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Analyses of common structural motif of rhodopsin family

Research Project

Project/Area Number 19370065
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Biophysics
Research InstitutionNagoya University

Principal Investigator

TSUTOMU Kouyama  Nagoya University, 理学研究科, 教授 (30170210)

Co-Investigator(Kenkyū-buntansha) MURAKAMI Midori  名古屋大学, 理学研究科, 助教 (20324387)
IHARA Kunio  名古屋大学, 遺伝子実験施設, 助教 (90223297)
Project Period (FY) 2007 – 2008
Project Status Completed (Fiscal Year 2008)
Budget Amount *help
¥13,390,000 (Direct Cost: ¥10,300,000、Indirect Cost: ¥3,090,000)
Fiscal Year 2008: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2007: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
Keywords結晶構造解析 / ロドプシン / プロトンポンプ / ハロロドプシン / 視物質 / 古細菌 / バクテリオロドプシン / アーキロドプシン / イカロドプシン / X線結晶構造解析 / イオンポンプ / Gタンパク質共役レセプター / レチナールタンパク質
Research Abstract

高度好塩菌の光駆動プロトン輸送体(バクテリオロドプシン、アーキロドプシン)、光駆動塩素イオン輸送体(ハロロドプシン)、無脊椎動物系の視物質(イカロドプシン)など、異なる機能を有するロドプシン群蛋白質(=7 回膜貫通型レチナール結合蛋白質)を研究対象とし、それらの立体構造ならびに光誘起構造変化を調べ、ロドプシン群蛋白質の機能発現に必須な構造モチーフについての構造学的情報を得ることを目標として研究を展開した。

Report

(3 results)
  • 2008 Annual Research Report   Final Research Report ( PDF )
  • 2007 Annual Research Report
  • Research Products

    (97 results)

All 2009 2008 2007 Other

All Journal Article (25 results) (of which Peer Reviewed: 22 results) Presentation (63 results) Book (2 results) Remarks (6 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] 視物質および古細菌型ロドプシンの結晶化2009

    • Author(s)
      神山 勉
    • Journal Title

      日本結晶学会誌 51

      Pages: 107-111

    • NAID

      10024820477

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] 新しい光受容体の作動機構2009

    • Author(s)
      神山 勉
    • Journal Title

      パリティ 24

      Pages: 68-70

    • Related Report
      2008 Final Research Report
  • [Journal Article] イカロドプシンの結晶構造と無脊椎動物の視覚2009

    • Author(s)
      村上緑
    • Journal Title

      生物物理 49

      Pages: 15-16

    • NAID

      110007044738

    • Related Report
      2008 Final Research Report
  • [Journal Article] Functionally important structural elements of the cyanobacterial clock-related protein Pex2009

    • Author(s)
      S. Kurosawa, R. Murakami, K. Onai, M. Morishita, D. Hasegawa, R. Iwase, T. Uzumaki, F. Hayashi, T. Kitajima-Ihara, S. Sakata, M. Murakami, T. Kouyama, M. Ishiura
    • Journal Title

      Genes Cells 14

      Pages: 1-16

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Functionally important structural elements of the cyanobacterial clock-related protein Pex2009

    • Author(s)
      S. Kurosawa, R. Murakami, K. Onai, M. Morishita, D. Hasegawa, R. Iwase, T. Uzumaki, F. Hayashi, T. Kitaima-Ihara, S. Sakata, M. Murakami, T. Kouyama, M. Ishiura
    • Journal Title

      Genes Cells 14

      Pages: 1-16

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 視物質および古細菌型ロドプシンの結晶化2009

    • Author(s)
      神山勉
    • Journal Title

      日本結晶学会誌 51

      Pages: 107-111

    • NAID

      10024820477

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 新しい光受容体の作動機構2009

    • Author(s)
      神山勉
    • Journal Title

      パリティ 24

      Pages: 68-70

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of xenon binding to a hydrophobic cavity on the proton pumping cycle in bacteriorhodopsin2008

    • Author(s)
      N. Hayakawa, T. Kasahara, D. Hasegawa, K. Yoshimura, M. Murakami, T. Kouyama
    • Journal Title

      J. Mol. Biol 384

      Pages: 812-823

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] スルメイカロドプシンのX 線結晶構造解析2008

    • Author(s)
      村上緑、神山勉
    • Journal Title

      実験医学 26

      Pages: 2237-2240

    • Related Report
      2008 Final Research Report
  • [Journal Article] Crystal structure of squid rhodopsin2008

    • Author(s)
      M. Murakami and T. Kouyama
    • Journal Title

      Nature 453

      Pages: 363-367

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Structural role of bacterioruberin in the trimeric structure of archaerhodopsin-22008

    • Author(s)
      K. Yoshimura and T. Kouyama
    • Journal Title

      J. Mol. Biol 375

      Pages: 1267-1281

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] A halorhodopsin-overproducing mutant isolated from an extremely haloalkaliphilic archaeon Natronomonas pharaonis2008

    • Author(s)
      K. Ihara, A. Narusawa, K. Maruyama, M. Takeguchi, T. Kouyama
    • Journal Title

      FEBS Lett 582

      Pages: 2931-2936

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Salinibacter sensory rhodopsin : sensory rhodopsin I-like protein from a eubacterium2008

    • Author(s)
      T. Kitajima-Ihara, Y. Furutani, D. Suzuki, K. Ihara K, H. Kandori, M. Homma, Y. Sudo
    • Journal Title

      J. Biol. Chem 283

      Pages: 23533-23541

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effect of xenon binding to a hydrophobic cavity on the proton pumping cycle in bacteriorhodopsin2008

    • Author(s)
      N. Hayakawa, T. Kasahara, D. Hasegawa, K. Yoshimura, M. Murakami, T. Kouyama
    • Journal Title

      J. Mol. Biol. 384

      Pages: 812-823

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Crystal structure of squid rhodopsin2008

    • Author(s)
      M. Murakami, T. Kouyama
    • Journal Title

      Nature 453

      Pages: 363-367

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Structural role of bacterioruberin in the trimeric structure of archaerhodopsin-22008

    • Author(s)
      K. Yoshimura, T. Kouyama
    • Journal Title

      J. Mol. Biol. 375

      Pages: 1267-1281

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A halorhodopsin-overproducing mutant isolated from an extremely haloalkaliphilic archaeon Natronomonas pharaonis2008

    • Author(s)
      K. Ihara, A. Narusawa, K. Maruyama, M. Takeguchi, T. Kouyama
    • Journal Title

      FEBS Lett. 582

      Pages: 2931-2936

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Structural Role of Bacterioruberin in the Trimeric Structure of Archaerhodopsin-22008

    • Author(s)
      K. Yoshimura and T. Kouyama
    • Journal Title

      J. Mol. Biol. 375

      Pages: 1267-1281

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Crystallization and crystal properties of squid rhodospin2007

    • Author(s)
      M. Murakami, R. Kitahara, T. Gotoh, and T. Kouyama
    • Journal Title

      Acta Crystallogr F63

      Pages: 475-479

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Halide binding by the D212N mutant of Bacteriorhodopsin affects hydrogen bonding of water in the active site2007

    • Author(s)
      M. Shibata, M Yoshitsugu, N,Mizuide, K. Ihara H,Kandori
    • Journal Title

      Biochemistry 46

      Pages: 7525-7535

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] バクテリオロドプシンのプロトン輸送機構 : 蛋白質中のプロトンと水分子の動き2007

    • Author(s)
      前田章夫、神山勉
    • Journal Title

      蛋白質・核酸・酵素 9, 52

      Pages: 1314-1321

    • NAID

      40015608588

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Journal Article] Crystallization and crystal properties of squid rhodopsin2007

    • Author(s)
      M. Murakami, R. Kitahara, T. Gotoh and T. Kouyama
    • Journal Title

      Acta Cryst. F63

      Pages: 475-279

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] バクテリオロドプシンのプロトン輸送機構:蛋白質中のプロトンと水分子の動き2007

    • Author(s)
      前田章夫、神山勉
    • Journal Title

      蛋白質・核酸・酵素 52

      Pages: 1314-1321

    • NAID

      40015608588

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Halide binding by the D212N mutant of Bacteriorhodopsin affects hydrogen bonding of water in the active site.2007

    • Author(s)
      Shibata M, Yoshitsugu M, Mizaide N, Ihara K, Kandori H.
    • Journal Title

      Biochemistry 46

      Pages: 7525-7535

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] White and H.Stan-Lotter Halorubrum chaoviator sp. Nov., a haloarchaeon isolated from sea salt in Baja California, Mexico, Western Australia and Naxos

    • Author(s)
      R. L.Mancinelli, R.Landheim, C.Sanchez-Porro, M.Dornmayr-Pfaffenhuemer, C. Gruber, A. Legat, A. Ventosa, C. Radax, K. Ihara, M. R
    • Journal Title

      Greece. Int. J. System. Evol. Microbiol (in press)

    • Related Report
      2008 Final Research Report
    • Peer Reviewed
  • [Presentation] イカロドプシン光反応初期中間体の構造解析2009

    • Author(s)
      村上緑, 神山勉
    • Organizer
      第4回日本生物物理学会中部支部討論会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-03-31
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] イカロドプシン光異性化反応の構造解析2009

    • Author(s)
      村上緑
    • Organizer
      シンポジウム : 名大の生物物理の生誕50周年
    • Place of Presentation
      名古屋
    • Year and Date
      2009-03-26
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] Crystal structures of archaeal and invertebrate rhodopsins2008

    • Author(s)
      T. Kouyama
    • Organizer
      Molecular Pharmacology of G Protein-Coupled Receptors 2008
    • Place of Presentation
      Sydney
    • Year and Date
      2008-11-15
    • Related Report
      2008 Final Research Report
  • [Presentation] Crystal structures of archaeal and invertebrate rhodopsins2008

    • Author(s)
      T. Kouyama
    • Organizer
      Molecular Pharmacology of G Protein-Coupled Receptors 2008
    • Place of Presentation
      Sydney, Australia
    • Year and Date
      2008-11-15
    • Related Report
      2008 Annual Research Report
  • [Presentation] X-ray structure of squid rhodopsin2008

    • Author(s)
      M. Murakami
    • Organizer
      International symposium on membrane proteins and high resolution X-ray structural analysis
    • Place of Presentation
      Hyogo
    • Year and Date
      2008-09-01
    • Related Report
      2008 Final Research Report
  • [Presentation] X-ray structure of squid rhodopsin2008

    • Author(s)
      M. Murakami
    • Organizer
      International symposium on membrane proteins and high resolution X-ray structural analysis
    • Place of Presentation
      Hyogo, Japan
    • Year and Date
      2008-09-01
    • Related Report
      2008 Annual Research Report
  • [Presentation] Crystallization of visual pigments and archaeal rhodopsins2008

    • Author(s)
      T. Kouyama, M. Murakami, K. Yoshimura and M. Yamamoto
    • Organizer
      XXI Congress and General Assembly of the International Union of Crystallography
    • Place of Presentation
      Osaka
    • Year and Date
      2008-08-29
    • Related Report
      2008 Final Research Report
  • [Presentation] Crystallization of visual pigments and archaeal rhodopsins2008

    • Author(s)
      T. Kouyama, M. Murakami, K. Yoshimura, M. Yamamoto
    • Organizer
      XXI Congress and General Assembly of the Interaational Union of Crystallography
    • Place of Presentation
      Osaka, Japan
    • Year and Date
      2008-08-29
    • Related Report
      2008 Annual Research Report
  • [Presentation] Dimeric structure of squid rhodopsin2008

    • Author(s)
      M. Murakami and T. Kouyama
    • Organizer
      13th International conference of retinal proteins
    • Place of Presentation
      Barcelona
    • Year and Date
      2008-06-28
    • Related Report
      2008 Final Research Report
  • [Presentation] Protein-lipid interactions in 3D crystals of squid rhodopsin and archaeal rhodopsins2008

    • Author(s)
      T. Kouyama, M. Murakami and K. Yoshimura
    • Organizer
      13th International conference of retinal proteins
    • Place of Presentation
      Barcelona
    • Year and Date
      2008-06-28
    • Related Report
      2008 Final Research Report
  • [Presentation] Dimeric structure of squid rhodopsin2008

    • Author(s)
      M. Murakami, T. Kouyama
    • Organizer
      13th International conference of retinal proteins
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2008-06-18
    • Related Report
      2008 Annual Research Report
  • [Presentation] Protein-lipid interactions in 3D crystals of squid rhodopsin and archaeal rhodopsins2008

    • Author(s)
      T. Kouyama, M. Murakami, K. Yoshimura
    • Organizer
      13th International conference of retinal proteins
    • Place of Presentation
      Barcelona, Spain
    • Year and Date
      2008-06-16
    • Related Report
      2008 Annual Research Report
  • [Presentation] 無脊椎動物のロドプシンおよび古細菌型ロドプシンの構造2008

    • Author(s)
      神山勉
    • Organizer
      第5回GPCR研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-05-09
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] Crystal Structure of Squid Rhodopsin2008

    • Author(s)
      M. Murakami
    • Organizer
      Gordon Research Conference on "LIGAND RECOGNITION & MOLECULAR GATING"
    • Place of Presentation
      Ventura, CA
    • Year and Date
      2008-03-06
    • Related Report
      2008 Final Research Report
  • [Presentation] Crystal Structure of Squid Rhodopsin2008

    • Author(s)
      M. Murakami
    • Organizer
      Gordon Research Conference on "LIGAND RECO GNITION & MOLECULAR GATING"
    • Place of Presentation
      Ventura, CA, USA
    • Year and Date
      2008-03-06
    • Related Report
      2007 Annual Research Report
  • [Presentation] Crystal Structure of Squid Rhodopsin at 2.5A resolution2008

    • Author(s)
      T. Kouyama and M. Murakami
    • Organizer
      GPCR symposium - Frontier on Integral Membrane Proteins in Crystal Structure Determination -
    • Place of Presentation
      Hyogo
    • Year and Date
      2008-02-26
    • Related Report
      2008 Final Research Report
  • [Presentation] Crystal Structure of Squid Rhodopsin at 2.5A resolution2008

    • Author(s)
      T. Kouyama and M. Murakami
    • Organizer
      GPCR symposium - Frontier on Integral Membrane Proteins in Crystal Structure Determination-
    • Place of Presentation
      Hyogo
    • Year and Date
      2008-02-26
    • Related Report
      2007 Annual Research Report
  • [Presentation] Crystallographic studies of squid rhodopsin and archaeal rhodopsins2008

    • Author(s)
      T. Kouyama
    • Organizer
      Gordon Research Conference on "PHOTOSENSORY RECEPTORS & SIGNAL TRANSDUCTION"
    • Place of Presentation
      Ventura, CA
    • Year and Date
      2008-01-29
    • Related Report
      2008 Final Research Report
  • [Presentation] Crystallographic studies of squid rhodopsin and archaeal rhodopsins2008

    • Author(s)
      T. Kouyama
    • Organizer
      Gordon Research Conference on "PHOTOSENSORY RECEPTORS & SIGNAL TRANSDUCTION"
    • Place of Presentation
      Ventura, CA, USA
    • Year and Date
      2008-01-29
    • Related Report
      2007 Annual Research Report
  • [Presentation] 好アルカリ性好塩菌由来Natronomonas pharaonisのハロロドプシンの結晶化2008

    • Author(s)
      竹口優、成澤明洋、井原邦夫、神山勉
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] 古細菌型ロドプシンと無脊椎動物のロドプシンの構造比較2008

    • Author(s)
      神山勉
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] バクテリオロドプシンのアルカリpHでの光誘起構造変化2008

    • Author(s)
      山本昌孝、村上緑、神山勉
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] イカロドプシンのX線結晶構造解析2008

    • Author(s)
      村上緑、神山勉
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Related Report
      2008 Annual Research Report 2008 Final Research Report
  • [Presentation] 古細菌型ロドプシンを発現した大腸菌の膜生理学2008

    • Author(s)
      井原邦夫
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Related Report
      2008 Final Research Report
  • [Presentation] バクテリオロドプシン変異体の二次元結晶構造の高速AFM観察2008

    • Author(s)
      柴田幹大、山下隼人、内橋貴之、山田純也、井原邦夫、神取秀樹、安藤敏夫
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Related Report
      2008 Final Research Report
  • [Presentation] D85N変異体を用いて解析したバクテリオロドプシンのシッフ塩基部位の水素結合構造2008

    • Author(s)
      山田純也、柴田幹大、井原邦夫、神取秀樹
    • Organizer
      日本生物物理学会第46回年会
    • Place of Presentation
      福岡
    • Related Report
      2008 Final Research Report
  • [Presentation] スルメイカロドプシンのX 線結晶構造解析2008

    • Author(s)
      村上緑、神山勉
    • Organizer
      第8回日本蛋白質科学会年会
    • Place of Presentation
      東京
    • Related Report
      2008 Final Research Report
  • [Presentation] クライオ原子間力顕微鏡による凍結割断試料の液浸観察2007

    • Author(s)
      山川奈津子、真塩海里、山本昌孝、五藤俊明、神山勉
    • Organizer
      日本生物物理学会第45回年会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-23
    • Related Report
      2008 Final Research Report 2007 Annual Research Report
  • [Presentation] バクテリオロドプシンを発現した大腸菌の光生理反応2007

    • Author(s)
      井原 邦夫
    • Organizer
      日本生物物理学会第45回年会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-23
    • Related Report
      2007 Annual Research Report
  • [Presentation] スルメイカロドプシンのX線結晶構造解析2007

    • Author(s)
      村上緑、神山勉
    • Organizer
      日本生物物理学会第45回年会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-22
    • Related Report
      2008 Final Research Report 2007 Annual Research Report
  • [Presentation] アーキロドプシン-2の3量体におけるバクテリオルベリンの役割2007

    • Author(s)
      吉村恵子、神山勉
    • Organizer
      日本生物物理学会第45回年会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-21
    • Related Report
      2008 Final Research Report 2007 Annual Research Report
  • [Presentation] バクテリオロドプシンの疎水キャビティに結合する希ガスとその効果2007

    • Author(s)
      早川直紀、村上緑、神山勉
    • Organizer
      日本生物物理学会第45回年会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-21
    • Related Report
      2008 Final Research Report 2007 Annual Research Report
  • [Presentation] バクテリオロドプシン3次元結晶のM 中間体寿命に及ぼす格子力の影響2007

    • Author(s)
      山本昌孝、早川直紀、村上緑、神山勉
    • Organizer
      日本生物物理学会第45回年会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-21
    • Related Report
      2008 Final Research Report 2007 Annual Research Report
  • [Presentation] 高度好塩性アルカリ古細菌Natronomonas pharaonis におけるハロロドプシンの解析2007

    • Author(s)
      成澤明洋、丸山恵太、竹口優、井原邦夫、神山勉
    • Organizer
      日本生物物理学会第45回年会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-21
    • Related Report
      2008 Final Research Report
  • [Presentation] バクテリオロドプシンミュータントL93Aの結晶構造解析2007

    • Author(s)
      樋掛雅則、山本昌孝、早川直紀、井原邦夫、神山勉
    • Organizer
      日本生物物理学会第45回年会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-21
    • Related Report
      2008 Final Research Report 2007 Annual Research Report
  • [Presentation] アーキロドプシン-2のM中間体のX線構造解析2007

    • Author(s)
      藤井隆道、吉村恵子、村上緑、神山勉
    • Organizer
      日本生物物理学会第45回年会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-21
    • Related Report
      2008 Final Research Report
  • [Presentation] 高度好塩性アルカリ古細菌Natronomonas pharaonisにおけるハロロドプシンの解析2007

    • Author(s)
      成澤明洋、丸山恵太、竹口優、井原邦夫、神山勉
    • Organizer
      日本生物物理学会第45回年会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-21
    • Related Report
      2007 Annual Research Report
  • [Presentation] アーキロドプシンー2のM中間体のX線構造解析2007

    • Author(s)
      藤井隆道、吉村恵子、村上緑、神山勉
    • Organizer
      日本生物物理学会第45回年会
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-21
    • Related Report
      2007 Annual Research Report
  • [Presentation] イカロドプシンの結晶構造2007

    • Author(s)
      村上緑、神山勉
    • Organizer
      日本結晶学会2007年度年会
    • Place of Presentation
      東京
    • Year and Date
      2007-12-02
    • Related Report
      2007 Annual Research Report
  • [Presentation] バクテリオロドプシンの光反応サイクルに及ぼすXeガスの影響2007

    • Author(s)
      早川直紀、笠原隆史、長谷川大祐、村上緑、神山勉
    • Organizer
      日本結晶学会2007年度年会
    • Place of Presentation
      東京
    • Year and Date
      2007-12-02
    • Related Report
      2007 Annual Research Report
  • [Presentation] バクテリオロドプシンの光誘起構造変化に及ぼす結晶格子力の影響2007

    • Author(s)
      山本昌孝、早川直紀、村上緑、神山勉
    • Organizer
      日本結晶学会2007年度年会
    • Place of Presentation
      東京
    • Year and Date
      2007-12-02
    • Related Report
      2007 Annual Research Report
  • [Presentation] アーキロドプシン-2の3量体構造におけるバクテリオルベリンの特異的結合2007

    • Author(s)
      吉村恵子、神山勉
    • Organizer
      日本結晶学会2007年度年会
    • Place of Presentation
      東京
    • Year and Date
      2007-12-02
    • Related Report
      2007 Annual Research Report
  • [Presentation] X-ray crystallographic studies of the reaction intermediates of archaeal proton pumps2007

    • Author(s)
      .T. Kouyama
    • Organizer
      Nagoya International Symposium on Science of Molecular Assembly and Biomolecular Systems
    • Place of Presentation
      Nagoya
    • Year and Date
      2007-11-30
    • Related Report
      2008 Final Research Report
  • [Presentation] Trimeric Structure of Archaerhodopsin-2 at 2.1 A Resolution2007

    • Author(s)
      K. Yoshimura, T. Kouyama
    • Organizer
      Nagoya International Symposium on Science of Molecular Assembly and Biomolecular Systems
    • Place of Presentation
      Nagoya
    • Year and Date
      2007-11-30
    • Related Report
      2008 Final Research Report
  • [Presentation] Binding of xenon to a hydrophobic cavity in the cytoplasmic half of bacteriorhodopsin & its effect to the absorption kinetics2007

    • Author(s)
      N. Hayakawa, M. Murakami, T. Kasahara, D. Hasegawa, T. Kouyama
    • Organizer
      Nagoya International Symposium on Science of Molecular Assembly and Biomolecular Systems
    • Place of Presentation
      Nagoya
    • Year and Date
      2007-11-30
    • Related Report
      2008 Final Research Report 2007 Annual Research Report
  • [Presentation] Decay kinetics of the M intermediate of bR in 3D crystals : Influence of the crystal lattice force2007

    • Author(s)
      M. Yamamoto, N. Hayakawa, M. Murakami, T. Kouyama
    • Organizer
      Nagoya International Symposium on Science of Molecular Assembly and Biomolecular Systems
    • Place of Presentation
      Nagoya
    • Year and Date
      2007-11-30
    • Related Report
      2008 Final Research Report
  • [Presentation] X-ray crystallographic studies of the reaction intermediates of archaealproton pumps2007

    • Author(s)
      T. Kouyama
    • Organizer
      Nagoya International Symposium on Science of Molecular Assembly and Biomolecular Systems
    • Place of Presentation
      Nagoya
    • Year and Date
      2007-11-30
    • Related Report
      2007 Annual Research Report
  • [Presentation] Trimeric Structure of Archaerhodopsin-2 at 2.1 Å Resolution2007

    • Author(s)
      K. Yoshimura and T. Kouyama
    • Organizer
      Nagoya International Symposium on Science of Molecular Assembly and Biomolecular Systems
    • Place of Presentation
      Nagoya
    • Year and Date
      2007-11-30
    • Related Report
      2007 Annual Research Report
  • [Presentation] Decay kinetics of the M intermediate of bR in 3D crystals: Influence of the crystal lattice force2007

    • Author(s)
      M. Yamamoto, N. Hayakawa, M. Murakami and T. Kouyama
    • Organizer
      Nagoya International Symposium on Science of Molecular Assembly and Biomolecular Systems
    • Place of Presentation
      Nagoya
    • Year and Date
      2007-11-30
    • Related Report
      2007 Annual Research Report
  • [Presentation] Binding of Noble Gases to a Hydrophobic Cavity in the Cytoplasmic Half of Bacteriorhodopsin2007

    • Author(s)
      N. Hayakawa, M. Murakami, T. Kasahara, D. Hasegawa and T. Kouyama
    • Organizer
      2nd International Symposium on Diffraction Structural Biology 2007
    • Place of Presentation
      東京
    • Year and Date
      2007-11-10
    • Related Report
      2007 Annual Research Report
  • [Presentation] X-ray crystallographic study of squid rhodopsin2007

    • Author(s)
      M. Murakami and T. Kouyama
    • Organizer
      2nd International Symposium on Diffraction Structural Biology 2007
    • Place of Presentation
      東京
    • Year and Date
      2007-11-10
    • Related Report
      2007 Annual Research Report
  • [Presentation] Decay kinetics of the M intermediate of bR in 3D crystals: Influence of the crystal lattice force2007

    • Author(s)
      M. Yamamoto, N. Hayakawa, M. Murakami and T. Kouyama
    • Organizer
      2nd International Symposium on Diffraction Structural Biology 2007
    • Place of Presentation
      東京
    • Year and Date
      2007-11-10
    • Related Report
      2007 Annual Research Report
  • [Presentation] Structures and Dynamics of Archaeal Light-Driven Proton Pumps in 3D Crystals : Effect of Crystal Packing, Lattice Force and Xenon Binding2007

    • Author(s)
      T. Kouyama
    • Organizer
      International Symposium on RETINAL PROTEINS : EXPERIMENTS AND THEORY
    • Place of Presentation
      Bremen, Germany
    • Year and Date
      2007-09-24
    • Related Report
      2008 Final Research Report
  • [Presentation] Trimeric Structure of Archaerhodopsin-2 at 2.1 A Resolution2007

    • Author(s)
      K. Yoshimura, T. Kouyama
    • Organizer
      International Symposium on RETINAL PROTEINS : EXPERIMENTS AND THEORY
    • Place of Presentation
      Bremen, Germany
    • Year and Date
      2007-09-24
    • Related Report
      2008 Final Research Report
  • [Presentation] Crystal Structure of Squid Rhodopsin2007

    • Author(s)
      M. Murakami, T. Kouyama
    • Organizer
      International Symposium on RETINAL PROTEINS : EXPERIMENTS AND THEORY
    • Place of Presentation
      Bremen, Germany
    • Year and Date
      2007-09-24
    • Related Report
      2008 Final Research Report
  • [Presentation] Crystal Structure of Squid Rhodopsin2007

    • Author(s)
      M. Murakami and T. Kouyama
    • Organizer
      International Symposium on RETINAL PROTEINS: EXPERIMENTS AND THEORY
    • Place of Presentation
      Bremen, Germany
    • Year and Date
      2007-09-24
    • Related Report
      2007 Annual Research Report
  • [Presentation] Structures and Dynamics of Archaeal Light-Driven Proton Pumps in 3D Crystals: Effect of Crystal Packing, Lattice Force and Xenon Binding2007

    • Author(s)
      T. Kouyama
    • Organizer
      International Symposium on RETINAL PROTEINS: EXPERIMENTS AND THEORY
    • Place of Presentation
      Bremen, Germany
    • Year and Date
      2007-09-24
    • Related Report
      2007 Annual Research Report
  • [Presentation] Trimeric Structure of Archaerhodopsin-2 at 2.1 Å Resolution2007

    • Author(s)
      K. Yoshimura and T. Kouyama
    • Organizer
      International Symposium on RETINAL PROTEINS: EXPERIMENTS AND THEORY
    • Place of Presentation
      Bremen, Germany
    • Year and Date
      2007-09-24
    • Related Report
      2007 Annual Research Report
  • [Presentation] Importance of bacterioruberin for maintaining the trimer in archaerhodopsin-22007

    • Author(s)
      K. Yoshimura, T. Kouyama
    • Organizer
      2nd International Symposium on Diffraction Structural Biology 2007
    • Place of Presentation
      Tokyo
    • Year and Date
      2007-09-10
    • Related Report
      2008 Final Research Report
  • [Presentation] Binding of Noble Gases to a Hydrophobic Cavity in the Cytoplasmic Half of Bacteriorhodopsin2007

    • Author(s)
      N. Hayakawa, M. Murakami, T. Kasahara, D. Hasegawa, T. Kouyama
    • Organizer
      2nd International Symposium on Diffraction Structural Biology 2007
    • Place of Presentation
      Tokyo
    • Year and Date
      2007-09-10
    • Related Report
      2008 Final Research Report
  • [Presentation] X-ray crystallographic study of squid rhodopsin2007

    • Author(s)
      M. Murakami, T. Kouyama
    • Organizer
      2nd International Symposium on Diffraction Structural Biology 2007
    • Place of Presentation
      Tokyo
    • Year and Date
      2007-09-10
    • Related Report
      2008 Final Research Report
  • [Presentation] Decay kinetics of the M intermediate of bR in 3D crystals : Influence of the crystal lattice force2007

    • Author(s)
      M. Yamamoto, N. Hayakawa, M. Murakami, T. Kouyama
    • Organizer
      2nd International Symposium on Diffraction Structural Biology 2007
    • Place of Presentation
      Tokyo
    • Year and Date
      2007-09-10
    • Related Report
      2008 Final Research Report
  • [Presentation] Importance of bacterioruberin for maintaining the trimer in archaerhodopsin-22007

    • Author(s)
      K. Yoshimura and T. Kouyama
    • Organizer
      2nd International Symposium on Diffraction Structural Biology 2007
    • Place of Presentation
      東京
    • Year and Date
      2007-09-10
    • Related Report
      2007 Annual Research Report
  • [Book] 生物物理学ハンドブック(石渡信一、桂勲、桐野豊、美宅成樹 編)2007

    • Author(s)
      神山勉
    • Publisher
      朝倉書店
    • Related Report
      2008 Final Research Report
  • [Book] 生物物理学ハンドブック2007

    • Author(s)
      神山 勉
    • Total Pages
      700
    • Publisher
      朝倉書店
    • Related Report
      2007 Annual Research Report
  • [Remarks] 新聞報道

    • Related Report
      2008 Final Research Report
  • [Remarks] 中日新聞平成20年5月15日朝刊

    • Related Report
      2008 Final Research Report
  • [Remarks] 新薬開発への鍵のタンパク、立体構造を初解明、名大教授ら、イカ使い成功

    • Related Report
      2008 Final Research Report
  • [Remarks] 日刊工業新聞平成20年5月15日

    • Related Report
      2008 Final Research Report
  • [Remarks] 細胞の情報伝達物質、名大、スルメイカで解明

    • Related Report
      2008 Final Research Report
  • [Remarks] Nagoya University Topics, No.182, 10-11 (2008)

    • Related Report
      2008 Final Research Report
  • [Patent(Industrial Property Rights)] 特許権2008

    • Inventor(s)
      神山勉、村上緑
    • Industrial Property Rights Holder
      神山勉、村上緑
    • Industrial Property Number
      2008-058864
    • Filing Date
      2008-03-09
    • Related Report
      2008 Final Research Report 2007 Annual Research Report

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Published: 2007-04-01   Modified: 2016-04-21  

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