Accurate estimation of amino acid requirement using the potency of specific amino acids to stimulate muscle protein synthesis
| Project/Area Number |
19380149
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Zootechnical science/Grassland science
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| Research Institution | Iwate University |
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Principal Investigator |
KITA Kazumi Iwate University, 農学部, 教授 (20221913)
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| Co-Investigator(Kenkyū-buntansha) |
FUJIMURA Shinobu 新潟大学, 自然科学系, 准教授 (20282999)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥14,040,000 (Direct Cost: ¥10,800,000、Indirect Cost: ¥3,240,000)
Fiscal Year 2009: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2008: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2007: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
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| Keywords | ニワトリ / 筋芽細胞 / タンパク質合成 / アミノ酸 / バリン / メチオニン / グリシン / インスリン様成長因子 / 飼料 / 筋肉 / タンパク質 / 蛋白質合成 / 蛋白質 / IGF-I / IGF type-1レセプター |
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| Research Abstract |
It was found that valine and methionine stimulated protein synthesis when chicken embryo myoblasts were incubated in single amino acid deficient medium. Valine stimulated protein synthesis with elevation of gene expression of insulin-like growth factor type-1 receptor. However, dietary valine supplementation did not improve growth performance of chickens. Supplementation of both methionine and glycine in a low-protein diet improved feed efficiency of broilers.
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Report
(4 results)
Research Products
(11 results)
