Budget Amount *help |
¥14,820,000 (Direct Cost: ¥11,400,000、Indirect Cost: ¥3,420,000)
Fiscal Year 2009: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2008: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2007: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
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Research Abstract |
Bacillus subtilis gene products (IseA and YqgA) associated with cell shape were investigated extensively. IseA is a proteinaceous inhibitor against the DL-endopeptidase family and its overexpression led to typical cell filamentation. It is likely that YqgA had some relation with cell wall lytic DL-endopeptidases (LytE, LytF and CwlS). The role of LytE, which is one of the synthetic lethal proteins, is investigated in detail. Moreover, enzymatic properties of B. subtilis CwlK and CwlT are reported.
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