| Budget Amount *help |
¥14,690,000 (Direct Cost: ¥11,300,000、Indirect Cost: ¥3,390,000)
Fiscal Year 2009: ¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2008: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2007: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
|
|---|
| Research Abstract |
Actin was purified from fission yeast cells for the first time, and it was shown to polymerize into filaments that are indistinguishable from muscle actin filaments. The contractile ring actin filaments were visualized and their directionality was determined. Filaments were shown to shorten during contraction of the ring. We proposed that actin first polymerizes at one point in the division plane to both directions, and then the directionality was mixed in the ring prior to contraction. Using cultured fly cells we showed that myosin molecules in the cytoplasm accumulate at the division cortex during cytokinesis.
|
