体分子認識ゲート膜における細孔内ナノ構造制御 (2008)
  • Author(s): 黒木秀記・伊藤大知・山口猛央
  • Organizer: 化学工学会第73年会
  • Place of Presentation: 静岡
• [Presentation] 分子認識ポリマーを用いた人工アロステリック酵素の開発 (2008)
  • Author(s): 鶴見信幸・伊藤大知・平川秀彦・山口哲志・長棟輝行・山口猛央
  • Organizer: 化学工学会第73年会
  • Place of Presentation: 静岡
• [Presentation] 分子認識イオンゲート膜の創製とデバイス応用 (2008)
  • Author(s): 大橋 秀伯, 伊藤 大知, 山口 猛央
  • Organizer: ポストシリコン物質・デバイス創製基盤技術アライアンス平成20年度成果報告会
  • Place of Presentation: 北海道大学
• [Presentation] Development of Novel Bioresponsive Gating System using Biorecognition Crosslinker (2008)
  • Author(s): Hidenori Kuroki, Hidenori Ohashi, Taichi Ito, Takeo Yamaguchi
  • Organizer: International Symposium on Engineering Micro-/Nano-Materials based on Self-Assembling and Self-Organization, ISEM2008 Returns
  • Place of Presentation: The National Museum of Emerging Science and Innovation(Miraikan), Japan
• [Presentation] Nonlinear Self-Excited Oscillation of a Synthetic Ion Channel-Inspired Membrane (2008)
  • Author(s): 伊藤 大知, 大橋 秀伯, 山口 猛央
  • Organizer: 膜シンポジウム2008
  • Place of Presentation: 大阪大学豊中キャンパス
• [Presentation] Nonlinear Self-Excited Oscillation of a Synthetic Ion Channel-Inspired Membrane (2008)
  • Author(s): Taichi Ito, Hidenori Ohashi, Takeo Yamaguchi
  • Organizer: 日韓高分子若手シンポジウム発表(JAPAN-KOREA Polymer Young Scientist Symposium)
  • Place of Presentation: Niigata
• [Presentation] Development of A Novel Microscopic Free Volume Theory for Self-Diffusivity Prediction in Polymer Matrices (2008)
  • Author(s): Hidenori Ohashi, Taichi Ito, Takeo Yamaguchi
  • Organizer: 日韓高分子若手シンポジウム発表(JAPAN-KOREA Polymer Young Scientist Symposium)
  • Place of Presentation: Niigata
• [Presentation] 生体分子認識ゲート膜における細孔内グラフトポリマーのナノ構造制御 (2008)
  • Author(s): 黒木 秀記, 大橋 秀伯, 伊藤 大知, 山口 猛央
  • Organizer: 第57回 高分子討論会
  • Place of Presentation: 大阪市立大学 杉本キャンパス
• [Presentation] Bio-Inspired Material Development according to the Notion of "Material System"and Prediction Tool of Molecular Diffusivity in Polymeric Systems for MaterialDesign (2008)
  • Author(s): Hidenori Ohashi, Taichi Ito, Takeo Yamaguchi
  • Organizer: Second International Conference on Polymer blends, Composites, IPNS, Membranes, Polyelectrolytes and Gels : Macro to Nano Scales (Invited Lecture)
  • Place of Presentation: India
• [Presentation] Development of a Microscopic Free Volume Theory for Molecular Self-Diffusivity Prediction in Polymeric Systems (2008)
  • Author(s): Hidenori Ohashi, Taichi Ito, Takeo Yamaguchi
  • Organizer: International Congress on Membranes and Membrane Process 2008
  • Place of Presentation: Sheraton Waikiki Hotel, Honolulu, Hawaii, USA
• [Presentation] Development of Nobel Biomolecule-Responsive Gating System using Biomolecular Recognition Gating Membrane (2008)
  • Author(s): Hidenori Kuroki, Taichi Ito, Takeo Yamaguchi
  • Organizer: International Congress on Membranes and Membrane Process 2008
  • Place of Presentation: Sheraton Waikiki Hotel, Honolulu, Hawaii, USA
• [Presentation] Fixed-Charge Group-Like Behavior of the Captured Ion by Crown Ether and Its Effect on the Response of a Molecular Recognition Ion Gating Membrane (2008)
  • Author(s): Taichi Ito, Takeo Yamaguchi
  • Organizer: International Congress on Membranes and Membrane Process 2008
  • Place of Presentation: Sheraton Waikiki Hotel, Honolulu, Hawaii, USA
• [Presentation] Micro Pore Filling Membranes and Their Unique Performances 〜From Bio-inspired Materials to Polymer Electrolyte Fuel Cells〜 (2008)
  • Author(s): Takeo Yamaguchi
  • Organizer: 5th International Conference Interfaces Against Pollution2008 (Keynote Lecture)
  • Place of Presentation: Kyoto University
• [Presentation] 生体分子認識ゲート膜を用いた新規ゲート型生体分子応答システムの開発 (2007)
  • Author(s): 黒木秀記・伊藤大知・山口猛央
  • Organizer: 第18回日本MRS学術シンポジウム
  • Place of Presentation: 東京
  • Year and Date: 2007-12-09
• [Presentation] 「招待講演」細孔中における分子機能の協調~生体システム発想膜から燃料電池まで~ (2007)
  • Author(s): 山口猛央
  • Organizer: 第18回日本MRS学術シンポジウム
  • Place of Presentation: 東京
  • Year and Date: 2007-12-08
• [Presentation] 「招待講演」細孔中における分子機能の協調〜生体システム発想膜から燃料電池まで〜 (2007)
  • Author(s): 山口猛央
  • Organizer: 第18回日本MRS学術シンポジウム
  • Place of Presentation: 東京
  • Year and Date: 2007-12-08
• [Presentation] 「招待講演」多孔基材細孔中フィリングポリマーの物性と応用~燃料電池から生体機能膜模倣まで~ (2007)
  • Author(s): 山口猛央
  • Organizer: 日本油化学会オレエオナノサイエンス部会シンポジウム
  • Place of Presentation: 東京
  • Year and Date: 2007-11-19
• [Presentation] 「招待講演」多孔基材細孔中フィリングポリマーの物性と応用〜燃料電池から生体機能膜模倣まで〜 (2007)
  • Author(s): 山口猛央
  • Organizer: 日本油化学会オレエオナノサイエンス部会シンポジウム
  • Place of Presentation: 東京
  • Year and Date: 2007-11-19
• [Presentation] プラズマグラフト重合法による円筒状細孔を有する多孔膜への機能付加 (Functionalization of porousmembrane having cylindrical pores byplasma-graft polymerization) (2007)
  • Author(s): Yumi Ogino, Hidenori Ohashi, TaichiIto, Takeo Yamaguchi
  • Organizer: 24thConference of Photopolymer Science andTechnology
  • Place of Presentation: 千葉
  • Year and Date: 2007-06-28
• [Presentation] プラズマグラフト重合法による円筒状細孔を有する多孔膜への機能付加(Functionalization of porous membrane having cylindrical pores by plasma-graft polymerization) (2007)
  • Author(s): Yumi Ogino, Hidenori Ohashi, Taichi Ito, Takeo Yamaguchi
  • Organizer: 24th Conference of Photopolymer Science and Technology
  • Place of Presentation: 千葉
  • Year and Date: 2007-06-28
• [Presentation] 生体分子応答浸透圧ジェネレーションシステムを志向したナノ細孔ゲート膜の開発 (2007)
  • Author(s): 黒木秀記・伊藤大知・山口猛央
  • Organizer: 第56回高分子討論会
  • Place of Presentation: 名古屋
• [Presentation] イオン認識性ポリマーを用いた人工アロステリック酵素の開発 (2007)
  • Author(s): 鶴見信幸・伊藤大知・山口哲志・長宗輝行・山口猛央
  • Organizer: 第56回高分子討論会
  • Place of Presentation: 名古屋
• [Presentation] 「展望講演」生体システムから発想した機能性ゲル・システムの構築と応用 (2007)
  • Author(s): 山口猛央
  • Organizer: 化学工学会秋季大会
  • Place of Presentation: 北海道
• [Presentation] イオン認識ゲート膜の浸透圧応答イオン逆転現象 (2007)
  • Author(s): 荻野佑美・大橋秀伯・伊藤大知・山口猛央
  • Organizer: 化学工学会秋季大会
  • Place of Presentation: 北海道
• [Presentation] Preparation ofenzyme-enclosed microcapsule reactors inresponse to specific ion signal (2007)
  • Author(s): Kazuki Akamatsu, Taichi Ito, TakeoYamaguchi
  • Organizer: The 4thConference of Aseanian Membrane Society
  • Place of Presentation: Taipei
• [Presentation] 生体分子応答浸透圧ジェネレーションシステムを志向したナノ細孔ゲート膜の開発 (2007)
  • Author(s): 黒木秀記・伊藤大知・山口猛央
  • Organizer: 第56回局分子討論会
  • Place of Presentation: 名古屋
• [Presentation] 展望講演」生体システムから発想した機能性ゲル・システムの構築と応用 (2007)
  • Author(s): 山口猛央
  • Organizer: 化学工学会秋季大会
  • Place of Presentation: 北海道
• [Presentation] Preparation of enzyme-enclosed microcapsule reactors in response to specific ion signal (2007)
  • Author(s): Kazuki Akamatsu, Taichi Ito, Takeo Yamaguchi
  • Organizer: The 4th Conference of Aseanian Membrane Society
  • Place of Presentation: Taipei
• [Book] 多孔体へのプラズマグラフト重合を用いたバイオ材料システムの開発 (2008)
  • Author(s): 伊藤大知、山口猛央
  • Publisher: サイエンス&テクノロジー, 多孔体の精密制御と機能・物性評価
• [Book] 多孔体の精密制御と機能・物性評価 「多孔体へのプラズマグラフト重合を用いたバイオ材料システムの開発」 (2008)
  • Author(s): 伊藤大知、山口猛央
  • Publisher: サイエンス&テクノロジー