Structure and function of metal-containing sensor proteins that use gas molecules as physiological effectors
| Project/Area Number |
19370059
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Functional biochemistry
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| Research Institution | 大学共同利用機関法人自然科学研究機構(岡崎共通研究施設) (2009)
National Institutes of Natural Sciences Okazaki Research Facilities (2007-2008) |
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Principal Investigator |
AONO Shigetoshi 大学共同利用機関法人自然科学研究機構(岡崎共通研究施設), 岡崎統合バイオサイエンスセンター, 教授 (60183729)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥18,070,000 (Direct Cost: ¥13,900,000、Indirect Cost: ¥4,170,000)
Fiscal Year 2009: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2008: ¥5,850,000 (Direct Cost: ¥4,500,000、Indirect Cost: ¥1,350,000)
Fiscal Year 2007: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
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| Keywords | センサータンパク質 / ヘムタンパク質 / 構造機能相関 / シグナル伝達 / 水素結合ネットワーク / 走化性制御系 / ヘム / グロビンドメイン / 気体分子センサー |
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| Research Abstract |
I have studied gas sensor proteins using oxygen or carbon monoxide as their physiological effector molecules to elucidate their structure and function relationships. This study has revealed a novel biological function of gas molecules as signal molecules and the molecular mechanism of gas sensor proteins.
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Report
(4 results)
Research Products
(78 results)
